Unity in diversity: shared mechanism of entry among paramyxoviruses

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Unity in diversity: shared mechanism of entry among paramyxoviruses is …
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P356DOI10.1016/BS.PMBTS.2014.10.001
P8608Fatcat IDrelease_ata6dhl55jajjabx4xcvteiicq
P3181OpenCitations bibliographic resource ID1678668
P932PMC publication ID4369139
P698PubMed publication ID25595799

P50authorJean-Louis PalgenQ63707736
Matteo PorottoQ101403329
Anne MosconaQ113032251
P2093author name stringLaura M Palermo
Eric M Jurgens
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A mature and fusogenic form of the Nipah virus fusion protein requires proteolytic processing by cathepsin L.Q45420084
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The nipah virus fusion protein is cleaved within the endosomal compartmentQ45447131
Anti-G protein antibody responses to respiratory syncytial virus infection or vaccination are associated with inhibition of G protein CX3C-CX3CR1 binding and leukocyte chemotaxisQ45553949
Neuraminidase treatment of respiratory syncytial virus-infected cells or virions, but not target cells, enhances cell-cell fusion and infectionQ45722004
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The second receptor binding site of the globular head of the Newcastle disease virus hemagglutinin-neuraminidase activates the stalk of multiple paramyxovirus receptor binding proteins to trigger fusionQ39375677
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Strength of envelope protein interaction modulates cytopathicity of measles virusQ39683453
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Relative affinity of the human parainfluenza virus type 3 hemagglutinin-neuraminidase for sialic acid correlates with virus-induced fusion activity.Q40047823
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The heads of the measles virus attachment protein move to transmit the fusion-triggering signalQ41836179
Respiratory syncytial virus G protein CX3C motif impairs human airway epithelial and immune cell responsesQ41838015
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Entry of Newcastle Disease Virus into the host cell: role of acidic pH and endocytosisQ41924449
Cathepsin L is involved in proteolytic processing of the Hendra virus fusion proteinQ42042006
Low-pH-induced membrane fusion mediated by human metapneumovirus F protein is a rare, strain-dependent phenomenonQ42148034
Human metapneumovirus infection in children hospitalized for wheezingQ42412739
Genetic analysis of J-virus and Beilong virus using minirepliconsQ43791199
Trimeric transmembrane domain interactions in paramyxovirus fusion proteins: roles in protein folding, stability, and functionQ37388782
Amino acid substitutions in the F-specific domain in the stalk of the newcastle disease virus HN protein modulate fusion and interfere with its interaction with the F proteinQ37596488
Biological significance of the second receptor binding site of Newcastle disease virus hemagglutinin-neuraminidase proteinQ37596521
Fusion activation through attachment protein stalk domains indicates a conserved core mechanism of paramyxovirus entry into cellsQ37713834
Roles of the putative integrin-binding motif of the human metapneumovirus fusion (f) protein in cell-cell fusion, viral infectivity, and pathogenesisQ37713859
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Heparin-like structures on respiratory syncytial virus are involved in its infectivity in vitro.Q38334591
Structure of the measles virus hemagglutinin bound to its cellular receptor SLAMQ27666483
Structure of Respiratory Syncytial Virus Fusion Glycoprotein in the Postfusion Conformation Reveals Preservation of Neutralizing EpitopesQ27668015
Structure of the Newcastle disease virus hemagglutinin-neuraminidase (HN) ectodomain reveals a four-helix bundle stalkQ27672276
Structure of the cleavage-activated prefusion form of the parainfluenza virus 5 fusion proteinQ27673665
Structure and Mutagenesis of the Parainfluenza Virus 5 Hemagglutinin-Neuraminidase Stalk Domain Reveals a Four-Helix Bundle and the Role of the Stalk in Fusion PromotionQ27674994
Structure of the parainfluenza virus 5 (PIV5) hemagglutinin-neuraminidase (HN) ectodomainQ27679696
Interaction between the Hemagglutinin-Neuraminidase and Fusion Glycoproteins of Human Parainfluenza Virus Type III Regulates Viral Growth In VivoQ27680424
SLAM (CDw150) is a cellular receptor for measles virusQ28145297
Identification of nucleolin as a cellular receptor for human respiratory syncytial virusQ28245563
Membrane fusion machines of paramyxoviruses: capture of intermediates of fusionQ28345073
A general strategy to endow natural fusion-protein-derived peptides with potent antiviral activityQ28729918
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysisQ29619821
Role of sequence and structure of the Hendra fusion protein fusion peptide in membrane fusionQ30417577
Transmembrane orientation and possible role of the fusogenic peptide from parainfluenza virus 5 (PIV5) in promoting fusionQ30498517
Fatal measles virus infection prevented by brain-penetrant fusion inhibitorsQ30557599
Complete genome sequence of Fer-de-Lance virus reveals a novel gene in reptilian paramyxovirusesQ30891208
CD150 (SLAM) is a receptor for measles virus but is not involved in viral contact-mediated proliferation inhibitionQ30987804
Small interfering RNA profiling reveals key role of clathrin-mediated endocytosis and early endosome formation for infection by respiratory syncytial virusQ33284309
Entry and fusion of emerging paramyxovirusesQ33619233
Respiratory syncytial virus (RSV) SH and G proteins are not essential for viral replication in vitro: clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutantQ33738521
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Influence of the human parainfluenza virus 3 attachment protein's neuraminidase activity on its capacity to activate the fusion proteinQ33782736
