The role of Reg IV in colorectal cancer, as a potential therapeutic target

scientific article

The role of Reg IV in colorectal cancer, as a potential therapeutic target is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.5114/WO.2015.54385
P932PMC publication ID4631303
P698PubMed publication ID26557771
P5875ResearchGate publication ID282776995

P2093author name stringChi Pan
Suzhan Zhang
Jiyi Hu
Yiwang Hu
P2860cites workGlobal cancer statisticsQ22241238
The PI3K-PDK1 connection: more than just a road to PKBQ24531972
Loss of CDX2 expression and microsatellite instability are prominent features of large cell minimally differentiated carcinomas of the colonQ24685680
5-Fluorouracil: mechanisms of action and clinical strategiesQ28201937
Systematic search for gastric cancer-specific genes based on SAGE data: melanoma inhibitory activity and matrix metalloproteinase-10 are novel prognostic factors in patients with gastric cancerQ28285287
Molecular cloning, sequencing and expression of the mRNA encoding human Cdx1 and Cdx2 homeobox. Down-regulation of Cdx1 and Cdx2 mRNA expression during colorectal carcinogenesisQ28303785
Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancerQ29616236
Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV.Q30664438
Molecular diagnosis of colorectal tumors by expression profiles of 50 genes expressed differentially in adenomas and carcinomasQ31064531
Reg IV, a differentially expressed gene in colorectal adenoma.Q31150381
Expression of the REG IV gene in ulcerative colitisQ33270662
Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosisQ33643086
Bcl-2 proteins: regulators of apoptosis or of mitochondrial homeostasis?Q33787932
Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomasQ34161211
The Cdx2 homeobox gene has a tumour suppressor function in the distal colon in addition to a homeotic role during gut development.Q34229849
Overexpression of Reg IV in colorectal adenomaQ34269057
Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancerQ34469547
Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomasQ34482693
Expression profile of the REG gene family in colorectal carcinomaQ35440602
Reg gene family and human diseasesQ35605611
Regenerating islet-derived family member, 4 modulates multiple receptor tyrosine kinases and mediators of drug resistance in cancerQ39568944
Anti-tumor effects of proteoglycan from Phellinus linteus by immunomodulating and inhibiting Reg IV/EGFR/Akt signaling pathway in colorectal carcinomaQ39603741
Reg IV is a serum biomarker for gastric cancer patients and predicts response to 5-fluorouracil-based chemotherapyQ40180989
Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinomaQ40387409
REG Ialpha protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer.Q40447195
Activator protein accelerates dihydropyrimidine dehydrogenase gene transcription in cancer cells.Q40459599
Protein-bound polysaccharide from Phellinus linteus induces G2/M phase arrest and apoptosis in SW480 human colon cancer cells.Q40494425
Matrilysin (MMP-7) induces homotypic adhesion of human colon cancer cells and enhances their metastatic potential in nude mouse modelQ40612590
Current status of colorectal cancer: CPT-11 (irinotecan), a therapeutic innovationQ40955954
Retroviral transduction of human dihydropyrimidine dehydrogenase cDNA confers resistance to 5-fluorouracil in murine hematopoietic progenitor cells and human CD34+-enriched peripheral blood progenitor cellsQ42820147
Expression profile of REG family proteins REG Ialpha and REG IV in advanced gastric cancer: comparison with mucin phenotype and prognostic markers.Q51746168
Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer.Q54298121
CDX2, a highly sensitive and specific marker of adenocarcinomas of intestinal origin: an immunohistochemical survey of 476 primary and metastatic carcinomasQ73045412
Homeodomain protein CDX2 regulates goblet-specific MUC2 gene expressionQ78862429
Serum concentration of Reg IV in patients with colorectal cancer: overexpression and high serum levels of Reg IV are associated with liver metastasisQ80477317
Relationship between RegIV gene expression to outcomes in colorectal cancerQ83549934
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectcolorectal cancerQ188874
P304page(s)261-4
P577publication date2015-01-01
P1433published inContemporary oncologyQ26841968
P1476titleThe role of Reg IV in colorectal cancer, as a potential therapeutic target
P478volume19

Reverse relations

cites work (P2860)
Q38746037Overexpression of Long Non-Coding RNA TUG1 Promotes Colon Cancer Progression
Q40101289Regenerating Family Member 4 (Reg4) Enhances 5-Fluorouracil Resistance of Gastric Cancer Through Activating MAPK/Erk/Bim Signaling Pathway

Search more.