Cadmium Protection Strategies--A Hidden Trade-Off?

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Cadmium Protection Strategies--A Hidden Trade-Off? is …
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review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/IJMS17010139
P8608Fatcat IDrelease_s4vcqhu5o5bijlhkhrq45nu2ba
P932PMC publication ID4730378
P698PubMed publication ID26805823
P5875ResearchGate publication ID291529974

P50authorMartina HöcknerQ59683298
P2093author name stringAdolf Michael Sandbichler
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Induction of the multixenobiotic defense mechanism (MXR), P-glycoprotein, in the mussel Mytilus californianus as a general cellular response to environmental stressesQ73800907
Oxidative mechanisms in the toxicity of chromium and cadmium ionsQ74307091
How water oxygenation level influences cadmium accumulation pattern in the Asiatic clam Corbicula fluminea: a laboratory and field studyQ74423046
The possible role of cytokeratin 8 in cadmium-induced adaptation and carcinogenesisQ79856293
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Roles of reactive oxygen species and mitochondria in cadmium-induced injury of liver cellsQ82837336
Functional comparison of metallothioneins MTT1 and MTT2 from Tetrahymena thermophilaQ83479158
Ascorbic acid protects against cadmium-induced endoplasmic reticulum stress and germ cell apoptosis in testesQ84089271
Coping with cadmium exposure in various ways: the two helicid snails Helix pomatia and Cantareus aspersus share the metal transcription factor-2, but differ in promoter organization and transcription of their Cd-metallothionein genesQ84428435
The hormesis database: the occurrence of hormetic dose responses in the toxicological literatureQ84432510
A rapid and transient ROS generation by cadmium triggers apoptosis via caspase-dependent pathway in HepG2 cells and this is inhibited through N-acetylcysteine-mediated catalase upregulationQ40372180
Transcriptional regulation of thioredoxin reductase 1 expression by cadmium in vascular endothelial cells: role of NF-E2-related factor-2.Q40496967
Metallothionein gene activation in the earthworm (Lumbricus rubellus).Q40527038
Domain Selection in Metallothionein 1A: Affinity-Controlled Mechanisms of Zinc Binding and Cadmium Exchange.Q40744717
Glutathione reductase, selenium-dependent glutathione peroxidase, glutathione levels, and lipid peroxidation in freshwater bivalves, Unio tumidus, as biomarkers of aquatic contamination in field studies.Q40870234
Short-term, low-dose cadmium exposure induces hyperpermeability in human renal glomerular endothelial cellsQ40901108
Implication of free radicals and glutathione in the mechanism of cadmium-induced expression of stress proteins in the A549 human lung cell-lineQ40906162
Concentration-dependent differential effects of N-acetyl-L-cysteine on the expression of HSP70 and metallothionein genes induced by cadmium in human amniotic cellsQ41050647
N-acetylcysteine effectively mitigates cadmium-induced oxidative damage and cell death in Leydig cells in vitro.Q41055755
Oxidative stress-induced cadmium resistance in Chinese hamster V79 cellsQ41151508
The sea urchin metallothionein system: Comparative evaluation of the SpMTA and SpMTB metal-binding preferences.Q41262991
Cadmium-induced DNA strand damage in cultured liver cells: reduction in cadmium genotoxicity following zinc pretreatmentQ41630960
Glutathione is the antioxidant responsible for resistance to oxidative stress in V79 Chinese hamster fibroblasts rendered resistant to cadmiumQ41637094
Differential transcytosis and toxicity of the hNGAL receptor ligands cadmium-metallothionein and cadmium-phytochelatin in colon-like Caco-2 cells: implications for in vivo cadmium toxicityQ42454005
Effects of acclimation temperature and cadmium exposure on cellular energy budgets in the marine mollusk Crassostrea virginica: linking cellular and mitochondrial responsesQ42492358
Alterations in cytoskeletal organization and homeostasis of cellular thiols in cadmium-resistant cellsQ42500962
Physiological relevance and contribution to metal balance of specific and non-specific Metallothionein isoforms in the garden snail, Cantareus aspersus.Q42602994
