Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts

scientific article

Protein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/IJMS161125971
P932PMC publication ID4661830
P698PubMed publication ID26556350
P5875ResearchGate publication ID283717109

P2093author name stringMarie-Hélène David-Cordonnier
Sabine Depauw
Gaëlle Savreux-Lenglet
P2860cites workProtein recognition of the S23906-1-DNA adduct by nuclear proteins: direct involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH)Q86118864
Binding and modulation of p53 by p300/CBP coactivatorsQ24312018
Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosisQ24652801
Binding of the human nucleotide excision repair proteins XPA and XPC/HR23B to the 5R-thymine glycol lesion and structure of the cis-(5R,6S) thymine glycol epimer in the 5'-GTgG-3' sequence: destabilization of two base pairs at the lesion siteQ27658074
Genome maintenance mechanisms for preventing cancerQ28131737
S phase activation of the histone H2B promoter by OCA-S, a coactivator complex that contains GAPDH as a key componentQ28190509
GAPDH as a housekeeping gene: analysis of GAPDH mRNA expression in a panel of 72 human tissuesQ28239983
The birth of chemotherapy at Yale. Bicentennial lecture series: Surgery Grand RoundQ28241501
GAPDH: a common enzyme with uncommon functionsQ28247287
Structural analysis of glyceraldehyde-3-phosphate dehydrogenase functional diversityQ28249264
A dimer interface mutation in glyceraldehyde-3-phosphate dehydrogenase regulates its binding to AU-rich RNAQ28252728
S-nitrosylated GAPDH initiates apoptotic cell death by nuclear translocation following Siah1 bindingQ28256078
The macrophage cell surface glyceraldehyde-3-phosphate dehydrogenase is a novel transferrin receptorQ28275180
The expression of glyceraldehyde-3-phosphate dehydrogenase associated cell cycle (GACC) genes correlates with cancer stage and poor survival in patients with solid tumorsQ28289698
The diverse functions of GAPDH: views from different subcellular compartmentsQ28291106
GOSPEL: a neuroprotective protein that binds to GAPDH upon S-nitrosylationQ28570143
DNA repair pathways as targets for cancer therapyQ29615572
LEF-1 recognition of platinated GG sequences within double-stranded DNA. Influence of flanking bases.Q38297031
High mobility group 1 and 2 proteins bind preferentially to DNA that contains bulky adducts induced by benzo[a]pyrene diol epoxide and N-acetoxy-acetylaminofluorene.Q38309426
DNA sequence context modulates the impact of a cisplatin 1,2-d(GpG) intrastrand cross-link on the conformational and thermodynamic properties of duplex DNA.Q38314491
A pyrazolato-bridged dinuclear platinum(II) complex induces only minor distortions upon DNA-bindingQ38315298
Sequence-dependent distortions induced in DNA by monofunctional platinum(II) bindingQ38323567
Covalent binding of antitumor benzoacronycines to double-stranded DNA induces helix opening and the formation of single-stranded DNA: unique consequences of a novel DNA-bonding mechanism.Q38331782
DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).Q38333904
DNA sequence- and structure-selective alkylation of guanine N2 in the DNA minor groove by ecteinascidin 743, a potent antitumor compound from the Caribbean tunicate Ecteinascidia turbinataQ38352293
Binding discrimination of MutS to a set of lesions and compound lesions (base damage and mismatch) reveals its potential role as a cisplatin-damaged DNA sensing proteinQ38356417
Role of base flipping in specific recognition of damaged DNA by repair enzymes.Q38361321
Critical protein GAPDH and its regulatory mechanisms in cancer cellsQ38413973
Disruption of the nuclear p53-GAPDH complex protects against ischemia-induced neuronal damageQ38755737
GAPDH binds to active Akt, leading to Bcl-xL increase and escape from caspase-independent cell death.Q39156134
UCP2 inhibition triggers ROS-dependent nuclear translocation of GAPDH and autophagic cell death in pancreatic adenocarcinoma cells.Q39249828
