review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Vasilios Papadopoulos | Q37834601 |
P2093 | author name string | Andrew Midzak | |
P2860 | cites work | Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function | Q24296269 |
Role of steroid 11 beta-hydroxylase and steroid 18-hydroxylase in the biosynthesis of glucocorticoids and mineralocorticoids in humans | Q24301996 | ||
Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system | Q24305250 | ||
Cholesterol binding at the cholesterol recognition/ interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide | Q24546891 | ||
Isolation of the mitochondrial benzodiazepine receptor: association with the voltage-dependent anion channel and the adenine nucleotide carrier | Q24562122 | ||
Supercomplexes in the respiratory chains of yeast and mammalian mitochondria | Q24599994 | ||
σ-1 receptor at the mitochondrial-associated endoplasmic reticulum membrane is responsible for mitochondrial metabolic regulation | Q24610992 | ||
MUSCLE: multiple sequence alignment with high accuracy and high throughput | Q24613456 | ||
The Molecular Biology, Biochemistry, and Physiology of Human Steroidogenesis and Its Disorders | Q24613957 | ||
Cloning of cDNA encoding steroid 11 beta-hydroxylase (P450c11) | Q24634230 | ||
Cholesterol feedback: from Schoenheimer's bottle to Scap's MELADL | Q24652984 | ||
Adrenocortical zonation, renewal, and remodeling | Q26852504 | ||
Where the endoplasmic reticulum and the mitochondrion tie the knot: the mitochondria-associated membrane (MAM) | Q26862963 | ||
Evolutionary origin of the mitochondrial cholesterol transport machinery reveals a universal mechanism of steroid hormone biosynthesis in animals | Q27304618 | ||
The structure of adrenodoxin reductase of mitochondrial P450 systems: electron transfer for steroid biosynthesis | Q27618695 | ||
Solution Structure of the Integral Human Membrane Protein VDAC-1 in Detergent Micelles | Q27651854 | ||
Structure of the human voltage-dependent anion channel | Q27652383 | ||
Structural Basis for Three-step Sequential Catalysis by the Cholesterol Side Chain Cleavage Enzyme CYP11A1 | Q27666316 | ||
Protein structure. Crystal structures of translocator protein (TSPO) and mutant mimic of a human polymorphism | Q27697681 | ||
Activating protein-1 cooperates with steroidogenic factor-1 to regulate 3',5'-cyclic adenosine 5'-monophosphate-dependent human CYP11A1 transcription in vitro and in vivo | Q79545290 | ||
Unique dominant negative mutation in the N-terminal mitochondrial targeting sequence of StAR, causing a variant form of congenital lipoid adrenal hyperplasia | Q85513332 | ||
Catecholaminergic systems in stress: structural and molecular genetic approaches. | Q37431126 | ||
The stoichiometry of the conversion of cholesterol and hydroxycholesterols to pregnenolone (3beta-hydroxypregn-5-en-20-one) catalysed by adrenal cytochrome P-450. | Q37440174 | ||
Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450. | Q37567353 | ||
cAMP post-transcriptionally diminishes the abundance of adrenodoxin reductase mRNA | Q37600094 | ||
Origin and diversification of steroids: co-evolution of enzymes and nuclear receptors. | Q37775129 | ||
Protein-protein interactions. | Q37775638 | ||
VDAC isoforms in mammals | Q37948546 | ||
Voltage-dependant anion channels: novel insights into isoform function through genetic models. | Q37952424 | ||
Heterodox notions on pathways of steroidogenesis | Q38038005 | ||
A brief history of adrenal research: steroidogenesis - the soul of the adrenal | Q38057592 | ||
Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis. | Q38068026 | ||
Functional role of mitochondrial respiratory supercomplexes | Q38163695 | ||
Adrenocortical development, maintenance, and disease. | Q38167455 | ||
DHEA - a precursor of ERβ ligands. | Q38240103 | ||
Voltage-dependent anion channels: the wizard of the mitochondrial outer membrane | Q38242922 | ||
New aspects of electron transfer revealed by the crystal structure of a truncated bovine adrenodoxin, Adx(4-108) | Q27749226 | ||
A Simple, Fast, and Accurate Algorithm to Estimate Large Phylogenies by Maximum Likelihood | Q27861000 | ||
Epithelial sodium transport and its control by aldosterone: the story of our internal environment revisited | Q28083698 | ||
Human genes encoding the voltage-dependent anion channel (VDAC) of the outer mitochondrial membrane: mapping and identification of two new isoforms | Q28115229 | ||
Enigma of the peripheral benzodiazepine receptor | Q28139240 | ||
Peripheral-type benzodiazepine receptor: structure and function of a cholesterol-binding protein in steroid and bile acid biosynthesis | Q28205153 | ||
Binding domain-driven intracellular trafficking of sterols for synthesis of steroid hormones, bile acids and oxysterols | Q28241207 | ||