Acute effect of copper and cadmium exposure on the expression of heat shock protein 70 in the Cyprinidae fish Tanichthys albonubesQ42686987
Ameliorative Effects of Selenium on Cadmium-Induced Oxidative Stress and Endoplasmic Reticulum Stress in the Chicken KidneyQ42702192
FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activationQ42703679
Cadmium-induced injury and the ameliorative effects of selenium on chicken splenic lymphocytes: mechanisms of oxidative stress and apoptosisQ42704796
Protective effect of zinc supplementation against cadmium-induced oxidative stress and the RANK/RANKL/OPG system imbalance in the bone tissue of ratsQ42710904
Cadmium(Cd)-induced oxidative stress down-regulates the gene expression of DNA mismatch recognition proteins MutS homolog 2 (MSH2) and MSH6 in zebrafish (Danio rerio) embryosQ42714333
Role of megalin and the soluble form of its ligand RAP in Cd-metallothionein endocytosis and Cd-metallothionein-induced nephrotoxicity in vivo.Q42717952
Protective effect of quercetin on cadmium-induced oxidative toxicity on germ cells in male miceQ42749832
Quercetin attenuates cadmium-induced oxidative damage and apoptosis in granulosa cells from chicken ovarian folliclesQ42755330
Cadmium – glutathione solution structures provide new insights into heavy metal detoxificationQ42814041
Endoplasmic reticulum stress and alteration in calcium homeostasis are involved in cadmium-induced apoptosisQ42827151
Royal jelly (honey bee) is a potential antioxidant against cadmium-induced genotoxicity and oxidative stress in albino miceQ43204983
Melatonin administration ameliorates cadmium-induced oxidative stress and morphological changes in the liver of rat.Q43242460
Cadmium directly induced the opening of membrane permeability pore of mitochondria which possibly involved in cadmium-triggered apoptosisQ43720763
The use of the oxidative stress responses as biomarkers in Nile tilapia (Oreochromis niloticus) exposed to in vivo cadmium contaminationQ43947972
Influence of temperature, pH, oxygenation, water-type and substrate on biomarker responses in the freshwater clam Corbicula fluminea (Müller).Q44011929
Influence of antioxidants on metallothionein-mediated protection in cadmium-fed ratsQ44063605
Evolution of metallotionein isoforms complexes in hepatic cells of Mus musculus along cadmium exposureQ44158981
Action of green tea catechin on bone metabolic disorder in chronic cadmium-poisoned ratsQ44514361
Comparative analysis of antioxidants against cadmium induced reproductive toxicity in adult male ratsQ44554603
A proposed sequence of events for cadmium-induced mitochondrial impairment.Q44597850
Protective influence of vitamin E on antioxidant defense system in the blood of rats treated with cadmiumQ44611945
Use of Hsf1−/− mice reveals an essential role for HSF1 to protect lung against cadmium-induced injuryQ44614562
Antioxidant enzyme activities, metallothioneins and lipid peroxidation as biomarkers in Ruditapes decussatus?Q44676173
The protective effects of selenium on cadmium-induced oxidative stress and apoptosis via mitochondria pathway in mice kidneyQ44766739
Induction of a multixenobiotic resistance protein (MXR) in the Asiatic clam Corbicula fluminea after heavy metals exposureQ44844705
The effect of curcumin on cadmium-induced oxidative damage and trace elements level in the liver of rats and mice.Q44921248
Endoplasmic reticulum is a major target of cadmium toxicity in yeast.Q44961769
Differential HSP70 expression in Mytilus coruscus under various stressorsQ44978965
Physiological effects of dietary cadmium acclimation and waterborne cadmium challenge in rainbow trout: respiratory, ionoregulatory, and stress parametersQ45157731
Ascorbic acid, garlic extract and taurine alleviate cadmium-induced oxidative stress in freshwater catfish (Clarias batrachus).Q45954522
Cadmium-induced hepatotoxicity in rats and the protective effect of naringenin.Q46028316
The protection of selenium on ROS mediated-apoptosis by mitochondria dysfunction in cadmium-induced LLC-PK(1) cellsQ46168801
