DNA Aptamers in the Diagnosis and Treatment of Human Diseases

scientific article

DNA Aptamers in the Diagnosis and Treatment of Human Diseases is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.3390/MOLECULES201219739
P932PMC publication ID6332121
P698PubMed publication ID26610462
P5875ResearchGate publication ID284748852

P2093author name stringGe Liu
Qinchang Zhu
Masaaki Kai
P2860cites workInhibition of HIV-1 protease expression in T cells owing to DNA aptamer-mediated specific delivery of siRNA.Q44432574
Enzyme-linked small-molecule detection using split aptamer ligationQ48153423
Development of a fluorescent enzyme-linked DNA aptamer-magnetic bead sandwich assay and portable fluorometer for sensitive and rapid leishmania detection in sandflies.Q50483529
Screening of DNA aptamers against myoglobin using a positive and negative selection units integrated microfluidic chip and its biosensing application.Q51075610
Aptamers as therapeutics.Q51813594
In vitro selection of DNA aptamers to anthrax spores with electrochemiluminescence detectionQ56902246
Affinity analysis of DNA aptamer-peptide interactions using gold nanoparticlesQ83169956
Sensitive point-of-care monitoring of cardiac biomarker myoglobin using aptamer and ubiquitous personal glucose meterQ85301777
Cell-SELEX based selection and characterization of DNA aptamer recognizing human hepatocarcinomaQ86101126
Structural basis for discriminatory recognition of Plasmodium lactate dehydrogenase by a DNA aptamerQ27679972
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymeraseQ27860794
In vitro selection of RNA molecules that bind specific ligandsQ27861109
Selection of DNA aptamers against glioblastoma cells with high affinity and specificityQ28484184
Development of a novel DNA aptamer ligand targeting to primary cultured tumor endothelial cells by a cell-based SELEX methodQ28485460
Single-Stranded DNA Aptamers against Pathogens and Toxins: Identification and Biosensing ApplicationsQ30406535
DNA Aptamer Technology for Personalized MedicineQ30412965
DNA-aptamer targeting vimentin for tumor therapy in vivo.Q30415521
Aptamer in bioanalytical applications.Q30466572
Design strategies for aptamer-based biosensorsQ30469779
Aptamers and their biological applicationsQ30470240
Chemically modified nucleic acid aptamers for in vitro selections: evolving evolutionQ30903585
Influence of the 2'-hydroxyl group conformation on the stability of A-form helices in RNA.Q31027558
Effect of 3'-end capping of aptamer with various 2',4'-bridged nucleotides: Enzymatic post-modification toward a practical use of polyclonal aptamersQ38346492
ARC-1779, a PEGylated aptamer antagonist of von Willebrand factor for potential use as an anticoagulant or antithrombotic agentQ38353688
Structure-Switching Signaling AptamersQ38355518
Molecular assembly of an aptamer-drug conjugate for targeted drug delivery to tumor cellsQ38356248
Array-based evolution of DNA aptamers allows modelling of an explicit sequence-fitness landscapeQ38358691
Aptamer nanomedicine for cancer therapeutics: barriers and potential for translation.Q38366753
Outlook for aptamers after twenty five yearsQ38440811
A Highlight of Recent Advances in Aptamer Technology and Its ApplicationQ38541697
DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics.Q38989650
A Cell-based Single-stranded DNA Aptamer Specifically Targets Gastric CancerQ39025264
Epirubicin loaded super paramagnetic iron oxide nanoparticle-aptamer bioconjugate for combined colon cancer therapy and imaging in vivoQ39128974
Anticancer role of MUC1 aptamer-miR-29b chimera in epithelial ovarian carcinoma cells through regulation of PTEN methylationQ39239168
Simple PEG modification of DNA aptamer based on copper ion coordination for tumor targetingQ39682746
Synthesis and properties of mirror-image DNAQ40422935
A DNA aptamer prevents influenza infection by blocking the receptor binding region of the viral hemagglutininQ31111010
Novel combinatorial selection of phosphorothioate oligonucleotide aptamersQ31960296
DNA aptamers against the MUC1 tumour marker: design of aptamer-antibody sandwich ELISA for the early diagnosis of epithelial tumoursQ33293976
Selection of DNA aptamers against VEGF165 using a protein competitor and the aptamer blotting methodQ33313271
A dose ranging phase I/II trial of the von Willebrand factor inhibiting aptamer ARC1779 in patients with congenital thrombotic thrombocytopenic purpuraQ33396658
DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cellsQ33591381
DNA aptamer evolved by cell-SELEX for recognition of prostate cancerQ33793416
Cell-type-specific, Aptamer-functionalized Agents for Targeted Disease TherapyQ33834772
In vitro selection of functional nucleic acidsQ33953593
Probing high affinity sequences of DNA aptamer against VEGF165Q34168165
Remyelination induced by a DNA aptamer in a mouse model of multiple sclerosis.Q34326301
Locked nucleic acids: a promising molecular family for gene-function analysis and antisense drug developmentQ34332193
Rapid one-step selection method for generating nucleic acid aptamers: development of a DNA aptamer against α-bungarotoxinQ34364189
Pegaptanib (Macugen): treating neovascular age-related macular degeneration and current role in clinical practice.Q34560799
A DNA aptamer with high affinity and specificity for molecular recognition and targeting therapy of gastric cancerQ34565529
Selection of single-stranded DNA molecules that bind and inhibit human thrombinQ34616171
Selection and characterization of DNA aptamers for use in detection of avian influenza virus H5N1.Q34633259
Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growthQ34695253
A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemiaQ34723932
Development of an efficient targeted cell-SELEX procedure for DNA aptamer reagentsQ34964507
