The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium

scientific article

The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3390/NU8050275
P3181OpenCitations bibliographic resource ID1100707
P932PMC publication ID4882688
P698PubMed publication ID27171110
P5875ResearchGate publication ID302872732

P50authorMonica BenvenutoQ56942302
Gloria TafferaQ89420182
P2093author name stringAndrea Modesti
Laura Masuelli
Roberto Bei
Rosanna Mattera
Maria Gabriella Giganti
Paolo Lido
P2860cites workResveratrol downregulates the constitutional activation of nuclear factor-kappaB in multiple myeloma cells, leading to suppression of proliferation and invasion, arrest of cell cycle, and induction of apoptosisQ40313808
Reactive oxygen species in normal physiology, cell injury and phagocytosisQ40539222
Interleukin-1beta and tumour necrosis factor-alpha promote the transformation of human immortalised mesothelial cells by erioniteQ40544397
Curcumin (Diferuloylmethane) Inhibits Constitutive and IL-6-Inducible STAT3 Phosphorylation in Human Multiple Myeloma CellsQ40633129
The O-2 Generating NADPH Oxidase of Phagocytes: Structure and Methods of DetectionQ41115526
Neutrophil and asbestos fiber-induced cytotoxicity in cultured human mesothelial and bronchial epithelial cellsQ41361940
Cytotoxicity of oxidants and asbestos fibers in cultured human mesothelial cellsQ41491859
Gene-asbestos interaction in malignant pleural mesothelioma susceptibility.Q41616144
EGCG induces human mesothelioma cell death by inducing reactive oxygen species and autophagyQ41815893
Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cellsQ41823787
Synergistic inhibition of mesothelioma cell growth by the combination of clofarabine and resveratrol involves Nrf2 downregulationQ42023819
Effects of epigallocatechin-3-gallate on growth, epidermal growth factor receptor signaling pathways, gene expression, and chemosensitivity in human head and neck squamous cell carcinoma cell lines.Q42514580
Suppression of cyclooxygenase-2 expression of skin fibroblasts by wogonin, a plant flavone from Scutellaria radixQ42820681
A green tea-derived polyphenol, epigallocatechin-3-gallate, inhibits IkappaB kinase activation and IL-8 gene expression in respiratory epitheliumQ44142346
Comparative study of antioxidant properties and cytoprotective activity of flavonoidsQ44526760
Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cellsQ44552569
Intraperitoneal cytokine level in patients with peritoneal surface malignancies. A study of the RENAPE (French Network for Rare Peritoneal Malignancies).Q44649132
Flavonoids such as luteolin, fisetin and apigenin are inhibitors of interleukin-4 and interleukin-13 production by activated human basophils.Q44903540
Modulation of signalling nuclear factor-kappaB activation pathway by polyphenols in human intestinal Caco-2 cellsQ45263083
Daidzein administration in vivo reduces myocardial injury in a rat ischemia/reperfusion model by inhibiting NF-kappaB activationQ46182660
Vitronectin adsorption to chrysotile asbestos increases fiber phagocytosis and toxicity for mesothelial cellsQ46472460
Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma.Q46674573
Resveratrol suppresses IL-6-induced ICAM-1 gene expression in endothelial cells: effects on the inhibition of STAT3 phosphorylationQ46693149
Functional Alteration of Natural Killer Cells and Cytotoxic T Lymphocytes upon Asbestos Exposure and in Malignant Mesothelioma PatientsQ38544787
Pro-oxidant activity of polyphenols and its implication on cancer chemoprevention and chemotherapyQ38553207
Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo.Q38828235
Fruit and vegetable intake and risk of cardiovascular disease in US adults: the first National Health and Nutrition Examination Survey Epidemiologic Follow-up StudyQ38898097
Chronic exposure to asbestos enhances TGF-β1 production in the human adult T cell leukemia virus-immortalized T cell line MT-2.Q38943703
Low PIAS3 expression in malignant mesothelioma is associated with increased STAT3 activation and poor patient survivalQ38965924
Combination of ascorbate/epigallocatechin-3-gallate/gemcitabine synergistically induces cell cycle deregulation and apoptosis in mesothelioma cellsQ39066184
Downregulation of Sp1 is involved in honokiol-induced cell cycle arrest and apoptosis in human malignant pleural mesothelioma cells.Q39176316
Role of transcription factor Sp1 in the quercetin-mediated inhibitory effect on human malignant pleural mesotheliomaQ39306656
