CD8 T Cell-Independent Antitumor Response and Its Potential for Treatment of Malignant Gliomas

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CD8 T Cell-Independent Antitumor Response and Its Potential for Treatment of Malignant Gliomas is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/CANCERS8080071
P3181OpenCitations bibliographic resource ID4279289
P932PMC publication ID4999780
P698PubMed publication ID27472363

P50authorThomas S GriffithQ56958439
Katherine A MurphyQ61086767
P2093author name stringThomas S Griffith
Katherine A Murphy
P2860cites workNeutrophil infiltration into human gliomasQ48102911
Growth of P511 mastocytoma cells in BALB/c mouse brain elicits CTL response without tumor elimination: a new tumor model for regional central nervous system immunityQ48632166
A vaccine targeting mutant IDH1 induces antitumour immunityQ48649314
Effects of treatment on long-term survivors with malignant astrocytomasQ48847104
Robust tumor immunity to melanoma mediated by interleukin-9-producing T cellsQ24601213
Adoptive cell transfer: a clinical path to effective cancer immunotherapyQ24644774
Cancer regression and autoimmunity in patients after clonal repopulation with antitumor lymphocytesQ24676216
Current vaccine trials in glioblastoma: a reviewQ26828965
The interaction of anticancer therapies with tumor-associated macrophagesQ27016634
Is the brain "an immunologically privileged site"? 3. Studies based on homologous skin grafts to the brain and subcutaneous tissues.Q51233176
Residual function following hemispherectomy for tumour and for infantile hemiplegia.Q51339551
CpG blocks immunosuppression by myeloid-derived suppressor cells in tumor-bearing miceQ83201956
Structural and functional features of central nervous system lymphatic vesselsQ27316769
Sipuleucel-T immunotherapy for castration-resistant prostate cancerQ27860648
The blockade of immune checkpoints in cancer immunotherapyQ27860852
Improved Survival with Ipilimumab in Patients with Metastatic MelanomaQ27861062
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinationsQ28075712
Myeloid-derived suppressor cells as regulators of the immune systemQ28131637
Autoantibodies against GLEA2 and PHF3 in glioblastoma: tumor-associated autoantibodies correlated with prolonged survivalQ28251910
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trialQ29547224
CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humansQ29614348
Nitric oxide and macrophage functionQ29615327
Malignant gliomas in adultsQ29615708
Chimeric antigen receptor T cells for sustained remissions in leukemiaQ29617588
Polarization of tumor-associated neutrophil phenotype by TGF-beta: "N1" versus "N2" TANQ29619346
CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011.Q30402063
Downregulation of major histocompatibility complex antigens in invading glioma cells: stealth invasion of the brainQ31148056
Role of the cervical lymphatics in the Th2-type hierarchy of CNS immune regulationQ33784134
NK cell-based immunotherapy for malignant diseasesQ33827433
Temozolomide and treatment of malignant glioma.Q33983627
Mast cell accumulation in glioblastoma with a potential role for stem cell factor and chemokine CXCL12.Q34032023
Characterization of cytokine-induced myeloid-derived suppressor cells from normal human peripheral blood mononuclear cellsQ34072679
Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-toleranceQ34111451
Overview of cellular immunotherapy for patients with glioblastoma.Q34189694
The role of MHC class II-restricted tumor antigens and CD4+ T cells in antitumor immunityQ34232543
Durable therapeutic efficacy utilizing combinatorial blockade against IDO, CTLA-4, and PD-L1 in mice with brain tumors.Q34276759
OX40 costimulation can abrogate Foxp3+ regulatory T cell-mediated suppression of antitumor immunityQ34477650
Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed GlioblastomaQ34488771
The B7-CD28 superfamilyQ34575331
The blood-brain barrier and cancer: transporters, treatment, and Trojan horsesQ34577796
Macrophage regulation of tumor responses to anticancer therapiesQ34649588
Induction of CD8+ T-cell responses against novel glioma-associated antigen peptides and clinical activity by vaccinations with {alpha}-type 1 polarized dendritic cells and polyinosinic-polycytidylic acid stabilized by lysine and carboxymethylcelluloQ34666875
Highly activated cytotoxic CD8 T cells express protective IL-10 at the peak of coronavirus-induced encephalitisQ34713380
Gene expression profile correlates with T-cell infiltration and relative survival in glioblastoma patients vaccinated with dendritic cell immunotherapyQ34764143
Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.Q34853757
Mast cells as targets for immunotherapy of solid tumors.Q38201926
Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potentialQ38414485
Glioblastoma Eradication Following Immune Checkpoint Blockade in an Orthotopic, Immunocompetent ModelQ38821358
T cells redirected to EphA2 for the immunotherapy of glioblastomaQ39258646
CD8+ T cell-independent tumor regression induced by Fc-OX40L and therapeutic vaccination in a mouse model of glioma.Q39303777
An in vivo immunotherapy screen of costimulatory molecules identifies Fc-OX40L as a potent reagent for the treatment of established murine gliomasQ39316966
A critical role for mast cells and mast cell-derived IL-6 in TLR2-mediated inhibition of tumor growth.Q39637223
Possible involvement of the M2 anti-inflammatory macrophage phenotype in growth of human gliomas.Q39972447
In vivo vaccination with tumor cell lysate plus CpG oligodeoxynucleotides eradicates murine glioblastomaQ40042353
