Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities

scientific article

Elucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2012-10-415000
P698PubMed publication ID23426946
P5875ResearchGate publication ID235682528

P50authorJames S O'DonnellQ43228933
Roger PrestonQ58710900
P2093author name stringEimear M Gleeson
Orla Rawley
P2860cites workMutations in the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIIIQ24336195
The Ashwell receptor mitigates the lethal coagulopathy of sepsisQ24596452
Structure of beta-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activityQ27640482
Assembly of asparagine-linked oligosaccharidesQ28131690
Bleeding due to disruption of a cargo-specific ER-to-Golgi transport complexQ28201444
LMAN1 and MCFD2 form a cargo receptor complex and interact with coagulation factor VIII in the early secretory pathwayQ28249792
The cytoprotective protein C pathwayQ28274500
Coagulation factor X interaction with macrophages through its N-glycans protects it from a rapid clearanceQ28484019
Amino acid sequence of human von Willebrand factorQ28630812
Roles of N-linked glycans in the endoplasmic reticulumQ29616458
Glycosylation in cellular mechanisms of health and diseaseQ29617310
Analysis of the site-specific asparagine-linked glycosylation of recombinant human coagulation factor VIIa by glycosidase digestions, liquid chromatography, and mass spectrometryQ32033263
Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpuraQ33339170
Sialyltransferase ST3Gal-IV operates as a dominant modifier of hemostasis by concealing asialoglycoprotein receptor ligandsQ33343091
Differential interaction of coagulation factor VIII and factor V with protein chaperones calnexin and calreticulinQ38337996
A gamma methionine-310 to threonine substitution and consequent N-glycosylation at gamma asparagine-308 identified in a congenital dysfibrinogenemia associated with posttraumatic bleeding, fibrinogen AsahiQ38344795
New carbohydrate site in mutant antithrombin (7 Ile----Asn) with decreased heparin affinityQ38346526
Clotting factor concentrate switching and inhibitor development in hemophilia A.Q39603925
N-linked glycosylation of VWF modulates its interaction with ADAMTS13.Q40059074
Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.Q40117579
In vivo clearance of human protein S in a mouse model: influence of C4b-binding protein and the Heerlen polymorphism.Q40385334
Amino acid distributions around O-linked glycosylation sitesQ41761661
Glycosylation of tissue factor is not essential for its transport or functionsQ41893303
Factor VIII and von Willebrand factor are ligands for the carbohydrate-receptor Siglec-5.Q42133647
A shorter von Willebrand factor survival in O blood group subjects explains how ABO determinants influence plasma von Willebrand factorQ42524319
Specific N-linked glycosylation sites modulate synthesis and secretion of von Willebrand factorQ43086117
Expression of terminal alpha2-6-linked sialic acid on von Willebrand factor specifically enhances proteolysis by ADAMTS13.Q43228846
Congenital disorders of glycosylation type Ia and IIa are associated with different primary haemostatic complications.Q43763482
An influence of ABO blood group on the rate of proteolysis of von Willebrand factor by ADAMTS13.Q44518932
Primary structure of the major O-glycosidically linked carbohydrate unit of human von Willebrand factorQ45196383
Macrophages contribute to the cellular uptake of von Willebrand factor and factor VIII in vivo.Q45261110
Purification of recombinant human tissue factor.Q45937551
Bombay phenotype is associated with reduced plasma-VWF levels and an increased susceptibility to ADAMTS13 proteolysisQ46484313
O-linked glycosylation of von Willebrand factor modulates the interaction with platelet receptor glycoprotein Ib under static and shear stress conditionsQ47879767
Genotype at the Secretor blood group locus is a determinant of plasma von Willebrand factor levelQ60034607
Identification of Galectin-1 and Galectin-3 as Novel Partners for Von Willebrand FactorQ63354161
Two residues in the activation peptide domain contribute to the half-life of factor X in vivoQ63354278
Human factor Va1 and factor Va2: properties in the procoagulant and anticoagulant pathwaysQ73259496
Functional characterization of factor V-Ile359Thr: a novel mutation associated with thrombosisQ75207795
Coagulation abnormalities in the carbohydrate-deficient glycoprotein syndrome: case report and review of the literatureQ77779053
The plasma von Willebrand factor O-glycome comprises a surprising variety of structures including ABH antigens and disialosyl motifsQ84814859
???Q24564873
Carbohydrates and activity of natural and recombinant tissue factorQ33517083
