| scholarly article | Q13442814 |
| P50 | author | Titia de Lange | Q2436934 |
| John Petrini | Q42603861 | ||
| P2093 | author name string | Michael B Kastan | |
| Jan Karlseder | |||
| Christopher Bakkenist | |||
| Olga K Mirzoeva | |||
| Kristina Hoke | |||
| P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
| ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway | Q22253899 | ||
| ATM-dependent phosphorylation of nibrin in response to radiation exposure | Q22254062 | ||
| Identification of human Rap1: implications for telomere evolution | Q22254239 | ||
| Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres | Q22254585 | ||
| Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks | Q24291265 | ||
| Telomere dysfunction and Atm deficiency compromises organ homeostasis and accelerates ageing | Q59086518 | ||
| The cellular response to DNA double-strand breaks: defining the sensors and mediators | Q63383934 | ||
| ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes | Q24302611 | ||
| Telomere-binding protein TRF2 binds to and stimulates the Werner and Bloom syndrome helicases | Q24304488 | ||
| Activation of the ATM kinase by ionizing radiation and phosphorylation of p53 | Q24311891 | ||
| Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2 | Q24317670 | ||
| Control of human telomere length by TRF1 and TRF2 | Q24554302 | ||
| Structure of the TRFH dimerization domain of the human telomeric proteins TRF1 and TRF2 | Q27634733 | ||
| Crystal structure of the Oxytricha nova telomere end binding protein complexed with single strand DNA | Q27766424 | ||
| Single-stranded DNA arising at telomeres in cdc13 mutants may constitute a specific signal for the RAD9 checkpoint | Q27939822 | ||
| TRF2 Protects Human Telomeres from End-to-End Fusions | Q28111898 | ||
| Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products | Q28145751 | ||
| Pot1, the putative telomere end-binding protein in fission yeast and humans | Q28188476 | ||
| The many substrates and functions of ATM | Q28205055 | ||
| DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation | Q28206029 | ||
| Senescence Induced by Altered Telomere State, Not Telomere Loss | Q28315731 | ||
| DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 | Q28509254 | ||
| p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
| ATM and related protein kinases: safeguarding genome integrity | Q29547735 | ||
| DNA damage foci at dysfunctional telomeres | Q29614811 | ||
| A DNA damage checkpoint response in telomere-initiated senescence | Q29615919 | ||
| Protection of mammalian telomeres | Q29618391 | ||
| p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks | Q30014828 | ||
| ATM associates with and phosphorylates p53: mapping the region of interaction | Q30175960 | ||
| The Mre11 complex is required for ATM activation and the G2/M checkpoint | Q34052273 | ||
| T-loop assembly in vitro involves binding of TRF2 near the 3' telomeric overhang | Q34082359 | ||
| TRF2 recruits the Werner syndrome (WRN) exonuclease for processing of telomeric DNA. | Q34288672 | ||
| Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+). | Q34607461 | ||
| Regulation of genome stability by TEL1 and MEC1, yeast homologs of the mammalian ATM and ATR genes | Q34615334 | ||
| Anti-Ri: an antibody associated with paraneoplastic opsoclonus and breast cancer. | Q34619192 | ||
| Requirement of the MRN complex for ATM activation by DNA damage | Q36267304 | ||
| Different telomere damage signaling pathways in human and mouse cells | Q39647901 | ||
| Monoclonal antibodies generated against recombinant ATM support kinase activity | Q40853073 | ||
| ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response | Q40875819 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | DNA damage | Q5205747 |
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | E240 | |
| P577 | publication date | 2004-08-17 | |
| P1433 | published in | PLOS Biology | Q1771695 |
| P1476 | title | The telomeric protein TRF2 binds the ATM kinase and can inhibit the ATM-dependent DNA damage response | |
| P478 | volume | 2 |
| Q24305452 | A RAP1/TRF2 complex inhibits nonhomologous end-joining at human telomeric DNA ends |
| Q55070647 | A switch-like dynamic mechanism for the initiation of replicative senescence. |
| Q34116944 | A telomeric repeat sequence adjacent to a DNA double-stranded break produces an anticheckpoint |
| Q28117859 | ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres |
| Q34009139 | ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis |
| Q37870855 | ATM protein kinase: the linchpin of cellular defenses to stress |
| Q36156849 | ATM regulates the length of individual telomere tracts in Arabidopsis |
| Q34357377 | ATM signalling and cancer |
| Q40453456 | Accumulation and altered localization of telomere-associated protein TRF2 in immortally transformed and tumor-derived human breast cells. |
| Q34107386 | Alternative lengthening of telomeres: models, mechanisms and implications |
