Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus

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Tenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus is …
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scholarly articleQ13442814

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P356DOI10.1016/J.ANTIVIRAL.2015.11.009
P698PubMed publication ID26640223
P5875ResearchGate publication ID284913859

P50authorAdrian S. RayQ40567817
P2093author name stringMichael J M Hitchcock
Marshall W Fordyce
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Tenofovir alafenamide is not a substrate for renal organic anion transporters (OATs) and does not exhibit OAT-dependent cytotoxicityQ39008333
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Implications of efficient hepatic delivery by tenofovir alafenamide (GS-7340) for hepatitis B virus therapyQ40676324
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Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate in the First Protease Inhibitor-Based Single-Tablet Regimen for Initial HIV-1 Therapy: A Randomized Phase 2 StudyQ41339429
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Selective intracellular activation of a novel prodrug of the human immunodeficiency virus reverse transcriptase inhibitor tenofovir leads to preferential distribution and accumulation in lymphatic tissueQ33769993
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Toxicity of antiviral nucleoside analogs and the human mitochondrial DNA polymerase.Q34088490
Metabolism of GS-7340, a novel phenyl monophosphoramidate intracellular prodrug of PMPA, in bloodQ34091731
Changes in the risk of death after HIV seroconversion compared with mortality in the general populationQ34791057
Pharmacokinetics of long-acting tenofovir alafenamide (GS-7340) subdermal implant for HIV prophylaxisQ35746114
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Characterization of HIV-1 Resistance to Tenofovir Alafenamide In VitroQ36076011
Markers of renal disease and function are associated with systemic inflammation in HIV infectionQ36206108
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Association of tenofovir exposure with kidney disease risk in HIV infectionQ37077982
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Mechanism of active renal tubular efflux of tenofovirQ38665179
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P407language of work or nameEnglishQ1860
P921main subjectvirologyQ7215
tenofovirQ155954
tenofovir alafenamide fumarateQ27162911
P304page(s)63-70
P577publication date2016-01-01
P1433published inAntiviral ResearchQ4775352
P1476titleTenofovir alafenamide: A novel prodrug of tenofovir for the treatment of Human Immunodeficiency Virus
P478volume125

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