Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010-2015)

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Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010-2015) is …
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P6179Dimensions Publication ID1048846695
P356DOI10.1186/S13287-016-0341-0
P8608Fatcat IDrelease_7x4763za3rcmvkfgytpvrezzpu
P3181OpenCitations bibliographic resource ID1036520
P932PMC publication ID4893234
P698PubMed publication ID27259550

P50authorDwaipayan SenQ52322849
P2093author name stringAbhishek Singh
Aastha Singh
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Inhibition of G9a Histone Methyltransferase Converts Bone Marrow Mesenchymal Stem Cells to Cardiac Competent ProgenitorsQ22306435
Role of PlGF in the intra- and intermolecular cross talk between the VEGF receptors Flt1 and Flk1Q24304277
Heart regenerationQ24562846
G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesisQ24673923
Comparison of proliferative and multilineage differentiation potential of human mesenchymal stem cells derived from umbilical cord and bone marrowQ79856815
In vitro cardiomyogenic differentiation of adult human bone marrow mesenchymal stem cells. The role of 5-azacytidineQ80725072
Cardiac troponinsQ80795598
Cardiovascular regenerative medicine: digging in for the long haulQ80969416
Prospective identification of myogenic endothelial cells in human skeletal muscleQ80982228
Mesenchymal stem cells or cardiac progenitors for cardiac repair? A comparative studyQ82038674
Mesenchymal stem cells modified with stromal cell-derived factor 1 alpha improve cardiac remodeling via paracrine activation of hepatocyte growth factor in a rat model of myocardial infarctionQ82270561
Improvement in cardiac function following transplantation of human umbilical cord matrix-derived mesenchymal cellsQ82515849
[Effect of mesenchymal stem cells on cardiac function and restenosis of injured artery after myocardial infarction]Q82556248
Mesenchymal Stem Cells and Cardiomyocytes Interplay to Prevent Myocardial HypertrophyQ42945928
The use of human mesenchymal stem cells encapsulated in RGD modified alginate microspheres in the repair of myocardial infarction in the rat.Q43010738
Xenografted human amniotic membrane-derived mesenchymal stem cells are immunologically tolerated and transdifferentiated into cardiomyocytesQ43052164
Differential effect of myocardial matrix and integrins on cardiac differentiation of human mesenchymal stem cellsQ43121871
Pharmacological preconditioning of mesenchymal stem cells with trimetazidine (1-[2,3,4-trimethoxybenzyl]piperazine) protects hypoxic cells against oxidative stress and enhances recovery of myocardial function in infarcted heart through Bcl-2 expressQ43141698
Impact of anti-apoptotic and anti-oxidative effects of bone marrow mesenchymal stem cells with transient overexpression of heme oxygenase-1 on myocardial ischemiaQ43162637
Transplantation of mesenchymal stem cells preconditioned with diazoxide, a mitochondrial ATP-sensitive potassium channel opener, promotes repair of myocardial infarction in ratsQ43169916
A suspension induction for myocardial differentiation of rat mesenchymal stem cells on various extracellular matrix proteins.Q43211701
Rosuvastatin enhances the therapeutic efficacy of adipose-derived mesenchymal stem cells for myocardial infarction via PI3K/Akt and MEK/ERK pathwaysQ43606581
Evaluation of an established pericardium patch for delivery of mesenchymal stem cells to cardiac tissueQ43715374
Mesenchymal stem cells overexpressing integrin-linked kinase attenuate cardiac fibroblast proliferation and collagen synthesis through paracrine actionsQ43758357
Comparison of cardiac stem cells and mesenchymal stem cells transplantation on the cardiac electrophysiology in rats with myocardial infarctionQ44069938
Impact of repeated intravenous bone marrow mesenchymal stem cells infusion on myocardial collagen network remodeling in a rat model of doxorubicin-induced dilated cardiomyopathyQ44081103
Localization of mesenchymal stem cells grafted with a hyaluronan-based scaffold in the infarcted heartQ44117813
Early cardiac retention of administered stem cells determines clinical efficacy of cell therapy in patients with dilated cardiomyopathyQ44426139
MiR-499 induces cardiac differentiation of rat mesenchymal stem cells through wnt/β-catenin signaling pathwayQ44504125
Tissue kallikrein-modified mesenchymal stem cells provide enhanced protection against ischemic cardiac injury after myocardial infarctionQ44724431
Comparison of proliferation and differentiation capacity of human adipocyte precursor cells from the omental and subcutaneous adipose tissue depot of obese subjectsQ44887109
Mesenchymal stem cells from adult human bone marrow differentiate into a cardiomyocyte phenotype in vitro.Q44960426
Transplantation of mesenchymal stem cells with self-assembling polypeptide scaffolds is conducive to treating myocardial infarction in ratsQ45207014
Human amniotic mesenchymal cells have some characteristics of cardiomyocytesQ45309359
Activity of mesenchymal stem cells in a nonperfused cardiac explant modelQ45820984
Combination of chemokine and angiogenic factor genes and mesenchymal stem cells could enhance angiogenesis and improve cardiac function after acute myocardial infarction in ratsQ45856161
Amniotic mesenchymal stem cells with robust chemotactic properties are effective in the treatment of a myocardial infarction modelQ46041723