| Q33900715 | An increase in telomere sister chromatid exchange in murine embryonic stem cells possessing critically shortened telomeres |
| Q38331044 | AtTBP2 and AtTRP2 in Arabidopsis encode proteins that bind plant telomeric DNA and induce DNA bending in vitro |
| Q92756102 | Back to the future: The intimate and evolving connection between telomere-related factors and genotoxic stress |
| Q34977480 | CHK2 kinase in the DNA damage response and beyond |
| Q36662986 | Chromatin structure in telomere dynamics |
| Q36360651 | DNA damage in telomeres and mitochondria during cellular senescence: is there a connection? |
| Q37058277 | DNA damage response at functional and dysfunctional telomeres |
| Q35900920 | DNA damage responses in neural cells: Focus on the telomere |
| Q64387962 | DNA double-strand breaks are not sufficient to initiate recruitment of TRF2 |
| Q28507823 | DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion |
| Q36245188 | DNA repair and recombination functions in Arabidopsis telomere maintenance |
| Q92980463 | DNA-dependent protein kinase in telomere maintenance and protection |
| Q37767830 | Defending the end zone: studying the players involved in protecting chromosome ends |
| Q39631135 | Detailed Analysis of DNA Repair and Senescence Marker Kinetics Over the Life Span of a Human Fibroblast Cell Line |
| Q38398034 | Detecting ATM-dependent chromatin modification in DNA damage response |
| Q46336609 | Differences in the recruitment of DNA repair proteins at subtelomeric and interstitial I-SceI endonuclease-induced DNA double-strand breaks |
| Q21090064 | Diminished telomeric 3' overhangs are associated with telomere dysfunction in Hoyeraal-Hreidarsson syndrome |
| Q37785995 | Dynamics of telomeric chromatin at the crossroads of aging and cancer |
| Q33613985 | Effect of telomere proximity on telomere position effect, chromosome healing, and sensitivity to DNA double-strand breaks in a human tumor cell line |
| Q62604419 | Effects of hTERT on metal ion-induced genomic instability |
| Q30439002 | Endogenous hSNM1B/Apollo interacts with TRF2 and stimulates ATM in response to ionizing radiation |
| Q35080631 | Essential role for the TRF2 telomere protein in adult skin homeostasis |
| Q27324256 | Femtosecond near-infrared laser microirradiation reveals a crucial role for PARP signaling on factor assemblies at DNA damage sites |
| Q64106199 | Genetic analyses of aplastic anemia and idiopathic pulmonary fibrosis patients with short telomeres, possible implication of DNA-repair genes |
| Q37114930 | Genetic dissection of the mechanisms underlying telomere-associated diseases: impact of the TRF2 telomeric protein on mouse epidermal stem cells |
| Q36144711 | Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition. |
| Q40073650 | High Mobility Group A2 protects cancer cells against telomere dysfunction |
| Q50137448 | How stem cells keep telomeres in check |
| Q38122351 | How will telomeric complex be further contributed to our longevity? - the potential novel biomarkers of telomere complex counteracting both aging and cancer |
| Q41952546 | Human RAP1 inhibits non-homologous end joining at telomeres |
| Q33635574 | Human RECQL1 participates in telomere maintenance |
| Q40466921 | Human telomeric protein TRF2 associates with genomic double-strand breaks as an early response to DNA damage. |
| Q24529072 | Involvement of human MOF in ATM function |
| Q34765484 | LIM Protein Ajuba Participates in the Repression of the ATR-Mediated DNA Damage Response |
| Q40041009 | Lack of TRF2 in ALT cells causes PML-dependent p53 activation and loss of telomeric DNA. |
| Q37198572 | Living on a break: cellular senescence as a DNA-damage response |
| Q35942459 | MRX-dependent DNA damage response to short telomeres |
| Q39078422 | Mechanisms of oncogene-induced genomic instability. |
| Q36296137 | Mechanisms of telomere loss and their consequences for chromosome instability |
| Q37992814 | Methods of studying telomere damage induced by quadruplex-ligand complexes |
| Q33937189 | Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging |
| Q42020833 | Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas |
| Q34076281 | Molecular targeting of TRF2 suppresses the growth and tumorigenesis of glioblastoma stem cells |
| Q34176919 | Multifunctional role of ATM/Tel1 kinase in genome stability: from the DNA damage response to telomere maintenance |
| Q36104368 | Multiple Pathways Control the Reactivation of Telomerase in HTLV-I-Associated Leukemia |
| Q24594847 | Multiple roles of ATM in monitoring and maintaining DNA integrity |
| Q28506028 | Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages |
| Q35614009 | Need telomere maintenance? Call 911 |
| Q37874368 | Never-ageing cellular senescence |
| Q37783683 | Nuclear imaging in three dimensions: A unique tool in cancer research |
| Q34411779 | Nucleolar organization, ribosomal DNA array stability, and acrocentric chromosome integrity are linked to telomere function |