Glyceraldehyde-3-phosphate dehydrogenase regulates cyclooxygenase-2 expression by targeting mRNA stabilityQ39274062
CIB1 prevents nuclear GAPDH accumulation and non-apoptotic tumor cell death via AKT and ERK signalingQ39281845
Overexpression of glutaredoxin protects cardiomyocytes against nitric oxide-induced apoptosis with suppressing the S-nitrosylation of proteins and nuclear translocation of GAPDH.Q39305711
Binding of glyceraldehyde-3-phosphate dehydrogenase to the cis-acting element of structure-anchored repression in ccn2 mRNA.Q39607818
Influence of the stereoisomeric position of the reactive acetate groups of the benzo[b]acronycine derivative S23906-1 on its DNA alkylation, helix-opening, cytotoxic, and antitumor activitiesQ39799890
Posttranscriptional regulation of angiotensin II type 1 receptor expression by glyceraldehyde 3-phosphate dehydrogenaseQ39879276
Human glyceraldehyde-3-phosphate dehydrogenase plays a direct role in reactivating oxidized forms of the DNA repair enzyme APE1.Q39942445
Glyceraldehyde-3-phosphate dehydrogenase enhances transcriptional activity of androgen receptor in prostate cancer cellsQ40123008
Effect of N-2-acetylaminofluorene and 2-aminofluorene adducts on DNA binding and synthesis by yeast DNA polymerase eta.Q40246661
Conformation of DNA GG intrastrand cross-link of antitumor oxaliplatin and its enantiomeric analog.Q40320273
SJG-136 (NSC 694501), a novel rationally designed DNA minor groove interstrand cross-linking agent with potent and broad spectrum antitumor activity: part 1: cellular pharmacology, in vitro and initial in vivo antitumor activityQ40514663
Rapid shortening of telomere length in response to ceramide involves the inhibition of telomere binding activity of nuclear glyceraldehyde-3-phosphate dehydrogenaseQ40614792
A Novel CRM1-mediated Nuclear Export Signal Governs Nuclear Accumulation of Glyceraldehyde-3-phosphate Dehydrogenase following Genotoxic StressQ40616428
A nuclear protein complex containing high mobility group proteins B1 and B2, heat shock cognate protein 70, ERp60, and glyceraldehyde-3-phosphate dehydrogenase is involved in the cytotoxic response to DNA modified by incorporation of anticancer nuclQ40679002
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interacts with apurinic/apyrimidinic sites in DNA.Q40704579
Brostallicin, a novel anticancer agent whose activity is enhanced upon binding to glutathione.Q40737953
Glyceraldehyde-3-phosphate dehydrogenase associates with actin filaments in serum deprived NIH 3T3 cells onlyQ40750901
Induction of cyclin E and inhibition of DNA synthesis by the novel acronycine derivative S23906-1 precede the irreversible arrest of tumor cells in S phase leading to apoptosis.Q40766489
Okadaic acid induces transcription of junB through a CCAAT box and NF-Y.Q40811678
Design, synthesis, and evaluation of a novel pyrrolobenzodiazepine DNA-interactive agent with highly efficient cross-linking ability and potent cytotoxicityQ40819330
Opposite effects of cell differentiation and apoptosis on Ap3A/Ap4A ratio in human cell culturesQ41082711
Loss of DNA mismatch repair in acquired resistance to cisplatinQ41189901
Glyceraldehyde-3-phosphate dehydrogenase regulates endothelin-1 expression by a novel, redox-sensitive mechanism involving mRNA stability.Q41356595
Evaluation of the cytotoxic mechanisms mediated by the broad-spectrum antitumor alkaloid acronycine and selected semisynthetic derivativesQ41644833
Rab2 utilizes glyceraldehyde-3-phosphate dehydrogenase and protein kinase C{iota} to associate with microtubules and to recruit dyneinQ42121385
Involvement of high mobility group B proteins in cisplatin-induced cytotoxicity in squamous cell carcinoma of skin.Q42163245
Is GAPDH a relevant housekeeping gene for normalisation in colorectal cancer experiments?Q42346264
S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1-GAPDH death cascadeQ42545938
