The Emerging Roles of Gamma-Delta T Cells in Tissue Inflammation in Experimental Autoimmune Encephalomyelitis

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The Emerging Roles of Gamma-Delta T Cells in Tissue Inflammation in Experimental Autoimmune Encephalomyelitis is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.3389/FIMMU.2016.00014
P932PMC publication ID4731487
P698PubMed publication ID26858718

P2093author name stringAmit Awasthi
Muzamil Yaqub Want
Sakshi Malik
P2860cites workActivation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICAQ22010440
Role of gamma-delta (γδ) T cells in autoimmunityQ27008187
Role of two distinct γδ T cell subsets during West Nile virus infectionQ27489829
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cellsQ27860460
IL-17 and Th17 CellsQ27860566
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cellsQ27860620
Regulation of cutaneous malignancy by gammadelta T cellsQ28188439
Transforming growth factor-beta induces development of the T(H)17 lineageQ28237370
Skin gammadelta T-cell functions in homeostasis and wound healingQ28287572
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cellsQ28296956
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brainQ29614225
IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathwaysQ29614839
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generationQ29614840
Essential autocrine regulation by IL-21 in the generation of inflammatory T cellsQ29616147
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cellsQ29616148
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceQ29622850
IL-23 receptor regulates unconventional IL-17-producing T cells that control bacterial infectionsQ33693895
Gammadelta T cells in EAE: early trafficking events and cytokine requirementsQ33725068
Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanismQ33750530
The contribution of gammadelta T cells to the pathogenesis of EAE and MS.Q33753703
γδ T cell subsets play opposing roles in regulating experimental autoimmune encephalomyelitisQ33964713
Regulatory T cells and Foxp3Q34177949
CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsetsQ34205998
Protection of the intestinal mucosa by intraepithelial gamma delta T cellsQ34393641
γδ T cells enhance autoimmunity by restraining regulatory T cell responses via an interleukin-23-dependent mechanism.Q34434443
T cell response in experimental autoimmune encephalomyelitis (EAE): role of self and cross-reactive antigens in shaping, tuning, and regulating the autopathogenic T cell repertoireQ34542240
Gammadelta T cells: functional plasticity and heterogeneityQ34659133
RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation.Q34660473
The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.Q35049530
Virus-induced demyelination in nude mice is mediated by gamma delta T cells.Q35789290
Toll-like receptor 4 signaling in T cells promotes autoimmune inflammationQ36167500
Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.Q36189566
The recognition of the nonclassical major histocompatibility complex (MHC) class I molecule, T10, by the gammadelta T cell, G8.Q36377068
Granulocyte-macrophage colony-stimulating factor (GM-CSF) and T-cell responses: what we do and don't knowQ36394962
Gammadelta T cells - innate immune lymphocytes?Q36552480
Antigen recognition by gammadelta T cellsQ36732651
Caspase-1 regulates the inflammatory process leading to autoimmune demyelinationQ78145110
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
Role of gamma delta T cells in the inflammatory response of experimental colitis miceQ79274267
GM-CSF production by autoreactive T cells is required for the activation of microglial cells and the onset of experimental autoimmune encephalomyelitisQ79445107
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitisQ79755041
IL-17-mediated regulation of innate and acquired immune response against pulmonary Mycobacterium bovis bacille Calmette-Guerin infectionQ79880519
Resident Vdelta1+ gammadelta T cells control early infiltration of neutrophils after Escherichia coli infection via IL-17 productionQ79984931
Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammationQ80102514
Gamma delta T cell regulation of IFN-gamma production by central nervous system-infiltrating encephalitogenic T cells: correlation with recovery from experimental autoimmune encephalomyelitisQ80363030
Gamma delta T cells regulate the extent and duration of inflammation in the central nervous system by a Fas ligand-dependent mechanismQ81621858
gammadelta T-cell receptors: functional correlationsQ36732661
gammadelta T lymphocytes-selectable cells within the innate system?Q36749477
Most gamma delta T cells develop normally in beta 2-microglobulin-deficient miceQ36792726
IL-6 controls Th17 immunity in vivo by inhibiting the conversion of conventional T cells into Foxp3+ regulatory T cellsQ36985100
gammadelta T cells: an important source of IL-17.Q37012968
Gamma delta T-cell receptor repertoire in acute multiple sclerosis lesionsQ37018185
Th17 cell differentiation: the long and winding roadQ37133442
Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4(+) T cells and γδ T cellsQ37134804
Roles of heat shock proteins and gamma delta T cells in inflammationQ37195652
Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cellsQ37242180
Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells.Q37401753
Development and function of interleukin 17-producing γδ T cellsQ37975296
FOXP3 and scurfy: how it all beganQ38203784
Host T cells are the main producers of IL-17 within the central nervous system during initiation of experimental autoimmune encephalomyelitis induced by adoptive transfer of Th1 cell linesQ39975648
In vivo application of mAb directed against the gammadelta TCR does not deplete but generates "invisible" gammadelta T cellsQ40011743
Cutting edge: the pathogenicity of IFN-γ-producing Th17 cells is independent of T-betQ40021485
Involvement of IL-17 in Fas ligand-induced inflammationQ40538702
T cell antigen receptor engagement and specificity in the recognition of stress-inducible MHC class I-related chains by human epithelial gamma delta T cellsQ40716519
Gamma/delta cells.Q40898241
Decreased severity of myelin oligodendrocyte glycoprotein peptide 33 - 35-induced experimental autoimmune encephalomyelitis in mice with a disrupted TCR delta chain geneQ40911408
IL-15-secreting γδT cells induce memory T cells in experimental allergic encephalomyelitis (EAE) miceQ40939436
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitisQ42013994
A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis.Q42767100
Interleukin-1 and IL-23 induce innate IL-17 production from gammadelta T cells, amplifying Th17 responses and autoimmunity.Q43291517
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signalsQ43291519
Gammadelta T cells enhance the expression of experimental autoimmune encephalomyelitis by promoting antigen presentation and IL-12 productionQ47309507
The effect of gammadelta T cell depletion on cytokine gene expression in experimental allergic encephalomyelitis.Q47936770
Gamma delta T cell receptor repertoire in brain lesions of patients with multiple sclerosisQ48111929
Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences.Q48389926
Differential expression of β2 -integrins and cytokine production between γδ and αβ T cells in experimental autoimmune encephalomyelitisQ49922560
IL-17 production is dominated by gammadelta T cells rather than CD4 T cells during Mycobacterium tuberculosis infection.Q50715057
Identification of CD25+ gamma delta T cells as fetal thymus-derived naturally occurring IL-17 producers.Q51947657
Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).Q52519041
The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity.Q53820832
Caspase-1-processed cytokines IL-1beta and IL-18 promote IL-17 production by gammadelta and CD4 T cells that mediate autoimmunity.Q54379135
A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.Q55045567
Identification of a putative second T-cell receptor.Q55061010
Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivoQ59054431
IL23R: a susceptibility locus for celiac disease and multiple sclerosis?Q63197963
Most gamma delta T cells develop normally in the absence of MHC class II moleculesQ70504017
A pathogenic role for gamma delta T cells in relapsing-remitting experimental allergic encephalomyelitis in the SJL mouseQ71384783
T cell receptor usage in autoimmune diseaseQ71573103
Gamma delta T cell receptor variable region usage during the development of experimental allergic encephalomyelitisQ71586060
Aggravation of murine experimental allergic encephalomyelitis by administration of T-cell receptor gammadelta-specific antibodyQ73128587
A population of murine gammadelta T cells that recognize an inducible MHC class Ib moleculeQ73352533
IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cellsQ74279845
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
experimental autoimmune encephalomyelitisQ494066
P304page(s)14
P577publication date2016-01-01
P1433published inFrontiers in ImmunologyQ27723748
P1476titleThe Emerging Roles of Gamma-Delta T Cells in Tissue Inflammation in Experimental Autoimmune Encephalomyelitis
P478volume7