Regulated chemokine gene expression in mouse mesothelioma and mesothelial cells: TNF-α upregulates both CC and CXC chemokine genesQ39349099
The flavonoid resveratrol suppresses growth of human malignant pleural mesothelioma cells through direct inhibition of specificity protein 1.Q39354770
Butein impairs the protumorigenic activity of malignant pleural mesothelioma cellsQ39425103
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma.Q39529837
Decreased CXCR3 expression in CD4+ T cells exposed to asbestos or derived from asbestos-exposed patientsQ39584952
Reduction of CXC chemokine receptor 3 in an in vitro model of continuous exposure to asbestos in a human T-cell line, MT-2.Q39621271
Suppression of interleukin 6 and 8 production in head and neck cancer cells with curcumin via inhibition of Ikappa beta kinaseQ39883271
(-)-Epigallocatechin gallate inhibition of osteoclastic differentiation via NF-kappaB.Q39894076
Apigenin blocks lipopolysaccharide-induced lethality in vivo and proinflammatory cytokines expression by inactivating NF-kappaB through the suppression of p65 phosphorylation.Q40056838
The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappaB pathway in Chang Liver cellsQ40191280
Involvement of IL-10 and Bcl-2 in resistance against an asbestos-induced apoptosis of T cellsQ40253864
Inhibition of malignant mesothelioma cell matrix metalloproteinase production and invasion by a novel nutrient mixtureQ40271366
Targeting constitutive and interleukin-6-inducible signal transducers and activators of transcription 3 pathway in head and neck squamous cell carcinoma cells by curcumin (diferuloylmethane).Q40286995
Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responsesQ40304269
A novel synthetic mono-carbonyl analogue of curcumin, A13, exhibits anti-inflammatory effects in vivo by inhibition of inflammatory mediators.Q51031273
Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women.Q51530901
Circulating and tumor-infiltrating myeloid cells predict survival in human pleural mesothelioma.Q53251663
Suppression of inducible cyclooxygenase and inducible nitric oxide synthase by apigenin and related flavonoids in mouse macrophages.Q53418310
Licochalcone A induces apoptosis in malignant pleural mesothelioma through downregulation of Sp1 and subsequent activation of mitochondria-related apoptotic pathway.Q53644819
A phase I trial of intratumoral administration of reovirus in patients with histologically confirmed recurrent malignant gliomas.Q55467147
Isoflavones, lignans and stilbenes - origins, metabolism and potential importance to human healthQ59158187
NLRP3 promotes inflammation-induced skin cancer but is dispensable for asbestos-induced mesotheliomaQ60489318
Impaired Expression and Function of Signaling Pathway Enzymes by Anthocyanins: Role on Cancer Prevention and ProgressionQ61756916
Generation of superoxide (O2-.) from alveolar macrophages exposed to asbestiform and nonfibrous particlesQ70165209
Protective effect of natural flavonoids on rat peritoneal macrophages injury caused by asbestos fibersQ71716400
Alveolar macrophage cytokine and growth factor production in a rat model of crocidolite-induced pulmonary inflammation and fibrosisQ71751895
Patho- and immunobiology of malignant mesothelioma: characterisation of tumour infiltrating leucocytes and cytokine production in a murine modelQ71987841
Inactivation of phospholipase A2 by naturally occurring biflavonoid, ochnaflavoneQ72903708
Prospective study of fruit and vegetable consumption and risk of lung cancer among men and womenQ73191054
Protective effects of green tea catechins against asbestos-induced cell injuryQ73489895
The pathogenesis of mesotheliomaQ79253012
Clinical trial of the intratumoral administration of labeled DC combined with systemic chemotherapy for esophageal cancerQ84464648
Inflammatory Cytokines Contribute to Asbestos-Induced Injury of Mesothelial CellsQ85343240
Anti-inflammatory effects of flavonoids [etc.]Q21342966
Free radicals and antioxidants in normal physiological functions and human diseaseQ21710698
Germline BAP1 mutations predispose to malignant mesotheliomaQ24635326
Immunity, Inflammation, and CancerQ27861048
Asbestos and erionite prime and activate the NLRP3 inflammasome that stimulates autocrine cytokine release in human mesothelial cellsQ28387699
Minimal asbestos exposure in germline BAP1 heterozygous mice is associated with deregulated inflammatory response and increased risk of mesotheliomaQ28389071
Crocidolite activates NF-kappa B and MIP-2 gene expression in rat alveolar epithelial cells. Role of mitochondrial-derived oxidantsQ28390119