Strand opening by the UvrA(2)B complex allows dynamic recognition of DNA damageQ42680761
Paraquat exposure induces nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and the activation of the nitric oxide-GAPDH-Siah cell death cascade.Q43061139
Energetics, conformation, and recognition of DNA duplexes modified by monodentate Ru(II) complexes containing terphenyl arenesQ43106305
Biophysical studies on the stability of DNA intrastrand cross-links of transplatin.Q43222524
Brostallicin (PNU-166196), a new minor groove DNA binder: preclinical and clinical activityQ43235606
An unusual DNA binding compound, S23906, induces mitotic catastrophe in cultured human cellsQ43275764
New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.Q30322264
Evidence for thiol/disulfide exchange reactions between tubulin and glyceraldehyde-3-phosphate dehydrogenase.Q30370225
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseasesQ30372906
Exploring damage recognition models in prokaryotic nucleotide excision repair with a benzo[a]pyrene-derived lesion in UvrBQ30497240
Replication protein A (RPA) binding to duplex cisplatin-damaged DNA is mediated through the generation of single-stranded DNA.Q30631650
Recognition of nonhybridizing base pairs during nucleotide excision repair of DNAQ30639682
The NER proteins XPC and CSB, but not ERCC1, regulate the sensitivity to the novel DNA binder S23906: implications for recognition and repair of antitumor alkylators.Q30981252
Antiproliferative activity of ecteinascidin 743 is dependent upon transcription-coupled nucleotide-excision repair.Q30998417
Interactions of human replication protein A with single-stranded DNA adductsQ31111443
Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding proteinQ31151074
A novel protein complex distinct from mismatch repair binds thioguanylated DNA.Q31843972
Base selectivity and effects of sequence and DNA secondary structure on the formation of covalent adducts derived from the equine estrogen metabolite 4-hydroxyequilenin.Q33227572
Specific and efficient binding of xeroderma pigmentosum complementation group A to double-strand/single-strand DNA junctions with 3'- and/or 5'-ssDNA branchesQ33266920
Regulation of oncogenic transcription factor hTAF(II)68-TEC activity by human glyceraldehyde-3-phosphate dehydrogenase (GAPDH).Q33273931
Recognition of cisplatin-DNA interstrand cross-links by replication protein A.Q33363632
Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedinQ33377399
Activation of AMP-activated protein kinase stimulates the nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in human diploid fibroblastsQ33533561
Moonlighting proteins.Q33543960
Reactions of glyceraldehyde 3-phosphate dehydrogenase sulfhydryl groups with bis-electrophiles produce DNA-protein cross-links but not mutationsQ33726109
Ataxia telangiectasia mutated- and Rad3-related kinase drives both the early and the late DNA-damage response to the monofunctional antitumour alkylator S23906.Q33864110
Novel irreversible small molecule inhibitors of replication protein A display single-agent activity and synergize with cisplatinQ33994331
DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular ConsequencesQ34042848
Oxidatively modified glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's disease: many pathways to neurodegenerationQ34071097
Teratogen-Induced Oxidative Stress Targets Glyceraldehyde-3-Phosphate Dehydrogenase in the Organogenesis Stage Mouse EmbryoQ34322036
The antitumor agent ecteinascidin 743: characterization of its covalent DNA adducts and chemical stability.Q34476352
Effect of ecteinascidin-743 on the interaction between DNA binding proteins and DNA.Q34505128
Ecteinascidin-743 inhibits activated but not constitutive transcription.Q34524124
Ecteinascidin 743: a novel anticancer drug with a unique mechanism of actionQ34526125
Cross-talk between nucleotide excision and homologous recombination DNA repair pathways in the mechanism of action of antitumor trabectedinQ34570044
