Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells

scientific article

Immunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1038/ICB.2012.64
P3181OpenCitations bibliographic resource ID2002200
P932PMC publication ID3540326
P698PubMed publication ID23295415
P5875ResearchGate publication ID234086222

P50authorCatherine VerfaillieQ615166
P2093author name stringStefaan W Van Gool
Sandra A Jacobs
Valerie D Roobrouck
P2860cites workTreatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing mediumQ82092596
Adventitial delivery of an allogeneic bone marrow-derived adherent stem cell in acute myocardial infarction: phase I clinical studyQ82341953
Coinfusion of mesenchymal stromal cells facilitates platelet recovery without increasing leukemia recurrence in haploidentical hematopoietic stem cell transplantation: a randomized, controlled clinical studyQ82808694
Mesenchymal stem cells together with mycophenolate mofetil inhibit antigen presenting cell and T cell infiltration into allogeneic heart graftsQ83074981
Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's diseaseQ83272771
Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant modelQ83978985
Efficacy and safety of ex vivo cultured adult human mesenchymal stem cells (Prochymal™) in pediatric patients with severe refractory acute graft-versus-host disease in a compassionate use studyQ84197372
Development of a surrogate angiogenic potency assay for clinical-grade stem cell productionQ84352859
Efficacy of bone marrow-derived mesenchymal stem cells in the treatment of sclerodermatous chronic graft-versus-host disease: clinical reportQ84931084
Multilineage potential of adult human mesenchymal stem cellsQ27860737
Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statementQ27861120
A perivascular origin for mesenchymal stem cells in multiple human organsQ28131808
Human mesenchymal stem cells modulate allogeneic immune cell responsesQ28288692
Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II studyQ29617267
Human adipose tissue is a source of multipotent stem cellsQ29617385
Pluripotency of mesenchymal stem cells derived from adult marrowQ29617959
Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cellsQ29618766
Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuliQ29618769
Mesenchymal stem cellsQ29619804
Mesenchymal stem cells as trophic mediatorsQ29619806
Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironmentQ29620053
Human mesenchymal stem cells modulate B-cell functionsQ29620705
Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodiesQ30195546
Multipotent adult progenitor cells sustain function of ischemic limbs in mice.Q30480928
Isolation of Oct4-expressing extraembryonic endoderm precursor cell linesQ33507094
Human embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cellsQ33658734
Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+CD25highFOXP3+ regulatory T cells.Q34007524
Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cellsQ34129368
What is a natural killer cell?Q34468687
Mesenchymal stem cell as salvage treatment for refractory chronic GVHDQ34562177
SSEA-4 identifies mesenchymal stem cells from bone marrowQ34576375
Neuroectodermal differentiation from mouse multipotent adult progenitor cellsQ34582250
Regenerative medicine through mesenchymal stem cells for bone and cartilage repair.Q34788797
Identification of genes responsible for osteoblast differentiation from human mesodermal progenitor cellsQ34868815
Treatment of inflammatory diseases with mesenchymal stem cellsQ34987147
Indoleamine 2,3 dioxygenase and regulation of T cell immunityQ36255493
Bone marrow-derived mesenchymal stem cells facilitate engineering of long-lasting functional vasculatureQ36591314
A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarctionQ36634299
Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity.Q36643178
Transplantation of bone marrow-derived stem cells: a promising therapy for stroke.Q36808861
Mesenchymal stem cells in hematopoietic stem cell transplantationQ37396930
Amniotic fluid as a novel source of mesenchymal stem cells for therapeutic transplantationQ73756569
Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodiesQ74505218
Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatcQ74674032
Mesenchymal stem cells inhibit and stimulate mixed lymphocyte cultures and mitogenic responses independently of the major histocompatibility complexQ78833880
Mesenchymal stem cells inhibit the formation of cytotoxic T lymphocytes, but not activated cytotoxic T lymphocytes or natural killer cellsQ79208808