MicroRNA-23a is involved in tumor necrosis factor-α induced apoptosis in mesenchymal stem cells and myocardial infarctionQ46075392
Efficacy of subgroup mouse bone mesenchymal stem cells on mobilizing autologous cardiac stem cells and repairing ischemic myocardial tissueQ46563182
Study on culture and in vitro osteogenesis of blood-derived human mesenchymal stem cellsQ46676512
Trimetazidine induces parkinsonism, gait disorders and tremor.Q46789396
Myocardium-targeted transplantation of mesenchymal stem cells by diagnostic ultrasound-mediated microbubble destruction improves cardiac function in myocardial infarction of New Zealand rabbitsQ47968678
Mesenchymal stem cells enhanced cardiac nerve sprouting via nerve growth factor in a rat model of myocardial infarctionQ48026653
Distinct patterns of histone modifications at cardiac-specific gene promoters between cardiac stem cells and mesenchymal stem cellsQ48033062
Quantifying mesenchymal stem cells in the mononuclear cell fraction of bone marrow samples obtained for cell therapy.Q48093656
Magnetic resonance evaluation of transplanted mesenchymal stem cells after myocardial infarction in swineQ50268532
Ex vivo expansion of human mesenchymal stem cells on microcarriersQ50279611
MicroRNA-34a regulates cardiac ageing and functionQ50320387
Adipose tissue derived mesenchymal stem cells for musculoskeletal repair in veterinary medicineQ26822932
Suicide gene reveals the myocardial neovascularization role of mesenchymal stem cells overexpressing CXCR4 (MSC(CXCR4))Q27316726
Multilineage potential of adult human mesenchymal stem cellsQ27860737
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementQ27861120
Challenges in identifying the best source of stem cells for cardiac regeneration therapyQ28083859
Muscle satellite cellsQ28205273
Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptorsQ28256173
MicroRNA miR-1 is up-regulated in remote myocardium in patients with myocardial infarctionQ28273466
Fat tissue: an underappreciated source of stem cells for biotechnologyQ28298098
miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodelingQ28304542
Over-expression of HO-1 on mesenchymal stem cells promotes angiogenesis and improves myocardial function in infarcted myocardiumQ28576241
Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction modelQ28740879
Vascular endothelial growth factor (VEGF) and its receptorsQ29615390
RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trialQ29620044
The relationship between the spleen colony-forming cell and the haemopoietic stem cellQ29620090
Adult cardiac stem cells are multipotent and support myocardial regenerationQ29620122
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissueQ29620725
Concise review: mesenchymal stem cells: their phenotype, differentiation capacity, immunological features, and potential for homing.Q30157916
Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow.Q30167892
Mesenchymal progenitor cells in human umbilical cord bloodQ30168979
Ultrasound-Targeted Microbubble Destruction Improves the Migration and Homing of Mesenchymal Stem Cells after Myocardial Infarction by Upregulating SDF-1/CXCR4: A Pilot StudyQ30409340
Guided cardiopoiesis enhances therapeutic benefit of bone marrow human mesenchymal stem cells in chronic myocardial infarctionQ30496413
Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiationQ30523741
Cardiac progenitors derived from reprogrammed mesenchymal stem cells contribute to angiomyogenic repair of the infarcted heartQ30528601
MicroRNA-133a engineered mesenchymal stem cells augment cardiac function and cell survival in the infarct heartQ30652787
Autologous transplantation of bone marrow cells improves damaged heart functionQ30815113
[Cardiovascular regenerative medicine at the crossroads. Clinical trials of cellular therapy must now be based on reliable experimental data from animals with characteristics similar to human's].Q31082580
Right into the heart of microRNA-133aQ33346399
MicroRNA-133a protects against myocardial fibrosis and modulates electrical repolarization without affecting hypertrophy in pressure-overloaded adult heartsQ33580704
Combining neuropeptide Y and mesenchymal stem cells reverses remodeling after myocardial infarctionQ33589174
Islet-1 promotes the cardiac-specific differentiation of mesenchymal stem cells through the regulation of histone acetylationQ33608677
An experimental study on rabbit bone marrow mesenchymal stem cells double-labeled by PKH26 and 5-bromo-2'-deoxyuridine in vitro and application in cardiac patchQ33652717
Activated platelets interfere with recruitment of mesenchymal stem cells to apoptotic cardiac cells via high mobility group box 1/Toll-like receptor 4-mediated down-regulation of hepatocyte growth factor receptor METQ33676193
Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cellsQ33746224
Dynamic induction of pro-angiogenic milieu after transplantation of marrow-derived mesenchymal stem cells in experimental myocardial infarction.Q50458643
Bosentan protects the spinal cord from ischemia reperfusion injury in rats through vascular endothelial growth factor receptors.Q50461202
Transplantation of mesenchymal stem cells carrying the human receptor activity-modifying protein 1 gene improves cardiac function and inhibits neointimal proliferation in the carotid angioplasty and myocardial infarction rabbit model.Q50462523
Mesenchymal stem cells induce an inflammatory response after intravenous infusion.Q50478967
