scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1043042992 |
P356 | DOI | 10.1038/NM.3935 |
P3181 | OpenCitations bibliographic resource ID | 1657054 |
P932 | PMC publication ID | 4886231 |
P698 | PubMed publication ID | 26340119 |
P2093 | author name string | Guoping Feng | |
Tobias Kaiser | |||
P2860 | cites work | A mouse model that recapitulates cardinal features of the 15q13.3 microdeletion syndrome including schizophrenia- and epilepsy-related alterations | Q48959451 |
Altered default mode and fronto-parietal network subsystems in patients with schizophrenia and their unaffected siblings. | Q50652153 | ||
Evidence for impaired long-term potentiation in schizophrenia and its relationship to motor skill learning. | Q51899338 | ||
Structural and functional evolution of the basal ganglia in vertebrates | Q57540064 | ||
Translating cancer research into targeted therapeutics | Q59060386 | ||
Genetics of autism spectrum disorders | Q84797519 | ||
Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication | Q21198697 | ||
CNTNAP2 and NRXN1 are mutated in autosomal-recessive Pitt-Hopkins-like mental retardation and determine the level of a common synaptic protein in Drosophila | Q24315560 | ||
Mouse neurexin-1alpha deletion causes correlated electrophysiological and behavioral changes consistent with cognitive impairments | Q24328996 | ||
Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function | Q24338263 | ||
Biological insights from 108 schizophrenia-associated genetic loci | Q24561833 | ||
Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3 | Q24596677 | ||
Shank3 mutant mice display autistic-like behaviours and striatal dysfunction | Q24597501 | ||
Common genetic variants on 5p14.1 associate with autism spectrum disorders | Q24603204 | ||
Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses | Q24610600 | ||
A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice | Q24629938 | ||
Modelling schizophrenia using human induced pluripotent stem cells | Q24633007 | ||
Disruption of the neurexin 1 gene is associated with schizophrenia | Q24647095 | ||
Genetic variant BDNF (Val66Met) polymorphism alters anxiety-related behavior | Q24679793 | ||
Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors | Q26269833 | ||
The study of psychiatric disease genes and drugs in zebrafish | Q26824671 | ||
Genome-scale neurogenetics: methodology and meaning | Q26859474 | ||
High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder | Q27336312 | ||
Epigenetics of Stress-Related Psychiatric Disorders and Gene × Environment Interactions | Q28083023 | ||
Heritability estimates for psychotic disorders: the Maudsley twin psychosis series | Q28137629 | ||
The endophenotype concept in psychiatry: etymology and strategic intentions | Q28187744 | ||
Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin | Q28213213 | ||
Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche | Q28239639 | ||
Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2 | Q28268807 | ||
SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients | Q28300343 | ||
AMPAKINE enhancement of social interaction in the BTBR mouse model of autism | Q28388762 | ||
FOXG1-Dependent Dysregulation of GABA/Glutamate Neuron Differentiation in Autism Spectrum Disorders | Q28973611 | ||
Cerebral organoids model human brain development and microcephaly | Q28973619 | ||
Research domain criteria (RDoC): toward a new classification framework for research on mental disorders | Q29547877 | ||
Autism-like behavioral phenotypes in BTBR T+tf/J mice | Q29615512 | ||
A new initiative on precision medicine | Q29615654 | ||
Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease | Q29615682 | ||
Self-organizing optic-cup morphogenesis in three-dimensional culture | Q29616181 | ||
Structural and molecular interrogation of intact biological systems | Q29616195 | ||
Deficiency of methyl-CpG binding protein-2 in CNS neurons results in a Rett-like phenotype in mice | Q29616328 | ||
Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits | Q29618411 | ||
Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia | Q29618963 | ||
Animal models of neuropsychiatric disorders | Q29619899 | ||
A Model for Neural Development and Treatment of Rett Syndrome Using Human Induced Pluripotent Stem Cells | Q29619964 | ||
Stepwise evolution of stable sociality in primates | Q30085655 | ||
Wild-type microglia arrest pathology in a mouse model of Rett syndrome | Q30424614 | ||
Mouse models of gene-environment interactions in schizophrenia | Q30432026 | ||
Loss of predominant Shank3 isoforms results in hippocampus-dependent impairments in behavior and synaptic transmission | Q30438299 | ||
SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties | Q30438816 | ||
Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice | Q30461096 | ||
Gamma frequency-range abnormalities to auditory stimulation in schizophrenia | Q30481594 | ||
Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome | Q30529349 | ||
Optogenetic stimulation of lateral orbitofronto-striatal pathway suppresses compulsive behaviors | Q30561087 | ||
Repeated cortico-striatal stimulation generates persistent OCD-like behavior | Q30574071 | ||
FAAH genetic variation enhances fronto-amygdala function in mouse and human | Q30625337 | ||