Malignant mesothelioma: facts, myths, and hypothesesQ28390539
Reactive oxygen species a double-edged sword for mesotheliomaQ28392665
Asbestos inhalation induces reactive nitrogen species and nitrotyrosine formation in the lungs and pleura of the ratQ28392966
The molecular basis of asbestos induced lung injuryQ28394122
Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesotheliomaQ28397153
Curcumin: a double hit on malignant mesotheliomaQ28397518
Inflammasome Modulation by Chemotherapeutics in Malignant MesotheliomaQ28551670
Oxidative stress, inflammation, and cancer: how are they linked?Q29616835
Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studiesQ29617784
Polyphenols: food sources and bioavailabilityQ29618132
Resveratrol suppresses TNF-induced activation of nuclear transcription factors NF-kappa B, activator protein-1, and apoptosis: potential role of reactive oxygen intermediates and lipid peroxidationQ31393490
Time trend of mesothelioma incidence in the United States and projection of future cases: an update based on SEER data for 1973 through 2005.Q33489828
Intratumoral delivery of recombinant vaccinia virus encoding for ErbB2/Neu inhibits the growth of salivary gland carcinoma cellsQ33645792
Chronic inflammation and cytokines in the tumor microenvironmentQ33678275
COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC functionQ33678308
Drug delivery systems for intraperitoneal therapyQ33787894
Why not treat human cancer with interleukin-1 blockade?Q33833871
Epigallocatechin-3-gallate induces mesothelioma cell death via H2 O2 -dependent T-type Ca2+ channel opening.Q33985960
Programmed necrosis induced by asbestos in human mesothelial cells causes high-mobility group box 1 protein release and resultant inflammation.Q34004850
A Phosphotyrosine Proteomic Screen Identifies Multiple Tyrosine Kinase Signaling Pathways Aberrantly Activated in Malignant MesotheliomaQ34018570
Synergistic anti-cancer effects of resveratrol and chemotherapeutic agent clofarabine against human malignant mesothelioma MSTO-211H cellsQ34034335
Increased levels of C-C chemokine RANTES in asbestos exposed workers and in malignant mesothelioma patients from an hyperendemic area.Q34097257
Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesotheliomaQ34122791
The effects of dietary flavonoids on the regulation of redox inflammatory networks.Q34278356
Cancer gene therapy clinical trials: lessons for the futureQ34447184
Role of flavonoids in oxidative stressQ34564436
p53 suppresses the Nrf2-dependent transcription of antioxidant response genes.Q34578157
Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cellsQ34599430
Kinetics of host cell recruitment during dissemination of diffuse malignant peritoneal mesotheliomaQ34618985
Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cellsQ34653164
Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?Q34751976
Dietary phenolics: chemistry, bioavailability and effects on healthQ34994426
Immunological mechanisms in pleural diseaseQ35093537
Multiple roles of oxidants in the pathogenesis of asbestos-induced diseasesQ35111450
Changing pattern in malignant mesothelioma survivalQ35150628
Intratumoral injection of Clostridium novyi-NT spores induces antitumor responsesQ35446009
In vitro and in vivo antitumoral effects of combinations of polyphenols, or polyphenols and anticancer drugs: perspectives on cancer treatmentQ35722741
Chemokine (C-C motif) ligand 3 detection in the serum of persons exposed to asbestos: A patient-based study.Q35904195
Role of inflammatory mediators in angiogenesis.Q36048112
Cancer cell secretion of the DAMP protein HMGB1 supports progression in malignant mesotheliomaQ36074728
Natural diterpenes from coffee, cafestol and kahweol induce apoptosis through regulation of specificity protein 1 expression in human malignant pleural mesotheliomaQ36200631
Dietary polyphenols and the prevention of diseases.Q36209077
Aspirin delays mesothelioma growth by inhibiting HMGB1-mediated tumor progressionQ36347346
Inflammatory chemokines in cancer growth and progressionQ36410708
Flaxseed lignans enriched in secoisolariciresinol diglucoside prevent acute asbestos-induced peritoneal inflammation in miceQ36557014
Local delivery of recombinant vaccinia virus encoding for neu counteracts growth of mammary tumors more efficiently than systemic delivery in neu transgenic miceQ36580203
Expression of inducible nitric oxide synthase in healthy pleura and in malignant mesotheliomaQ36642288
Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605).Q36743579
