Retargeting Strategies for Oncolytic Herpes Simplex Viruses

scientific article

Retargeting Strategies for Oncolytic Herpes Simplex Viruses is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/V8030063
P932PMC publication ID4810253
P698PubMed publication ID26927159
P5875ResearchGate publication ID296634956

P50authorElisa AvitabileQ124273094
Gabriella Campadelli-FiumeQ21062117
Costanza CasiraghiQ56922647
Valerio LeoniQ57015112
Valentina GattaQ57123026
Tatiana GianniQ57126184
Biljana PetrovicQ57314115
P2860cites workPhase II clinical trial of a granulocyte-macrophage colony-stimulating factor-encoding, second-generation oncolytic herpesvirus in patients with unresectable metastatic melanomaQ84834335
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Structure of Herpes Simplex Virus Glycoprotein D Bound to the Human Receptor Nectin-1Q27674775
A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entryQ28145858
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Phase Ib trial of mutant herpes simplex virus G207 inoculated pre-and post-tumor resection for recurrent GBMQ33712977
A herpes oncolytic virus can be delivered via the vasculature to produce biologic changes in human colorectal cancerQ33713249
Recombinant herpes simplex virus type 1 engineered for targeted binding to erythropoietin receptor-bearing cells.Q33786002
The pro-fusion domain of herpes simplex virus glycoprotein D (gD) interacts with the gD N terminus and is displaced by soluble forms of viral receptorsQ33879094
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Structure of unliganded HSV gD reveals a mechanism for receptor-mediated activation of virus entry.Q34324896
Engineered herpes simplex virus 1 is dependent on IL13Ralpha 2 receptor for cell entry and independent of glycoprotein D receptor interactionQ34381483
Treatment of intracranial gliomas in immunocompetent mice using herpes simplex viruses that express murine interleukinsQ34463480
Talimogene Laherparepvec Improves Durable Response Rate in Patients With Advanced MelanomaQ34478015
Carrier cell-based delivery of replication-competent HSV-1 mutants enhances antitumor effect for ovarian cancerQ34512446
Preclinical therapy of disseminated HER-2⁺ ovarian and breast carcinomas with a HER-2-retargeted oncolytic herpesvirus.Q34574879
A phase I study of OncoVEXGM-CSF, a second-generation oncolytic herpes simplex virus expressing granulocyte macrophage colony-stimulating factor.Q34583808
Construction and properties of a herpes simplex virus 1 designed to enter cells solely via the IL-13alpha2 receptorQ34600345
A herpes simplex virus recombinant that exhibits a single-chain antibody to HER2/neu enters cells through the mammary tumor receptor, independently of the gD receptorsQ34648103
Potential for efficacy of the oncolytic Herpes simplex virus 1716 in patients with oral squamous cell carcinomaQ34794313
Structure-function analysis of herpes simplex virus type 1 gD and gH-gL: clues from gDgH chimerasQ35020198
Directing systemic oncolytic viral delivery to tumors via carrier cellsQ35029126
Engineered herpes simplex virus expressing IL-12 in the treatment of experimental murine brain tumorsQ35051285
Molecular gymnastics at the herpesvirus surfaceQ35102490
Use of miRNA response sequences to block off-target replication and increase the safety of an unattenuated, glioblastoma-targeted oncolytic HSVQ35591421
Cytokine conditioning enhances systemic delivery and therapy of an oncolytic virusQ35596563
Fusing structure and function: a structural view of the herpesvirus entry machineryQ35622700
The Engineering of a Novel Ligand in gH Confers to HSV an Expanded Tropism Independent of gD Activation by Its ReceptorsQ35638350
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Potent systemic antitumor activity from an oncolytic herpes simplex virus of syncytial phenotype.Q45732876
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In situ cancer vaccination: an IL-12 defective vector/replication-competent herpes simplex virus combination induces local and systemic antitumor activityQ45756276
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Vitamin D3-inducible mesenchymal stem cell-based delivery of conditionally replicating adenoviruses effectively targets renal cell carcinoma and inhibits tumor growthQ64379255