Differentiation of adipose tissue-derived mesenchymal stem cells into cardiomyocytes.Q50486992
[Effects of hRAMP1 modified mesenchymal stem cells on restenosis and heart function in rabbit model of carotid angioplasty and myocardial infarction].Q50487876
[Effect of gene modified mesenchymal stem cells overexpression human receptor activity modified protein 1 on inflammation and cardiac repair in a rabbit model of myocardial infarction].Q50488111
Cardiac Repair With a Novel Population of Mesenchymal Stem Cells Resident in the Human Heart.Q50577371
Myocardial structural protein expression in umbilical cord blood mesenchymal stem cells after myogenic induction.Q50753352
Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.Q50790713
bFGF binding cardiac extracellular matrix promotes the repair potential of bone marrow mesenchymal stem cells in a rabbit model for acute myocardial infarction.Q50903293
Myocardin-related transcription factor-A-overexpressing bone marrow stem cells protect cardiomyocytes and alleviate cardiac damage in a rat model of acute myocardial infarction.Q50958017
Allogenic peripheral blood derived mesenchymal stem cells (MSCs) enhance bone regeneration in rabbit ulna critical-sized bone defect model.Q51254265
CXCR4 Antagonist TG-0054 Mobilizes Mesenchymal Stem Cells, Attenuates Inflammation, and Preserves Cardiac Systolic Function in a Porcine Model of Myocardial Infarction.Q51724009
Epicardium-derived cardiac mesenchymal stem cells: expanding the outer limit of heart repair.Q51798304
Regulating myogenic differentiation of mesenchymal stem cells using thermosensitive hydrogels.Q51807649
Nuclear cardiac troponin and tropomyosin are expressed early in cardiac differentiation of rat mesenchymal stem cells.Q51810929
Human Wharton's jelly stem cells have unique transcriptome profiles compared to human embryonic stem cells and other mesenchymal stem cells.Q51812638
Signals through glycoprotein 130 regulate the endothelial differentiation of cardiac stem cells.Q51824234
Direct implantation versus platelet-rich fibrin-embedded adipose-derived mesenchymal stem cells in treating rat acute myocardial infarction.Q53059882
Injection of composite with bone marrow-derived mesenchymal stem cells and a novel synthetic hydrogel after myocardial infarction: a protective role in left ventricle function.Q53061228
Protective effects of Gingko biloba extract 761 on myocardial infarction via improving the viability of implanted mesenchymal stem cells in the rat heart.Q53065864
Cotransplantation of human umbilical cord-derived mesenchymal stem cells and umbilical cord blood-derived CD34⁺ cells in a rabbit model of myocardial infarction.Q53085014
Wharton's jelly-derived mesenchymal stem cells promote myocardial regeneration and cardiac repair after miniswine acute myocardial infarction.Q53096877
In vivo differentiation of human amniotic epithelial cells into cardiomyocyte-like cells and cell transplantation effect on myocardial infarction in rats: comparison with cord blood and adipose tissue-derived mesenchymal stem cells.Q53158324
MicroRNA 16 enhances differentiation of human bone marrow mesenchymal stem cells in a cardiac niche toward myogenic phenotypes in vitro.Q53164011
Cardiac repair achieved by bone marrow mesenchymal stem cells/silk fibroin/hyaluronic acid patches in a rat of myocardial infarction model.Q53169787
[Effect of combined therapy of granulocyte colony stimulating factor and bone marrow mesenchymal stem cells carrying hepatocyte growth factor gene on angiogenesis of myocardial infarction in rats].Q53235120
A natural compound induced cardiogenic differentiation of endogenous MSCs for repair of infarcted heartQ82588048
Tanshinone IIA increases recruitment of bone marrow mesenchymal stem cells to infarct region via up-regulating stromal cell-derived factor-1/CXC chemokine receptor 4 axis in a myocardial ischemia modelQ82830313
Micropatterned matrix directs differentiation of human mesenchymal stem cells towards myocardial lineageQ82903564
miR-499 regulates mitochondrial dynamics by targeting calcineurin and dynamin-related protein-1Q83034995
In vivo therapy of myocardial infarction with mesenchymal stem cells modified with prostaglandin I synthase gene improves cardiac performance in miceQ83160114
TRPC6, a potential novel target for enhancing cardiac repair of bone marrow mesenchymal stem cellsQ83275671
Intracoronary delivery of mesenchymal stem cells reduces proarrhythmogenic risks in swine with myocardial infarctionQ83347349
[Dural modulation effects of mesenchymal stem cells implantation on myocardial collagen remodeling in a rat model of myocardial infarction]Q83414786
Pretreatment of rat bone marrow mesenchymal stem cells with a combination of hypergravity and 5-azacytidine enhances therapeutic efficacy for myocardial infarctionQ83462883
Rationale and design of the Transendocardial Injection of Autologous Human Cells (bone marrow or mesenchymal) in Chronic Ischemic Left Ventricular Dysfunction and Heart Failure Secondary to Myocardial Infarction (TAC-HFT) trial: A randomized, doubleQ83582313
Intramyocardial injections of human mesenchymal stem cells following acute myocardial infarction modulate scar formation and improve left ventricular functionQ83628797
Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarctionQ83653952
Effects of bone marrow mesenchymal stem cells in a rat model of myocardial infarctionQ83748603
