A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries

scientific article

A computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKI669
P3181OpenCitations bibliographic resource ID2496324
P932PMC publication ID1166583
P698PubMed publication ID15990391
P5875ResearchGate publication ID7754436

P2093author name stringMichael J Volles
Peter T Lansbury
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Estimating the diversity of peptide populations from limited sequence dataQ30773311
User-friendly algorithms for estimating completeness and diversity in randomized protein-encoding librariesQ30967215
Randomization of genes by PCR mutagenesisQ33198019
Reducing mutational bias in random protein librariesQ33212875
Biased random mutagenesis of peptides: determination of mutation frequency by computer simulationQ36689241
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Polymerase chain reaction: replication errors and reliability of gene diagnosis.Q40448151
Estimation of the mutation rate during error-prone polymerase chain reactionQ41746533
The polymerase chain reaction and branching processesQ46122303
Spontaneous mutators in bacteria: insights into pathways of mutagenesis and repairQ46617407
A general method for saturation mutagenesis of cloned DNA fragmentsQ48377023
Mutation-replication statistics of polymerase chain reactions.Q52021434
Modeling the polymerase chain reaction.Q52362280
Optimizing nucleotide mixtures to encode specific subsets of amino acids for semi-random mutagenesis.Q52425351
An efficient random mutagenesis technique using anE.coli mutator strainQ54567981
Modeling DNA mutation and recombination for directed evolution experimentsQ56901668
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcomputer programQ40056
P304page(s)3667-3677
P577publication date2005-06-29
P1433published inNucleic Acids ResearchQ135122
P1476titleA computer program for the estimation of protein and nucleic acid sequence diversity in random point mutagenesis libraries
P478volume33

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cites work (P2860)
Q51860998A quantitative approach for polymerase chain reactions based on a hidden Markov model.
Q35652428Biomathematical description of synthetic peptide libraries
Q58022681Challenges of the genetic code for exploring sequence space in directed protein evolution
Q34204232Enhancing the efficiency of directed evolution in focused enzyme libraries by the adaptive substituent reordering algorithm.
Q39784970GLUE-IT and PEDEL-AA: new programmes for analyzing protein diversity in randomized libraries
Q35182675Lessons from diversity of directed evolution experiments by an analysis of 3,000 mutations
Q38017581Molecular engineering of antibodies for therapeutic and diagnostic purposes
Q39871070Mutanalyst, an online tool for assessing the mutational spectrum of epPCR libraries with poor sampling
Q24293089Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity
Q33931885SeSaM-Tv-II generates a protein sequence space that is unobtainable by epPCR.
Q33301937Steering directed protein evolution: strategies to manage combinatorial complexity of mutant libraries

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