review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Tomás Gutierrez | Q82413023 |
P2093 | author name string | Thomas Simmen | |
P2860 | cites work | Cathepsin D maturation and its stimulatory effect on metastasis are prevented by addition of KDEL retention signal | Q72306301 |
Folding of VSV G protein: sequential interaction with BiP and calnexin | Q72752117 | ||
Calreticulin and calreticulin fragments are endothelial cell inhibitors that suppress tumor growth | Q73023343 | ||
Secretory pathway kinetics and in vivo analysis of protein traffic from the Golgi complex to the cell surface | Q73319946 | ||
Role of Sec61alpha in the regulated transfer of the ribosome-nascent chain complex from the signal recognition particle to the translocation channel | Q73453521 | ||
CD91: a receptor for heat shock protein gp96 | Q73615235 | ||
Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death | Q73615868 | ||
Sulfhydryl regulation of L-selectin shedding: phenylarsine oxide promotes activation-independent L-selectin shedding from leukocytes | Q73644500 | ||
Expression and prognostic significance of prothymosin-alpha and ERp57 in human gastric cancer | Q79450472 | ||
Cell surface expression of the stress response chaperone GRP78 enables tumor targeting by circulating ligands | Q80591503 | ||
Calreticulin is a B cell molecular target in some gastrointestinal malignancies | Q82323331 | ||
The localization of the ER retrieval sequence for the calcium pump SERCA1 | Q83764086 | ||
Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma | Q84742764 | ||
Autophagy-dependent suppression of cancer immunogenicity and effector mechanisms of innate and adaptive immunity | Q42215130 | ||
Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress. | Q42594025 | ||
Rer1p regulates the ER retention of immature rhodopsin and modulates its intracellular trafficking | Q42771550 | ||
Calreticulin surface exposure is abrogated in cells lacking, chaperone-mediated autophagy-essential gene, LAMP2A. | Q42911694 | ||
A link between ER tethering and COP-I vesicle uncoating | Q43275787 | ||
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin | Q43566795 | ||
Sustained integrin ligation involves extracellular free sulfhydryls and enzymatically catalyzed disulfide exchange | Q44142827 | ||
The role of MTJ-1 in cell surface translocation of GRP78, a receptor for alpha 2-macroglobulin-dependent signaling | Q44592099 | ||
The endoplasmic reticulum stress markers GRP78 and CHOP predict disease-free survival and responsiveness to chemotherapy in breast cancer | Q44809051 | ||
The rate of bulk flow from the endoplasmic reticulum to the cell surface | Q45345734 | ||
Evidence for a COP-I-independent transport route from the Golgi complex to the endoplasmic reticulum | Q45345946 | ||
Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network | Q46134516 | ||
Saturation of the endoplasmic reticulum retention machinery reveals anterograde bulk flow | Q52864915 | ||
AB5 subtilase cytotoxin inactivates the endoplasmic reticulum chaperone BiP. | Q53595113 | ||
Rab6A and Rab6A' GTPases play non-overlapping roles in membrane trafficking. | Q53632605 | ||
The conformation of calreticulin is influenced by the endoplasmic reticulum luminal environment. | Q54049232 | ||
Cell surface expression of the endoplasmic reticular heat shock protein gp96 is phylogenetically conserved | Q56902083 | ||
Tumor-specific cell surface expression of the -KDEL containing endoplasmic reticular heat shock protein gp96 | Q60021885 | ||
Different sorting of Lys-Asp-Glu-Leu proteins in rat liver | Q67848551 | ||
Localization of protein disulfide isomerase on plasma membranes of rat exocrine pancreatic cells | Q68149615 | ||
Depletion of intracellular calcium stores by calcium ionophore A23187 induces the genes for glucose-regulated proteins in hamster fibroblasts | Q70355655 | ||
Localization of protein disulfide isomerase to the external surface of the platelet plasma membrane | Q72030923 | ||
Coupling of coat assembly and vesicle budding to packaging of putative cargo receptors | Q22008843 | ||
Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 | Q24293643 | ||
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activation | Q24298757 | ||
GRP78 and Raf-1 cooperatively confer resistance to endoplasmic reticulum stress-induced apoptosis | Q24302321 | ||
Galectin-9 binding to cell surface protein disulfide isomerase regulates the redox environment to enhance T-cell migration and HIV entry | Q24306482 | ||
A human homologue of the yeast HDEL receptor | Q24310841 | ||
Implication of ZW10 in membrane trafficking between the endoplasmic reticulum and Golgi | Q24317648 | ||
Calreticulin is the dominant pro-phagocytic signal on multiple human cancers and is counterbalanced by CD47 | Q24561405 | ||
Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of "ER-resident" molecular chaperones | Q24564774 | ||
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma | Q24598483 | ||
Endoplasmic reticulum stress sensing in the unfolded protein response | Q36626672 | ||