In vivo and in vitro differentiation of myocytes from human bone marrow-derived multipotent progenitor cellsQ79353484
Infusion of allogeneic-related HLA mismatched mesenchymal stem cells for the treatment of incomplete engraftment following autologous haematopoietic stem cell transplantationQ79657081
Pre-clinical safety testing supporting clinical use of allogeneic multipotent adult progenitor cellsQ79791862
Mesenchymal stem cells inhibit generation and function of both CD34+-derived and monocyte-derived dendritic cellsQ80057941
Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cellsQ80413361
The correlation between cotransplantation of mesenchymal stem cells and higher recurrence rate in hematologic malignancy patients: outcome of a pilot clinical studyQ80471824
Application of multipotent mesenchymal stromal cells in pediatric patients following allogeneic stem cell transplantationQ81298136
Human adipose tissue-derived mesenchymal stromal cells as salvage therapy for treatment of severe refractory acute graft-vs.-host disease in two childrenQ81384595
NK cell alloreactivity and allogeneic hematopoietic stem cell transplantationQ81508180
T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppressionQ81704121
HLA-G is a crucial immunosuppressive molecule secreted by adult human mesenchymal stem cellsQ37474210
Stem cells in the treatment of inflammatory arthritisQ37781919
Mesenchymal stem cells for the treatment of multiple sclerosis and other neurological diseasesQ37891375
Cytokine-induced differentiation of multipotent adult progenitor cells into functional smooth muscle cellsQ39076711
Differentiation potential of human postnatal mesenchymal stem cells, mesoangioblasts, and multipotent adult progenitor cells reflected in their transcriptome and partially influenced by the culture conditionsQ39571426
Isolation procedure and characterization of multipotent adult progenitor cells from rat bone marrowQ39723073
Origin of endothelial progenitors in human postnatal bone marrowQ39737487
Interactions between human mesenchymal stem cells and natural killer cellsQ40385365
CD80, CD86 and CD40 provide accessory signals in a multiple-step T-cell activation model.Q41332088
Human bone marrow mesenchymal stromal cells express the neural ganglioside GD2: a novel surface marker for the identification of MSCs.Q41832951
Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repairQ43164474
MAPC culture conditions support the derivation of cells with nascent hypoblast features from bone marrow and blastocystsQ43210499
Human mesenchymal stem cells and immunosuppressive drug interactions in allogeneic responses: an in vitro study using human cellsQ43254669
Suppression of allogeneic T-cell proliferation by human marrow stromal cells: implications in transplantationQ44317237
Infusion of mesenchymal stromal cells can aid hematopoietic recovery following allogeneic hematopoietic stem cell myeloablative transplant: a pilot studyQ44718232
Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantationQ44746492
Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradationQ44786842
Mesenchymal stem cells inhibit the expression of CD25 (interleukin-2 receptor) and CD38 on phytohaemagglutinin-activated lymphocytesQ45024308
Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow.Q45859658
Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease.Q45962719
MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2.Q46034364
Mesenchymal stem cells inhibit lymphocyte proliferation by mitogens and alloantigens by different mechanismsQ46390299
Mesenchymal stem cells induce apoptosis of activated T cellsQ46622786
Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2,3-dioxygenase and prostaglandin E2.Q46939105
Homing of in vitro expanded Stro-1- or Stro-1+ human mesenchymal stem cells into the NOD/SCID mouse and their role in supporting human CD34 cell engraftmentQ47273161
Local delivery of marrow-derived stromal cells augments collateral perfusion through paracrine mechanismsQ47945142
Critical parameters for the isolation of mesenchymal stem cells from umbilical cord blood.Q50790713
Global Characterization and Genomic Stability of Human MultiStem, A Multipotent Adult Progenitor Cell.Q51943608
Bone marrow mesenchymal stem cells inhibit the response of naive and memory antigen-specific T cells to their cognate peptide.Q52008649
Bone marrow-derived mesenchymal stem cells induce both polyclonal expansion and differentiation of B cells isolated from healthy donors and systemic lupus erythematosus patients.Q53515532
