The cyclophilins

scientific article

The cyclophilins is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P6179Dimensions Publication ID1017906616
P356DOI10.1186/GB-2005-6-7-226
P3181OpenCitations bibliographic resource ID839018
P932PMC publication ID1175980
P698PubMed publication ID15998457
P5875ResearchGate publication ID7746779

P50authorJoseph HeitmanQ28324587
P2093author name stringPing Wang
P2860cites workCyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cellsQ24290922
Point mutations in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanismQ24313422
A cyclophilin-related protein involved in the function of natural killer cellsQ24320071
Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilinQ24338951
Regulation of the tyrosine kinase Itk by the peptidyl-prolyl isomerase cyclophilin AQ24534698
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexesQ24535752
Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilinQ24536083
X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domainQ24562985
Two structures of cyclophilin 40: folding and fidelity in the TPR domainsQ27632191
Structural characterization of a proline-driven conformational switch within the Itk SH2 domainQ27639877
Global analysis of protein localization in budding yeastQ27653962
Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin AQ27731514
Yeast cyclophilin: isolation and characterization of the protein, cDNA and geneQ27930440
Cyclophilin A is localized to the nucleus and controls meiosis in Saccharomyces cerevisiaeQ27930786
The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene programQ27931213
The CYP2 gene of Saccharomyces cerevisiae encodes a cyclosporin A-sensitive peptidyl-prolyl cis-trans isomerase with an N-terminal signal sequenceQ27932827
Calcineurin is essential in cyclosporin A- and FK506-sensitive yeast strainsQ27933866
Cyclophilin A peptidyl-prolyl isomerase activity promotes ZPR1 nuclear exportQ27936211
Cyclophilin A and Ess1 interact with and regulate silencing by the Sin3-Rpd3 histone deacetylaseQ27936501
All cyclophilins and FK506 binding proteins are, individually and collectively, dispensable for viability in Saccharomyces cerevisiaeQ27937279
A Saccharomyces cerevisiae cyclophilin resident in the endoplasmic reticulumQ27937753
Identification of two CyP-40-like cyclophilins in Saccharomyces cerevisiae, one of which is required for normal growthQ27939546
Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell deathQ28242641
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell deathQ28242653
Determination of enzymatic catalysis for the cis-trans-isomerization of peptide binding in proline-containing peptidesQ28267643
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexesQ28277749
Cyclophilin A and FKBP12 interact with YY1 and alter its transcriptional activityQ28288097
A nuclear RNA-binding cyclophilin in human T cellsQ28300122
Two cyclophilin A homologs with shared and distinct functions important for growth and virulence of Cryptococcus neoformansQ28367275
Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin AQ28379060
Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerizationQ28568395
Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteinsQ29618460
Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and BQ29618922
Cyclophilin: a specific cytosolic binding protein for cyclosporin AQ29620548
Crystal structure of recombinant human T-cell cyclophilin A at 2.5 A resolutionQ30195572
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopyQ30195613