Affinity panning of a library of peptides displayed on bacteriophages reveals the binding specificity of BiP. | Q36721098 | ||
The subcellular distribution of calnexin is mediated by PACS-2 | Q36739888 | ||
Retrograde traffic from the Golgi to the endoplasmic reticulum | Q36865153 | ||
Structure and function of major histocompatibility complex class I antigens | Q37012868 | ||
Re-Examination of CD91 Function in GRP94 (Glycoprotein 96) Surface Binding, Uptake, and Peptide Cross-Presentation | Q37029458 | ||
Pten null prostate tumorigenesis and AKT activation are blocked by targeted knockout of ER chaperone GRP78/BiP in prostate epithelium | Q37039595 | ||
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death | Q37133168 | ||
Pattern recognition receptors in the immune response against dying cells | Q37191778 | ||
Dynamic regulation of Ero1α and peroxiredoxin 4 localization in the secretory pathway | Q37226153 | ||
The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies | Q37285838 | ||
Hypoxia signalling through mTOR and the unfolded protein response in cancer | Q37290935 | ||
The quality control of MHC class I peptide loading | Q37300625 | ||
Danger signalling during cancer cell death: origins, plasticity and regulation. | Q37381745 | ||
Inhibition of tumor progression by suppression of stress protein GRP78/BiP induction in fibrosarcoma B/C10ME. | Q37433487 | ||
Localisation and trafficking of Toll-like receptors: an important mode of regulation. | Q37671100 | ||
Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase | Q37726811 | ||
Protein sorting receptors in the early secretory pathway | Q37763713 | ||
GRP78 signaling hub a receptor for targeted tumor therapy | Q37784290 | ||
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death | Q24620548 | ||
Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells | Q24648786 | ||
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells | Q24670661 | ||
Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44 | Q24672358 | ||
Interaction of murine BiP/GRP78 with the DnaJ homologue MTJ1 | Q24681842 | ||
GRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulum | Q26860153 | ||
Structures and mechanisms of vesicle coat components and multisubunit tethering complexes | Q27009146 | ||
Orchestration of secretory protein folding by ER chaperones | Q27013551 | ||
Molecular Basis for Recognition of Dilysine Trafficking Motifs by COPI | Q27675211 | ||
Rules for the recognition of dilysine retrieval motifs by coatomer | Q27676769 | ||
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of HER2 | Q27679845 | ||
N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin. | Q27863759 | ||
ERD2, a yeast gene required for the receptor-mediated retrieval of luminal ER proteins from the secretory pathway | Q27935834 | ||
Rab2 is essential for the maturation of pre-Golgi intermediates | Q28118777 | ||
Aspirin and salicylate bind to immunoglobulin heavy chain binding protein (BiP) and inhibit its ATPase activity in human fibroblasts | Q28191188 | ||
Protein quality control, retention, and degradation at the endoplasmic reticulum | Q28252854 | ||
Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival | Q28255981 | ||
Dominant inhibitory mutants of ARF1 block endoplasmic reticulum to Golgi transport and trigger disassembly of the Golgi apparatus | Q28258751 | ||
Peptide-dependent stimulation of the ATPase activity of the molecular chaperone BiP is the result of conversion of oligomers to active monomers | Q28269985 | ||
The ARF1 GTPase-activating protein: zinc finger motif and Golgi complex localization | Q28271461 | ||
Calreticulin exposure dictates the immunogenicity of cancer cell death | Q28280438 | ||
Rab18 and Rab43 have key roles in ER-Golgi trafficking | Q28288974 | ||
Cancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 production | Q28534981 | ||
The cellular oxygen tension regulates expression of the endoplasmic oxidoreductase ERO1‐Lα | Q28571513 | ||
Coatomer interaction with di-lysine endoplasmic reticulum retention motifs | Q28609806 | ||
Extracellular heat shock protein HSP90beta secreted by MG63 osteosarcoma cells inhibits activation of latent TGF-beta1 | Q28854589 | ||
Cell-surface calreticulin initiates clearance of viable or apoptotic cells through trans-activation of LRP on the phagocyte | Q29615441 | ||
The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
Autophagy-dependent anticancer immune responses induced by chemotherapeutic agents in mice | Q29615615 | ||
Relationship between HLA class I antigen processing machinery component expression and the clinicopathologic characteristics of bladder carcinomas | Q30425423 | ||
ER Import Sites and Their Relationship to ER Exit Sites: A New Model for Bidirectional ER-Golgi Transport in Higher Plants | Q30523967 | ||
A Fenton reaction at the endoplasmic reticulum is involved in the redox control of hypoxia-inducible gene expression | Q30828833 | ||
Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential | Q33278631 | ||