Reverse relations

cites work (P2860)
Q49834129GPR65 inhibits experimental autoimmune encephalomyelitis through CD4+ T cell independent mechanisms that include effects on iNKT cells
Q55190074Heat shock protein 70 protects mouse against post-infection irritable bowel syndrome via up-regulating intestinal γδ T cell's Th17 response.
Q39314770IL-17+ γδ T cells as kick-starters of inflammation.
Q40216414Immune-checkpoint protein VISTA critically regulates the IL-23/IL-17 inflammatory axis
Q99417890Inhibition of the activation of γδT17 cells through PPARγ-PTEN/Akt/GSK3β/NFAT pathway contributes to the anti-colitis effect of madecassic acid
Q63363253Innate, innate-like and adaptive lymphocytes in the pathogenesis of MS and EAE
Q88652087Integration of T-cell receptor, Notch and cytokine signals programs mouse γδ T-cell effector differentiation
Q90675719Interleukin 23 and autoimmune diseases: current and possible future therapies
Q39353100New Insights into the Role of IL-1β in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
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Q64063170The Pivotal Role of Regulatory T Cells in the Regulation of Innate Immune Cells
Q60301933Unexpected alliance between syndecan-1 and innate-like T cells to protect host from autoimmune effects of interleukin-17
Q90047092γδ T cells in rheumatic diseases: from fundamental mechanisms to autoimmunity
Q47215543γδ T cells provide the early source of IFN-γ to aggravate lesions in spinal cord injury

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