Pre-eclampsia: its pathogenesis and pathophysiolgy

scientific article

Pre-eclampsia: its pathogenesis and pathophysiolgy is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.5830/CVJA-2016-009
P3181OpenCitations bibliographic resource ID4305915
P932PMC publication ID4928171
P698PubMed publication ID27213853

P2093author name stringJ Moodley
P Gathiram
P2860cites workSevere intrauterine growth restriction pregnancies have increased placental endoglin levels: hypoxic regulation via transforming growth factor-beta 3Q24304467
Oxidative stress in preeclampsia and the role of free fetal hemoglobinQ26830141
A leading role for the immune system in the pathophysiology of preeclampsiaQ27003069
Angiotensin receptor agonistic autoantibodies and hypertension: preeclampsia and beyondQ27027039
Hydrogen sulfide is an endogenous modulator of leukocyte-mediated inflammationQ28200154
Soluble endoglin contributes to the pathogenesis of preeclampsiaQ28244053
The vasorelaxant effect of H(2)S as a novel endogenous gaseous K(ATP) channel openerQ28363080
Vascular endothelial growth factor (VEGF) and its receptorsQ29615390
Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsiaQ29615916
Hydrogen sulfide is an endogenous stimulator of angiogenesis.Q30492603
Reversal of gene dysregulation in cultured cytotrophoblasts reveals possible causes of preeclampsiaQ30576991
The change in concentrations of angiogenic and anti-angiogenic factors in maternal plasma between the first and second trimesters in risk assessment for the subsequent development of preeclampsia and small-for-gestational age.Q33755648
Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension arrayQ33761815
Cellular and molecular regulation of spiral artery remodelling: lessons from the cardiovascular fieldQ33901191
Expression of cystathionine β-synthase and cystathionine γ-lyase in human pregnant myometrium and their roles in the control of uterine contractilityQ34008944
Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in PregnancyQ34379583
Latest advances in understanding preeclampsiaQ34425288
Characterisation of syncytiotrophoblast vesicles in normal pregnancy and pre-eclampsia: expression of Flt-1 and endoglinQ34599422
Angiogenic factors and preeclampsiaQ34714082
Differential activation of placental unfolded protein response pathways implies heterogeneity in causation of early- and late-onset pre-eclampsiaQ34777981
Pre-eclampsia: pathophysiology, diagnosis, and managementQ35141777
Trophoblast deportation and the maternal inflammatory response in pre-eclampsiaQ35190881
Th1/Th2 balance in preeclampsiaQ35190885
Subclassification of preeclampsiaQ35196220
Pathogenesis of preeclampsia: the genetic componentQ35607465
Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndromeQ35750283
Angiogenic imbalance in the pathophysiology of preeclampsia: newer insightsQ35941009
The "Great Obstetrical Syndromes" are associated with disorders of deep placentationQ36015615
Recent advances in understanding of preeclampsia.Q36255904
TGF-beta superfamily expression and actions in the endometrium and placenta.Q36555340
Angiotensin II type 1 receptor antibodies and increased angiotensin II sensitivity in pregnant ratsQ36683260
Immunoregulation in normal pregnancy and pre-eclampsia: an overviewQ36684096
Hypoxia and reoxygenation: a possible mechanism for placental oxidative stress in preeclampsiaQ36686796
The role of the immune system in preeclampsiaQ36791219
A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a smaQ36984261
The role of angiogenic, anti-angiogenic and vasoactive factors in pre-eclamptic African women: early- versus late-onset pre-eclampsiaQ37041658
Placental origins of preeclampsia: challenging the current hypothesisQ37079631
A systematic review of endoglin gene expression in preeclampsiaQ37102951
Maternal imbalance between pro-angiogenic and anti-angiogenic factors in HIV-infected women with pre-eclampsiaQ37107851
Altered global gene expression in first trimester placentas of women destined to develop preeclampsiaQ37155561
Pre-eclampsia: the pivotal role of the placenta in its pathophysiology and markers for early detectionQ37362662
Dysregulation of anti-angiogenic agents (sFlt-1, PLGF, and sEndoglin) in preeclampsia--a step forward but not the definitive answerQ37620853
First-trimester assessment of placenta function and the prediction of preeclampsia and intrauterine growth restrictionQ37694427
Preeclampsia: a link between trophoblast dysregulation and an antiangiogenic stateQ37723245
Uterine NK cells: active regulators at the maternal-fetal interface.Q37726609
The role of hypoxia and hypoxia-inducible factor-1alpha in preeclampsia pathogenesisQ38049205
