Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options

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Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options is …
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P356DOI10.2147/OTT.S72202
P3181OpenCitations bibliographic resource ID4857154
P932PMC publication ID4548751
P698PubMed publication ID26316785

P2093author name stringBrett A Miles
Alok T Saini
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Human Merkel cell polyomavirus small T antigen is an oncoprotein targeting the 4E-BP1 translation regulatorQ24609227
Merkel cell polyomavirus and two previously unknown polyomaviruses are chronically shed from human skinQ24633468
T antigen mutations are a human tumor-specific signature for Merkel cell polyomavirusQ24645091
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Ultrastructural proof of polyomavirus in Merkel cell carcinoma tumour cells and its absence in small cell carcinoma of the lungQ30859864
Diagnostic biopsy does not commonly induce intratumoral CD8 T cell infiltration in Merkel cell carcinomaQ31080132
Merkel cell carcinoma: review of 22 cases with surgical, pathologic, and therapeutic considerationsQ33889184
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Palliative treatment for in-transit cutaneous metastases of Merkel cell carcinoma using surface-mold computer-optimized high-dose-rate brachytherapyQ34041326
A phase II trial of imatinib mesylate in merkel cell carcinoma (neuroendocrine carcinoma of the skin): A Southwest Oncology Group study (S0331)Q34088836
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Antibodies to Merkel Cell Polyomavirus T Antigen Oncoproteins Reflect Tumor Burden in Merkel Cell Carcinoma PatientsQ34267871
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Human polyomaviruses in disease and cancerQ34324891
TERT promoter mutations and gene amplification: promoting TERT expression in Merkel cell carcinomaQ34654382
Prognostic value of immune cell infiltration, tertiary lymphoid structures and PD-L1 expression in Merkel cell carcinomas.Q34733445
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Merkel cells and neurons keep in touchQ35034325
Primary Merkel Cell Carcinoma of the Submandibular Gland: When CK20 Status Complicates the DiagnosisQ35582720
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KIT receptor activation by autocrine and paracrine stem cell factor stimulates growth of merkel cell carcinoma in vitroQ39653324
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miRNA-34a underexpressed in Merkel cell polyomavirus-negative Merkel cell carcinoma.Q41607962
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Characterization of functional domains in the Merkel cell polyoma virus Large T antigenQ41744694
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Detection of mitotic figures and G2+ tumor nuclei with histone markers correlates with worse overall survival in patients with Merkel cell carcinomaQ35909855
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Merkel cell polyomavirus is frequently detected in korean patients with merkel cell carcinomaQ36871920
Creation of a Merkel cell polyomavirus small T antigen-expressing murine tumor model and a DNA vaccine targeting small T antigenQ37113061
Total spontaneous regression of advanced merkel cell carcinoma after biopsy: review and a new case.Q37118052
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Relationships among primary tumor size, number of involved nodes, and survival for 8044 cases of Merkel cell carcinomaQ37647879
The impact of (18)F-FDG PET-CT scanning for staging and management of Merkel cell carcinoma: results from Westmead Hospital, Sydney, AustraliaQ37677109
Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypesQ37713752
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Positive sentinel lymph node biopsy predicts local metastases during the course of disease in Merkel cell carcinoma.Q38080908
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Evidence-based management of primary and localized Merkel cell carcinoma: a reviewQ38119528
The important role of radiation treatment in the management of Merkel cell carcinomaQ38125223
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Diagnostic performance of fluorine-18-fluorodeoxyglucose positron emission tomography in patients with Merkel cell carcinoma: a systematic review and meta-analysis.Q38130160
Skin cancer in organ transplant recipients.Q38135213
Modern management of Merkel cell carcinomaQ38181869
Radiotherapy alone in patients with Merkel cell carcinoma: the Westmead Hospital experience of 41 patientsQ38264935
The role of adjuvant therapy in the management of head and neck merkel cell carcinoma: an analysis of 4815 patients.Q38283051
Neuroendocrine Merkel cell carcinoma is associated with mutations in key DNA repair, epigenetic and apoptosis pathways: a case-based study using targeted massively parallel sequencingQ38388671
Prevalence of human polyomaviruses in common and rare types of non-Merkel cell carcinoma skin cancerQ38402271
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpathogenesisQ372016
Merkel cell carcinomaQ1711744
head and neck squamous cell carcinomaQ18348812
P304page(s)2157-67
P577publication date2015-01-01
P1433published inOncoTargets and TherapyQ7092081
P1476titleMerkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options
P478volume8

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cites work (P2860)
Q37254490A 76 year old male with an unusual presentation of merkel cell carcinoma
Q41506356A thoracic vertebral localization of a metastasized cutaneous Merkel cell carcinoma: Case report and review of literature.
Q40100093Merkel Cell Carcinoma of the Head and Neck: Recommendations for Diagnostics and Treatment
Q58781846Merkel-cell carcinoma of the upper limb
Q90468644Nodal Merkel Cell Carcinoma in Head and Neck Lesions with an Unknown Primary: A Case Report in Light of the Literature
Q64046048Proceedings of the NASHNP Companion Meeting, March 18th, 2018, Vancouver, BC, Canada: Salivary Neuroendocrine Carcinoma-An Overview of a Rare Disease with an Emphasis on Determining Tumor Origin
Q38738614Systematic literature review of efficacy, safety and tolerability outcomes of chemotherapy regimens in patients with metastatic Merkel cell carcinoma
Q54960008Treatment of a Patient with Merkel Cell Skin Carcinoma Using Radiation Therapy - A Case Report.

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