The ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach

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The ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach is …
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scholarly articleQ13442814

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P356DOI10.2217/FMB.13.43
P932PMC publication ID3852439
P698PubMed publication ID23701330

P2093author name stringD Scott Merrell
Oscar Q Pich
P2860cites workThe role of the Ferric Uptake Regulator (Fur) in regulation of Helicobacter pylori iron uptake.Q54540507
Infection with Helicobacter pylori strains possessing cagA is associated with an increased risk of developing adenocarcinoma of the stomachQ72220074
The reductive metabolism of metronidazole and ronidazole by aerobic liver microsomesQ72856911
Relationship between the mucosal production of reactive oxygen radicals and density of Helicobacter pylori in patients with duodenal ulcerQ73208557
Ammonia, hydrogen peroxide, and monochloramine retard gastric epithelial restoration in rabbit cultured cell modelQ73343669
Increased inflammatory responses of persons of blood group O to Helicobacter pyloriQ73642682
Prevalence and pattern of Helicobacter pylori gastritis in the gastric cardiaQ73943226
Iron-deficiency anemia associated with Helicobacter pylori gastritisQ74005434
Iron acquisition and virulence in Helicobacter pylori: a major role for FeoB, a high-affinity ferrous iron transporterQ74130037
The Fur repressor controls transcription of iron-activated and -repressed genes in Helicobacter pyloriQ77748405
Autoregulation of Helicobacter pylori Fur revealed by functional analysis of the iron-binding siteQ78487583
Enhanced Fe ion-uptake activity in Helicobacter pylori strains isolated from patients with iron-deficiency anemiaQ80498365
The effect of Helicobacter pylori infection and dietary iron deficiency on host iron homeostasis: a study in miceQ81174072
FecA1, a bacterial iron transporter, determines the survival of Helicobacter pylori in the stomachQ83242574
The frpB1 gene of Helicobacter pylori is regulated by iron and encodes a membrane protein capable of binding haem and haemoglobinQ83747210
Two amino acids mutation of ferric uptake regulator determines Helicobacter pylori resistance to metronidazoleQ84343599
The complete genome sequence of the gastric pathogen Helicobacter pyloriQ22122352
Identification of Helicobacter pylori genes that contribute to stomach colonizationQ24678679
Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative nicheQ27317084
The Bacillus subtilis iron-sparing response is mediated by a Fur-regulated small RNA and three small, basic proteinsQ27443131
Structure and regulon of Campylobacter jejuni ferric uptake regulator Fur define apo-Fur regulationQ27679507
Current concepts in the management of Helicobacter pylori infection--the Maastricht 2-2000 Consensus ReportQ28203195
Helicobacter pylori infection induces gastric cancer in mongolian gerbilsQ28280923
Helicobacter pylori gamma-glutamyl transpeptidase is a pathogenic factor in the development of peptic ulcer diseaseQ28484809
A single nucleotide change affects fur-dependent regulation of sodB in H. pyloriQ29346540
Iron-responsive regulation of the Helicobacter pylori iron-cofactored superoxide dismutase SodB is mediated by FurQ29346551
Iron and fur regulation in Vibrio cholerae and the role of fur in virulenceQ29346621
Essential role of Helicobacter pylori gamma-glutamyltranspeptidase for the colonization of the gastric mucosa of miceQ30670335
Gastric mucosal damage caused by monochloramine in the rat and protective effect of taurine: endoscopic observation through gastric fistulaQ30860246
Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surfaceQ31010231
Helicobacter pylori ribBA-mediated riboflavin production is involved in iron acquisition.Q32084487
Comparative proteomic analysis of Helicobacter pylori strains associated with iron deficiency anemiaQ33231322
Does Helicobacter pylori infection play a role in iron deficiency anemia? A meta-analysisQ33530352
Iron acquisition by Helicobacter pylori: importance of human lactoferrinQ33601247
Risk for gastric cancer in people with CagA positive or CagA negative Helicobacter pylori infectionQ33617838
Chemotaxis plays multiple roles during Helicobacter pylori animal infectionQ33796254
Iron and oxidative stress in bacteriaQ33808433
Unique host iron utilization mechanisms of Helicobacter pylori revealed with iron-deficient chemically defined mediaQ33826092
Activation of beta-catenin by carcinogenic Helicobacter pyloriQ33906825
Vacuolating cytotoxin of Helicobacter pylori plays a role during colonization in a mouse model of infectionQ34005878
PerR controls oxidative stress resistance and iron storage proteins and is required for virulence in Staphylococcus aureusQ34007737
Superoxide dismutase-deficient mutants of Helicobacter pylori are hypersensitive to oxidative stress and defective in host colonizationQ34008070
gamma-Glutamyltransferase is a Helicobacter pylori virulence factor but is not essential for colonizationQ34008157
The Helicobacter pylori homologue of the ferric uptake regulator is involved in acid resistanceQ34116920
Active transport of iron and siderophore antibioticsQ34122249
In vitro analysis of protein-operator interactions of the NikR and fur metal-responsive regulators of coregulated genes in Helicobacter pyloriQ34124294
Expression of multidrug resistance efflux pump gene norA is iron responsive in Staphylococcus aureusQ34135493
Molecular hydrogen as an energy source for Helicobacter pyloriQ34161967
Helicobacter pylori gamma-glutamyltranspeptidase upregulates COX-2 and EGF-related peptide expression in human gastric cellsQ40592348
Fur activates expression of the 2-oxoglutarate oxidoreductase genes (oorDABC) in Helicobacter pyloriQ41173367
Reduction of iron by extracellular iron reductases: implications for microbial iron acquisitionQ41471733
Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric diseaseQ41814225
The complete genome sequence of Helicobacter pylori strain G27.Q41863855
Bacillus cereus Fur regulates iron metabolism and is required for full virulence.Q42042202
Deletion of the ferric uptake regulator Fur impairs the in vitro growth and virulence of Actinobacillus pleuropneumoniaeQ42240444
Detailed in vivo analysis of the role of Helicobacter pylori Fur in colonization and diseaseQ42738155
