Phosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibers

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Phosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1289/EHP.5945
P932PMC publication ID1241436
P698PubMed publication ID12676607
P5875ResearchGate publication ID7656715

P2093author name stringYasuo Morimoto
Masato Matsuoka
Hideki Igisu
P2860cites workDiseases caused by asbestos: mechanisms of injury and disease developmentQ23911125
DNA-dependent protein kinase is activated by nicks and larger single-stranded gapsQ64389705
Asbestos causes stimulation of the extracellular signal-regulated kinase 1 mitogen-activated protein kinase cascade after phosphorylation of the epidermal growth factor receptorQ71900044
p53 protein accumulation in lung carcinomas of patients exposed to asbestos and tobacco smokeQ72105420
Analysis of cell cycle disruptions in cultures of rat pleural mesothelial cells exposed to asbestos fibersQ73966594
Activation-induced cell death in human peripheral blood lymphocytes after stimulation with silicate in vitroQ74563073
New developments in the multi-site phosphorylation and integration of stress signalling at p53Q77768552
Mechanisms of Cr(VI) induced p53 activation: the role of phosphorylation, mdm2 and ERKQ23922086
p53, the cellular gatekeeper for growth and divisionQ27860990
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2Q28254119
The complexity of p53 modulation: emerging patterns from divergent signalsQ28284854
Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in miceQ28344105
Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the ratQ28392966
The molecular basis of asbestos induced lung injuryQ28394122
The DNA-dependent protein kinase: requirement for DNA ends and association with Ku antigenQ28608938
Identification of a novel inhibitor of mitogen-activated protein kinase kinaseQ29616448
SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1Q29620495
Mitogen-activated protein kinases: specific messages from ubiquitous messengersQ30303652
Regulation of p53 in response to DNA damageQ33807801
Phosphorylation of human p53 by p38 kinase coordinates N-terminal phosphorylation and apoptosis in response to UV radiationQ33891341
Strategies for manipulating the p53 pathway in the treatment of human cancer.Q34076012
p53: death starQ34103258
Multiple roles of the tumor suppressor p53.Q34493866
DNA damage-inducible genes as biomarkers for exposures to environmental agentsQ34638769
p53, Cip1, and Gadd153 expression following treatment of A549 cells with natural and man-made vitreous fibersQ34639501
Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmanninQ34663629
Oxygen radicals and asbestos-mediated diseaseQ35031381
DNA damage induces phosphorylation of the amino terminus of p53Q35199554
The role of free radicals in asbestos-induced diseasesQ36072961
Asbestos induces apoptosis of human and rabbit pleural mesothelial cells via reactive oxygen speciesQ37361129
Asbestos-related diseasesQ38645466
Thyroid hormone promotes serine phosphorylation of p53 by mitogen-activated protein kinaseQ40819915
Resveratrol-induced activation of p53 and apoptosis is mediated by extracellular-signal-regulated protein kinases and p38 kinaseQ40821365
Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatinQ40859019
DNA breakage in asbestos-treated normal and transformed (TSV40) rat pleural mesothelial cells.Q40882737
ERKs and p38 kinase phosphorylate p53 protein at serine 15 in response to UV radiationQ40883900
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2.Q40911658
Asbestos and DNA double strand breaks.Q40976725
Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicalsQ41362043
Mechanisms of fiber-induced genotoxicityQ41662498
Inhaled asbestos fibers induce p53 expression in the rat lungQ42437265
Screening the p53 status of human cell lines using a yeast functional assayQ42815910
Cadmium induces phosphorylation of p53 at serine 15 in MCF-7 cellsQ43575297
Mechanism of p53-dependent apoptosis induced by 3-methylcholanthrene: involvement of p53 phosphorylation and p38 MAPK.Q43797734
Vitronectin adsorption to chrysotile asbestos increases fiber phagocytosis and toxicity for mesothelial cellsQ46472460
Enhancement of fibrogenesis by the p53 tumor suppressor protein in asbestos-exposed rodentsQ49164232
Asbestos: scientific developments and implications for public policyQ50140438
Asbestos induces apoptosis in human alveolar macrophages.Q50534736
Mineral fibers induce apoptosis in Syrian hamster embryo fibroblasts.Q53466773
The p53-dependent G1 cell cycle checkpoint pathway and ataxia-telangiectasiaQ62746091
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectasbestosQ104085
phosphorylationQ242736
P1104number of pages4
P304page(s)509-512
P577publication date2003-04-01
P1433published inEnvironmental Health PerspectivesQ1345904
P1476titlePhosphorylation of p53 protein in A549 human pulmonary epithelial cells exposed to asbestos fibers
P478volume111