The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsinsQ33262317
Peptidyl-prolyl cis-trans isomerases, a superfamily of ubiquitous folding catalystsQ33608244
Cyclophilins and their possible role in the stress responseQ33815808
Catalysis of cis/trans isomerization in native HIV-1 capsid by human cyclophilin AQ34024214
The intranuclear prolactin/cyclophilin B complex as a transcriptional inducerQ34067496
Functional association of cyclophilin A with HIV-1 virionsQ34326356
Cyclophilin-40, a protein with homology to the P59 component of the steroid receptor complex. Cloning of the cDNA and further characterizationQ34366402
Properties of the permeability transition pore in mitochondria devoid of Cyclophilin D.Q34406704
Cyclophilin D as a drug targetQ35181284
Peptidylprolyl cis/trans isomerases (immunophilins): biological diversity--targets--functionsQ35181418
Structures of immunophilins and their ligand complexesQ35181439
Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcriptionQ35861172
Prolyl isomerases in yeastQ35880640
A case study of proline isomerization in cell signalingQ35969143
Target cell cyclophilin A modulates human immunodeficiency virus type 1 infectivityQ37596441
Specific incorporation of cyclophilin A into HIV-1 virionsQ38302257
Role of cyclophilin B in activation of interferon regulatory factor-3.Q40447336
A second cyclophilin-related gene in Saccharomyces cerevisiaeQ40515307
Cyclophilin-A is involved in excitotoxin-induced caspase activation in rat neuronal B50 cells.Q40743807
Cellular functions of immunophilinsQ41075701
FK-506- and CsA-sensitive activation of the interleukin-2 promoter by calcineurinQ41618754
Prolyl isomerase requirement for the expression of functional homo-oligomeric ligand-gated ion channelsQ41660474
Immunophilins: beyond immunosuppressionQ42537553
Calcineurin is required for virulence of Cryptococcus neoformansQ42617596
Calcineurin regulatory subunit is essential for virulence and mediates interactions with FKBP12-FK506 in Cryptococcus neoformansQ43544077
The yeast cyclophilin multigene family: purification, cloning and characterization of a new isoformQ44264151
Immunophilins and parvulins. Superfamily of peptidyl prolyl isomerases in ArabidopsisQ44817003
The cyclophilin homolog ninaA is required in the secretory pathwayQ44879878
Cyclophilin A regulates TCR signal strength in CD4+ T cells via a proline-directed conformational switch in Itk.Q45016183
Two new cyclophilins from Fusarium sambucinum and Aspergillus niger: resistance of cyclophilin/cyclosporin A complexes against proteolysisQ46833668
The cyclophilin component of the unactivated estrogen receptor contains a tetratricopeptide repeat domain and shares identity with p59 (FKBP59).Q48114865
Absconding with the Chaperone: Essential Cyclophilin–Gag Interaction in HIV-1 VirionsQ57201983
Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from alpha-factor arrest in yeastQ59064521
Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activityQ67534468
The N-terminal cyclophilin-homologous domain of a 150-kilodalton tumor recognition molecule exhibits both peptidylprolyl cis-trans-isomerase and chaperone activitiesQ72668891
Conservation of Hsp90 macromolecular complexes in Saccharomyces cerevisiaeQ72724151
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectenzymeQ8047
membrane proteinQ423042
cell surface receptorQ2476074
drug receptorsQ58688845
P304page(s)226
P577publication date2005-01-01
2005-06-27
P1433published inGenome BiologyQ5533480
P1476titleThe cyclophilins
P478volume6

