Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians

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Current therapeutic strategies for advanced pancreatic cancer: A review for clinicians is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.5306/WJCO.V7.I1.27
P932PMC publication ID4734936
P698PubMed publication ID26862489
P5875ResearchGate publication ID292386599

P2093author name stringNadia Birocco
Libero Ciuffreda
Isabella Chiappino
Maria Antonietta Satolli
Rosella Spadi
Agostino Ponzetti
Federica Brusa
P2860cites work5-Fluorouracil/leucovorin combined with irinotecan and oxaliplatin (FOLFIRINOX) as second-line chemotherapy in patients with advanced pancreatic cancer who have progressed on gemcitabine-based therapyQ44177883
Long-term outcomes of neoadjuvant chemotherapy before chemoradiation for locally advanced pancreatic cancerQ44650366
FOLFIRINOX for locally advanced pancreatic adenocarcinoma: results of an AGEO multicenter prospective observational cohort.Q44677340
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Phase III trial comparing intensive induction chemoradiotherapy (60 Gy, infusional 5-FU and intermittent cisplatin) followed by maintenance gemcitabine with gemcitabine alone for locally advanced unresectable pancreatic cancer. Definitive results ofQ46604466
Full-dose gemcitabine with concurrent radiation therapy in patients with nonmetastatic pancreatic cancer: a multicenter phase II trialQ46748088
Percutaneous irreversible electroporation for downstaging and control of unresectable pancreatic adenocarcinomaQ48113129
Second-line oxaliplatin, folinic acid, and fluorouracil versus folinic acid and fluorouracil alone for gemcitabine-refractory pancreatic cancer: outcomes from the CONKO-003 trial.Q52875756
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FOLFIRI as second-line chemotherapy for advanced pancreatic cancer: a GISCAD multicenter phase II studyQ57758065
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Microwave Ablation of Pancreatic Head Cancer: Safety and EfficacyQ57998653
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Gemcitabine in the chemoradiotherapy for locally advanced pancreatic cancer: a meta-analysisQ84100587
5-fluorouracil/leucovorin combined with irinotecan and oxaliplatin (FOLFIRINOX) as second-line chemotherapy in patients with metastatic pancreatic adenocarcinomaQ84583196
Unresectable locally advanced pancreatic cancer: treatment with neoadjuvant leucovorin, fluorouracil, irinotecan, and oxaliplatin and assessment of surgical resectabilityQ85646726
Neoadjuvant gemcitabine, docetaxel, and capecitabine followed by gemcitabine and capecitabine/radiation therapy and surgery in locally advanced, unresectable pancreatic adenocarcinomaQ86226098
Preoperative/neoadjuvant therapy in pancreatic cancer: a systematic review and meta-analysis of response and resection percentagesQ21092323
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Chemotherapy and radiotherapy for inoperable advanced pancreatic cancerQ24245085
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Core signaling pathways in human pancreatic cancers revealed by global genomic analysesQ24606006
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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion SequencingQ27860948
New challenges in perioperative management of pancreatic cancerQ28082422
Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancerQ29547558
Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trialQ29547565
FOLFIRINOX versus gemcitabine for metastatic pancreatic cancerQ29547638
Detection of circulating tumor DNA in early- and late-stage human malignanciesQ29615778
Pancreatic cancerQ29616288
Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabineQ29616728
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: a phase III trial of the National Cancer Institute of Canada Clinical Trials GroupQ29619344
High intensity focused ultrasound: a noninvasive therapy for locally advanced pancreatic cancerQ30423784
Safety trial of high-intensity focused ultrasound therapy for pancreatic cancerQ30434098
Preoperative capecitabine and concurrent radiation for borderline resectable pancreatic cancerQ30452636
Concurrent chemoradiotherapy treatment of locally advanced pancreatic cancer: gemcitabine versus 5-fluorouracil, a randomized controlled studyQ33349410
Phase III trial of gemcitabine plus tipifarnib compared with gemcitabine plus placebo in advanced pancreatic cancerQ33360410