Beyond receptor expression levels: the relevance of target accessibility in ligand-directed pharmacodelivery systems | Q33343814 | ||
Cellular mechanisms of membrane protein folding | Q33624056 | ||
Mouse proteome analysis | Q33677663 | ||
The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery? | Q33717397 | ||
Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP. | Q33832578 | ||
Secretory protein trafficking and organelle dynamics in living cells | Q33921421 | ||
Calcium, a signaling molecule in the endoplasmic reticulum? | Q33953214 | ||
Increasing melanoma cell death using inhibitors of protein disulfide isomerases to abrogate survival responses to endoplasmic reticulum stress. | Q34051194 | ||
Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis. | Q34118737 | ||
Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy | Q34284930 | ||
Ero1-L alpha plays a key role in a HIF-1-mediated pathway to improve disulfide bond formation and VEGF secretion under hypoxia: implication for cancer | Q34375617 | ||
A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell death | Q34437578 | ||
Membrane protein retrieval from the Golgi apparatus to the endoplasmic reticulum (ER): characterization of the RER1 gene product as a component involved in ER localization of Sec12p | Q34452783 | ||
Dynamic retention of Ero1alpha and Ero1beta in the endoplasmic reticulum by interactions with PDI and ERp44. | Q34522219 | ||
Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA. | Q34533508 | ||
Calreticulin expression in infiltrating ductal breast carcinomas: relationships with disease progression and humoral immune responses. | Q34555318 | ||
Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib. | Q34618673 | ||
Efficient export of the vesicular stomatitis virus G protein from the endoplasmic reticulum requires a signal in the cytoplasmic tail that includes both tyrosine-based and di-acidic motifs | Q34664121 | ||
Inside, outside, upside down: damage-associated molecular-pattern molecules (DAMPs) and redox | Q34685501 | ||
The inflammatory response to cell death | Q34718276 | ||
The human PDI family: versatility packed into a single fold. | Q34727849 | ||
Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK). | Q35111066 | ||
Cotranslational folding inhibits translocation from within the ribosome-Sec61 translocon complex | Q35153371 | ||
Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling | Q35692042 | ||
ER stress activates the NLRP3 inflammasome via an UPR-independent pathway | Q35723848 | ||
The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer | Q36015748 | ||
Endoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cells | Q36020814 | ||
Trial watch: Chemotherapy with immunogenic cell death inducers | Q36038456 | ||
Targeting of protein ERGIC-53 to the ER/ERGIC/cis-Golgi recycling pathway | Q36236056 | ||
Inhibition of a reductive function of the plasma membrane by bacitracin and antibodies against protein disulfide-isomerase | Q36281651 | ||
Vasostatin, a calreticulin fragment, inhibits angiogenesis and suppresses tumor growth | Q36401336 | ||
Unfolded protein response to autophagy as a promising druggable target for anticancer therapy | Q36403652 | ||
Retention in endoplasmic reticulum 1 (RER1) modulates amyloid-β (Aβ) production by altering trafficking of γ-secretase and amyloid precursor protein (APP). | Q36418911 | ||
Effect of celecoxib on Ca(2+) handling and viability in human prostate cancer cells (PC3). | Q39428795 | ||
Low dose hypericin-PDT induces complete tumor regression in BALB/c mice bearing CT26 colon carcinoma | Q39436362 | ||
ER stress impairs MHC Class I surface expression and increases susceptibility of thyroid cells to NK-mediated cytotoxicity | Q39612923 | ||
Ero1alpha requires oxidizing and normoxic conditions to localize to the mitochondria-associated membrane (MAM). | Q39734860 | ||
Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78. | Q39749582 | ||
GRP-78 secreted by tumor cells blocks the antiangiogenic activity of bortezomib | Q39807121 | ||
Ligation of cancer cell surface GRP78 with antibodies directed against its COOH-terminal domain up-regulates p53 activity and promotes apoptosis | Q39856365 | ||
Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts | Q39919036 | ||
ERP57 membrane translocation dictates the immunogenicity of tumor cell death by controlling the membrane translocation of calreticulin | Q39953260 | ||
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death | Q39984426 | ||
Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulum | Q39994820 | ||
A new tumor-specific variant of GRP78 as target for antibody-based therapy | Q40014019 | ||
Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin. | Q40045975 | ||
The immunosuppressive and protective ability of glucose-regulated protein 78 for improvement of alloimmunity in beta cell transplantation | Q40063531 | ||
Prostate cancer cell proliferation in vitro is modulated by antibodies against glucose-regulated protein 78 isolated from patient serum | Q40200746 | ||