Reverse relations

cites work (P2860)
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Q47125734Human Cyclophilin B forms part of a multi-protein complex during erythrocyte invasion by Plasmodium falciparum
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Q36994671Persistent gammaherpesvirus replication and dynamic interaction with the host in vivo
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Q39742401Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant
Q28533585Phosphorylation at serines 216 and 221 is important for Drosophila HeT-A Gag protein stability
Q64256709Plant-Mediated Silencing of the Whitefly Cyclophilin B and Heat Shock Protein 70 Impairs Insect Development and Virus Transmission
Q39579921Preclinical characterization of naturally occurring polyketide cyclophilin inhibitors from the sanglifehrin family
Q36114901Prognosis of sepsis induced by cecal ligation and puncture in mice improved by anti-Clonorchis Sinensis cyclopholin a antibodies
Q34325686Proline: the distribution, frequency, positioning, and common functional roles of proline and polyproline sequences in the human proteome
Q37428826Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378.
Q42738057Rct1, a nuclear RNA recognition motif-containing cyclophilin, regulates phosphorylation of the RNA polymerase II C-terminal domain
Q64103610Reference genes selection for Calotropis procera under different salt stress conditions
Q33846534Regulation of nuclear translocation of the Myb1 transcription factor by TvCyclophilin 1 in the protozoan parasite Trichomonas vaginalis.
Q35569376Regulator of Calcineurin 1 Isoform 4 (RCAN1.4) Is Overexpressed in the Glomeruli of Diabetic Mice
Q59809218SIRT3 a Major Player in Attenuation of Hepatic Ischemia-Reperfusion Injury by Reducing ROS via Its Downstream Mediators: SOD2, CYP-D, and HIF-1
Q37112241Secreted cyclophilin A, a peptidylprolyl cis-trans isomerase, mediates matrix assembly of hensin, a protein implicated in epithelial differentiation.
Q28510022Severe osteogenesis imperfecta in cyclophilin B-deficient mice
Q38754264Shutting down the pore: The search for small molecule inhibitors of the mitochondrial permeability transition
Q34355820Signal transduction triggered by iron to induce the nuclear importation of a Myb3 transcription factor in the parasitic protozoan Trichomonas vaginalis
Q37448419Silencing of a putative immunophilin gene in the cattle tick Rhipicephalus (Boophilus) microplus increases the infection rate of Babesia bovis in larval progeny
Q37187968Spliceosomal immunophilins
Q26801686Steroid Receptor-Associated Immunophilins: A Gateway to Steroid Signalling
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Q35672949Structural basis for activation of calcineurin by calmodulin
Q52332915Structural basis of interaction between dimeric cyclophilin 1 and Myb1 transcription factor in Trichomonas vaginalis.
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Q26825245Suppression of coronavirus replication by cyclophilin inhibitors
Q42860076Synthesis and biological evaluation of [d-lysine]8cyclosporin A analogs as potential anti-HCV agents
Q35758733The Activation of Phytophthora Effector Avr3b by Plant Cyclophilin is Required for the Nudix Hydrolase Activity of Avr3b.
Q27312479The Arabidopsis thaliana immunophilin ROF1 directly interacts with PI(3)P and PI(3,5)P2 and affects germination under osmotic stress
Q36631422The Genomes of Three Uneven Siblings: Footprints of the Lifestyles of Three Trichoderma Species
Q27489053The Isomerase Active Site of Cyclophilin A Is Critical for Hepatitis C Virus Replication
Q36146320The Mitochondrial Permeability Transition Pore: Channel Formation by F-ATP Synthase, Integration in Signal Transduction, and Role in Pathophysiology.
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Q34162254The TPR domain in the host Cyp40-like cyclophilin binds to the viral replication protein and inhibits the assembly of the tombusviral replicase
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Q35768080The cyclophilin DIAGEOTROPICA has a conserved role in auxin signaling
Q42545449The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1-/- myopathic mice.
Q59245625The dengue virus non-structural protein 1 (NS1) is secreted from mosquito cells in association with the intracellular cholesterol transporter chaperone caveolin complex
Q28085108The emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's disease
Q27322887The genome of tolypocladium inflatum: evolution, organization, and expression of the cyclosporin biosynthetic gene cluster
Q47412629The immunophilin repertoire of Plasmodiophora brassicae and functional analysis of PbCYP3 cyclophilin
Q37021772The isolation of novel mesenchymal stromal cell chemotactic factors from the conditioned medium of tumor cells
Q28279895The mitochondrial permeability transition from yeast to mammals
Q37163574The mitochondrial permeability transition pore and ischemia-reperfusion injury
Q38106976The mitochondrial permeability transition pore: a mystery solved?
Q28248925The mitochondrial permeability transition pore: molecular nature and role as a target in cardioprotection
Q37195017The molecular composition of the mitochondrial permeability transition pore
Q40709485The oligomycin-sensitivity conferring protein of mitochondrial ATP synthase: emerging new roles in mitochondrial pathophysiology
Q43670135The peptidyl prolyl isomerase cyclophilin A localizes at the centrosome and the midbody and is required for cytokinesis
Q36400274The relationship between the expression of VEGF, EGFR, and HER-2 mRNA in esophageal squamous cell carcinoma (ESCC) and clinicopathological features of different ethnic groups in Xinjiang
Q38088350The secretory pathway: exploring yeast diversity
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