A phase III trial of pemetrexed plus gemcitabine versus gemcitabine in patients with unresectable or metastatic pancreatic cancerQ33367733
A prospective randomised phase-II trial with gemcitabine versus gemcitabine plus sunitinib in advanced pancreatic cancer: a study of the CESAR Central European Society for Anticancer Drug Research-EWIV.Q41743831
Protracted venous infusion 5-fluorouracil with concomitant radiotherapy compared with bolus 5-fluorouracil for unresectable pancreatic cancerQ43586373
Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 studyQ43679835
Is the therapeutic index better with gemcitabine-based chemoradiation than with 5-fluorouracil-based chemoradiation in locally advanced pancreatic cancer?Q43960823
Dose-intense PEFG (cisplatin, epirubicin, 5-fluorouracil, gemcitabine) in advanced pancreatic adenocarcinomaQ33371777
The gemcitabine, docetaxel, and capecitabine (GTX) regimen for metastatic pancreatic cancer: a retrospective analysisQ33374920
Phase III, randomized study of gemcitabine and oxaliplatin versus gemcitabine (fixed-dose rate infusion) compared with gemcitabine (30-minute infusion) in patients with pancreatic carcinoma E6201: a trial of the Eastern Cooperative Oncology GroupQ33385281
A randomized phase II trial of two different 4-drug combinations in advanced pancreatic adenocarcinoma: cisplatin, capecitabine, gemcitabine plus either epirubicin or docetaxel (PEXG or PDXG regimen).Q33395577
Dual blockade of epidermal growth factor receptor and insulin-like growth factor receptor-1 signaling in metastatic pancreatic cancer: phase Ib and randomized phase II trial of gemcitabine, erlotinib, and cixutumumab versus gemcitabine plus erlotiniQ33416585
Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studiesQ33632628
FOLFOX as second-line chemotherapy in patients with pretreated metastatic pancreatic cancer from the FIRGEM studyQ33823212
Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancerQ34008107
Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergroup trial S0205Q34049250
Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).Q34049260
Family history of cancer and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Cohort Consortium (PanScan).Q34080597
Pancreatic cancer risk and ABO blood group alleles: results from the pancreatic cancer cohort consortiumQ34094983
Irreversible electroporation in locally advanced pancreatic cancer: potential improved overall survivalQ34310131
Genome-wide association study identifies multiple susceptibility loci for pancreatic cancerQ34314018
Effect of initiating a multidisciplinary care clinic on access and time to treatment in patients with pancreatic adenocarcinomaQ34335066
Regional intra-arterial vs. systemic chemotherapy for advanced pancreatic cancer: a systematic review and meta-analysis of randomized controlled trialsQ34345296
Neoadjuvant treatment of borderline resectable and non-resectable pancreatic cancerQ34357427
S-1 in the treatment of pancreatic cancerQ34467156
Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rateQ34550827
Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial.Q34557866
Phase 2 trial of oxaliplatin plus capecitabine (XELOX) as second-line therapy for patients with advanced pancreatic cancerQ34596369
Phase III randomized comparison of gemcitabine versus gemcitabine plus capecitabine in patients with advanced pancreatic cancerQ34613161
Randomized phase III trial of gemcitabine plus cisplatin compared with single-agent gemcitabine as first-line treatment of patients with advanced pancreatic cancer: the GIP-1 studyQ34617300
Best supportive care (BSC) versus oxaliplatin, folinic acid and 5-fluorouracil (OFF) plus BSC in patients for second-line advanced pancreatic cancer: a phase III-study from the German CONKO-study groupQ34629100
A multicenter analysis of GTX chemotherapy in patients with locally advanced and metastatic pancreatic adenocarcinomaQ34631279
Impact of FOLFIRINOX compared with gemcitabine on quality of life in patients with metastatic pancreatic cancer: results from the PRODIGE 4/ACCORD 11 randomized trialQ34646032
Neoadjuvant FOLFIRINOX for borderline resectable pancreas cancer: a new treatment paradigm?Q34659974
Helicobacter pylori and pancreatic diseasesQ34666355
Risk factors for pancreatic cancer: a summary review of meta-analytical studiesQ34667061
Radiofrequency ablation for unresectable locally advanced pancreatic cancer: a systematic reviewQ34677746