| Q26995219 | Oxidative stress, DNA damage, and the telomeric complex as therapeutic targets in acute neurodegeneration |
| Q34483600 | PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres |
| Q35526524 | PIF1 disruption or NBS1 hypomorphism does not affect chromosome healing or fusion resulting from double-strand breaks near telomeres in murine embryonic stem cells |
| Q33878962 | PRL-3 promotes telomere deprotection and chromosomal instability |
| Q88477742 | Photobiomodulation effects on mRNA levels from genomic and chromosome stabilization genes in injured muscle |
| Q89411750 | Platinum Complexes Can Bind to Telomeres by Coordination |
| Q36360594 | Poly(ADP-ribosyl)ation in mammalian ageing |
| Q33309165 | Pot1 and cell cycle progression cooperate in telomere length regulation |
| Q36299151 | Processing by MRE11 is involved in the sensitivity of subtelomeric regions to DNA double-strand breaks |
| Q38324390 | Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia |
| Q33789158 | Protection and replication of telomeres in fission yeast |
| Q33293671 | Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. |
| Q38133962 | Push back to respond better: regulatory inhibition of the DNA double-strand break response |
| Q35638929 | RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin. |
| Q39310284 | REST-dependent expression of TRF2 renders non-neuronal cancer cells resistant to DNA damage during oxidative stress |
| Q35818204 | Rap1 is indispensable for TRF2 function in etoposide-induced DNA damage response in gastric cancer cell line |
| Q42652989 | Reconstitution of human shelterin complexes reveals unexpected stoichiometry and dual pathways to enhance telomerase processivity |
| Q28074230 | Redox control of senescence and age-related disease |
| Q39732620 | Regulation of Epstein-Barr virus origin of plasmid replication (OriP) by the S-phase checkpoint kinase Chk2. |
| Q39578922 | Requirement of DDX39 DEAD box RNA helicase for genome integrity and telomere protection |
| Q41633913 | Retrotransposon-derived p53 binding sites enhance telomere maintenance and genome protection |
| Q33883012 | Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS |
| Q33558275 | SIRT6 interacts with TRF2 and promotes its degradation in response to DNA damage. |
| Q35922154 | Shelterin Protects Chromosome Ends by Compacting Telomeric Chromatin |
| Q24601577 | Shelterin complex and associated factors at human telomeres |
| Q36948528 | Spontaneous tumor development in bone marrow-rescued DNA-PKcs(3A/3A) mice due to dysfunction of telomere leading strand deprotection |
| Q37399843 | Squelching glioblastoma stem cells by targeting REST for proteasomal degradation |
| Q37742751 | Stop pulling my strings - what telomeres taught us about the DNA damage response |
| Q27938428 | Subtelomeric proteins negatively regulate telomere elongation in budding yeast |
| Q34883924 | Subtelomeric regions in mammalian cells are deficient in DNA double-strand break repair |
| Q35121429 | T-oligo as an anticancer agent in colorectal cancer |
| Q34119771 | TRF1 and TRF2 differentially modulate Rad51-mediated telomeric and nontelomeric displacement loop formation in vitro |
| Q40304525 | TRF2 dysfunction elicits DNA damage responses associated with senescence in proliferating neural cells and differentiation of neurons. |
| Q40365410 | TRF2 inhibition promotes anchorage-independent growth of telomerase-positive human fibroblasts. |
| Q35928861 | TRF2 is required for repair of nontelomeric DNA double-strand breaks by homologous recombination. |
| Q24301264 | TRF2 overexpression diminishes repair of telomeric single-strand breaks and accelerates telomere shortening in human fibroblasts |
| Q35589168 | Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis |
| Q64911093 | Telomerase and Telomeres in Endometrial Cancer. |
| Q37002134 | Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells |
| Q40209443 | Telomerase-independent regulation of ATR by human telomerase RNA. |
| Q37579210 | Telomere Recognition and Assembly Mechanism of Mammalian Shelterin |
| Q36103575 | Telomere biology: integrating chromosomal end protection with DNA damage response |
| Q33302426 | Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect |
| Q33658678 | Telomere disruption results in non-random formation of de novo dicentric chromosomes involving acrocentric human chromosomes |
| Q40696254 | Telomere dynamics and fusion of critically shortened telomeres in plants lacking DNA ligase IV |
| Q36676871 | Telomere dysfunction and DNA-PKcs deficiency: characterization and consequence |
| Q24635882 | Telomere dysfunction and chromosome instability |
| Q34172479 | Telomere length and regulatory proteins in human skeletal muscle with and without ongoing regenerative cycles. |
| Q34689235 | Telomere length, stem cells and aging |
| Q60054366 | Telomere length-dependent transcription and epigenetic modifications in promoters remote from telomere ends |