Redefining preeclampsia using placenta-derived biomarkers.Q38086495
Tumor necrosis factor-alpha, interleukin-6, and interleukin-10 levels are altered in preeclampsia: a systematic review and meta-analysis.Q38116097
Preeclampsia and uteroplacental acute atherosis: immune and inflammatory factorsQ38152072
Review: the ADAM metalloproteinases - novel regulators of trophoblast invasion?Q38162651
The renin-angiotensin-aldosterone system in pre-eclampsia: the delicate balance between good and bad.Q38176651
IFPA Senior Award Lecture: making sense of pre-eclampsia - two placental causes of preeclampsia?Q38183247
Beyond pregnancy: modulation of trophoblast invasion and its consequences for fetal growth and long-term children's healthQ38219218
Oxygen and placental development during the first trimester: implications for the pathophysiology of pre-eclampsiaQ38311843
Preeclampsia: an excessive maternal inflammatory response to pregnancyQ40824430
Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurityQ41292409
The renin-angiotensin-aldosterone system in pre-eclampsiaQ41554361
Sildenafil citrate improves fetal outcomes in pregnant, L-NAME treated, Sprague-Dawley ratsQ43207984
Cardioprotective effect of hydrogen sulfide in ischemic reperfusion experimental rats and its influence on expression of survivin geneQ43299185
Longitudinal serum concentrations of placental growth factor: evidence for abnormal placental angiogenesis in pathologic pregnanciesQ43991495
High levels of heat shock protein 70 are associated with pro-inflammatory cytokines and may differentiate early- from late-onset preeclampsiaQ45123899
IL-10, TNF-α & IFN-γ: potential early biomarkers for preeclampsiaQ45197229
Sildenafil citrate decreases sFlt-1 and sEng in pregnant l-NAME treated Sprague-Dawley ratsQ46298778
Severe preeclampsia goes along with a cytokine network disturbance towards a systemic inflammatory stateQ46320511
MicroRNA-376c impairs transforming growth factor-β and nodal signaling to promote trophoblast cell proliferation and invasionQ46320867
Maternal autoantibodies from preeclamptic patients activate angiotensin receptors on human mesangial cells and induce interleukin-6 and plasminogen activator inhibitor-1 secretionQ46344658
Time course of maternal plasma volume and hormonal changes in women with preeclampsia or fetal growth restrictionQ46870238
Circulating angiogenic factors and the risk of preeclampsiaQ47217679
High molecular weight angiotensinogen levels in hypertensive pregnant womenQ47265007
Placental perfusion in normal pregnancy and early and late preeclampsia: a magnetic resonance imaging study.Q50801716
Dysregulation of hydrogen sulfide producing enzyme cystathionine γ-lyase contributes to maternal hypertension and placental abnormalities in preeclampsia.Q50963577
Hydrogen sulfide producing enzymes in pregnancy and preeclampsia.Q53181366
Angiogenic factors in maternal circulation and preeclampsia with or without fetal growth restriction.Q54491741
Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia.Q54570213
Placental stress and pre-eclampsia: a revised view.Q54774592
Prevalence of agonistic autoantibodies against the angiotensin II type 1 receptor and soluble fms-like tyrosine kinase 1 in a gestational age-matched case study.Q54782424
Response to Letter Regarding Article, “Dysregulation of Hydrogen Sulfide (H 2 S) Producing Enzyme Cystathionine γ-lyase (CSE) Contributes to Maternal Hypertension and Placental Abnormalities in Preeclampsia”Q57316857
Plasma soluble vascular endothelial growth factor receptor-1 concentration is elevated prior to the clinical diagnosis of pre-eclampsiaQ58778301
The optimization of a chronic nitric oxide synthase (NOS) inhibition model of pre-eclampsia by evaluating physiological changesQ61808454
Early and Late PreeclampsiaQ61853974
Nitric oxide-mediated vasodilation in human pregnancyQ73281658
Re: "Abortion,changed paternity, and risk of preeclampsia in nulliparous women"Q79171603
Systemic inflammatory priming in normal pregnancy and preeclampsia: the role of circulating syncytiotrophoblast microparticlesQ80178439
P275copyright licenseCreative Commons Attribution 2.5 GenericQ18810333
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpre-eclampsiaQ61335
ischemiaQ188151
pathogenesisQ372016
membrane proteinQ423042
intrauterine growth restrictionQ1671598
cell surface receptorQ2476074
maternal healthQ6786626
enzymeQ8047
vascular endothelial growth factor receptor 1 (VEGFR1)Q24778444
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)71-8
P577publication date2016-01-01
P1433published inCardiovascular Journal of AfricaQ26830987
P1476titlePre-eclampsia: its pathogenesis and pathophysiolgy
P478volume27