A review of diffusion tensor imaging studies in schizophrenia | Q30994764 | ||
Neuroimaging and frontal-subcortical circuitry in obsessive-compulsive disorder. | Q31966529 | ||
Functional neuroimaging and the neuroanatomy of obsessive-compulsive disorder | Q33181070 | ||
Repetitive self-grooming behavior in the BTBR mouse model of autism is blocked by the mGluR5 antagonist MPEP. | Q33685348 | ||
Impaired hippocampal-prefrontal synchrony in a genetic mouse model of schizophrenia | Q33829829 | ||
Prioritization of neurodevelopmental disease genes by discovery of new mutations | Q33830995 | ||
The basal ganglia | Q33970931 | ||
A polygenic burden of rare disruptive mutations in schizophrenia | Q34060200 | ||
Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia. | Q34214883 | ||
Regionally localized thinning of the cerebral cortex in schizophrenia | Q34229033 | ||
Thalamic dysfunction in schizophrenia suggested by whole-night deficits in slow and fast spindles | Q34268494 | ||
Neural synchrony indexes disordered perception and cognition in schizophrenia | Q34368405 | ||
Clinical development success rates for investigational drugs | Q34396786 | ||
Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders | Q34401694 | ||
Comparative study of human and mouse postsynaptic proteomes finds high compositional conservation and abundance differences for key synaptic proteins | Q34447339 | ||
Human iPSC neurons display activity-dependent neurotransmitter secretion: aberrant catecholamine levels in schizophrenia neurons | Q34469459 | ||
De novo mutations in schizophrenia implicate synaptic networks | Q34540372 | ||
Gene-environment interactions in psychiatry: joining forces with neuroscience | Q34540742 | ||
Abnormal medial prefrontal cortex resting-state connectivity in bipolar disorder and schizophrenia | Q35171332 | ||
A role for glia in the progression of Rett's syndrome | Q35712588 | ||
From circuits to behaviour in the amygdala | Q36045805 | ||
Schizophrenia is associated with elevated amphetamine-induced synaptic dopamine concentrations: evidence from a novel positron emission tomography method | Q36050571 | ||
Criteria of validity for animal models of psychiatric disorders: focus on anxiety disorders and depression. | Q36061657 | ||
Learning From Animal Models of Obsessive-Compulsive Disorder | Q36249163 | ||
Wild-type microglia do not reverse pathology in mouse models of Rett syndrome | Q36386922 | ||
Reduced sleep spindles and spindle coherence in schizophrenia: mechanisms of impaired memory consolidation? | Q36580050 | ||
Forward frontal fields: phylogeny and fundamental function | Q36984777 | ||
Cortical source estimates of gamma band amplitude and phase are different in schizophrenia | Q37086990 | ||
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior | Q37250051 | ||
A genome-wide linkage and association scan reveals novel loci for autism | Q37410600 | ||
Identifying essential cell types and circuits in autism spectrum disorders. | Q37500060 | ||
Coexpression networks implicate human midfetal deep cortical projection neurons in the pathogenesis of autism | Q37716254 | ||
Genetic architecture in autism spectrum disorder | Q37998609 | ||
Brain-mapping projects using the common marmoset | Q38255163 | ||
Genetic analysis of schizophrenia and bipolar disorder reveals polygenicity but also suggests new directions for molecular interrogation | Q38301816 | ||
Animal model of depression. I. Review of evidence: implications for research | Q40013217 | ||
Synaptic dysregulation in a human iPS cell model of mental disorders | Q41534293 | ||
Evolutionary conservation of the basal ganglia as a common vertebrate mechanism for action selection | Q42490452 | ||
Behavioural disorders induced by external globus pallidus dysfunction in primates: I. Behavioural study | Q42632778 | ||
Validation criteria for animal models of human mental disorders: learned helplessness as a paradigm case | Q43449419 | ||
Abnormalities of the left temporal lobe and thought disorder in schizophrenia. A quantitative magnetic resonance imaging study | Q44252090 | ||
Effect of riluzole on MK-801 and amphetamine-induced hyperlocomotion | Q44529350 | ||
Psychiatric endophenotypes and the development of valid animal models. | Q45920656 | ||
Pyramidal neurons derived from human pluripotent stem cells integrate efficiently into mouse brain circuits in vivo | Q48170047 | ||
Medicine. Brain disorders? Precisely | Q48199146 | ||
Wireless magnetothermal deep brain stimulation | Q48283798 | ||
Architectural subdivisions of medial and orbital frontal cortices in the marmoset monkey (Callithrix jacchus). | Q48717272 | ||
Striatal volume on magnetic resonance imaging and repetitive behaviors in autism | Q48866759 | ||
Impaired long-term depression in schizophrenia: a cathodal tDCS pilot study | Q48881014 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 979-88 | |
P577 | publication date | 2015-09-01 | |
P1433 | published in | Nature Medicine | Q1633234 |
P1476 | title | Modeling psychiatric disorders for developing effective treatments | |
P478 | volume | 21 |
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Q36851161 | Innovative approaches to bipolar disorder and its treatment |
Q30358363 | Marmosets: A Neuroscientific Model of Human Social Behavior. |
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