Genetic and Histopathological Responses to Cadmium Toxicity in Rabbit's Kidney and Liver: Protection by Ginger (Zingiber officinale).Q46445365
Protective role of selenium against renal toxicity induced by cadmium in ratsQ46446446
Effects of cadmium exposure on expression and activity of P-glycoprotein in eastern oysters, Crassostrea virginica GmelinQ46614518
Impact of cadmium contamination and oxygenation levels on biochemical responses in the Asiatic clam Corbicula fluminea.Q46615647
Effect of the flavonoid quercetin on cadmium-induced hepatotoxicityQ46629077
Taurine plays a beneficial role against cadmium-induced oxidative renal dysfunctionQ46642544
Chemoprotective effect of monoisoamyl 2, 3-dimercaptosuccinate (MiADMS) on cytokines expression in cadmium chloride treated human lung cellsQ33896056
Antioxidant role of metallothioneins: a comparative overviewQ33896346
Multixenobiotic resistance as a cellular defense mechanism in aquatic organismsQ33905646
A cell-based system that recapitulates the dynamic light-dependent regulation of the vertebrate clockQ33943035
Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells.Q34282828
Protective effect of manganese in cadmium-induced hepatic oxidative damage, changes in cadmium distribution and trace elements level in miceQ34320148
Natural antioxidants protect against cadmium-induced damage during pregnancy and lactation in rats' pupsQ34369580
The role of chelation in the treatment of other metal poisoningsQ34376795
Melatonin Improves mitochondrial function by promoting MT1/SIRT1/PGC-1 alpha-dependent mitochondrial biogenesis in cadmium-induced hepatotoxicity in vitroQ34483955
Differences in the epigenetic regulation of MT-3 gene expression between parental and Cd+2 or As+3 transformed human urothelial cellsQ34586021
Metallothioneins and cancerQ34610906
A method to evaluate the efficiency of transfection reagents in an adherent zebrafish cell lineQ34628877
Cadmium induces the expression of Grp78, an endoplasmic reticulum molecular chaperone, in LLC-PK1 renal epithelial cellsQ34687452
N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytesQ34725811
Hormesis results in trade-offs with immunityQ34803441
Role of oxidative stress in cadmium toxicity and carcinogenesisQ34872539
Impaired endocytosis in proximal tubule from subchronic exposure to cadmium involves angiotensin II type 1 and cubilin receptors.Q35007884
Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicalsQ35033016
Chelation of cadmiumQ35034512
Zinc supplementation protects against cadmium accumulation and cytotoxicity in Madin-Darby bovine kidney cells.Q35221781
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cellsQ35626776
Curcumin regulates airway epithelial cell cytokine responses to the pollutant cadmiumQ35675278
Biotic ligand model, a flexible tool for developing site-specific water quality guidelines for metalsQ35983294
SIRT3-SOD2-mROS-dependent autophagy in cadmium-induced hepatotoxicity and salvage by melatoninQ36111628
Physiologic implications of metal-ion transport by ZIP14 and ZIP8Q36138755
Cadmium toxicity induces ER stress and apoptosis via impairing energy homoeostasis in cardiomyocytesQ36185263
Role of MTL-1, MTL-2, and CDR-1 in mediating cadmium sensitivity in Caenorhabditis elegansQ36383664
Cadmium: cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review).Q36637220
Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicityQ36738111
Nrf2 protection against liver injury produced by various hepatotoxicantsQ36913996
Converging concepts: adaptive response, preconditioning, and the Yerkes-Dodson Law are manifestations of hormesisQ36927845
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesQ37285838
Amelioration of Cadmium-Produced Teratogenicity and Genotoxicity in Mice Given Arthrospira maxima (Spirulina) TreatmentQ37393170
The role of metallothionein in oncogenesis and cancer prognosisQ37434879
Actin cytoskeleton redox proteome oxidation by cadmiumQ37440476
The role of zinc transporters in cadmium and manganese transport in mammalian cellsQ37449689
Cadmium and mitochondriaQ37586581
Catch me if you can! Novel aspects of cadmium transport in mammalian cellsQ37702866
Cadmium stress: an oxidative challenge.Q37723349