| Q28590806 | Telomere protection mechanisms change during neurogenesis and neuronal maturation: newly generated neurons are hypersensitive to telomere and DNA damage |
| Q90424102 | Telomere repeat-binding factor 2 binds extensively to extra-telomeric G-quadruplexes and regulates the epigenetic status of several gene promoters |
| Q27004080 | Telomere shortening in human diseases |
| Q44841828 | Telomere shortening is correlated with the DNA damage response and telomeric protein down-regulation in colorectal preneoplastic lesions |
| Q37445974 | Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining |
| Q81334638 | Telomere-binding factors and general DNA repair |
| Q34768068 | Telomeres and aging |
| Q29615353 | Telomeres and human disease: ageing, cancer and beyond |
| Q53310015 | Telomeres and telomerase as targeted therapies in cancer treatment |
| Q61814949 | Telomeres in Plants and Humans: Not So Different, Not So Similar |
| Q34595437 | Telomeres, chromosome instability and cancer |
| Q33740892 | Telomeres: protecting chromosomes against genome instability |
| Q35749321 | Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells |
| Q37419279 | Telomeric armor: the layers of end protection |
| Q33959427 | Telomeric protein TRF2 protects Holliday junctions with telomeric arms from displacement by the Werner syndrome helicase. |
| Q38450799 | Telomeric repeat-containing RNA TERRA: a noncoding RNA connecting telomere biology to genome integrity |
| Q33266104 | Tetrahymena POT1a regulates telomere length and prevents activation of a cell cycle checkpoint |
| Q24338204 | The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair |
| Q35844875 | The Caenorhabditis elegans Rad17 homolog HPR-17 is required for telomere replication |
| Q92965735 | The DNA-damage response and nuclear events as regulators of nonapoptotic forms of cell death |
| Q37114814 | The Drosophila modigliani (moi) gene encodes a HOAP-interacting protein required for telomere protection. |
| Q64086139 | The Emerging Roles of TERRA in Telomere Maintenance and Genome Stability |
| Q34127693 | The MRN complex in double-strand break repair and telomere maintenance |
| Q28538526 | The RSF1 histone-remodelling factor facilitates DNA double-strand break repair by recruiting centromeric and Fanconi Anaemia proteins |
| Q41458958 | The crosstalk of telomere dysfunction and inflammation through cell-free TERRA containing exosomes. |
| Q36761196 | The epigenetic regulation of mammalian telomeres |
| Q42474850 | The function of classical and alternative non-homologous end-joining pathways in the fusion of dysfunctional telomeres |
| Q38937982 | The long and the short of TRF2 in neurogenesis |
| Q39208134 | The many facets of homologous recombination at telomeres |
| Q36192029 | The mechanism of telomere protection: a comparison between Drosophila and humans. |
| Q33682203 | The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1. |
| Q34649915 | The role of ATM in the deficiency in nonhomologous end-joining near telomeres in a human cancer cell line |
| Q33883503 | The telomere binding protein TRF2 induces chromatin compaction |
| Q43077721 | The telomere deprotection response is functionally distinct from the genomic DNA damage response. |
| Q30845462 | The telomeric DNA damage response occurs in the absence of chromatin decompaction |
| Q81024710 | The yeast VPS genes affect telomere length regulation |
| Q35855540 | Therapeutic doses of hydroxyurea cause telomere dysfunction and reduce TRF2 binding to telomeres |
| Q33894381 | To fuse or not to fuse: how do checkpoint and DNA repair proteins maintain telomeres? |
| Q41049545 | Transcription regulation of CDKN1A (p21/CIP1/WAF1) by TRF2 is epigenetically controlled through the REST repressor complex. |
| Q33422242 | Trf1 is not required for proliferation or functional telomere maintenance in chicken DT40 cells |
| Q39355466 | Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction. |
| Q47927337 | Upregulation and CpG island hypomethylation of the TRF2 gene in human gastric cancer |
| Q33255919 | Vertebrate POT1 restricts G-overhang length and prevents activation of a telomeric DNA damage checkpoint but is dispensable for overhang protection |
| Q92128675 | X-rays Activate Telomeric Homologous Recombination Mediated Repair in Primary Cells |
| Q64231030 | ZBTB10 binds the telomeric variant repeat TTGGGG and interacts with TRF2 |
| Q34420523 | Zscan4 interacts directly with human Rap1 in cancer cells regardless of telomerase status |
| Q64100105 | c-Myc activation promotes cofilin-mediated F-actin cytoskeleton remodeling and telomere homeostasis as a response to oxidant-based DNA damage in medulloblastoma cells |
| Q39212563 | p300-mediated acetylation of TRF2 is required for maintaining functional telomeres |
| Q34616697 | p53 governs telomere regulation feedback too, via TRF2. |
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