Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data

scientific article

Safety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

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P356DOI10.1136/BMJ.H4451
P3181OpenCitations bibliographic resource ID2719680
P932PMC publication ID4553205
P698PubMed publication ID26321114
P5875ResearchGate publication ID281352471

P50authorOliver J ZiffQ85578870
Richard P SteedsQ86925699
Deirdre A LaneQ87919930
Paulus KirchhofQ38326091
Jonathan N TownendQ43194026
Dipak KotechaQ47805074
Oliver ZiffQ56459980
Gregory LipQ60393087
P2093author name stringMonica Samra
Michael Griffith
P2860cites workDouble-blind placebo-controlled comparison of digoxin and xamoterol in chronic heart failure. The German and Austrian Xamoterol Study GroupQ69913635
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Digitalis: a dangerous drug in atrial fibrillation? An analysis of the SPORTIF III and V dataQ31111736
Digoxin associates with mortality in ESRD.Q34455390
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Association of serum digoxin concentration and outcomes in patients with heart failureQ73004928
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Are coronary patients at higher risk with digoxin therapy? An ongoing controversyQ77213439
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Declining public health burden of digoxin toxicity from 1991 to 2004Q80228560
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Digoxin in patients with atrial fibrillation and heart failure: A meta-analysisQ87164419
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Digitalis-associated cardiac mortality after myocardial infarctionQ93861589
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Pre-existing atrial fibrillation and risk of arterial thromboembolism and death following pneumonia: a population-based cohort studyQ34573036
ESC guidelines for the diagnosis and treatment of acute and chronic heart failure 2012: The Task Force for the Diagnosis and Treatment of Acute and Chronic Heart Failure 2012 of the European Society of Cardiology. Developed in collaboration with theQ34640762
Digoxin and mortality in atrial fibrillation: a prospective cohort studyQ34660772
Digoxin use in patients with atrial fibrillation and adverse cardiovascular outcomes: a retrospective analysis of the Rivaroxaban Once Daily Oral Direct Factor Xa Inhibition Compared with Vitamin K Antagonism for Prevention of Stroke and Embolism TrQ34668487
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Digoxin and risk of death in adults with atrial fibrillation: the ATRIA-CVRN studyQ35102218
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Increased mortality associated with digoxin in contemporary patients with atrial fibrillation: findings from the TREAT-AF studyQ35511302
Cost of an emerging epidemic: an economic analysis of atrial fibrillation in the UKQ35582163
Digitalis for treatment of congestive heart failure in patients in sinus rhythm: a systematic review and meta-analysisQ35752516
Controlling the risk of spurious findings from meta-regression.Q35782230
Digoxin Use and Subsequent Outcomes Among Patients in a Contemporary Atrial Fibrillation CohortQ35789263
Observational cohort study of the safety of digoxin use in women with heart failureQ35904187
Effects of digoxin at low serum concentrations on mortality and hospitalization in heart failure: a propensity-matched study of the DIG trialQ36776095
Lack of evidence of increased mortality among patients with atrial fibrillation taking digoxin: findings from post hoc propensity-matched analysis of the AFFIRM trialQ36860117
Should meta-analyses of interventions include observational studies in addition to randomized controlled trials? A critical examination of underlying principles.Q36915750
Effects of digoxin on morbidity and mortality in diastolic heart failure: the ancillary digitalis investigation group trialQ37066497
Digoxin and reduction of heart failure hospitalization in chronic systolic and diastolic heart failureQ37077866
Digoxin and reduction in mortality and hospitalization in geriatric heart failure: importance of low doses and low serum concentrationsQ37131733
Serum digoxin concentration and outcomes in women with heart failure: A bi-directional effect and a possible effect modification by ejection fractionQ37255465
Temporal relationship and prognostic significance of atrial fibrillation in heart failure patients with preserved ejection fraction: a community-based studyQ37543186
Digoxin use and lower 30-day all-cause readmission for Medicare beneficiaries hospitalized for heart failureQ37594550
Digoxin and 30-day all-cause hospital admission in older patients with chronic diastolic heart failureQ37599290
Interaction between digoxin and dronedarone in the PALLAS trialQ38421149
Distribution and risk profile of paroxysmal, persistent, and permanent atrial fibrillation in routine clinical practice: insight from the real-life global survey evaluating patients with atrial fibrillation international registryQ38943915