Mesenchymal stem cell-natural killer cell interactions: evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NK-cell proliferation.Q53652498
Mesenchymal stem cell-mediated T cell suppression occurs through secreted galectins.Q54396842
Human Multipotent Adult Progenitor Cells Are Nonimmunogenic and Exert Potent Immunomodulatory Effects on Alloreactive T-Cell ResponsesQ56777630
In vitro and in vivo arterial differentiation of human multipotent adult progenitor cellsQ56777865
Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotypeQ56902900
Bone marrow mesenchymal stem cells induce division arrest anergy of activated T cellsQ59102107
Human mesenchymal stem cells inhibit differentiation and function of monocyte-derived dendritic cellsQ61645531
Mesenchymal Stem Cells for Treatment of Therapy-Resistant Graft-versus-Host DiseaseQ63197317
Imprinted X-inactivation in extra-embryonic endoderm cell lines from mouse blastocystsQ64147198
Ex vivo expansion and subsequent infusion of human bone marrow-derived stromal progenitor cells (mesenchymal progenitor cells): implications for therapeutic useQ70803151
Engraftment of allogeneic mesenchymal stem cells in the bone marrow of a patient with severe idiopathic aplastic anemia improves stromaQ73015244
Rapid hematopoietic recovery after coinfusion of autologous-blood stem cells and culture-expanded marrow mesenchymal stem cells in advanced breast cancer patients receiving high-dose chemotherapyQ73358706
Human marrow-derived mesenchymal stem cells (MSCs) express hematopoietic cytokines and support long-term hematopoiesis when differentiated toward stromal and osteogenic lineagesQ73438633
Human periosteum-derived cells maintain phenotypic stability and chondrogenic potential throughout expansion regardless of donor ageQ73521753
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivs 3.0 UnportedQ19125045
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
cellQ7868
mesenchymal stem cellQ1922379
bone marrow cellsQ66004840
hemic and immune systemsQ70202933
P304page(s)32-9
P577publication date2013-01-01
P1433published inImmunology & Cell BiologyQ13731918
P1476titleImmunological characteristics of human mesenchymal stem cells and multipotent adult progenitor cells
P478volume91

Reverse relations

cites work (P2860)
Q43919733A combination of insulin and ubiquitin A20 promotes osteocalcin expression in adipose-derived stem cells
Q43507782A look at the interface between mesenchymal stromal cells and the immune system
Q33671117A novel technique to determine the cell type specific response within an in vitro co-culture model via multi-colour flow cytometry
Q58760232Alginate encapsulated multipotent adult progenitor cells promote corneal stromal cell activation via release of soluble factors
Q89699769Allogeneic umbilical cord-derived mesenchymal stem cell transplantation for treating chronic obstructive pulmonary disease: a pilot clinical study
Q92910500Applicability of adipose-derived mesenchymal stem cells in treatment of patients with type 2 diabetes
Q37565614BPA-toxicity via superoxide anion overload and a deficit in β-catenin signaling in human bone mesenchymal stem cells
Q36326923Biomaterial-mediated strategies targeting vascularization for bone repair
Q34664183Bone marrow mesenchymal stem cells provide an antibiotic-protective niche for persistent viable Mycobacterium tuberculosis that survive antibiotic treatment
Q27321912CD271+ Mesenchymal Stem Cells as a Possible Infectious Niche for Leishmania infantum
Q41191186CRISPR/Cas9-Mediated Knockin Application in Cell Therapy: A Non-viral Procedure for Bystander Treatment of Glioma in Mice.
Q50897287CRISPR/Cas9-based genetic correction for recessive dystrophic epidermolysis bullosa.
Q61818608Cell therapy for ARDS: efficacy of endobronchial versus intravenous administration and biodistribution of MAPCs in a large animal model
Q26822005Comparing the Immunomodulatory Properties of Bone Marrow, Adipose Tissue, and Birth-Associated Tissue Mesenchymal Stromal Cells
Q90208140Comparison of The Therapeutic Effect of Syngeneic, Allogeneic, and Xenogeneic Adipose Tissue-Derived Mesenchymal Stem Cells on Abortion Rates in A Mouse Model
Q57072128Comparison of the biological characteristics of human mesenchymal stem cells derived from exfoliated deciduous teeth, bone marrow, gingival tissue, and umbilical cord
Q64277124Concise Review: Therapeutic Potential of the Mesenchymal Stem Cell Derived Secretome and Extracellular Vesicles for Radiation-Induced Lung Injury: Progress and Hypotheses
Q41141797Crosstalk with Inflammatory Macrophages Shapes the Regulatory Properties of Multipotent Adult Progenitor Cells.