Interaction of TPPP/p25 protein with glyceraldehyde-3-phosphate dehydrogenase and their co-localization in Lewy bodiesQ34572066
Glyceraldehyde-3-phosphate dehydrogenase interacts with proapoptotic kinase mst1 to promote cardiomyocyte apoptosisQ34634209
Sulfur mustard induced nuclear translocation of glyceraldehyde-3-phosphate-dehydrogenase (GAPDH).Q34799040
Role of apoptosis signal-regulating kinase 1 (ASK1) as an activator of the GAPDH-Siah1 stress-signaling cascadeQ34801671
Chemical inhibitor targeting the replication protein A-DNA interaction increases the efficacy of Pt-based chemotherapy in lung and ovarian cancerQ34849073
Identification of GAPDH as a protein target of the saframycin antiproliferative agentsQ37645294
Human AP endonuclease 1 (APE1): from mechanistic insights to druggable target in cancer.Q37670414
On the functional diversity of glyceraldehyde-3-phosphate dehydrogenase: biochemical mechanisms and regulatory controlQ37884659
Basic biology of GAPDH.Q38031191
Compartmentation of GAPDH.Q38031193
Novel insight into the role of GAPDH playing in tumorQ38036608
Glyceraldehyde-3-phosphate dehydrogenase: a promising target for molecular therapy in hepatocellular carcinomaQ38042261
Deregulation of glycolysis in cancer: glyceraldehyde-3-phosphate dehydrogenase as a therapeutic targetQ38085071
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and Alzheimer's diseaseQ38253288
Protein moonlighting: a new factor in biology and medicineQ38268466
Oxidative modifications of glyceraldehyde-3-phosphate dehydrogenase play a key role in its multiple cellular functionsQ43299556
Synthesis and cytotoxic and antitumor activity of benzo[b]pyrano[3, 2-h]acridin-7-one analogues of acronycineQ43504763
Hierarchy of DNA damage recognition in Escherichia coli nucleotide excision repairQ43547641
The cost of DNA bendingQ43566240
Marked antitumor activity of a new potent acronycine derivative in orthotopic models of human solid tumors.Q43698960
Induction of apoptosis in HL-60 leukemia and B16 melanoma cells by the acronycine derivative S23906-1.Q43984001
Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activityQ44006810
Alkylation of guanine in DNA by S23906-1, a novel potent antitumor compound derived from the plant alkaloid acronycineQ44082093
New antitumor agents in the acronycine seriesQ44178245
Lactate dehydrogenase and glyceraldehyde-phosphate dehydrogenase are single-stranded DNA-binding proteins that affect the DNA-polymerase-alpha-primase complexQ44465149
Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1.Q44489242
Oxidation of glyceraldehyde-3-phosphate dehydrogenase enhances its binding to nucleic acidsQ44533951
DNA Interactions of Monofunctional Organometallic Ruthenium(II) Antitumor Complexes in Cell-free MediaQ44600759
Effect of BRCA1 and XPG mutations on treatment response to trabectedin and pegylated liposomal doxorubicin in patients with advanced ovarian cancer: exploratory analysis of the phase 3 OVA-301 studyQ44655765
A transesterification reaction is implicated in the covalent binding of benzo[b]acronycine anticancer agents with DNA and glutathionQ44707659
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classesQ45144293
Conformation of DNA modified by monofunctional Ru(II) arene complexes: recognition by DNA binding proteins and repair. Relationship to cytotoxicity.Q45233943
Histone 2B (H2B) expression is confined to a proper NAD+/NADH redox statusQ46444370
Regulation of plant cytosolic glyceraldehyde 3-phosphate dehydrogenase isoforms by thiol modificationsQ46735017
Equilenin-derived DNA adducts to cytosine in DNA duplexes: structures and thermodynamicsQ46785126
Unique properties of DNA interstrand cross-links of antitumor oxaliplatin and the effect of chirality of the carrier ligand.Q46893533
The evaluation of nitric oxide scavenging activity of certain herbal formulations in vitro: a preliminary studyQ47325343