Mitochondria, reactive oxygen species and cadmium toxicity in the kidneyQ37736790
Thermal, high pressure, and electric field processing effects on plant cell membrane integrity and relevance to fruit and vegetable qualityQ37871081
Nematode and snail metallothioneins.Q37913148
The taste of heavy metals: gene regulation by MTF-1.Q37979934
Stress management at the ER: regulators of ER stress-induced apoptosisQ37990288
Effects of cadmium on the actin cytoskeleton in renal mesangial cells.Q38078008
Hormetic mechanismsQ38123216
Cadmium and cellular signaling cascades: interactions between cell death and survival pathwaysQ38132083
Interplay of calcium and cadmium in mediating cadmium toxicity.Q38181855
cAMP increasing agents prevent the stimulation of heat-shock protein 70 (HSP70) gene expression by cadmium chloride in human myeloid cell linesQ38293074
Antioxidants as a Potential Preventive and Therapeutic Strategy for Cadmium.Q38461007
Iron transport in the kidney: implications for physiology and cadmium nephrotoxicityQ38612279
Cadmium Induced Apoptosis in MG63 Cells by Increasing ROS, Activation of p38 MAPK and Inhibition of ERK 1/2 PathwaysQ38872281
Effects of cadmium on cell proliferation, apoptosis, and proto-oncogene expression in zebrafish liver cells.Q38934047
Arsenic, cadmium, mercury and nickel stimulate cell growth via NADPH oxidase activation.Q38935533
Glutathione and mitochondria determine acute defense responses and adaptive processes in cadmium-induced oxidative stress and toxicity of the kidneyQ38941228
Dynamin 1-like-dependent mitochondrial fission initiates overactive mitophagy in the hepatotoxicity of cadmiumQ39079771
In vitro protection by pyruvate against cadmium-induced cytotoxicity in hippocampal HT-22 cellsQ39095806
Hypothermal and hyperthermal acclimation differentially modulate cadmium accumulation and toxicity in the zebrafish.Q39482494
Cross-resistance of cadmium-resistant cells to manganese is associated with reduced accumulation of both cadmium and manganese.Q39617868
Influence of essential elements on cadmium uptake and toxicity in a unicellular green alga: the protective effect of trace zinc and cobalt concentrationsQ39623441
Protective effects of N-acetylcysteine against cadmium-induced damage in cultured rat normal liver cellsQ39624873
Autophagy involvement in cadmium resistance through induction of multidrug resistance-associated protein and counterbalance of endoplasmic reticulum stress WI38 lung epithelial fibroblast cellsQ39684757
Inactivation by oxidation and recruitment into stress granules of hOGG1 but not APE1 in human cells exposed to sub-lethal concentrations of cadmiumQ39791896
Activation of Nrf2 by cadmium and its role in protection against cadmium-induced apoptosis in rat kidney cellsQ39812532
The hormetic effect of cadmium on the activity of antioxidant enzymes in the earthworm Eisenia fetidaQ39888271
CFTR mediates cadmium-induced apoptosis through modulation of ROS level in mouse proximal tubule cells.Q39897208
Molecular identification and expression of heat shock cognate 70 (hsc70) and heat shock protein 70 (hsp70) genes in the Pacific oyster Crassostrea gigasQ39957436
Oxidative stress and DNA damage induced by cadmium in the human keratinocyte HaCaT cell line: role of glutathione in the resistance to cadmiumQ40039020
Megalin-dependent internalization of cadmium-metallothionein and cytotoxicity in cultured renal proximal tubule cellsQ40281044
Acquired cadmium resistance in metallothionein-I/II(-/-) knockout cells: role of the T-type calcium channel Cacnalpha1G in cadmium uptakeQ40352283
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmetalloproteinQ423350
organic chemistryQ11351
catalysisQ82264
peptideQ172847
inorganic compoundQ190065
mechanism of actionQ3271540
P304page(s)139
P577publication date2016-01-01
2016-01-21
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleCadmium Protection Strategies--A Hidden Trade-Off?
P478volume17

Reverse relations

cites work (P2860)
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Q91874559Zinc as a countermeasure for cadmium toxicity

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