Intracoronary mesenchymal stem cells promote postischemic myocardial functional recovery, decrease inflammation, and reduce apoptosis via a signal transducer and activator of transcription 3 mechanismQ84046166
Mesenchymal stem cells attenuate myocardial functional depression and reduce systemic and myocardial inflammation during endotoxemiaQ84141816
Intravenous infusion of mesenchymal stem cells is associated with improved myocardial function during endotoxemiaQ84306542
[Effects of the proliferation state of the endothelial progenitor cells preconditioned with salvianolic acid B and bone marrow mesenchymal stem cells transplanted in acute myocardial infarction rats]Q84331900
Pretreatment of human mesenchymal stem cells with pioglitazone improved efficiency of cardiomyogenic transdifferentiation and cardiac functionQ84511363
Treatment of human mesenchymal stem cells with angiotensin receptor blocker improved efficiency of cardiomyogenic transdifferentiation and improved cardiac function via angiogenesisQ84557382
Promigratory activity of oxytocin on umbilical cord blood-derived mesenchymal stem cellsQ84562408
Stem cells transplantation combined with long-term mechanical circulatory support enhances myocardial viability in end-stage ischemic cardiomyopathyQ84789011
The subpopulation of mesenchymal stem cells that differentiate toward cardiomyocytes is cardiac progenitor cellsQ84857807
Molecular advances shed light on cardiac myosin heavy chain expression in health and diseaseQ84924156
Mesenchymal stem cells stimulate protective genetic reprogramming of injured cardiac ventricular myocytesQ85022401
Transplantation of salvianolic acid B pretreated mesenchymal stem cells improves cardiac function in rats with myocardial infarction through angiogenesis and paracrine mechanismsQ85251939
[Beneficial effects of liver X receptor agonist on adipose-derived mesenchymal stem cells transplantation in mice with myocardial infarction]Q85405094
Intracoronary infusion of encapsulated glucagon-like peptide-1-eluting mesenchymal stem cells preserves left ventricular function in a porcine model of acute myocardial infarctionQ85708969
Cell-based therapies for myocardial repair: emerging role for bone marrow-derived mesenchymal stem cells (MSCs) in the treatment of the chronically injured heartQ85750974
[Mesenchymal stem cells implantation increases the myofibroblasts congregating in infarct region in a rat model of myocardial infarction]Q86015581
Crosstalk of mesenchymal stem cells and macrophages promotes cardiac muscle repairQ86151874
Engraftment patterns of human adult mesenchymal stem cells expose electrotonic and paracrine proarrhythmic mechanisms in myocardial cell culturesQ86159146
A critical challenge: dosage-related efficacy and acute complication intracoronary injection of autologous bone marrow mesenchymal stem cells in acute myocardial infarctionQ86733086
Timing of transplantation of autologous bone marrow derived mesenchymal stem cells for treating myocardial infarctionQ87107690
Macrophages regulate renal fibrosis through modulating TGFβ superfamily signalingQ88080852
Role of WNT/β-catenin signaling in rejuvenating myogenic differentiation of aged mesenchymal stem cells from cardiac patientsQ95423512
Hydrogen peroxide preconditioning enhances the therapeutic efficacy of Wharton's Jelly mesenchymal stem cells after myocardial infarctionQ95430666
Intracoronary infusion of Wharton's jelly-derived mesenchymal stem cells: a novel treatment in patients of acute myocardial infarctionQ95505111
Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in vitro culture and do not exhibit telomere maintenance mechanisms.Q53328521
Peroxisome Proliferator-Activated Receptor Gamma Promotes Mesenchymal Stem Cells to Express Connexin43 via the Inhibition of TGF-β1/Smads Signaling in a Rat Model of Myocardial Infarction.Q53379079
Priming of mesenchymal stem cells with oxytocin enhances the cardiac repair in ischemia/reperfusion injury.Q53407725
Combination of retinoic acid, dimethyl sulfoxide and 5-azacytidine promotes cardiac differentiation of human fetal liver-derived mesenchymal stem cells.Q53469182
Functional integration of quantum dot labeled mesenchymal stem cells in a cardiac microenvironment.Q53478486
Pretreatment of mesenchymal stem cells with angiotensin II enhances paracrine effects, angiogenesis, gap junction formation and therapeutic efficacy for myocardial infarction.Q53542332
Mesenchymal stem cells promote cardiac muscle repair via enhanced neovascularization.Q53585286
Umbilical-cord-blood-derived mesenchymal stem cells seeded onto fibronectin-immobilized polycaprolactone nanofiber improve cardiac function.Q53592436
Cellular repressor of E1A-stimulated gene overexpression in bone mesenchymal stem cells protects against rat myocardial infarction.Q53617595
Co-treating mesenchymal stem cells with IL‑1β and TNF-α increases VCAM-1 expression and improves post-ischemic myocardial function.Q54208177
Mesenchymal stem cells overexpressing integrin-linked kinase attenuate left ventricular remodeling and improve cardiac function after myocardial infarction.Q54329066
Mesenchymal stem cells enhance the differentiation of c-kit+ cardiac stem cells.Q54332276
Transplantation of mesenchymal stem cells preconditioned with hydrogen sulfide enhances repair of myocardial infarction in rats.Q54333103
Effects of mesenchymal stem cells on matrix metalloproteinase synthesis in cardiac fibroblasts.Q54353050
Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model.Q54441341