Membrane fusion promoted by increasing surface densities of the paramyxovirus F and HN proteins: comparison of fusion reactions mediated by simian virus 5 F, human parainfluenza virus type 3 F, and influenza virus HA.Q33784602
A single amino acid change in the Newcastle disease virus fusion protein alters the requirement for HN protein in fusionQ33787073
Structure of the uncleaved ectodomain of the paramyxovirus (hPIV3) fusion proteinQ33855371
The measles virus hemagglutinin stalk: structures and functions of the central fusion activation and membrane-proximal segmentsQ33887869
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusionQ33934074
Infection of nonhuman primates with recombinant human metapneumovirus lacking the SH, G, or M2-2 protein categorizes each as a nonessential accessory protein and identifies vaccine candidatesQ33984333
Tumor cell marker PVRL4 (nectin 4) is an epithelial cell receptor for measles virusQ34013640
The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replicationQ34069934
Novel paramyxoviruses in free-ranging European bats.Q34318362
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Mutations in the cytoplasmic domain of a paramyxovirus fusion glycoprotein rescue syncytium formation and eliminate the hemagglutinin-neuraminidase protein requirement for membrane fusionQ34462207
Triggering of human parainfluenza virus 3 fusion protein (F) by the hemagglutinin-neuraminidase (HN) protein: an HN mutation diminishes the rate of F activation and fusionQ34745220
Role of cellular glycosaminoglycans and charged regions of viral G protein in human metapneumovirus infectionQ34825946
Triggering of the newcastle disease virus fusion protein by a chimeric attachment protein that binds to Nipah virus receptorsQ34978997
Mutation at residue 523 creates a second receptor binding site on human parainfluenza virus type 1 hemagglutinin-neuraminidase proteinQ35024321
Unraveling a three-step spatiotemporal mechanism of triggering of receptor-induced Nipah virus fusion and cell entry.Q35053036
Nipah virus uses leukocytes for efficient dissemination within a hostQ35140337
Premature activation of the paramyxovirus fusion protein before target cell attachment with corruption of the viral fusion machineryQ35515383
Capture and imaging of a prehairpin fusion intermediate of the paramyxovirus PIV5Q35641392
Mechanism of fusion triggering by human parainfluenza virus type III: communication between viral glycoproteins during entryQ35643883
Receptor-binding specificity of the human parainfluenza virus type 1 hemagglutinin-neuraminidase glycoproteinQ35664943
A second receptor binding site on human parainfluenza virus type 3 hemagglutinin-neuraminidase contributes to activation of the fusion mechanismQ35785169
The paramyxovirus fusion protein C-terminal region: mutagenesis indicates an indivisible protein unitQ35826179
Beyond anchoring: the expanding role of the hendra virus fusion protein transmembrane domain in protein folding, stability, and function.Q35826196
Human metapneumovirus (HMPV) binding and infection are mediated by interactions between the HMPV fusion protein and heparan sulfateQ35826221
Paramyxovirus fusion and entry: multiple paths to a common endQ35943669
Structural rearrangements of the central region of the morbillivirus attachment protein stalk domain trigger F protein refolding for membrane fusionQ35956606
Adaptation of human parainfluenza virus to airway epithelium reveals fusion properties required for growth in host tissueQ36029211
Mutations in the stalk of the measles virus hemagglutinin protein decrease fusion but do not interfere with virus-specific interaction with the homologous fusion proteinQ36098830
Fusion activation by a headless parainfluenza virus 5 hemagglutinin-neuraminidase stalk suggests a modular mechanism for triggeringQ36300779
Reversible inhibition of fusion activity of a paramyxovirus fusion protein by an engineered disulfide bond in the membrane-proximal external regionQ36363793
N-Glycans on the Nipah virus attachment glycoprotein modulate fusion and viral entry as they protect against antibody neutralizationQ36363882
Membrane fusion triggering: three modules with different structure and function in the upper half of the measles virus attachment protein stalkQ36385788
Triggering the measles virus membrane fusion machineryQ36397970
Mechanism for active membrane fusion triggering by morbillivirus attachment proteinQ36506813
Complementation between avirulent Newcastle disease virus and a fusion protein gene expressed from a retrovirus vector: requirements for membrane fusionQ36680205
Fusion properties of cells persistently infected with human parainfluenza virus type 3: participation of hemagglutinin-neuraminidase in membrane fusionQ36692466
Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shedQ36726124
Engineered intermonomeric disulfide bonds in the globular domain of Newcastle disease virus hemagglutinin-neuraminidase protein: implications for the mechanism of fusion promotionQ36949597
Residues in the stalk domain of the hendra virus g glycoprotein modulate conformational changes associated with receptor bindingQ36949836
Envelope protein dynamics in paramyxovirus entryQ36994390
Paramyxoviruses: different receptors - different mechanisms of fusionQ37019201
Low-pH triggering of human metapneumovirus fusion: essential residues and importance in entryQ37051640
Human parainfluenza virus infection of the airway epithelium: viral hemagglutinin-neuraminidase regulates fusion protein activation and modulates infectivity.Q37232820
Identification of a region in the stalk domain of the nipah virus receptor binding protein that is critical for fusion activationQ37252586
Mutations in the parainfluenza virus 5 fusion protein reveal domains important for fusion triggering and metastabilityQ37336715
P407language of work or nameEnglishQ1860
P921main subjectvirologyQ7215
P304page(s)1-32
P577publication date2015-01-01
P1433published inProgress in Molecular Biology and Translational ScienceQ15753415
P1476titleUnity in diversity: shared mechanism of entry among paramyxoviruses
P478volume129