Progress toward curing HIV infection with hematopoietic cell transplantation

scientific article (publication date: 2015)

Progress toward curing HIV infection with hematopoietic cell transplantation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2147/SCCAA.S56050
P932PMC publication ID4524463
P698PubMed publication ID26251620

P50authorElizabeth J ShpallQ87373605
Stephen SpellmanQ111077182
John C. BurnettQ50421173
P2093author name stringJohn J Rossi
Loren Gragert
Joanne Kurtzberg
Pamela Clark
Sue Armitage
Shirley Li
Haitang Li
Jonathan A Gutman
Sergio Querol
Lawrence D Petz
Richard Tonai
Donna M Regan
Milena Bakalinskaya
P2860cites workFoamy virus vectors for HIV gene therapyQ26859020
More on shift of HIV tropism in stem-cell transplantation with CCR5 delta32/delta32 mutation.Q51074921
A phase I trial of autologous CD34+ hematopoietic progenitor cells transduced with an anti-HIV ribozymeQ73022564
Haplo-cord transplantation using CD34+ cells from a third-party donor to speed engraftment in high-risk patients with hematologic disordersQ85637058
Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cellsQ37401812
Alternative haematopoietic stem cell sources for transplantation: place of umbilical cord bloodQ37435417
CCR5 as a natural and modulated target for inhibition of HIV.Q37566693
Current status and challenges of antiretroviral research and therapyQ37657867
Genetic modification of hematopoietic stem cells as a therapy for HIV/AIDS.Q37666741
Alternative donor transplantation--"mixing and matching": the role of combined cord blood and haplo-identical donor transplantation (haplo-cord SCT) as a treatment strategy for patients lacking standard donors?Q38350274
Short communication: Efficiently inhibiting HIV-1 replication by a prototype foamy virus vector expressing novel H1 promoter-driven short hairpin RNAsQ38926383
CCR5 Δ32 homozygous cord blood allogeneic transplantation in a patient with HIV: a case reportQ38978741
Preclinical safety and efficacy of an anti-HIV-1 lentiviral vector containing a short hairpin RNA to CCR5 and the C46 fusion inhibitorQ39600778
Stable human immunodeficiency virus type 1 (HIV-1) resistance in transformed CD4+ monocytic cells treated with multitargeting HIV-1 antisense sequences incorporated into U1 snRNA.Q39879519
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposureQ41212897
Safety and efficacy of a tCD25 preselective combination anti-HIV lentiviral vector in human hematopoietic stem and progenitor cellsQ41591165
Shift of HIV tropism in stem-cell transplantation with CCR5 Delta32 mutationQ43806342
Single cord blood combined with HLA-mismatched third party donor cells: comparable results to matched unrelated donor transplantation in high-risk patients with hematologic disordersQ43978870
Immune reconstitution after combined haploidentical and umbilical cord blood transplantQ45142789
A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children.Q45748774
Analysis of CCR5-Delta 32 and CCR2-V64I polymorphisms in a cohort of Spanish HCV patients using real-time polymerase chain reaction and fluorescence resonance energy transfer technologiesQ47257043
HLA match likelihoods for hematopoietic stem-cell grafts in the U.S. registryQ50109403
Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman PrimatesQ27318042
Understanding HIV latency: the road to an HIV cureQ28085296
Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIVQ28235281
Targeted genome engineering in human cells with the Cas9 RNA-guided endonucleaseQ28284509
Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1Q28290118
CCR5 gene disruption via lentiviral vectors expressing Cas9 and single guided RNA renders cells resistant to HIV-1 infectionQ28542878
Development of Hematopoietic Stem Cell Based Gene Therapy for HIV-1 Infection: Considerations for Proof of Concept Studies and Translation to Standard Medical PracticeQ29036869
Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infectionQ29614956
Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantationQ29615068
Identification and frequency of CCR5Δ32/Δ32 HIV-resistant cord blood units from Houston area hospitals.Q33615123
TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicityQ33698693
Seamless modification of wild-type induced pluripotent stem cells to the natural CCR5Δ32 mutation confers resistance to HIV infectionQ33854184
Ribozyme therapy for HIV infectionQ34062644
RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphomaQ34121209
Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivoQ34124290
A novel TALE nuclease scaffold enables high genome editing activity in combination with low toxicity.Q34205743
Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5Q34325074
Global distribution of the CCR5 gene 32-basepair deletion.Q34425080
Towards an HIV cure: a global scientific strategyQ34640562
HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cellsQ34672568
Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9Q34727851
Stable transduction of quiescent CD34(+)CD38(-) human hematopoietic cells by HIV-1-based lentiviral vectorsQ35064224
Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivoQ35182775
Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutationsQ35521811
Reduced-intensity conditioning with combined haploidentical and cord blood transplantation results in rapid engraftment, low GVHD, and durable remissionsQ35608181
Precision genome engineering with programmable DNA-nicking enzymesQ36093894
Hematopoietic cell transplantation with cord blood for cure of HIV infectionsQ36295174
Stimulation of HIV-1-specific cytolytic T lymphocytes facilitates elimination of latent viral reservoir after virus reactivationQ36409885
Antiviral effects of autologous CD4 T cells genetically modified with a conditionally replicating lentiviral vector expressing long antisense to HIVQ36654098
Umbilical cord blood transplantation supported by third-party donor cells: rationale, results, and applicationsQ36746512
HIV-1 and T cell dynamics after interruption of highly active antiretroviral therapy (HAART) in patients with a history of sustained viral suppressionQ36781531
Stable gene transfer of CCR5 and CXCR4 siRNAs by sleeping beauty transposon system to confer HIV-1 resistanceQ36870325
Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleasesQ36915157
Preclinical in vivo evaluation of the safety of a multi-shRNA-based gene therapy against HIV-1Q37256335
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
P304page(s)109-116
P577publication date2015-07-28
P1433published inStem Cells and Cloning: advances and applicationsQ15817523
P1476titleProgress toward curing HIV infection with hematopoietic cell transplantation
P478volume8

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cites work (P2860)
Q50147823Analysis of the Spanish CCR5-∆32 inventory of cord blood units: lower cell counts in homozygous donors.
Q40128097Coexpression Analysis of Transcriptome on AIDS and Other Human Disease Pathways by Canonical Correlation Analysis.
Q54854526Insulators to Improve the Safety of Retroviral Vectors for HIV Gene Therapy.
Q37661792Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation
Q38409791Propagating Humanized BLT Mice for the Study of Human Immunology and Immunotherapy
Q92706205Risks and Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation for Hematologic Malignancies in Patients with HIV Infection