Insulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: A meta-analysis of seven clinical trials

scientific article

Insulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: A meta-analysis of seven clinical trials is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814
meta-analysisQ815382

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P356DOI10.1016/J.NUMECD.2015.06.005
P8608Fatcat IDrelease_7rbvu4zffjh55inkoihveq7y4u
P3181OpenCitations bibliographic resource ID2951658
P698PubMed publication ID26232910
P5875ResearchGate publication ID279312816

P2093author name stringS Del Prato
M Niemeyer
M Diamant
D Russell-Jones
M-A Gall
P2860cites workClinical and socio-economic correlates of quality of life and treatment satisfaction in patients with type 2 diabetesQ46616745
Insulin degludec: four times lower pharmacodynamic variability than insulin glargine under steady-state conditions in type 1 diabetesQ49174475
Ultra-long-acting insulin degludec has a flat and stable glucose-lowering effect in type 2 diabetesQ84440683
Management of hyperglycemia in type 2 diabetes: a patient-centered approach: position statement of the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD).Q22241288
Ligand-controlled assembly of hexamers, dihexamers, and linear multihexamer structures by the engineered acylated insulin degludecQ27683621
Safety and efficacy of insulin detemir in clinical practice: 14-week follow-up data from type 1 and type 2 diabetes patients in the PREDICTIVE European cohortQ31101983
Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 1 diabetes (BEGIN Basal-Bolus Type 1): a phase 3, randomised, open-label, treat-to-target non-inferiority triaQ34269828
Insulin degludec, an ultra-longacting basal insulin, versus insulin glargine in basal-bolus treatment with mealtime insulin aspart in type 2 diabetes (BEGIN Basal-Bolus Type 2): a phase 3, randomised, open-label, treat-to-target non-inferiority triaQ34269834
Clinical Experience with Insulin Glargine in Type 1 DiabetesQ34296834
Self-reported non-severe hypoglycaemic events in EuropeQ34516215
Insulin degludec versus insulin glargine in type 1 and type 2 diabetes mellitus: a meta-analysis of endpoints in phase 3a trialsQ34726423
A comparison of health-related quality of life (health utility) between insulin degludec and insulin glargine: a meta-analysis of phase 3 trials.Q34981168
Insulin adherence behaviours and barriers in the multinational Global Attitudes of Patients and Physicians in Insulin Therapy studyQ36208628
Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long)Q36426912
Intermediate and long-acting insulins: a review of NPH insulin, insulin glargine and insulin detemirQ36682344
The efficacy and safety of insulin degludec given in variable once-daily dosing intervals compared with insulin glargine and insulin degludec dosed at the same time daily: a 26-week, randomized, open-label, parallel-group, treat-to-target trial in iQ36720304
Efficacy and safety of insulin degludec in a flexible dosing regimen vs insulin glargine in patients with type 1 diabetes (BEGIN: Flex T1): a 26-week randomized, treat-to-target trial with a 26-week extensionQ36730246
Low-volume insulin degludec 200 units/ml once daily improves glycemic control similarly to insulin glargine with a low risk of hypoglycemia in insulin-naive patients with type 2 diabetes: a 26-week, randomized, controlled, multinational, treat-to-taQ37106509
Hypoglycaemia risk with insulin degludec compared with insulin glargine in type 2 and type 1 diabetes: a pre-planned meta-analysis of phase 3 trialsQ37119978
Clinical inertia in people with type 2 diabetes: a retrospective cohort study of more than 80,000 peopleQ37278100
Addressing barriers to initiation of insulin in patients with type 2 diabetesQ37731624
Insulin degludec and insulin degludec/insulin aspart: a review of their use in the management of diabetes mellitusQ38101891
Design of the novel protraction mechanism of insulin degludec, an ultra-long-acting basal insulin.Q42240405
Patient-directed titration for achieving glycaemic goals using a once-daily basal insulin analogue: an assessment of two different fasting plasma glucose targets - the TITRATE studyQ42624054
Lower fasting blood glucose, glucose variability and nocturnal hypoglycaemia with glargine vs NPH basal insulin in subjects with Type 1 diabetes.Q42664001
Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetesQ44909481
P433issue10
P407language of work or nameEnglishQ1860
P921main subjecthypoglycemiaQ202758
insulin glargineQ417317
meta-analysisQ815382
preproinsulinQ7240673
P304page(s)898-905
P577publication date2015-10-01
P1433published inNutrition, Metabolism, and Cardiovascular DiseasesQ2734631
P1476titleInsulin degludec results in lower rates of nocturnal hypoglycaemia and fasting plasma glucose vs. insulin glargine: A meta-analysis of seven clinical trials
P478volume25

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cites work (P2860)
Q47176512Antihyperglycemic Agent Therapy for Adult Patients with Type 2 Diabetes Mellitus 2017: A Position Statement of the Korean Diabetes Association
Q47094226Antihyperglycemic agent therapy for adult patients with type 2 diabetes mellitus 2017: a position statement of the Korean Diabetes Association
Q91787082Clinical implications of prolonged hyperglycaemia before basal insulin initiation in type 2 diabetes patients: An electronic medical record database analysis
Q89230569Clinical outcomes in real-world patients with type 2 diabetes switching from first- to second-generation basal insulin analogues: Comparative effectiveness of insulin glargine 300 units/mL and insulin degludec in the DELIVER D+ cohort study
Q52605864Efficacy and Safety of Insulin Glargine 300 U/mL versus 100 U/mL in Diabetes Mellitus: A Comprehensive Review of the Literature.
Q90456535Exposure to insulin degludec during pregnancy: report of a small series and review of the literature
Q38916256Insulin degludec + liraglutide: a complementary combination
Q48306120Insulin degludec in the first trimester of pregnancy: Report of two cases.
Q28074690Insulin glargine 300 U/mL in the management of diabetes: clinical utility and patient perspectives
Q57026285Management of Hyperglycemia in Type 2 Diabetes, 2018. A Consensus Report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Q56979722Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)
Q64072341Optimal regulation of blood glucose level in Type I diabetes using insulin and glucagon
Q47259503Real-world evidence on clinical and economic outcomes of switching to insulin glargine 300 Units/mL vs other basal insulins in patients with type 2 diabetes on basal insulin.
Q37538487Real-world medication persistence and outcomes associated with basal insulin and glucagon-like peptide 1 receptor agonist free-dose combination therapy in patients with type 2 diabetes in the US.
Q90402553Second-Generation Insulin Analogues - a Review of Recent Real-World Data and Forthcoming Head-to-Head Comparisons
Q93167299Successful Outcomes with Insulin Degludec in Pregnancy: A Case Series
Q90359481Suitable Use of Injectable Agents to Overcome Hypoglycemia Risk, Barriers, and Clinical Inertia in Community-Dwelling Older Adults with Type 2 Diabetes Mellitus
Q57281197Time-action profiles of insulin degludec in healthy dogs and its effects on glycemic control in diabetic dogs
Q99560824Understanding the Clinical Profile of Insulin Degludec, the Latest Basal Insulin Approved for Use in Canada: a Narrative Review

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