Q89951499Cxcr6-Based Mesenchymal Stem Cell Gene Therapy Potentiates Skin Regeneration in Murine Diabetic Wounds
Q34273076Different culture conditions modulate the immunological properties of adipose stem cells.
Q38981524Emerging role of mesenchymal stem cells during tuberculosis: The fifth element in cell mediated immunity
Q42320604Evaluating Wharton's Jelly-Derived Mesenchymal Stem Cell's Survival, Migration, and Expression of Wound Repair Markers under Conditions of Ischemia-Like Stress
Q26766574Fate decision of mesenchymal stem cells: adipocytes or osteoblasts?
Q55285672Feasibility of mesenchymal stem cell culture expansion for a phase I clinical trial in multiple sclerosis.
Q42214329Fibrin Scaffolds Designing in order to Human Adipose-derived Mesenchymal Stem Cells Differentiation to Chondrocytes in the Presence of TGF-β3
Q36326838Gene editing toward the use of autologous therapies in recessive dystrophic epidermolysis bullosa
Q55411178Generation of hepatocyte- and endocrine pancreatic-like cells from human induced endodermal progenitor cells.
Q38628091Human Mesenchymal Stromal Cell Sheet Enhances Allograft Repair in a Mouse Model
Q96135902Hypoxia-induced shift in the phenotype of proteasome from 26S toward immunoproteasome triggers loss of immunoprivilege of mesenchymal stem cells
Q33872068Immunoregulatory effects of multipotent adult progenitor cells in a porcine ex vivo lung perfusion model
Q100464339Improving the immunosuppressive potential of articular chondroprogenitors in a three-dimensional culture setting
Q51095214Influence of Mesenchymal Stem Cells Conditioned Media on Proliferation of Urinary Tract Cancer Cell Lines and Their Sensitivity to Ciprofloxacin.
Q47868876Inhibition of neuropathic hyperalgesia by intrathecal bone marrow stromal cells is associated with alteration of multiple soluble factors in cerebrospinal fluid.
Q50472681Involvement of primary mesenchymal precursors and hematopoietic bone marrow cells from chronic myeloid leukemia patients by BCR-ABL1 fusion gene.
Q43242462Long-term therapeutic effects of mesenchymal stem cells compared to dexamethasone on recurrent experimental autoimmune uveitis of rats
Q64985918Mechanisms of unprimed and dexamethasone-primed nonviral gene delivery to human mesenchymal stem cells.
Q59327153Mesenchymal Stem Cell Therapy for Aging Frailty
Q90310612Mesenchymal Stem Cells Extract (MSCsE)-Based Therapy Alleviates Xerostomia and Keratoconjunctivitis Sicca in Sjogren's Syndrome-Like Disease
Q92650424Mesenchymal Stromal Cell Therapeutic Delivery: Translational Challenges to Clinical Application
Q92622923Mesenchymal Stromal Cells Modulate Corneal Alloimmunity via Secretion of Hepatocyte Growth Factor
Q58855503Mesenchymal Stromal Cells: From Discovery to Manufacturing and Commercialization
Q50075766Mesenchymal Stromal/Stem Cells: A New Era in the Cell-Based Targeted Gene Therapy of Cancer.
Q85945994Mesenchymal stem cells alleviate atherosclerosis by elevating number and function of CD4(+)CD25 (+)FOXP3 (+) regulatory T-cells and inhibiting macrophage foam cell formation
Q38110707Mesenchymal stem cells for the treatment and prevention of graft-versus-host disease: experiments and practice.
Q38207602Mesenchymal stem cells in treating autism: Novel insights
Q24305096Mesenchymal stem cells suppress T cells by inducing apoptosis and through PD-1/B7-H1 interactions
Q38725481Mesenchymal stromal cells in renal transplantation: opportunities and challenges.