Phase I/II study of verteporfin photodynamic therapy in locally advanced pancreatic cancer.Q35102975
Systematic review of novel ablative methods in locally advanced pancreatic cancer.Q35113615
Advanced pancreatic adenocarcinoma: a review of current treatment strategies and developing therapiesQ35136815
Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancerQ35147520
Phase 2 multi-institutional trial evaluating gemcitabine and stereotactic body radiotherapy for patients with locally advanced unresectable pancreatic adenocarcinomaQ35202400
Combined MEK and PI3K inhibition in a mouse model of pancreatic cancerQ35659511
The Role of Stereotactic Body Radiation Therapy for Pancreatic Cancer: A Single-Institution ExperienceQ35695811
Multicentre phase II trial of trastuzumab and capecitabine in patients with HER2 overexpressing metastatic pancreatic cancerQ35832274
A Systematic Review of the Burden of Pancreatic Cancer in Europe: Real-World Impact on Survival, Quality of Life and Costs.Q35901707
Whole genomes redefine the mutational landscape of pancreatic cancerQ35911034
Neoadjuvant GTX chemotherapy and IMRT-based chemoradiation for borderline resectable pancreatic cancerQ35944817
Expanding surgical treatment of pancreatic cancer: the role of regional chemotherapyQ36033068
FOLFIRI regimen in metastatic pancreatic adenocarcinoma resistant to gemcitabine and platinum-saltsQ36214563
Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trialQ36476666
Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancerQ36550798
A multicenter phase III trial comparing irinotecan-gemcitabine (IG) with gemcitabine (G) monotherapy as first-line treatment in patients with locally advanced or metastatic pancreatic cancerQ36612255
Radiofrequency ablation combined with palliative surgery may prolong survival of patients with advanced cancer of the pancreasQ36646900
Randomized phase III multi-institutional study of TNFerade biologic with fluorouracil and radiotherapy for locally advanced pancreatic cancer: final resultsQ36764997
Allergies and risk of pancreatic cancer: a pooled analysis from the Pancreatic Cancer Case-Control ConsortiumQ37127919
Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines.Q37252144
A randomised phase II study of modified FOLFIRI.3 vs modified FOLFOX as second-line therapy in patients with gemcitabine-refractory advanced pancreatic cancerQ37424087
Inflammation and pancreatic cancer: an evidence-based reviewQ37546454
Pancreatic cancer stroma: understanding biology leads to new therapeutic strategiesQ37617957
Focal cystic pancreatic lesions: assessing variation in radiologists' management recommendationsQ37835584
Insulin resistance and cancer: epidemiological evidenceQ38031219
Insights into the epigenetic mechanisms controlling pancreatic carcinogenesisQ38052795
Alleviating visceral cancer pain in patients with pancreatic cancer using cryoablation and celiac plexus blockQ38069860
Biology and clinical applications of pancreatic cancer stem cellsQ38102108
Stereotactic body radiotherapy in the treatment of pancreatic cancerQ38196488
Systematic review of innovative ablative therapies for the treatment of locally advanced pancreatic cancerQ38294104
The role of radiation therapy in pancreatic ductal adenocarcinoma in the neoadjuvant and adjuvant settingsQ38366159
Stage III pancreatic cancer and the role of irreversible electroporationQ38383285
Pancreatic cancer: from state-of-the-art treatments to promising novel therapiesQ38396634
Cystic tumors of the pancreas: Opportunities and risksQ39006342
Radiotherapy and radioembolization for liver metastasesQ39191482
Repetitive chemoembolization of hypovascular liver metastases from the most common primary sitesQ39455528
A phase II trial of nab-Paclitaxel as second-line therapy in patients with advanced pancreatic cancerQ40297178
Metastatic Pancreatic Adenocarcinoma Treatment Patterns, Health Care Resource Use, and Outcomes in France and the United Kingdom Between 2009 and 2012: A Retrospective StudyQ41021002
Italian cancer figures, report 2014: Prevalence and cure of cancer in ItalyQ41249095
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
P304page(s)27-43
P577publication date2016-02-10
P1433published inWorld journal of clinical oncologyQ27723540
P1476titleCurrent therapeutic strategies for advanced pancreatic cancer: A review for clinicians
P478volume7

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cites work (P2860)
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