The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro

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The acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1037517787
P356DOI10.1186/1475-2875-2-14
P932PMC publication ID194860
P698PubMed publication ID12848898
P5875ResearchGate publication ID10672048

P50authorThomas J. HudsonQ3525236
P2093author name stringMichael L Koenig
Maryanne Vahey
Geoffrey S Dow
P2860cites workRegulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alphaQ24540258
Effect of sample size and P-value filtering techniques on the detection of transcriptional changes induced in rat neuroblastoma (NG108) cells by mefloquineQ24806854
Response of neurons to an irreversible inhibition of endoplasmic reticulum Ca(2+)-ATPase: relationship between global protein synthesis and expression and translation of individual genesQ28366272
Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controlsQ29547730
Mefloquine for malaria chemoprophylaxis 1992-1998: a review.Q33669693
CNS adverse events associated with antimalarial agents. Fact or fiction?Q34062133
Mechanisms of capacitative calcium entryQ34330249
The endoplasmic reticulum: a multifunctional signaling organelleQ35051249
Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damageQ38201300
Mefloquine concentration profiles during prophylactic dose regimensQ39144087
Population pharmacokinetics of mefloquine in patients with acute falciparum malariaQ39465442
Impact of viral infection on the gene expression profiles of proliferating normal human peripheral blood mononuclear cells infected with HIV type 1 RF.Q39545369
Effects of mefloquine on Ca2+ uptake by crude microsomes of rabbit skeletal muscle.Q40934369
The ER-overload response: activation of NF-kappa B.Q41361813
Control of Ca2+ homeostasis in neuronal cells.Q41390664
Ionomycin enhances Ca2+ influx by stimulating store-regulated cation entry and not by a direct action at the plasma membraneQ41461138
Cerebral uptake of mefloquine enantiomers in fatal cerebral malaria.Q41924602
In vitro neuroprotection against glutamate-induced toxicity by pGlu-Glu-Pro-NH(2) (EEP).Q43851015
Mefloquine distribution in postmortem casesQ48010361
Glutamate receptor-induced 45Ca2+ accumulation in cortical cell culture correlates with subsequent neuronal degenerationQ48300242
Stereoselective passage of mefloquine through the blood-brain barrier in the rat.Q48584373
Effects of mefloquine on Ca2+ uptake and release by dog brain microsomesQ73283506
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttoxic encephalopathyQ7830379
mefloquineQ736270
neurotoxicityQ3338704
P304page(s)14
P577publication date2003-06-12
P1433published inMalaria JournalQ15749954
P1476titleThe acute neurotoxicity of mefloquine may be mediated through a disruption of calcium homeostasis and ER function in vitro
P478volume2

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cites work (P2860)
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