Reverse relations

cites work (P2860)
Q92153167A data-driven model to study utero-ovarian blood flow physiology during pregnancy
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Q89800074Analyzing Preeclampsia as the Tip of the Iceberg Represented by Women with Long-Term Cardiovascular Disease, Atherosclerosis, and Inflammation
Q92524380Association between RUNX3 gene polymorphisms in severe preeclampsia and its clinical features
Q64229512Association between polymorphisms in CXCR2 gene and preeclampsia
Q37631028Autonomic imbalance captures maternal and fetal circulatory response to pre-eclampsia
Q37297222Early Prognostic Factors for the Progress of Preeclampsia - Our Experience in the Period 2010-2011.
Q90465595Exploration of the regulation and control mechanisms of miR-145 in trophoblast cell proliferation and invasion
Q99630017Extra Virgin Olive Oil Modulates Vasodilator Enzyme Level by Repairing Angiogenesis Function in Rat Model of Preeclampsia
Q90150015Gastrodin improves preeclampsia-induced cell apoptosis by regulation of TLR4/NF-κB in rats
Q55331790Knockdown of Heparanase Suppresses Invasion of Human Trophoblasts by Activating p38 MAPK Signaling Pathway.
Q90480280Long Non-coding RNA Gas5 Is Associated With Preeclampsia and Regulates Biological Behaviors of Trophoblast via MicroRNA-21
Q36198793Maternal cardiac haemodynamics in severe pre-eclampsia complicated by acute pulmonary oedema: A review
Q48254919Mothers' experiences of having a premature infant due to pre-eclampsia.
Q55265408PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension.
Q99237742Placental Microbial Colonization and Its Association With Pre-eclampsia
Q55689583Placental protein 13: An important biological protein in preeclampsia.
Q51129015Plasma biomarkers for the identification of women at risk for early-onset preeclampsia.
Q47841212Pre-Eclampsia and Eclampsia: An Update on the Pharmacological Treatment Applied in Portugal
Q97546356Recent insights on indirect mechanisms in developmental toxicity of nanomaterials
Q49984490Role of angiogenic factors in the pathogenesis and management of pre-eclampsia
Q33713592Severe preeclampsia and eclampsia: incidence, complications, and perinatal outcomes at a low-resource setting, Mpilo Central Hospital, Bulawayo, Zimbabwe
Q48232820Takayasu arteritis a cause of hypertensive disorder of pregnancy: a case report.
Q92827544The REVAMP study: research exploring various aspects and mechanisms in preeclampsia: study protocol
Q89542793The Role of Uric Acid in Preeclampsia: Is Uric Acid a Causative Factor or a Sign of Preeclampsia?
Q47955968The altered PD-1/PD-L1 pathway delivers the 'one-two punch' effects to promote the Treg/Th17 imbalance in pre-eclampsia
Q92146814The effects of sildenafil in maternal and fetal outcomes in pregnancy: A systematic review and meta-analysis
Q39039141Tumor Necrosis Factor-Alpha and Pregnancy: Focus on Biologics. An Updated and Comprehensive Review
Q64077840Use of antidepressants and anxiolytics in early pregnancy and the risk of preeclampsia and gestational hypertension: a prospective study
Q93108704sFlt-1/PlGF Ratio as a Predictive Marker in Women with Suspected Preeclampsia: An Economic Evaluation from a Swiss Perspective

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