Mesenchymal stem cells promote matrix metalloproteinase secretion by cardiac fibroblasts and reduce cardiac ventricular fibrosis after myocardial infarction.Q54473910
Pretreating mesenchymal stem cells with interleukin-1β and transforming growth factor-β synergistically increases vascular endothelial growth factor production and improves mesenchymal stem cell-mediated myocardial protection after acute ischemia.Q54549578
Transplantation of induced bone marrow mesenchymal stem cells improves the cardiac function of rabbits with dilated cardiomyopathy via upregulation of vascular endothelial growth factor and its receptors.Q54571678
High-efficiency matrix modulus-induced cardiac differentiation of human mesenchymal stem cells inside a thermosensitive hydrogelQ57218244
Mesenchymal stromal cell therapy for steroid-refractory acute and chronic graft versus host disease: a phase 1 studyQ57254134
A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrowQ57601743
Human mesenchymal stem cells express a myofibroblastic phenotype in vitro: comparison to human cardiac myofibroblastsQ58047134
Differential effect of ischaemic preconditioning on mobilisation and recruitment of haematopoietic and mesenchymal stem cells in porcine myocardial ischaemia-reperfusionQ58109706
Mesenchymal Stem Cells Provide Better Results Than Hematopoietic Precursors for the Treatment of Myocardial InfarctionQ59938198
Hypoxia-Inducible Factor 1 Alpha Contributes to Cardiac Healing in Mesenchymal Stem Cells-Mediated Cardiac RepairQ60394825
Spontaneous Malignant Transformation of Human Mesenchymal Stem Cells Reflects Cross-Contamination: Putting the Research Field on Track - LetterQ61039117
Transplantation of Mesenchymal Stem Cells Exerts a Greater Long-Term Effect than Bone Marrow Mononuclear Cells in a Chronic Myocardial Infarction Model in RatQ62980583
Adult bone marrow is a rich source of human mesenchymal ‘stem’ cells but umbilical cord and mobilized adult blood are notQ73267825
Altered regulation of cardiac muscle contraction by troponin T mutations that cause familial hypertrophic cardiomyopathyQ73316865
Hematopoietic stem cellsQ73977336
Isolation of human mesenchymal stem cells: bone marrow versus umbilical cord bloodQ74622924
Mesenchymal stem cellsQ75301443
Searching for alternative sources of postnatal human mesenchymal stem cells: candidate MSC-like cells from umbilical cordQ78799982
Isolation of multipotent mesenchymal stem cells from umbilical cord bloodQ79202796
Expression of Myocardial Specificity Markers MEF-2C and Cx43 in Rat Bone Marrow-derived Mesenchymal Stem Cells Induced by Electrical Stimulation In VitroQ35815068
Concomitant Retrograde Coronary Venous Infusion of Basic Fibroblast Growth Factor Enhances Engraftment and Differentiation of Bone Marrow Mesenchymal Stem Cells for Cardiac Repair after Myocardial InfarctionQ35824554
Adipose-derived mesenchymal stem cells embedded in platelet-rich fibrin scaffolds promote angiogenesis, preserve heart function, and reduce left ventricular remodeling in rat acute myocardial infarctionQ35826439
Myocardial regeneration strategy using Wharton's jelly mesenchymal stem cells as an off-the-shelf 'unlimited' therapeutic agent: results from the Acute Myocardial Infarction First-in-Man Study.Q35829154
Human mesenchymal stromal cells improve scar thickness without enhancing cardiac function in a chronic ischaemic heart failure modelQ35896781
Cardiac regenerationQ35928368
Intravenous administration of atorvastatin-pretreated mesenchymal stem cells improves cardiac performance after acute myocardial infarction: role of CXCR4.Q35941299
Comparison of adipose tissue- and bone marrow- derived mesenchymal stem cells for alleviating doxorubicin-induced cardiac dysfunction in diabetic ratsQ35987027
Regeneration of the heartQ36038854
Hypoxic preconditioning protects against ischemic brain injuryQ36045209
Spherical bullet formation via E-cadherin promotes therapeutic potency of mesenchymal stem cells derived from human umbilical cord blood for myocardial infarctionQ36085396
Cardiac Stem Cell Hybrids Enhance Myocardial Repair.Q36094922
Myocyte-depleted engineered cardiac tissues support therapeutic potential of mesenchymal stem cellsQ36095590
Stem cells of the alveolar epitheliumQ36197188
Autologous Mesenchymal Stem Cells Show More Benefit on Systolic Function Compared to Bone Marrow Mononuclear Cells in a Porcine Model of Chronic Myocardial InfarctionQ36214819
Isolation and characterisation of mesenchymal stem cells derived from human placenta tissueQ36237933
Effects of Intracoronary Administration of Autologous Adipose Tissue-Derived Stem Cells on Acute Myocardial Infarction in a Porcine ModelQ36240131
Endothelial cells and VEGF in vascular developmentQ36342350
Tailoring material properties of cardiac matrix hydrogels to induce endothelial differentiation of human mesenchymal stem cellsQ36384613
Repairing chronic myocardial infarction with autologous mesenchymal stem cells engineered tissue in rat promotes angiogenesis and limits ventricular remodelingQ36521778
Fetal cardiac mesenchymal stem cells express embryonal markers and exhibit differentiation into cells of all three germ layersQ36568629
Mesenchymal stem cells improve cardiac conduction by upregulation of connexin 43 through paracrine signalingQ36593007
Comparison of allogeneic vs autologous bone marrow–derived mesenchymal stem cells delivered by transendocardial injection in patients with ischemic cardiomyopathy: the POSEIDON randomized trialQ36603453