Q47589580Molecular effect of human umbilical cord blood CD34-positive and CD34-negative stem cells and their conjugate in azoospermic mice
Q40173940Monitoring the ex-vivo expansion of human mesenchymal stem/stromal cells in xeno-free microcarrier-based reactor systems by MIR spectroscopy
Q38928462Multipotent adult progenitor cells for hypoxic-ischemic injury in the preterm brain.
Q40214885Multipotent adult progenitor cells improve the hematopoietic function in myelodysplasia.
Q42406826Multipotent adult progenitor cells on an allograft scaffold facilitate the bone repair process
Q36070752Neuroinflammatory signals enhance the immunomodulatory and neuroprotective properties of multipotent adult progenitor cells
Q27316366Neuroprotective Potential of Mesenchymal Stem Cell-Based Therapy in Acute Stages of TNBS-Induced Colitis in Guinea-Pigs
Q36870064Olfactory ecto-mesenchymal stem cells possess immunoregulatory function and suppress autoimmune arthritis
Q41446638Osteogenic Potential of Multipotent Adult Progenitor Cells for Calvaria Bone Regeneration
Q39174525Osteogenic potential of stem cells-seeded bioactive nanocomposite scaffolds: A comparative study between human mesenchymal stem cells derived from bone, umbilical cord Wharton's jelly, and adipose tissue
Q37500590Partial Cranial Cruciate Ligament Tears Treated with Stem Cell and Platelet-Rich Plasma Combination Therapy in 36 Dogs: A Retrospective Study
Q39262680Perinatal Brain Injury As a Consequence of Preterm Birth and Intrauterine Inflammation: Designing Targeted Stem Cell Therapies.
Q38977281Pharmaceuticals and Stem Cells in Autism Spectrum Disorders: Wishful Thinking?
Q35806824Physical Activity Increases the Total Number of Bone-Marrow-Derived Mesenchymal Stem Cells, Enhances Their Osteogenic Potential, and Inhibits Their Adipogenic Properties
Q89105506Roles of Mesenchymal Stem Cells in Tissue Regeneration and Immunomodulation
Q38816893Secretome profiling of cytokines and growth factors reveals that neuro-glial differentiation is associated with the down-regulation of Chemokine Ligand 2 (MCP-1/CCL2) in amniotic fluid derived-mesenchymal progenitor cells.
Q40400293Solution-Phase Crosstalk and Regulatory Interactions Between Multipotent Adult Progenitor Cells and Peripheral Blood Mononuclear Cells
Q27025609Stem Cells for Cutaneous Wound Healing
Q46681657Stem Cells in Spinal Fusion
Q38601272Stem cell therapy for cardiac regeneration: hits and misses.
Q58698694Stem cell therapy in autism: recent insights
Q40122051Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas
Q48107914Stem cells and cell-based therapies for cerebral palsy: A call for rigor
Q55313740The Effect of Antidepressants on Mesenchymal Stem Cell Differentiation.
Q64260095The Potential of Stem Cell Therapy to Repair White Matter Injury in Preterm Infants: Lessons Learned From Experimental Models
Q92528775The Role of Mesenchymal Stem Cells in Radiation-Induced Lung Fibrosis
Q26781292The immune response of stem cells in subretinal transplantation
Q42621315The issue of immunology in stem cell therapies: a pharmaceutical perspective
Q33577019The neuroprotective effects of human bone marrow mesenchymal stem cells are dose-dependent in TNBS colitis
Q28077974Therapeutic Strategies for Oxidative Stress-Related Cardiovascular Diseases: Removal of Excess Reactive Oxygen Species in Adult Stem Cells
Q60912266Transplantation of bone marrow mesenchymal stromal cells attenuates liver fibrosis in mice by regulating macrophage subtypes
Q36269896Uncovering stem cell differentiation factors for salivary gland regeneration by quantitative analysis of differential proteomes
Q50064941Unravelling the biological secrets of microchimerism by single-cell analysis

Search more.