Microtubule-associated protein 1B binds glyceraldehyde-3-phosphate dehydrogenaseQ48158887
Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase isoforms during neuronal apoptosisQ48275909
Glyceraldehyde-3-phosphate dehydrogenase is a nonhistone protein and a possible activator of transcription in neuronsQ48331174
Cerebral ischemia-reperfusion induces GAPDH S-nitrosylation and nuclear translocationQ48433772
Subcellular distribution of glyceraldehyde-3-phosphate dehydrogenase in cerebellar granule cells undergoing cytosine arabinoside-induced apoptosisQ48544021
Analysis of the binding of glyceraldehyde-3-phosphate dehydrogenase to microtubules, the mechanism of bundle formation and the linkage effectQ48876781
A history of cancer chemotherapyQ34869530
Yeast Tdh3 (glyceraldehyde 3-phosphate dehydrogenase) is a Sir2-interacting factor that regulates transcriptional silencing and rDNA recombinationQ35022326
Overexpression of FOXO3, MYD88, and GAPDH Identified by Suppression Subtractive Hybridization in Esophageal Cancer Is Associated with AutophagyQ35094166
Glyceraldehyde 3-phosphate dehydrogenase-telomere association correlates with redox status in Trypanosoma cruziQ35578401
Akt2 kinase suppresses glyceraldehyde-3-phosphate dehydrogenase (GAPDH)-mediated apoptosis in ovarian cancer cells via phosphorylating GAPDH at threonine 237 and decreasing its nuclear translocationQ35604944
Structural insights into the recognition of cisplatin and AAF-dG lesion by Rad14 (XPA)Q35671448
Design of novel antitumor DNA alkylating agents: the benzacronycine seriesQ35699547
Sequence preferences of DNA interstrand crosslinking agents: quantitation of interstrand crosslink locations in DNA duplex fragments containing multiple crosslinkable sitesQ35761618
Exocyclic amino groups of flanking guanines govern sequence-dependent adduct conformations and local structural distortions for minor groove-aligned benzo[a]pyrenyl-guanine lesions in a GG mutation hotspot contextQ35781834
Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activationQ35802323
Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743.Q35802653
HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nucleaseQ35852579
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) induces cancer cell senescence by interacting with telomerase RNA componentQ36170627
BRCA2 is needed for both repair and cell cycle arrest in mammalian cells exposed to S23906, an anticancer monofunctional DNA binder.Q36188973
A mutation in glyceraldehyde 3-phosphate dehydrogenase alters endocytosis in CHO cellsQ36235903
The efficiencies of damage recognition and excision correlate with duplex destabilization induced by acetylaminofluorene adducts in human nucleotide excision repairQ36413249
Nitric oxide-GAPDH-Siah: a novel cell death cascadeQ36457904
Identification of a myocyte nuclear factor that binds to the muscle-specific enhancer of the mouse muscle creatine kinase geneQ36757653
The multifunctional protein glyceraldehyde-3-phosphate dehydrogenase is both regulated and controls colony-stimulating factor-1 messenger RNA stability in ovarian cancerQ36982940
Deprenyl enhances the teratogenicity of hydroxyurea in organogenesis stage mouse embryosQ37000036
Structure and mechanism for DNA lesion recognitionQ37044560
Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoterQ37073959
Poly-ADP-ribose-polymerase inhibition ameliorates hind limb ischemia reperfusion injury in a murine model of type 2 diabetesQ37172217
Chromatin-associated proteins HMGB1/2 and PDIA3 trigger cellular response to chemotherapy-induced DNA damageQ37199282
Glyceraldehyde-3-phosphate dehydrogenase antisense oligodeoxynucleotides protect against cytosine arabinonucleoside-induced apoptosis in cultured cerebellar neuronsQ37368739
Damage detection and base flipping in direct DNA alkylation repairQ37369004
Glyceraldehyde 3-phosphate dehydrogenase depletion induces cell cycle arrest and resistance to antimetabolites in human carcinoma cell linesQ37397248