Enhanced effect of combining human cardiac stem cells and bone marrow mesenchymal stem cells to reduce infarct size and to restore cardiac function after myocardial infarctionQ36630155
A comparison of the efficacy of transplantation of bone marrow-derived mesenchymal stem cells and unrestricted somatic stem cells on outcome after acute myocardial infarctionQ36632891
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionQ36634299
Impaired cardioprotective function of transplantation of mesenchymal stem cells from patients with diabetes mellitus to rats with experimentally induced myocardial infarctionQ36689801
Cord lining-mesenchymal stem cells graft supplemented with an omental flap induces myocardial revascularization and ameliorates cardiac dysfunction in a rat model of chronic ischemic heart failureQ36801683
Monocyte chemotactic protein-1 promotes the myocardial homing of mesenchymal stem cells in dilated cardiomyopathyQ36820558
Increased potency of cardiac stem cells compared with bone marrow mesenchymal stem cells in cardiac repairQ36861491
Priming mesenchymal stem cells boosts stem cell therapy to treat myocardial infarctionQ36881332
Increased expression of pigment epithelium-derived factor in aged mesenchymal stem cells impairs their therapeutic efficacy for attenuating myocardial infarction injuryQ36909590
TGF-beta and BMP7 interactions in tumour progression and bone metastasisQ37002892
The identification of novel targets of miR-16 and characterization of their biological functions in cancer cellsQ37115691
Differentiation potential of multipotent progenitor cells derived from war-traumatized muscle tissueQ37132476
Intramyocardial injection of autologous bone marrow-derived ex vivo expanded mesenchymal stem cells in acute myocardial infarction patients is feasible and safe up to 5 years of follow-upQ37216076
Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimenQ37276182
Repair mechanisms of bone marrow mesenchymal stem cells in myocardial infarctionQ37294044
Human Umbilical Cord Blood for Transplantation Therapy in Myocardial InfarctionQ37353891
Thymosin β4 increases the potency of transplanted mesenchymal stem cells for myocardial repairQ37457917
A randomized, open-label, multicenter trial for the safety and efficacy of adult mesenchymal stem cells after acute myocardial infarctionQ37473636
Mesenchymal stem or stromal cells from amnion and umbilical cord tissue and their potential for clinical applications.Q37512295
The role of hypoxia in bone marrow-derived mesenchymal stem cells: considerations for regenerative medicine approachesQ37583936
Recent progress in percutaneous coronary intervention: evolution of the drug-eluting stents, focus on the XIENCE V drug-eluting stentQ37642556
Cardiac fibroblast-derived 3D extracellular matrix seeded with mesenchymal stem cells as a novel device to transfer cells to the ischemic myocardiumQ37661493
Role of the SDF-1-CXCR4 axis in stem cell-based therapies for ischemic cardiomyopathyQ37687409
Surgical models for cardiac regeneration in neonatal miceQ37688522
Mesenchymal stem cells: a new trend for cell therapyQ37729093
Injectable materials for the treatment of myocardial infarction and heart failure: the promise of decellularized matricesQ37772818
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell NicheQ37777514
The role of microRNA in modulating myocardial ischemia-reperfusion injuryQ37801505
Stromal cell-derived factor-1 (SDF-1): homing factor for engineered regenerative medicine.Q37827159
Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC.Q37875244
SDF-1 in myocardial repairQ38016714
Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysisQ38021450
Current status of myocardial regeneration therapyQ38058287
Function and fate of myofibroblasts after myocardial infarctionQ38085345
JAK-STAT signaling in cardiomyogenesis of cardiac stem cellsQ38140885
Cardiac regeneration: current therapies-future conceptsQ38164335
Hydrogel based injectable scaffolds for cardiac tissue regenerationQ38177131
Umbilical cord-derived mesenchymal stem cells: Their advantages and potential clinical utilityQ38207604
Mesenchymal stem cells for treatment of myocardial infarction.Q38214090
Plasticity of mesenchymal stem cells in immunomodulation: pathological and therapeutic implicationsQ38261365
Common expression of stemness molecular markers and early cardiac transcription factors in human Wharton's jelly-derived mesenchymal stem cells and embryonic stem cellsQ38317834
Stem cells: the generation and maintenance of cellular diversityQ38334445
The potential and challenges of using stem cells for cardiovascular repair and regenerationQ38340609
Primary cardiac sarcomas may develop from resident or bone marrow-derived mesenchymal stem cells: use of immunohistochemistry including CD44 and octamer binding protein 3/4.Q38402248
Superior therapeutic potential of young bone marrow mesenchymal stem cells by direct intramyocardial delivery in aged recipients with acute myocardial infarction: in vitro and in vivo investigation.Q35127582
Downregulation of HDAC1 is involved in the cardiomyocyte differentiation from mesenchymal stem cells in a myocardial microenvironmentQ35137443
Improvement of cardiac function by placenta-derived mesenchymal stem cells does not require permanent engraftment and is independent of the insulin signaling pathwayQ35163294
Mesenchymal stem cells from fetal heart attenuate myocardial injury after infarction: an in vivo serial pinhole gated SPECT-CT study in ratsQ35196281