The Product of the CYP11B2 Gene Is Required for Aldosterone Biosynthesis in the Human Adrenal Cortex | Q28243543 | ||
Transcriptional regulation of steroidogenic genes: STARD1, CYP11A1 and HSD3B | Q28247233 | ||
Translocator protein (18 kD) as target for anxiolytics without benzodiazepine-like side effects | Q28249253 | ||
Phosphorylation of steroidogenic acute regulatory protein (StAR) modulates its steroidogenic activity | Q28257180 | ||
Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta) | Q28261360 | ||
Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones | Q28296995 | ||
Voltage-dependent anion channels are dispensable for mitochondrial-dependent cell death | Q28297152 | ||
The synthesis of aldosterone by the adrenal cortex. Two zones (fasciculata and glomerulosa) possess one enzyme for 11 beta-, 18-hydroxylation, and aldehyde synthesis | Q28298988 | ||
Ubc9 and Protein Inhibitor of Activated STAT 1 Activate Chicken Ovalbumin Upstream Promoter-Transcription Factor I-mediated Human CYP11B2 Gene Transcription | Q28299314 | ||
Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage | Q28304398 | ||
Protein structure. Structure and activity of tryptophan-rich TSPO proteins | Q28492337 | ||
TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control | Q28508394 | ||
P450c11B3 mRNA, transcribed from a third P450c11 gene, is expressed in a tissue-specific, developmentally, and hormonally regulated fashion in the rodent adrenal and encodes a protein with both 11-hydroxylase and 18-hydroxylase activities | Q28564671 | ||
Mitochondrial carnitine palmitoyltransferase 1a (CPT1a) is part of an outer membrane fatty acid transfer complex | Q28567616 | ||
Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently | Q28574337 | ||
Proteomic analysis of the mouse liver mitochondrial inner membrane | Q28587359 | ||
Phospholipid synthesis in a membrane fraction associated with mitochondria | Q28647511 | ||
The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s | Q28710080 | ||
NCBI BLAST: a better web interface | Q29614461 | ||
Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2+ responses | Q29616076 | ||
Toward the molecular structure of the mitochondrial channel, VDAC | Q30195505 | ||
Steroidogenic factor I, a key regulator of steroidogenic enzyme expression, is the mouse homolog of fushi tarazu-factor I. | Q33191449 | ||
The voltage dependent anion channel affects mitochondrial cholesterol distribution and function | Q33292291 | ||
A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis | Q33314909 | ||
Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress | Q36354896 | ||
Compound I is the reactive intermediate in the first monooxygenation step during conversion of cholesterol to pregnenolone by cytochrome P450scc: EPR/ENDOR/cryoreduction/annealing studies | Q36378971 | ||
Complex role of the mitochondrial targeting signal in the function of steroidogenic acute regulatory protein revealed by bacterial artificial chromosome transgenesis in vivo. | Q36512421 | ||
Human cytochromes P450 in health and disease | Q36512912 | ||
Evidence That Compound I Is the Active Species in Both the Hydroxylase and Lyase Steps by Which P450scc Converts Cholesterol to Pregnenolone: EPR/ENDOR/Cryoreduction/Annealing Studies | Q36519325 | ||
Kinetics of integrated electron transfer in the mitochondrial respiratory chain: random collisions vs. solid state electron channeling | Q36621081 | ||
Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187 through independent cis elements | Q36733688 | ||
Differential effects of high and low steroidogenic factor-1 expression on CYP11B2 expression and aldosterone production in adrenocortical cells | Q37125954 | ||
Features and applications of blue-native and clear-native electrophoresis | Q37258525 | ||
Independent elaboration of steroid hormone signaling pathways in metazoans | Q37274419 | ||
The adrenal cortex and life | Q37288990 | ||
Identification of a dynamic mitochondrial protein complex driving cholesterol import, trafficking, and metabolism to steroid hormones | Q33636284 | ||
WT1 maintains adrenal-gonadal primordium identity and marks a population of AGP-like progenitors within the adrenal gland | Q33657296 | ||
In vitro studies on the role of the peripheral-type benzodiazepine receptor in steroidogenesis | Q33694938 | ||
The AAA+ ATPase ATAD3A controls mitochondrial dynamics at the interface of the inner and outer membranes. | Q33769230 | ||
Mitochondrial fusion and ERK activity regulate steroidogenic acute regulatory protein localization in mitochondria | Q33778923 | ||
ATP synthesis, mitochondrial function, and steroid biosynthesis in rodent primary and tumor Leydig cells | Q33791705 | ||
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis | Q33977876 | ||
