Rectal pre-exposure prophylaxis (PrEP)

scientific article

Rectal pre-exposure prophylaxis (PrEP) is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ANTIVIRAL.2013.09.023
P932PMC publication ID3896093
P698PubMed publication ID24188705
P5875ResearchGate publication ID258280657

P2093author name stringLin Wang
Haitao Yang
Lisa C. Rohan
P2860cites workIs wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activityQ21133918
First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacyQ21135264
Antiretroviral pre-exposure prophylaxis prevents vaginal transmission of HIV-1 in humanized BLT miceQ21144657
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Drug concentrations after topical and oral antiretroviral pre-exposure prophylaxis: implications for HIV prevention in womenQ36839544
Quantitative assessment of altered rectal mucosal permeability due to rectally applied nonoxynol-9, biopsy, and simulated intercourseQ36957266
A modified zinc acetate gel, a potential nonantiretroviral microbicide, is safe and effective against simian-human immunodeficiency virus and herpes simplex virus 2 infection in vivoQ37036620
A social ecology of rectal microbicide acceptability among young men who have sex with men and transgender women in ThailandQ37066942
Lack of prophylactic efficacy of oral maraviroc in macaques despite high drug concentrations in rectal tissuesQ37123335
Preference for gel over suppository as delivery vehicle for a rectal microbicide: results of a randomised, crossover acceptability trial among men who have sex with men.Q37159238
Vaginal and rectal topical microbicide development: safety and efficacy of 1.0% Savvy (C31G) in the pigtailed macaqueQ37862430
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Human lymphohematopoietic reconstitution and immune function in immunodeficient mice receiving cotransplantation of human thymic tissue and CD34(+) cellsQ37981545
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Rectal applications of nonoxynol-9 cause tissue disruption in a monkey modelQ44172316
Rectal douching among Peruvian men who have sex with men, and acceptability of a douche-formulated rectal microbicide to prevent HIV infectionQ45185929
Nonoxynol-9 enhances rectal infection by herpes simplex virus in miceQ45754674
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Safety and toxicity of nonoxynol-9 gel as a rectal microbicide.Q52536992
Quantitative imaging and sigmoidoscopy to assess distribution of rectal microbicide surrogates.Q53481122
High-risk behaviors among men who have sex with men in 6 US cities: baseline data from the EXPLORE StudyQ56897894
Ex vivo culture of human colorectal tissue for the evaluation of candidate microbicidesQ61312701
Sexual behavior and selected health measures: men and women 15-44 years of age, United States, 2002Q64131535
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Cyanovirin-N gel as a topical microbicide prevents rectal transmission of SHIV89.6P in macaquesQ73814670
Hyperosmolar sexual lubricant causes epithelial damage in the distal colon: potential implication for HIV transmissionQ79687951
Colorectal microbicide design: triple combinations of reverse transcriptase inhibitors are optimal against HIV-1 in tissue explantsQ84656743
Acceptability of oral versus rectal HIV preexposure prophylaxis among men who have sex with men and transgender women in PeruQ86167001
Rectal microbicide developmentQ87405838
Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with MenQ24612082
Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalizationQ27318045
Heterosexual risk of HIV-1 infection per sexual act: systematic review and meta-analysis of observational studiesQ28307869
Prevention of SIV rectal transmission and priming of T cell responses in macaques after local pre-exposure application of tenofovir gelQ28473376
Rectal transmission of transmitted/founder HIV-1 is efficiently prevented by topical 1% tenofovir in BLT humanized miceQ28488527
The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeysQ29547689
Anal sex among HIV-seronegative women at high risk of HIV exposure. The HIVNET Vaccine Preparedness Study 2 Protocol TeamQ30233648
Development of a combination microbicide gel formulation containing IQP-0528 and tenofovir for the prevention of HIV infectionQ30411459
An algorithm for the preclinical development of anti-HIV topical microbicidesQ30412043
Acceptability of UC781 gel as a rectal microbicide among HIV-uninfected women and men.Q33833859
Sexual behavior, sexual attraction, and sexual identity in the United States: data from the 2006-2008 National Survey of Family GrowthQ33895589
Animal model for the therapy of acquired immunodeficiency syndrome with reverse transcriptase inhibitorsQ33957283
Identification of personal lubricants that can cause rectal epithelial cell damage and enhance HIV type 1 replication in vitroQ34025707
Isolation of T-cell tropic HTLV-III-like retrovirus from macaquesQ34049156
Heterosexual anal sexuality and anal sex behaviors: a reviewQ34107809
PRO2000 vaginal gel for prevention of HIV-1 infection (Microbicides Development Programme 301): a phase 3, randomised, double-blind, parallel-group trialQ34138687
Genomic Analysis Reveals Pre- and Postchallenge Differences in a Rhesus Macaque AIDS Vaccine Trial: Insights into Mechanisms of Vaccine EfficacyQ34485178
Rectal microbicide development.Q34575590
Preclinical safety and efficacy assessments of dendrimer-based (SPL7013) microbicide gel formulations in a nonhuman primate modelQ34648571
A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007).Q34661892
Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulationsQ34704317
The nonnucleoside reverse transcriptase inhibitor MIV-150 in carrageenan gel prevents rectal transmission of simian/human immunodeficiency virus infection in macaquesQ34982693
A summary of preclinical topical microbicide rectal safety and efficacy evaluations in a pigtailed macaque modelQ34989166
The slippery slope: lubricant use and rectal sexually transmitted infections: a newly identified riskQ35629984
Generation of HIV latency in humanized BLT miceQ35666126
Preclinical evaluation of the HIV-1 fusion inhibitor L'644 as a potential candidate microbicideQ35941336
Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmissionQ36001347
Reformulated tenofovir gel for use as a dual compartment microbicide.Q36159765
Saquinavir inhibits early events associated with establishment of HIV-1 infection: potential role for protease inhibitors in preventionQ36171647
Suppression of viremia and evolution of human immunodeficiency virus type 1 drug resistance in a macaque model for antiretroviral therapyQ36315555
RMP-02/MTN-006: A phase 1 rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of tenofovir 1% gel compared with oral tenofovir disoproxil fumarateQ36359092
A single dose of a MIV-150/Zinc acetate gel provides 24 h of protection against vaginal simian human immunodeficiency virus reverse transcriptase infection, with more limited protection rectally 8-24 h after gel use.Q36359120
Safety and efficacy of tenofovir/IQP-0528 combination gels - a dual compartment microbicide for HIV-1 preventionQ36409617
Compartmentalization of the gut viral reservoir in HIV-1 infected patientsQ36412750
P407language of work or nameEnglishQ1860
P921main subjectpre-exposure prophylaxis against HIVQ7239230
P304page(s)S17-24
P577publication date2013-12-01
P1433published inAntiviral ResearchQ4775352
P1476titleRectal pre-exposure prophylaxis (PrEP)
P478volume100 Suppl