Posttranslational modifications and activity of natural and recombinant tissue factorQ33729216
Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylationQ33784627
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: The CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) ConsortiumQ33817075
Physiological variant of antithrombin-III lacks carbohydrate sidechain at Asn 135.Q34185488
In vivo analysis of the role of O-glycosylations of von Willebrand factor.Q34278082
Identification of O-linked oligosaccharide chains in the activation peptides of blood coagulation factor X. The role of the carbohydrate moieties in the activation of factor X.Q34344830
Mapping the N-glycome of human von Willebrand factorQ34360160
Oligosaccharyltransferase activity is associated with a protein complex composed of ribophorins I and II and a 48 kd proteinQ34369417
Thrombin inhibition by antithrombin III on the subendothelium is explained by the isoform AT betaQ34401769
The oligosaccharide side chain on Asn-135 of alpha-antithrombin, absent in beta-antithrombin, decreases the heparin affinity of the inhibitor by affecting the heparin-induced conformational changeQ34428865
Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells.Q34488999
Carbohydrate moiety of von Willebrand factor is not necessary for maintaining multimeric structure and ristocetin cofactor activity but protects from proteolytic degradationQ34622020
Differences in the fractional abundances of carbohydrates of natural and recombinant human tissue factorQ34625347
Concepts and principles of O-linked glycosylationQ34749639
A role for exposed mannosylations in presentation of human therapeutic self-proteins to CD4+ T lymphocytesQ35829158
Combined deficiency of factor V and factor VIII is due to mutations in either LMAN1 or MCFD2Q35849432
The COPII pathway and hematologic diseaseQ36079805
Asparagine-linked protein glycosylation: from eukaryotic to prokaryotic systemsQ36410806
ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?Q36604393
Structural characterization of site-specific N-glycosylation of recombinant human factor VIII by reversed-phase high-performance liquid chromatography-electrospray ionization mass spectrometryQ36885148
The disappearing act of factor VIII.Q37260659
Functional role of O-linked and N-linked glycosylation sites present on the activation peptide of factor X.Q37363970
Functional roles of the factor VIII B domainQ37497567
Factor VIII and von Willebrand factor--too sweet for their own goodQ37768888
Mechanisms and principles of N-linked protein glycosylationQ37943105
Diseases of glycosylation beyond classical congenital disorders of glycosylationQ37985356
Mammalian sialidases: physiological and pathological roles in cellular functionsQ37989368
Carbohydrate clearance receptors in transfusion medicineQ38030663
Partial glycosylation of antithrombin III asparagine-135 is caused by the serine in the third position of its N-glycosylation consensus sequence and is responsible for production of the beta-antithrombin III isoform with enhanced heparin affinityQ38293560
Glucose trimming and reglucosylation determine glycoprotein association with calnexin in the endoplasmic reticulumQ38295642
A 110-amino acid region within the A1-domain of coagulation factor VIII inhibits secretion from mammalian cellsQ38296274
Partial glycosylation at asparagine-2181 of the second C-type domain of human factor V modulates assembly of the prothrombinase complex.Q38320989
The B domain of coagulation factor VIII interacts with the asialoglycoprotein receptorQ38325193
P433issue19
P407language of work or nameEnglishQ1860
P304page(s)3801-3810
P577publication date2013-02-20
P1433published inBloodQ885070
P1476titleElucidating the role of carbohydrate determinants in regulating hemostasis: insights and opportunities
P478volume121

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cites work (P2860)
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Q97551370Low VWF: insights into pathogenesis, diagnosis, and clinical management
Q45857947Measurement of factor IX activity in plasma-derived and recombinant concentrates: insights from thrombin generation and activation-based assays
Q39299024N-linked glycan truncation causes enhanced clearance of plasma-derived von Willebrand factor.
Q35168028Role of the C-sheet in the maturation of N-glycans on antithrombin: functional relevance of pleiotropic mutations.
Q35824093Thrombin Generating Capacity and Phenotypic Association in ABO Blood Groups
Q43153236Variation of fibrinogen oligosaccharide structure in the acute phase response: Possible haemorrhagic implications

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