The Bcl-2-regulated apoptotic pathwayQ35218049
Synergistic effect of angiotensin II on vascular endothelial growth factor-A-mediated differentiation of bone marrow-derived mesenchymal stem cells into endothelial cellsQ35562287
Exosomes Secreted from CXCR4 Overexpressing Mesenchymal Stem Cells Promote Cardioprotection via Akt Signaling Pathway following Myocardial InfarctionQ35621007
5-Azacytidine induces cardiac differentiation of human umbilical cord-derived mesenchymal stem cells by activating extracellular regulated kinaseQ35632731
N-cadherin determines individual variations in the therapeutic efficacy of human umbilical cord blood-derived mesenchymal stem cells in a rat model of myocardial infarctionQ35665230
Plasticity of adult stem cellsQ35684656
Mesenchymal stem cells: clinical applications and biological characterization.Q35686355
Intracoronary infusion of Wharton's jelly-derived mesenchymal stem cells in acute myocardial infarction: double-blind, randomized controlled trialQ35688535
Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic InjuryQ35708579
Exogenous Nkx2.5- or GATA-4-transfected rabbit bone marrow mesenchymal stem cells and myocardial cell co-culture on the treatment of myocardial infarction in rabbitsQ35727809
Atherogenic Cytokines Regulate VEGF-A-Induced Differentiation of Bone Marrow-Derived Mesenchymal Stem Cells into Endothelial CellsQ35729854
Involvement of miR-34c in high glucose-insulted mesenchymal stem cells leads to inefficient therapeutic effect on myocardial infarctionQ35732792
Prostaglandin E₁ protects bone marrow-derived mesenchymal stem cells against serum deprivation-induced apoptosisQ35739823
Engineered myocardial tissues constructed in vivo using cardiomyocyte-like cells derived from bone marrow mesenchymal stem cells in ratsQ35747710
Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiationQ35769073
Dual isotope simultaneous imaging to evaluate the effects of intracoronary bone marrow-derived mesenchymal stem cells on perfusion and metabolism in canines with acute myocardial infarctionQ35802937
Myocardial transfection of hypoxia-inducible factor-1α and co-transplantation of mesenchymal stem cells enhance cardiac repair in rats with experimental myocardial infarctionQ33746524
Mesenchymal stem cells with overexpression of midkine enhance cell survival and attenuate cardiac dysfunction in a rat model of myocardial infarctionQ33746629
Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferationQ33757338
Intra-myocardial delivery of mesenchymal stem cells ameliorates left ventricular and cardiomyocyte contractile dysfunction following myocardial infarctionQ33823473
Isolation of primary and immortalized CD34-hematopoietic and mesenchymal stem cells from various sourcesQ33830884
Elevated miR-499 levels blunt the cardiac stress responseQ33900451
An improved transplantation strategy for mouse mesenchymal stem cells in an acute myocardial infarction modelQ33940671
Postinfarct intramyocardial injection of mesenchymal stem cells pretreated with TGF-alpha improves acute myocardial function.Q33994997
Human embryonic and fetal mesenchymal stem cells differentiate toward three different cardiac lineages in contrast to their adult counterpartsQ34023300
The stimulation of the cardiac differentiation of mesenchymal stem cells in tissue constructs that mimic myocardium structure and biomechanics.Q34077880
The nuclear factor NF-kappaB pathway in inflammationQ34114512
Protective effects of trimetazidine on bone marrow mesenchymal stem cells viability in an ex vivo model of hypoxia and in vivo model of locally myocardial ischemiaQ34142745
Physiological consequences of tropomyosin mutations associated with cardiac and skeletal myopathiesQ34152221
Status of umbilical cord blood transplantation in the year 2001.Q34263277
Mesenchymal stem cellsQ34275859
Activation of host tissue trophic factors through JAK-STAT3 signaling: a mechanism of mesenchymal stem cell-mediated cardiac repairQ34357753
In vivo magnetic resonance imaging tracking of transplanted superparamagnetic iron oxide-labeled bone marrow mesenchymal stem cells in rats with myocardial infarctionQ34540793
Stem cells--a clinical update.Q34565718
Activation of liver X receptor improves viability of adipose-derived mesenchymal stem cells to attenuate myocardial ischemia injury through TLR4/NF-κB and Keap-1/Nrf-2 signaling pathwaysQ34579503
The relative contribution of paracine effect versus direct differentiation on adipose-derived stem cell transplantation mediated cardiac repairQ34634535
Mesenchymal stem cells and inflammatory cardiomyopathy: cardiac homing and beyondQ34635689
Intramyocardial transplantation and tracking of human mesenchymal stem cells in a novel intra-uterine pre-immune fetal sheep myocardial infarction model: a proof of concept studyQ34637607
Mesenchymal stem cell transformation and sarcoma genesisQ34654560
Muscle-derived stem cellsQ34658455
Cardiogel: a nano-matrix scaffold with potential application in cardiac regeneration using mesenchymal stem cellsQ34733499
Hypoxia-inducible vascular endothelial growth factor-engineered mesenchymal stem cells prevent myocardial ischemic injuryQ34757237
Risk factors in the development of stem cell therapyQ34761224
Atorvastatin enhance efficacy of mesenchymal stem cells treatment for swine myocardial infarction via activation of nitric oxide synthase.Q34761461