Complexes of sequential metabolic enzymes | Q34039557 | ||
Liver receptor homologue-1 is expressed in the adrenal and can regulate transcription of 11 beta-hydroxylase | Q34091870 | ||
Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis. | Q34283368 | ||
In vitro reconstitution of a functional peripheral-type benzodiazepine receptor from mouse Leydig tumor cells. | Q34336189 | ||
Mitochondrial fusion is essential for steroid biosynthesis | Q34430176 | ||
Mitochondrial protein import and the genesis of steroidogenic mitochondria | Q34672406 | ||
Positron emission tomography and functional characterization of a complete PBR/TSPO knockout. | Q34677691 | ||
Novel androstenetriol interacts with the mitochondrial translocator protein and controls steroidogenesis | Q34684671 | ||
Reversible compartmentalization of de novo purine biosynthetic complexes in living cells | Q34767701 | ||
Mitochondria-associated endoplasmic reticulum membrane (MAM) regulates steroidogenic activity via steroidogenic acute regulatory protein (StAR)-voltage-dependent anion channel 2 (VDAC2) interaction | Q35048873 | ||
Specific benzodiazepine receptors in rat brain characterized by high-affinity (3H)diazepam binding | Q35050152 | ||
Interactions among cytochromes P450 in microsomal membranes: oligomerization of cytochromes P450 3A4, 3A5, and 2E1 and its functional consequences | Q35055663 | ||
Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface | Q35226850 | ||
Role of Ca(2+)/calmodulin-dependent protein kinase kinase in adrenal aldosterone production | Q35436012 | ||
On the role of organized multienzyme systems in cellular metabolism: a general synthesis | Q35529887 | ||
Induction of androgen formation in the male by a TAT-VDAC1 fusion peptide blocking 14-3-3ɛ protein adaptor and mitochondrial VDAC1 interactions | Q35596551 | ||
Steroidogenesis in MA-10 mouse Leydig cells is altered via fatty acid import into the mitochondria | Q35617487 | ||
Computational modeling and biological validation of novel non-steroidal ligands for the cholesterol recognition/interaction amino acid consensus (CRAC) motif of the mitochondrial translocator protein (TSPO). | Q35621076 | ||
The role of cholesterol in the association of endoplasmic reticulum membranes with mitochondria | Q35676605 | ||
Control of aldosterone secretion: a model for convergence in cellular signaling pathways | Q35715226 | ||
Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation. | Q35740284 | ||
VDAC, the early days | Q35812965 | ||
Steroidogenic acute regulatory protein (StAR) retains activity in the absence of its mitochondrial import sequence: implications for the mechanism of StAR action | Q35926434 | ||
Hormone-induced 14-3-3γ adaptor protein regulates steroidogenic acute regulatory protein activity and steroid biosynthesis in MA-10 Leydig cells | Q35939775 | ||
Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels. | Q36119444 | ||
Mitochondrial contact sites: their role in energy metabolism and apoptosis | Q36329450 | ||
Mapping protein-protein proximity in the purinosome. | Q36332857 | ||
Weaving the web of ER tubules | Q36338179 | ||
Mitochondrial cholesterol: mechanisms of import and effects on mitochondrial function | Q38271508 | ||
Origin of the response to adrenal and sex steroids: Roles of promiscuity and co-evolution of enzymes and steroid receptors | Q38274910 | ||
Sympathoadrenal neural crest cells: the known, unknown and forgotten? | Q38315610 | ||
Coelomic epithelium-derived cells in visceral morphogenesis. | Q38659781 | ||
Genetic disorders of Vitamin D biosynthesis and degradation | Q38802670 | ||
Mitochondria-associated membrane formation in hormone-stimulated Leydig cell steroidogenesis: role of ATAD3. | Q38942320 | ||
Transcriptional regulation of human ferredoxin reductase through an intronic enhancer in steroidogenic cells | Q39045125 | ||
The random collision model and a critical assessment of diffusion and collision in mitochondrial electron transport | Q39505283 | ||
Cytophysiology of the adrenal cortex. | Q39728155 | ||
Respiratory active mitochondrial supercomplexes. | Q39913363 | ||
Protein-protein interactions mediate mitochondrial cholesterol transport and steroid biosynthesis | Q40218346 | ||
Novel Action of Activin and Bone Morphogenetic Protein in Regulating Aldosterone Production by Human Adrenocortical Cells | Q40620933 | ||
Transcriptional regulation of human 11beta-hydroxylase (hCYP11B1). | Q40851803 | ||
Regulation of the human P450scc gene by steroidogenic factor 1 is mediated by CBP/p300. | Q41059110 | ||
Angiotensin II and potassium regulate human CYP11B2 transcription through common cis-elements | Q41114081 | ||
Differential regulation of 11 beta-hydroxylase and aldosterone synthase in human adrenocortical H295R cells | Q41183161 | ||