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Dissociation of HSV gL from gH by αvβ6- or αvβ8-integrin promotes gH activation and virus entryQ35895648
Replication-competent herpes simplex virus retargeted to HER2 as therapy for high-grade gliomaQ35939421
Pediatric cancer gone viral. Part I: strategies for utilizing oncolytic herpes simplex virus-1 in children.Q36109704
Systemic delivery of HER2-retargeted oncolytic-HSV by mesenchymal stromal cells protects from lung and brain metastasesQ36544212
Regulation of herpes simplex virus gB-induced cell-cell fusion by mutant forms of gH/gL in the absence of gD and cellular receptorsQ36647949
Effective treatment of an orthotopic xenograft model of human glioblastoma using an EGFR-retargeted oncolytic herpes simplex virusQ36659325
The multipartite system that mediates entry of herpes simplex virus into the cellQ36851086
Clinical Significance of HER-2 Splice Variants in Breast Cancer Progression and Drug Resistance.Q37019041
Cell carriers to deliver oncolytic viruses to sites of myeloma tumor growthQ37115384
Comparison of intravenous versus intraperitoneal administration of oncolytic herpes simplex virus 1 for peritoneal carcinomatosis in miceQ37132189
Reprogrammed viruses as cancer therapeutics: targeted, armed and shieldedQ37191007
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Cell carriers for oncolytic viruses: Fed Ex for cancer therapyQ37582184
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From virotherapy to oncolytic immunotherapy: where are we now?Q38539862
Engineered adenoviruses combine enhanced oncolysis with improved virus production by mesenchymal stromal carrier cellsQ38918317
DARPin-targeting of measles virus: unique bispecificity, effective oncolysis, and enhanced safetyQ39199726
Oncolytic herpes simplex virus treatment of metastatic breast cancerQ39438675
Glycoprotein gL-independent infectivity of pseudorabies virus is mediated by a gD-gH fusion proteinQ39549912
Development of an oncolytic herpes simplex virus using a tumor-specific HIF-responsive promoterQ39646942
Transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 for targeting prostate tumorsQ39735950
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck.Q39852211
Construction of a fully retargeted herpes simplex virus 1 recombinant capable of entering cells solely via human epidermal growth factor receptor 2.Q39953338
PEGylation and multimerization of the anti-p185HER-2 single chain Fv fragment 4D5: effects on tumor targetingQ40233745
Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashi1 promoter retargeting of gamma34.5-mediated virulence.Q40373406
The herpes simplex virus JMP mutant enters receptor-negative J cells through a novel pathway independent of the known receptors nectin1, HveA, and nectin2.Q40567844
Stem cells loaded with multimechanistic oncolytic herpes simplex virus variants for brain tumor therapy.Q42218017
Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunityQ42248592
Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein H.Q42736704
Novel tumour-specific promoters for transcriptional targeting of hepatocellular carcinoma by herpes simplex virus vectorsQ42793390
Pilot study of oncolytic viral therapy using mutant herpes simplex virus (HF10) against recurrent metastatic breast cancerQ43537822
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in cultureQ44460699
Intralesional injection of herpes simplex virus 1716 in metastatic melanomaQ44718611
Phase I, open-label, dose-escalating study of a genetically engineered herpes simplex virus, NV1020, in subjects with metastatic colorectal carcinoma to the liverQ45289528
A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancerQ45371067
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectviral structural proteinQ7933613
Erb-b2 receptor tyrosine kinase 2Q415271
SimplexvirusQ1509095
oncolytic virusQ1560099
viral tropismQ59717570
virus receptorsQ66053321
P304page(s)63
P577publication date2016-02-26
2016-03-01
P1433published inVirusesQ7935305
P1476titleRetargeting Strategies for Oncolytic Herpes Simplex Viruses
P478volume8