The Helicobacter pylori Ferric Uptake Regulator (Fur) is essential for growth under sodium chloride stressQ42779207
Growth phase and metal-dependent transcriptional regulation of the fecA genes in Helicobacter pylori.Q43127669
Histoplasma capsulatum secreted gamma-glutamyltransferase reduces iron by generating an efficient ferric reductantQ43249708
A possible relation of the Helicobacter pylori pfr gene to iron deficiency anemia?Q43591916
Iron deficiency and Helicobacter pylori infection in the United StatesQ44211253
Differential regulation of amidase- and formamidase-mediated ammonia production by the Helicobacter pylori fur repressorQ44260464
Differences in Helicobacter pylori associated gastritis in the antrum and body of the stomachQ44448651
L-Serine, D- and L-proline and alanine as respiratory substrates of Helicobacter pylori: correlation between in vitro and in vivo amino acid levelsQ44540622
Heightened inflammatory response and cytokine expression in vivo to cagA+ Helicobacter pylori strains.Q44755796
Polymorphism of the Helicobacter pylori feoB gene in Korea: a possible relation with iron-deficiency anemia?Q44990785
The gene frpB2 of Helicobacter pylori encodes an hemoglobin-binding protein involved in iron acquisitionQ45244653
Helicobacter pylori cag-type IV secretion system facilitates corpus colonization to induce precancerous conditions in Mongolian gerbilsQ46485028
Possible involvement of put A gene in Helicobacter pylori colonization in the stomach and motilityQ46698610
Helicobacter pylori, anemia, and iron deficiency: relationships explored among Alaska native childrenQ46977011
Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori.Q47261526
An anti-repression Fur operator upstream of the promoter is required for iron-mediated transcriptional autoregulation in Helicobacter pyloriQ47380400
Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expressionQ47852209
Identification of iron-regulated genes of Helicobacter pylori by a modified fur titration assay (FURTA-Hp).Q47878098
Structural, functional and mutational analysis of the pfr gene encoding a ferritin from Helicobacter pyloriQ48014930
Characterization of the NifU and NifS Fe-S cluster formation proteins essential for viability in Helicobacter pylori.Q52541821
Metabolism of glutamine and glutathione via gamma-glutamyltranspeptidase and glutamate transport in Helicobacter pylori: possible significance in the pathophysiology of the organism.Q54444586
A global investigation of the Bacillus subtilis iron-sparing response identifies major changes in metabolismQ34258592
Iron deficiency anaemia can be improved after eradication of Helicobacter pyloriQ34308413
Oxygen reactivity of PutA from Helicobacter species and proline-linked oxidative stressQ34353959
Vitamin B6 is required for full motility and virulence in Helicobacter pyloriQ34398722
Gastric Helicobacter infection induces iron deficiency in the INS-GAS mouseQ34491166
The future of gastric cancer preventionQ34546719
Helicobacter pylori-related iron deficiency anemia: a reviewQ34609633
Helicobacter pylori and atrophic gastritis: importance of the cagA statusQ34718764
The stomach and iron deficiency anaemia: a forgotten link.Q35151810
The quest for a vaccine against Helicobacter pylori: how to move from mouse to man?Q35157693
Microbial ferric iron reductasesQ35164044
Iron acquisition and regulation in Campylobacter jejuniQ35277029
Iron-repressible outer membrane proteins of Helicobacter pylori involved in heme uptakeQ35446423
Disruption of putative regulatory loci in Listeria monocytogenes demonstrates a significant role for Fur and PerR in virulenceQ35549748
Metal import through microbial membranesQ35626594
Clearance of Helicobacter pylori infection through immunization: the site of T cell activation contributes to vaccine efficacyQ35710205
Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strainsQ35841141
Helicobacter pylori eradication has the potential to prevent gastric cancer: a state-of-the-art critiqueQ36243482
Riboflavin biosynthesis is associated with assimilatory ferric reduction and iron acquisition by Campylobacter jejuniQ36313529
Growth phase-dependent response of Helicobacter pylori to iron starvationQ36374743
CagA-producing Helicobacter pylori and increased risk of gastric cancer: a nested case-control study in KoreaQ36612263
Characterization of a Helicobacter hepaticus putA mutant strain in host colonization and oxidative stressQ36747237
This is not your mother's repressor: the complex role of fur in pathogenesisQ37256551
Regulation of the Helicobacter pylori Fe-S cluster synthesis protein NifS by iron, oxidative stress conditions, and fur.Q38311812
Iron and pH homeostasis intersect at the level of Fur regulation in the gastric pathogen Helicobacter pyloriQ38317457
Regulation of ferritin-mediated cytoplasmic iron storage by the ferric uptake regulator homolog (Fur) of Helicobacter pyloriQ39501015
Potential role for extracellular glutathione-dependent ferric reductase in utilization of environmental and host ferric compounds by Histoplasma capsulatumQ39523022
Iron-dependent transcription of the frpB gene of Helicobacter pylori is controlled by the Fur repressor protein.Q39526674
Detailed analysis of Helicobacter pylori Fur-regulated promoters reveals a Fur box core sequence and novel Fur-regulated genesQ39628605
Essential role of ferritin Pfr in Helicobacter pylori iron metabolism and gastric colonizationQ39655662
pH-regulated gene expression of the gastric pathogen Helicobacter pyloriQ39755125
Colonization of gnotobiotic piglets by Helicobacter pylori deficient in two flagellin genes.Q39825323
Identification, characterization, and immunogenicity of the lactoferrin-binding protein from Helicobacter pyloriQ39833169
Helicobacter pylori CagA phosphorylation-independent function in epithelial proliferation and inflammationQ39893265
Acid-responsive gene induction of ammonia-producing enzymes in Helicobacter pylori is mediated via a metal-responsive repressor cascade.Q40470019
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectHelicobacter pyloriQ180556
Helicobacter pylori infectious diseaseQ4497153
P304page(s)725-38
P577publication date2013-06-01
P1433published inFuture MicrobiologyQ15759961
P1476titleThe ferric uptake regulator of Helicobacter pylori: a critical player in the battle for iron and colonization of the stomach
P478volume8