Construction and function of fusion enzymes of the human cytochrome P450scc system | Q41548290 | ||
Peripheral-type benzodiazepine receptors mediate translocation of cholesterol from outer to inner mitochondrial membranes in adrenocortical cells | Q41721996 | ||
The peripheral-type benzodiazepine receptor is functionally linked to Leydig cell steroidogenesis. | Q41740822 | ||
Steroidogenic activity of StAR requires contact with mitochondrial VDAC1 and phosphate carrier protein. | Q41817663 | ||
On the regulatory importance of 27-hydroxycholesterol in mouse liver. | Q42488700 | ||
Adrenocortical zonation in humans under normal and pathological conditions | Q43143746 | ||
The spontaneous Ala147Thr amino acid substitution within the translocator protein influences pregnenolone production in lymphomonocytes of healthy individuals | Q43257256 | ||
Rapid regulation of steroidogenesis by mitochondrial protein import | Q43447990 | ||
Structural and functional study of reconstituted peripheral benzodiazepine receptor | Q43631731 | ||
Differential regulation of aldosterone synthase and 11beta-hydroxylase transcription by steroidogenic factor-1. | Q43946792 | ||
In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding. | Q44402442 | ||
σ-1 Receptors (σ1Binding Sites) Form Raft-Like Microdomains and Target Lipid Droplets on the Endoplasmic Reticulum: Roles in Endoplasmic Reticulum Lipid Compartmentalization and Export | Q44429451 | ||
The pathophysiology and genetics of congenital lipoid adrenal hyperplasia. | Q45931596 | ||
Silencing the expression of mitochondrial acyl-CoA thioesterase I and acyl-CoA synthetase 4 inhibits hormone-induced steroidogenesis | Q46407806 | ||
Molecular cloning and nucleotide sequence of DNA of mitochondrial cytochrome P-450(11 beta) of bovine adrenal cortex | Q48338969 | ||
Peripheral-type benzodiazepine receptors: autoradiographic localization in whole-body sections of neonatal rats. | Q48494192 | ||
Functional characterization of Fdx1: evidence for an evolutionary relationship between P450-type and ISC-type ferredoxins. | Q53217254 | ||
The interaction domain of the redox protein adrenodoxin is mandatory for binding of the electron acceptor CYP11A1, but is not required for binding of the electron donor adrenodoxin reductase. | Q53658883 | ||
A chimaeric llβ-hydroxylase/aldosterone synthase gene causes glucocorticoid-remediable aldosteronism and human hypertension | Q55671192 | ||
Supercomplexes and subcomplexes of mitochondrial oxidative phosphorylation | Q60694989 | ||
Acute stimulation of steroidogenesis in corpus luteum and adrenal cortex by peptide hormones. Rapid induction of a similar protein in both tissues | Q70137891 | ||
Acute ACTH regulation of adrenal corticosteroid biosynthesis. Rapid accumulation of a phosphoprotein | Q70148135 | ||
Aldosterone synthase cytochrome P-450 expressed in the adrenals of patients with primary aldosteronism | Q70169293 | ||
Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP | Q70185292 | ||
Acute action of choriogonadotropin on Leydig tumor cells: changes in the topography of the mitochondrial peripheral-type benzodiazepine receptor | Q71826291 | ||
Human cultured adrenal fasciculata-reticularis cells are targets for angiotensin-II: effects on cytochrome P450 cholesterol side-chain cleavage, cytochrome P450 17 alpha-hydroxylase, and 3 beta-hydroxysteroid-dehydrogenase messenger ribonucleic acid | Q72404097 | ||
Intracellular movement of cholesterol in rat adrenal cells. Kinetics and effects of inhibitors | Q72862534 | ||
Fluorescence resonance energy transfer analysis of cytochromes P450 2C2 and 2E1 molecular interactions in living cells | Q73435884 | ||
Topological analysis of the peripheral benzodiazepine receptor in yeast mitochondrial membranes supports a five-transmembrane structure | Q74088828 | ||
Recombinant CYP11B genes encode enzymes that can catalyze conversion of 11-deoxycortisol to cortisol, 18-hydroxycortisol, and 18-oxocortisol | Q77549376 | ||
Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern | Q77614441 | ||
Electron microscopic tomography of rat-liver mitochondria and their interaction with the endoplasmic reticulum | Q77893813 | ||
Molecular mechanism for cooperation between Sp1 and steroidogenic factor-1 (SF-1) to regulate bovine CYP11A gene expression | Q78165328 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | mitochondrion | Q39572 |
steroid biosynthetic process | Q14358855 | ||
P304 | page(s) | 106 | |
P577 | publication date | 2016-07-29 | |
P1433 | published in | Frontiers in Endocrinology | Q27723680 |
P1476 | title | Adrenal Mitochondria and Steroidogenesis: From Individual Proteins to Functional Protein Assemblies | |
P478 | volume | 7 |
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