Protein disulfide isomerase expression is related to the invasive properties of malignant glioma | Q40219026 | ||
(-)-Epigallocatechin gallate overcomes resistance to etoposide-induced cell death by targeting the molecular chaperone glucose-regulated protein 78. | Q40230429 | ||
Activation and cross-talk between Akt, NF-kappaB, and unfolded protein response signaling in 1-LN prostate cancer cells consequent to ligation of cell surface-associated GRP78. | Q40303607 | ||
Role of endoplasmic reticulum depletion and multidomain proapoptotic BAX and BAK proteins in shaping cell death after hypericin-mediated photodynamic therapy | Q40321304 | ||
The cotranslational maturation of the type I membrane glycoprotein tyrosinase: the heat shock protein 70 system hands off to the lectin-based chaperone system | Q40409191 | ||
Endoplasmic reticulum stress induction of the Grp78/BiP promoter: activating mechanisms mediated by YY1 and its interactive chromatin modifiers. | Q40421034 | ||
Contrasting functions of calreticulin and calnexin in glycoprotein folding and ER quality control | Q40597954 | ||
Major histocompatibility class one molecule associates with glucose regulated protein (GRP) 78 on the cell surface | Q40789692 | ||
An N-terminal double-arginine motif maintains type II membrane proteins in the endoplasmic reticulum | Q40791455 | ||
Protein-disulfide isomerase (PDI) in FRTL5 cells. pH-dependent thyroglobulin/PDI interactions determine a novel PDI function in the post-endoplasmic reticulum of thyrocytes. | Q40906037 | ||
Humoral immune responses to cathepsin D and glucose-regulated protein 78 in ovarian cancer patients | Q40994712 | ||
Membrane-bound proteindisulfide isomerase (PDI) is involved in regulation of surface expression of thiols and drug sensitivity of B-CLL cells. | Q41102445 | ||
Calcium binding and conformational response in EF-hand proteins | Q41145282 | ||
Retention and retrieval: both mechanisms cooperate to maintain calreticulin in the endoplasmic reticulum. | Q41439078 | ||
A dual role for COOH-terminal lysine residues in pre-Golgi retention and endocytosis of ERGIC-53. | Q41481631 | ||
Heavy chain binding protein (BiP/GRP78) and endoplasmin are exported from the endoplasmic reticulum in rat exocrine pancreatic cells, similar to protein disulfide-isomerase | Q41617941 | ||
Regulation of expression and intracellular distribution of calreticulin, a major calcium binding protein of nonmuscle cells | Q41661789 | ||
A di-acidic (DXE) code directs concentration of cargo during export from the endoplasmic reticulum | Q41666503 | ||
Multiple ways to make disulfides | Q37903530 | ||
The physiological functions of mammalian endoplasmic oxidoreductin 1: on disulfides and more | Q37973411 | ||
Glucose regulated protein 78: a critical link between tumor microenvironment and cancer hallmarks | Q37994524 | ||
The DSL1 complex: the smallest but not the least CATCHR. | Q38001076 | ||
Calreticulin in the immune system: ins and outs | Q38041778 | ||
Rab proteins of the endoplasmic reticulum: functions and interactors | Q38061998 | ||
Crosstalk between ER stress and immunogenic cell death | Q38115887 | ||
Targeting the unfolded protein response in disease. | Q38132652 | ||
The interplay between pathogen-associated and danger-associated molecular patterns: an inflammatory code in cancer? | Q38150096 | ||
Protein disulfide isomerase: a promising target for cancer therapy | Q38159179 | ||
Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential | Q38198491 | ||
Retention mechanisms for ER and Golgi membrane proteins. | Q38209189 | ||
Targeting thapsigargin towards tumors | Q38234334 | ||
GRP78 as a novel predictor of responsiveness to chemotherapy in breast cancer | Q38436413 | ||
A positive signal prevents secretory membrane cargo from recycling between the Golgi and the ER. | Q38971512 | ||
The key role of calreticulin in immunomodulation induced by chemotherapeutic agents | Q38980305 | ||
Detection of tumor-associated antigens in culture supernatants using autoantibodies in sera from patients with bladder cancer | Q39020663 | ||
Overexpression of calreticulin contributes to the development and progression of pancreatic cancer | Q39058690 | ||
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78. | Q39134058 | ||
Whole-cell vaccine coated with recombinant calreticulin enhances activation of dendritic cells and induces tumour-specific immune responses | Q39242176 | ||
Overexpression of GRP94 in breast cancer cells resistant to oxidative stress promotes high levels of cancer cell proliferation and migration: implications for tumor recurrence. | Q39412402 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | endoplasmic reticulum | Q79927 |
molecular chaperones | Q422496 | ||
P304 | page(s) | 291 | |
P577 | publication date | 2014-10-27 | |
P1433 | published in | Frontiers in Oncology | Q26839986 |
P1476 | title | Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognition | |
P478 | volume | 4 |
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