DNA aptamers that target human glioblastoma multiforme cells overexpressing epidermal growth factor receptor variant III in vitro.Q35059032
In vitro selection of DNA aptamers for metastatic breast cancer cell recognition and tissue imaging.Q35180688
Thrombin, inflammation, and cardiovascular disease: an epidemiologic perspectiveQ35217275
Selection of LNA-containing DNA aptamers against recombinant human CD73.Q35568409
Aptamers overview: selection, features and applicationsQ35599983
A controllable aptamer-based self-assembled DNA dendrimer for high affinity targeting, bioimaging and drug deliveryQ35605916
Molecular Recognition of Human Liver Cancer Cells Using DNA Aptamers Generated via Cell-SELEX.Q35621766
Single-Round Patterned DNA Library Microarray Aptamer Lead IdentificationQ35657036
DNA Aptamer Selected against Pancreatic Ductal Adenocarcinoma for in vivo Imaging and Clinical Tissue RecognitionQ35686260
Cell-SELEX based selection and optimization of DNA aptamers for specific recognition of human cholangiocarcinoma QBC-939 cells.Q35693567
Applications of aptasensors in clinical diagnosticsQ35831331
A phase II trial of AS1411 (a novel nucleolin-targeted DNA aptamer) in metastatic renal cell carcinomaQ36028980
Building oligonucleotide therapeutics using non-natural chemistriesQ36627400
The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridineQ36675591
Dimeric DNA Aptamer Complexes for High-capacity-targeted Drug Delivery Using pH-sensitive Covalent LinkagesQ37065549
Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo.Q37240103
Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysisQ37319748
RNA conformational classesQ37519987
Emerging pharmacologic therapies for wet age-related macular degenerationQ37558041
Application of locked nucleic acids to improve aptamer in vivo stability and targeting functionQ37619467
AS-1411, a guanosine-rich oligonucleotide aptamer targeting nucleolin for the potential treatment of cancer, including acute myeloid leukemia.Q37689055
Automated modular synthesis of aptamer-drug conjugates for targeted drug delivery.Q37700995
Aptamer-based molecular recognition for biosensor development.Q37774275
Molecular evolution of functional nucleic acids with chemical modificationsQ37780443
Improving the stability of aptamers by chemical modificationQ37916666
Aptamer-conjugated nanomaterials and their applicationsQ37948000
Single-stranded DNA (ssDNA) production in DNA aptamer generationQ37982285
Smart ligand: aptamer-mediated targeted delivery of chemotherapeutic drugs and siRNA for cancer therapyQ38115387
Aptamer-based biosensors for biomedical diagnosticsQ38204726
Aptamer binding assays for proteins: the thrombin example--a review.Q38226959
Oligonucleotide aptamers: new tools for targeted cancer therapyQ38237132
In vitro Selection of DNA Aptamers to Glioblastoma Multiforme.Q38274697
Application of a novel in vitro selection technique to isolate and characterise high affinity DNA aptamers binding mammalian prion proteinsQ38291515
The nucleolin targeting aptamer AS1411 destabilizes Bcl-2 messenger RNA in human breast cancer cellsQ38292167
Post-SELEX chemical optimization of a trypanosome-specific RNA aptamerQ38294223
Evolution of DNA aptamers through in vitro metastatic-cell-based systematic evolution of ligands by exponential enrichment for metastatic cancer recognition and imagingQ38299818
RNA aptamers as genetic control devices: the potential of riboswitches as synthetic elements for regulating gene expressionQ38301085
An AS1411 aptamer-conjugated liposomal system containing a bubble-generating agent for tumor-specific chemotherapy that overcomes multidrug resistance.Q38301354
Magnetic-assisted rapid aptamer selection (MARAS) for generating high-affinity DNA aptamer using rotating magnetic fieldsQ38307210
Target-induced conjunction of split aptamer fragments and assembly with a water-soluble conjugated polymer for improved protein detection.Q38309039
A two-step stimulus-response cell-SELEX method to generate a DNA aptamer to recognize inflamed human aortic endothelial cells as a potential in vivo molecular probe for atherosclerosis plaque detection.Q38314236
In silico maturation of binding-specificity of DNA aptamers against Proteus mirabilisQ38316483
Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell captureQ38317170
Label-free detection of prion protein with its DNA aptamer through the formation of T-Hg2+-T configurationQ38323293
Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structuresQ38330348
Aptamer-functionalized PEG-PLGA nanoparticles for enhanced anti-glioma drug deliveryQ38333122
The von Willebrand inhibitor ARC1779 reduces cerebral embolization after carotid endarterectomy: a randomized trialQ38334013
Structure-switching signaling aptamers: transducing molecular recognition into fluorescence signalingQ38342545
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectnucleotide aptamersQ49849144
neoplasmQ1216998
drug delivery systemQ64829245
P304page(s)20979-20997
P577publication date2015-11-25
P1433published inMoleculesQ151332
P1476titleDNA Aptamers in the Diagnosis and Treatment of Human Diseases
P478volume20

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cites work (P2860)
Q92703795Biomedical Application of Electroactive Polymers in Electrochemical Sensors: A Review
Q60949418DNA Aptamers for the Functionalisation of DNA Origami Nanostructures
Q52669903Design of Modular G-quadruplex Ligands.
Q39385781Materials and microfluidics: enabling the efficient isolation and analysis of circulating tumour cells
Q99544596Paper-based fluorogenic RNA aptamer sensors for label-free detection of small molecules
Q89968185Post-SELEX Optimization and Characterization of a Prostate Cancer Cell-Specific Aptamer for Diagnosis
Q92152187Targeting microRNAs as a Therapeutic Strategy to Reduce Oxidative Stress in Diabetes

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