In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii

scientific article

In vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1032829822
P356DOI10.1186/1472-6750-3-15
P932PMC publication ID222906
P698PubMed publication ID13129437
P5875ResearchGate publication ID10413320

P50authorLennart HammarströmQ5786999
Susanna RicciQ56721689
Gianni PozziQ56721702
Donata MedagliniQ56839963
Paola BossùQ60043687
P2093author name stringTiziana Maggi
Li Xu
Diana Boraschi
Paolo Ruggiero
Aldo Tagliabue
Giovanni Macchia
P2860cites workDevelopment and function of T cells in mice rendered interleukin-2 deficient by gene targetingQ24318910
Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10Q28179431
Interleukin-1 receptor antagonist: role in biologyQ28271409
Ulcerative colitis-like disease in mice with a disrupted interleukin-2 geneQ28593669
Functional and ethnic association of allele 2 of the interleukin-1 receptor antagonist gene in ulcerative colitisQ30304298
Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA.Q30453928
Human IL-1 receptor antagonist from Escherichia coli: large-scale microbial growth and protein purificationQ31972219
Potential treatment of osteoarthritis by gene therapyQ33651413
Mucosal delivery of murine interleukin-2 (IL-2) and IL-6 by recombinant strains of Lactococcus lactis coexpressing antigen and cytokineQ33756245
Probiotics and inflammatory bowel diseasesQ33816844
Proinflammatory cytokinesQ33913139
Immunogenicity of the B monomer of Escherichia coli heat-labile toxin expressed on the surface of Streptococcus gordonii.Q34003291
Gene therapy of chronic inflammatory diseaseQ34079566
Inflammatory bowel disease: immunodiagnostics, immunotherapeutics, and ecotherapeuticsQ34141280
Neutralization of endogenous IL-1 receptor antagonist exacerbates and prolongs inflammation in rabbit immune colitisQ34236293
Interleukin-1 receptor antagonist gene therapy for arthritisQ34442700
Immunotherapeutic approaches to inflammatory bowel diseasesQ34451989
Influence of interleukin-1 receptor antagonist gene polymorphism on diseaseQ34461355
Functions of interleukin 1 receptor antagonist in gene knockout and overproducing miceQ37306765
Intranasal immunization with recombinant Lactococcus lactis secreting murine interleukin-12 enhances antigen-specific Th1 cytokine production.Q39741884
Human interleukin-1 receptor antagonist: large-scale expression in Bacillus brevis 47-5Q.Q40915995
Inhibitory activity of IL-1 receptor antagonist depends on the balance between binding capacity for IL-1 receptor type 1 and IL-1 receptor type II.Q41115990
Interleukin-2 deficient mice: a new model to study autoimmunity and self-toleranceQ41126096
Transfected type II interleukin-1 receptor impairs responsiveness of human keratinocytes to interleukin-1.Q41267810
Binding of IL-1 beta to IL-1R type II at single cell levelQ41667053
Cytokines in inflammatory bowel diseaseQ41730146
Vaginal immunization with recombinant gram-positive bacteria.Q41731866
Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammationQ42258741
A specific receptor antagonist for interleukin 1 prevents Escherichia coli ‐induced shock in rabbitsQ43740171
The microbicide cyanovirin-N expressed on the surface of commensal bacterium Streptococcus gordonii captures HIV-1.Q44854412
Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-1beta-induced beta-cell impairment and activation of islet cell apoptosis in vitroQ45862217
Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injuryQ45881303
Human IL-1Ra gene transfer into human synovial fibroblasts is chondroprotective.Q45881466
In vivo suppression of early experimental osteoarthritis by interleukin-1 receptor antagonist using gene therapyQ45882179
Treatment of rheumatoid arthritis with IL-1 inhibitorsQ45890242
Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammationQ46516903
Increased serum amyloid a levels reflect colitis severity and precede amyloid formation in IL-2 knockout miceQ46812863
Inflammatory bowel disease: etiology and pathogenesisQ47899867
Colonic explant production of IL-1and its receptor antagonist is imbalanced in inflammatory bowel disease (IBD).Q47901523
Interleukin-1, interleukin-1 receptors and interleukin-1 receptor antagonistQ47912627
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.Q49073992
Genetic engineering of Streptococcus gordonii for the simultaneous display of two heterologous proteins at the bacterial surface.Q54545165
Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domainsQ57988358
Interleukin-1 receptor antagonist reduces mortality from endotoxin shockQ59092106
Method and parameters for genetic transformation of Streptococcus sanguis challisQ60920185
Commensal bacteria as vectors for mucosal vaccines against sexually transmitted diseases: vaginal colonization with recombinant streptococci induces local and systemic antibodies in miceQ61454672
A host-vector system for heterologous gene expression in Streptococcus gordoniiQ62671433
The international standards for interleukin-1 alpha and interleukin-1 beta. Evaluation in an international collaborative studyQ68012009
Clinical trial to assess the safety, feasibility, and efficacy of transferring a potentially anti-arthritic cytokine gene to human joints with rheumatoid arthritisQ71503443
Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expressionQ71548098
Novel genetic association between ulcerative colitis and the anti-inflammatory cytokine interleukin-1 receptor antagonistQ72271510
Recombinant human interleukin 1 receptor antagonist in the treatment of patients with sepsis syndrome. Results from a randomized, double-blind, placebo-controlled trial. Phase III rhIL-1ra Sepsis Syndrome Study GroupQ72472826
Therapy of mucosal candidiasis by expression of an anti-idiotype in human commensal bacteriaQ73035266
In situ delivery of passive immunity by lactobacilli producing single-chain antibodiesQ74381949
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
Streptococcus gordoniiQ7623352
P304page(s)15
P577publication date2003-09-17
P1433published inBMC BiotechnologyQ15753225
P1476titleIn vivo mucosal delivery of bioactive human interleukin 1 receptor antagonist produced by Streptococcus gordonii
P478volume3

Reverse relations

cites work (P2860)
Q37896455Bio-inspired, bioengineered and biomimetic drug delivery carriers
Q38806283Bioengineered probiotics as a new hope for health and diseases: an overview of potential and prospects
Q40436195Clinical and microbiological responses of volunteers to combined intranasal and oral inoculation with a Streptococcus gordonii carrier strain intended for future use as a group A streptococcus vaccine
Q54440505Comparison of transformation protocols in Streptococcus gordonii and evaluation of native promoter strength using a multiple-copy plasmid.
Q36316890Delivery of therapeutic proteins to the mucosa using genetically modified microflora
Q49339110Engineering bacteria for diagnostic and therapeutic applications
Q34911427IL-1 family in breast cancer: potential interplay with leptin and other adipocytokines
Q38116457IL-1Ra and its delivery strategies: inserting the association in perspective.
Q37258771Inflammatory bowel disease: mechanisms, redox considerations, and therapeutic targets.
Q24799750Mucosal delivery of anti-inflammatory IL-1Ra by sporulating recombinant bacteria
Q89493327Nanoparticle-Mediated Drug Delivery Systems For The Treatment Of IBD: Current Perspectives
Q92668932Nanoparticulate Drug Delivery Systems Targeting Inflammation for Treatment of Inflammatory Bowel Disease

Search more.