Direct binding of glyceraldehyde 3-phosphate dehydrogenase to telomeric DNA protects telomeres against chemotherapy-induced rapid degradationQ37462845
Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adductQ37522716
Dynamic two-stage mechanism of versatile DNA damage recognition by xeroderma pigmentosum group C proteinQ37581154
A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenaseQ37597621
Novel roles for GAPDH in cell death and carcinogenesis.Q37603056
Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities.Q50914964
The multifunctional glycolytic protein glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a novel macrophage lactoferrin receptor.Q51761328
Mechanism of interaction of CC-1065 (NSC 298223) with DNA.Q52504772
SIRT1 interacts with and protects glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from nuclear translocation: implications for cell survival after irradiation.Q53157483
Generation of replication-dependent double-strand breaks by the novel N2-G-alkylator S23906-1.Q53610678
Up-regulated autophagy by endogenous high mobility group box-1 promotes chemoresistance in leukemia cells.Q54352470
Increased DNA Binding Specificity for Antitumor Ecteinascidin 743 through Protein−DNA Interactions?Q57966463
DNA interactions of dinuclear RuII arene antitumor complexes in cell-free mediaQ60240455
The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedinQ60322887
Thermostability of double-stranded deoxyribonucleic acids: effects of covalent additions of a psoralenQ69685051
Biosynthesis of the human base excision repair enzyme uracil-DNA glycosylaseQ69686961
Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenaseQ70529043
Phase I-II evaluation of acronine in patients with multiple myelomaQ71030334
The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatinQ71533749
Uracil DNA-glycosylase/glyceraldehyde-3-phosphate dehydrogenase is an Ap4A binding proteinQ71936198
A mechlorethamine-induced DNA interstrand cross-link bends duplex DNAQ72422677
Alkaloids of Acronychia Baueri Schott I. Isolation of the alkaloids and a study of the antitumor and other biological properties of acronycineQ72933228
Involvement of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and p53 in neuronal apoptosis: evidence that GAPDH is upregulated by p53Q73107353
Alkaloids of the Australian RutaceæQ74207386
DNA bending by the human damage recognition complex XPC-HR23BQ78840506
Acronycine epoxide: a new acridone alkaloid from several Sarcomelicope speciesQ79694534
Trabectedin in patients with advanced non-small-cell lung cancer (NSCLC) with XPG and/or ERCC1 overexpression and BRCA1 underexpression and pretreated with platinumQ83131463
In the absence of cellular poly (A) binding protein, the glycolytic enzyme GAPDH translocated to the cell nucleus and activated the GAPDH mediated apoptotic pathway by enhancing acetylation and serine 46 phosphorylation of p53Q84026202
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectcatalysisQ82264
DNA-binding proteinQ2252764
mechanism of actionQ3271540
DNA adductsQ4153410
DNAQ7430
organic chemistryQ11351
P304page(s)26555-81
P577publication date2015-01-01
2015-11-05
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleProtein Recognition in Drug-Induced DNA Alkylation: When the Moonlight Protein GAPDH Meets S23906-1/DNA Minor Groove Adducts
P478volume16

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cites work (P2860)
Q55065423A cryoprotectant induces conformational change in glyceraldehyde-3-phosphate dehydrogenase.
Q48113343A modular design for minor groove binding and recognition of mixed base pair sequences of DNA.
Q47661718Data-Independent Mass Spectrometry Approach for Screening and Identification of DNA Adducts.
Q47214170High-affinity low-capacity and low-affinity high-capacity N-acetyl-2-aminofluorene (AAF) macromolecular binding sites are revealed during the growth cycle of adult rat hepatocytes in primary culture