Percutaneous intramyocardial delivery of mesenchymal stem cells induces superior improvement in regional left ventricular function compared with bone marrow mononuclear cells in porcine myocardial infarcted heartQ34785250
Dual-modal tracking of transplanted mesenchymal stem cells after myocardial infarctionQ34956358
TGF-β-induced IRAK-M expression in tumor-associated macrophages regulates lung tumor growthQ35009619
Hepatocyte growth factor-mediated attraction of mesenchymal stem cells for apoptotic neuronal and cardiomyocytic cellsQ35011205
Malignant tumor formation after transplantation of short-term cultured bone marrow mesenchymal stem cells in experimental myocardial infarction and diabetic neuropathy.Q35030040
Hypoxia-induced pulmonary vascular remodeling requires recruitment of circulating mesenchymal precursors of a monocyte/macrophage lineageQ35087969
Placental-derived stem cells: Culture, differentiation and challengesQ38510227
MicroRNAs as a diagnostic tool for heart failure and atrial fibrillationQ38725132
Growth factors mediated differentiation of mesenchymal stem cells to cardiac polymicrotissue using hanging drop and bioreactor.Q39078463
Bone marrow mesenchymal stem cells improve myocardial function in a swine model of acute myocardial infarctionQ39154134
Mesenchymal stem cells overexpressing GCP-2 improve heart function through enhanced angiogenic properties in a myocardial infarction modelQ39298884
Immortalization of bone marrow-derived porcine mesenchymal stem cells and their differentiation into cells expressing cardiac phenotypic markers.Q39429314
Structural aspects of troponin-tropomyosin regulation of skeletal muscle contractionQ39482040
Human cardiac explant-conditioned medium: soluble factors and cardiomyogenic effect on mesenchymal stem cells.Q39853470
Cardiomyoblast-like cells differentiated from human adipose tissue-derived mesenchymal stem cells improve left ventricular dysfunction and survival in a rat myocardial infarction modelQ39961298
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heartQ40036277
Ca2+ and the contractile proteinsQ40117020
Hypoxic adipose mesenchymal stem cells derived conditioned medium protects myocardial infarct in rat.Q40242692
let-7b suppresses apoptosis and autophagy of human mesenchymal stem cells transplanted into ischemia/reperfusion injured heart 7by targeting caspase-3.Q40618751
Placental Growth Factor Promotes Cardiac Muscle Repair via Enhanced NeovascularizationQ40821869
Preclinical evaluation of the immunomodulatory properties of cardiac adipose tissue progenitor cells using umbilical cord blood mesenchymal stem cells: a direct comparative studyQ41091183
Tissue inhibitor of matrix metalloproteinase-3 or vascular endothelial growth factor transfection of aged human mesenchymal stem cells enhances cell therapy after myocardial infarctionQ41672067
Mesenchymal Progenitor Cells: Tissue Origin, Isolation and CultureQ41899828
Cardiac specific gene expression changes in long term culture of murine mesenchymal stem cellsQ41959817
Myocardial injection with GSK-3β-overexpressing bone marrow-derived mesenchymal stem cells attenuates cardiac dysfunction after myocardial infarction.Q42015303
Functional properties of bone marrow derived multipotent mesenchymal stromal cells are altered in heart failure patients, and could be corrected by adjustment of expansion strategiesQ42017721
In vitro differentiation of bone marrow derived porcine mesenchymal stem cells to endothelial cellsQ42139577
Intramyocardial stem cell injection in patients with ischemic cardiomyopathy: functional recovery and reverse remodelingQ42226249
Ischemic cardiac tissue conditioned media induced differentiation of human mesenchymal stem cells into early stage cardiomyocytes.Q42322591
Effects of scaffold material used in cardiovascular surgery on mesenchymal stem cells and cardiac progenitor cellsQ42408076
Controlled delivery of stromal derived factor-1α from poly lactic-co-glycolic acid core-shell particles to recruit mesenchymal stem cells for cardiac regenerationQ42475997
GMP-adapted overexpression of CXCR4 in human mesenchymal stem cells for cardiac repair.Q42507583
Rationale and design of the Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis in Dilated Cardiomyopathy (the POSEIDON-DCM study): a phase I/II, randomized pilot study of the comparative safety and efficacy of transendocardial injectQ42554253
Induced bone marrow mesenchymal stem cells improve cardiac performance of infarcted rat heartsQ42604737
Biomimetic platforms for human stem cell researchQ42650130
Transplantation of SIRT1-engineered aged mesenchymal stem cells improves cardiac function in a rat myocardial infarction modelQ42672566
The mechanism underlying the differentiation of human umbilical cord-derived mesenchymal stem cells into myocardial cells induced by 5-azacytidineQ42715705
Differentiation of allogeneic mesenchymal stem cells induces immunogenicity and limits their long-term benefits for myocardial repairQ42794686
Nitric oxide releasing hydrogel enhances the therapeutic efficacy of mesenchymal stem cells for myocardial infarctionQ42827144
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcellQ7868
regenerationQ193119
mesenchymal stem cellQ1922379
myocardial infarctionQ12152
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)82
P577publication date2016-06-04
P1433published inStem Cell Research & TherapyQ14390536
P1476titleMesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010-2015)
P478volume7

Reverse relations

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