Dendritic cell vaccination in glioblastoma patients induces systemic and intracranial T-cell responses modulated by the local central nervous system tumor microenvironmentQ40400501
Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic diseaseQ40630247
Normal cerebrospinal fluid suppresses the in vitro development of cytotoxic T cells: role of the brain microenvironment in CNS immune regulationQ41019909
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responsesQ41779891
HER2-specific T cells target primary glioblastoma stem cells and induce regression of autologous experimental tumorsQ41783221
Ovalbumin is more immunogenic when introduced into brain or cerebrospinal fluid than into extracerebral sitesQ42089231
CONDITIONS DETERMINING THE TRANSPLANTABILITY OF TISSUES IN THE BRAIN.Q42787795
Primary T cell expansion and differentiation in vivo requires antigen presentation by B cells.Q43508744
Exploiting the glioblastoma peptidome to discover novel tumour-associated antigens for immunotherapy.Q44783246
Cyclophosphamide promotes chronic inflammation-dependent immunosuppression and prevents antitumor response in melanomaQ45712444
Triggering of OX40 (CD134) on CD4(+)CD25+ T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.Q45879987
NK and CD4 cells collaborate to protect against melanoma tumor formation in the brainQ46126574
Immune cell infiltrate differences in pilocytic astrocytoma and glioblastoma: evidence of distinct immunological microenvironments that reflect tumor biologyQ46175398
Vaccination of malignant glioma patients with peptide-pulsed dendritic cells elicits systemic cytotoxicity and intracranial T-cell infiltrationQ46720423
Trends in central nervous system tumor incidence relative to other common cancers in adults, adolescents, and children in the United States, 2000 to 2010.Q34982039
CSF-1R inhibition alters macrophage polarization and blocks glioma progressionQ34993852
Suppression of human glioma xenografts with second-generation IL13R-specific chimeric antigen receptor-modified T cellsQ35111932
EGFRvIII-specific chimeric antigen receptor T cells migrate to and kill tumor deposits infiltrating the brain parenchyma in an invasive xenograft model of glioblastomaQ35145144
Unarmed, tumor-specific monoclonal antibody effectively treats brain tumorsQ35162055
B cells are critical to T-cell-mediated antitumor immunity induced by a combined immune-stimulatory/conditionally cytotoxic therapy for glioblastoma.Q35444346
CpG-mediated modulation of MDSC contributes to the efficacy of Ad5-TRAIL therapy against renal cell carcinoma.Q35546240
Neutrophils promote the malignant glioma phenotype through S100A4.Q35577475
Intratumoral injection of CpG oligonucleotides induces the differentiation and reduces the immunosuppressive activity of myeloid-derived suppressor cellsQ35740077
Rational development and characterization of humanized anti-EGFR variant III chimeric antigen receptor T cells for glioblastomaQ35741739
Therapeutic targeting of the effector T-cell co-stimulatory molecule OX40.Q35790354
Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastomaQ35815273
CD4 cells can be more efficient at tumor rejection than CD8 cellsQ35839925
Comprehensive analysis of current approaches to inhibit regulatory T cells in cancerQ36057441
Bioactivity and Safety of IL13Rα2-Redirected Chimeric Antigen Receptor CD8+ T Cells in Patients with Recurrent Glioblastoma.Q36248008
Recognition of glioma stem cells by genetically modified T cells targeting EGFRvIII and development of adoptive cell therapy for gliomaQ36321176
Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine, TRAIL.Q36368090
The central role of CD4(+) T cells in the antitumor immune responseQ36401381
Autologous glioma cell vaccine admixed with interleukin-4 gene transfected fibroblasts in the treatment of patients with malignant gliomasQ36478070
Phase I trial of a multi-epitope-pulsed dendritic cell vaccine for patients with newly diagnosed glioblastomaQ36523499
Increased proportion of FoxP3+ regulatory T cells in tumor infiltrating lymphocytes is associated with tumor recurrence and reduced survival in patients with glioblastoma.Q36639475
Multiple HLA class II-restricted melanocyte differentiation antigens are recognized by tumor-infiltrating lymphocytes from a patient with melanomaQ36696205
Stereotactic radiation therapy combined with immunotherapy: augmenting the role of radiation in local and systemic treatmentQ36746004
Chimeric antigen receptor--modified T cells: clinical translation in stem cell transplantation and beyondQ36845643
Diffuse glioma growth: a guerilla warQ36931690
Integrating costimulatory agonists to optimize immune-based cancer therapiesQ37352989
Immune-checkpoint blockade and active immunotherapy for gliomaQ37420586
Late effects of therapy for pediatric brain tumor survivorsQ37617858
Interferon-gamma in brain tumor immunotherapy.Q37640598
Anti-PD-1 blockade and stereotactic radiation produce long-term survival in mice with intracranial gliomasQ37658308
Cytolytic CD4+T cells in viral immunityQ37812127
Tumor-associated neutrophils: new targets for cancer therapyQ37856086
Ipilimumab (Yervoy) and the TGN1412 catastropheQ37912761
Tumor-associated neutrophils: friend or foe?Q37994480
Targeting Tregs in Malignant Brain Cancer: Overcoming IDO.Q38110540
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)71
P577publication date2016-01-01
P1433published inCancersQ27722963
P1476titleCD8 T Cell-Independent Antitumor Response and Its Potential for Treatment of Malignant Gliomas
P478volume8