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cites work (P2860)
Q30249014An updated systematic review and meta-analysis on the association between Helicobacter pylori infection and iron deficiency anemia
Q42831834Control of gene expression in Helicobacter pylori using the Tet repressor
Q37591501Diet, microbial virulence, and Helicobacter pylori-induced gastric cancer
Q37424965Dietary Composition Influences Incidence of Helicobacter pylori-Induced Iron Deficiency Anemia and Gastric Ulceration
Q36294894Expansion of the tetracycline-dependent regulation toolbox for Helicobacter pylori
Q34002548Functional genomics of Lactobacillus casei establishment in the gut
Q38819899Gene Expression Profiling of Transcription Factors of Helicobacter pylori under Different Environmental Conditions.
Q92726074Global transcriptomic analyses of Salmonella enterica in Iron-depleted and Iron-rich growth conditions
Q55314807Helicobacter pylori genetic diversification in the Mongolian gerbil model.
Q34472442Interplay between iron homeostasis and virulence: Fur and RyhB as major regulators of bacterial pathogenicity.
Q53698735No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.
Q41996723Pan-genomic analyses identify key Helicobacter pylori pathogenic loci modified by carcinogenic host microenvironments.
Q47553329Reply to "Iron Overload and Hepatitis C Virus Infection".
Q33729993Site-specific His/Asp phosphoproteomic analysis of prokaryotes reveals putative targets for drug resistance.
Q40829117The CrdRS two-component system in Helicobacter pylori responds to nitrosative stress.
Q64116077Thioredoxin H (TrxH) contributes to adversity adaptation and pathogenicity of Edwardsiella piscicida
Q92144864Transcriptional response to metal starvation in the emerging pathogen Mycoplasma genitalium is mediated by Fur-dependent and -independent regulatory pathways
Q30393807Use of Random and Site-Directed Mutagenesis to Probe Protein Structure-Function Relationships: Applied Techniques in the Study of Helicobacter pylori

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