Inflammation-Related IL1β/IL1R Signaling Promotes the Development of Asbestos-Induced Malignant MesotheliomaQ36863203
HMGB1 and Its Hyperacetylated Isoform are Sensitive and Specific Serum Biomarkers to Detect Asbestos Exposure and to Identify Mesothelioma Patients.Q36901529
Immunological effects of silica and asbestos.Q36926028
Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production.Q36936364
The inflammasome: a danger sensing complex triggering innate immunityQ36989115
Polyphenols, intracellular signalling and inflammation.Q37061789
Translocation pathways for inhaled asbestos fibers.Q37064532
Modulation of immune function by polyphenols: possible contribution of epigenetic factorsQ37083753
Pathophysiology of the pleuraQ37106987
Cancer related inflammation: the macrophage connectionQ37151493
Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cellsQ37207000
Hesperidin Induces Apoptosis by Inhibiting Sp1 and Its Regulatory Protein in MSTO-211H CellsQ37224560
Curcumin suppresses growth of mesothelioma cells in vitro and in vivo, in part, by stimulating apoptosisQ37259632
Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-alpha and matrix metalloproteinase-13 in human chondrocytesQ37270775
The association and nuclear translocation of the PIAS3-STAT3 complex is ligand and time dependentQ37438034
Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease.Q37453072
Flavonoids as anti-inflammatory agents.Q37766941
Microbial and host cells acquire enhanced oxidant-scavenging abilities by binding polyphenolsQ37809889
Effects of flavonoids and other polyphenols on inflammationQ37856995
Dietary flavonoids: molecular mechanisms of action as anti- inflammatory agents.Q37914218
Caspase-1-induced pyroptotic cell deathQ37925075
Immunomodulation and anti-inflammatory roles of polyphenols as anticancer agents.Q37980226
Immunity and malignant mesothelioma: from mesothelial cell damage to tumor development and immune response-based therapies.Q37991095
Inflammasomes in carcinogenesis and anticancer immune responsesQ37995072
Malignant pleural mesothelioma: from the bench to the bedside.Q38019747
Malignant mesothelioma: new insights into a rare diseaseQ38070462
Inhibition of ErbB receptors, Hedgehog and NF-kappaB signaling by polyphenols in cancer.Q38113006
Inflammasome: cancer's friend or foe?Q38187222
Recent developments in delivery, bioavailability, absorption and metabolism of curcumin: the golden pigment from golden spiceQ38187406
Dietary factors affecting polyphenol bioavailabilityQ38211784
TGFβ: A player on multiple fronts in the tumor microenvironment.Q38241602
Sp1 and the 'hallmarks of cancer'.Q38267908
Resveratrol contributes to chemosensitivity of malignant mesothelioma cells with activation of p53.Q38311178
Malignant mesothelioma as an oxidative stress-induced cancer: An updateQ38481011
Curcumin inhibits immunostimulatory function of dendritic cells: MAPKs and translocation of NF-kappa B as potential targetsQ38513973
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
lung neoplasmQ15124212
asbestosQ104085
polyphenolQ290439
mesotheliomaQ1077603
carcinogenesisQ1637543
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)275
P577publication date2016-05-09
P1433published inNutrientsQ7070485
P1476titleThe Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium
P478volume8

Reverse relations

cites work (P2860)
Q38743654(±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice
Q33798391Curcumin blocks autophagy and activates apoptosis of malignant mesothelioma cell lines and increases the survival of mice intraperitoneally transplanted with a malignant mesothelioma cell line.
Q59128240Effect of the BH3 Mimetic Polyphenol (-)-Gossypol (AT-101) on the and Growth of Malignant Mesothelioma
Q33749642Effects of Polyphenols on Oxidative Stress-Mediated Injury in Cardiomyocytes.
Q41340663Evaluation of intracavitary administration of curcumin for the treatment of sarcomatoid mesothelioma
Q33810593In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma
Q42531447Malignant Mesothelioma and Delivery of Polyphenols
Q99414253Polyphenol-Mediated Autophagy in Cancer: Evidence of In Vitro and In Vivo Studies
Q38921007Polyphenol-rich food general and on pregnancy effects: a review
Q64069620Polyphenols as Immunomodulatory Compounds in the Tumor Microenvironment: Friends or Foes?
Q28066929Promiscuous Effects of Some Phenolic Natural Products on Inflammation at Least in Part Arise from Their Ability to Modulate the Expression of Global Regulators, Namely microRNAs

Search more.