Digoxin treatment is associated with increased total and cardiovascular mortality in anticoagulated patients with atrial fibrillationQ41626846
Does digoxin increase the risk of ischemic stroke and mortality in atrial fibrillation? A nationwide population-based cohort studyQ41724146
An Introduction to Propensity Score Methods for Reducing the Effects of Confounding in Observational StudiesQ41962966
Digoxin Use and Heart Failure Outcomes: Results from the Valsartan Heart Failure Trial (Val‐HeFT)Q42871640
Guidelines for the management of atrial fibrillation: the Task Force for the Management of Atrial Fibrillation of the European Society of Cardiology (ESC).Q42923039
Digoxin therapy does not improve outcomes in patients with advanced heart failure on contemporary medical therapyQ43266268
The mortality risk associated with digitalis treatment after myocardial infarctionQ43607094
International subarachnoid aneurysm trial of neurosurgical clipping versus endovascular coiling: subgroup analysis of 278 elderly patientsQ43892890
A meta-analysis of the prognostic significance of atrial fibrillation in chronic heart failureQ43973759
???Q28267062
When 'digoxin use' is not the same as 'digoxin use': lessons from the AFFIRM trialQ43985351
International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trialQ44203470
Eplerenone in Patients with Systolic Heart Failure and Mild SymptomsQ44272913
Digitoxin-associated mortality in acute myocardial infarctionQ44362305
Effect of digitalis treatment on survival after acute myocardial infarctionQ44645984
The effects of digitalis on survival in high-risk patients with coronary artery disease. The Coronary Artery Surgery Study (CASS).Q44787981
Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validityQ44948737
Consistency of the beneficial effect of metoprolol succinate extended release across a wide range dose of angiotensin-converting enzyme inhibitors and digitalisQ45187902
The effect of gender on outcome in digitalis-treated heart failure patientsQ45283101
Digoxin significantly improves all-cause mortality in atrial fibrillation patients with severely reduced left ventricular systolic functionQ45365558
Relation of digoxin use in atrial fibrillation and the risk of all-cause mortality in patients ≥65 years of age with versus without heart failure.Q46095564
Effectiveness and safety of digoxin among contemporary adults with incident systolic heart failure.Q46548662
Digoxin and clinical outcomes in systolic heart failure patients on contemporary background heart failure therapyQ46960475
A cohort study of digoxin exposure and mortality in men with prostate cancerQ47797325
Economic outcomes of withdrawal of digoxin therapy in adult patients with stable congestive heart failureQ50597542
What is the economic value of digoxin therapy in congestive heart failure patients? Results from the DIG trialQ50732508
Outcomes of a contemporary sample of patients with atrial fibrillation taking digoxin: results from the AFBAR studyQ51031013
Digoxin in atrial fibrillation: report from the Stockholm Cohort study of Atrial Fibrillation (SCAF).Q51617706
In an empirical evaluation of the funnel plot, researchers could not visually identify publication biasQ51967379
Digoxin use and risk of mortality in hypertensive patients with atrial fibrillationQ53569088
The previous use of digoxin does not worsen early outcome of acute coronary syndromes: an analysis of the ARIAM Registry.Q54419973
Digitalis Use in Contemporary Clinical PracticeQ56534880
Digoxin in advanced heart failure patients: A question of rhythmQ58327554
Should digoxin be proscribed in elderly subjects in sinus rhythm free from heart failure? A population-based studyQ62113347
Exercise capacity and quality of life in the treatment of heart failureQ68427970
Digoxin therapy and mortality after myocardial infarction. Experience in the MILIS StudyQ68857763
Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. The Captopril-Digoxin Multicenter Research GroupQ69013550
A comparison of oral milrinone, digoxin, and their combination in the treatment of patients with chronic heart failureQ69487946
P275copyright licenseCreative Commons Attribution-NonCommercial 4.0 InternationalQ34179348
P407language of work or nameEnglishQ1860
P921main subjectheart failureQ181754
meta-analysisQ815382
atrial fibrillationQ815819
carbohydrateQ11358
digoxinQ422222
polycyclic compoundQ426145
systematic reviewQ1504425
cardiotonicQ2938102
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)h4451
P577publication date2015-08-30
P13046publication type of scholarly worksystematic reviewQ1504425
review articleQ7318358
P1433published inThe BMJQ546003
P1476titleSafety and efficacy of digoxin: systematic review and meta-analysis of observational and controlled trial data
P478volume351

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cites work (P2860)
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