Nanoparticle-based targeted therapeutics in head-and-neck cancer

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Nanoparticle-based targeted therapeutics in head-and-neck cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7150/IJMS.10083
P932PMC publication ID4293184
P698PubMed publication ID25589895
P5875ResearchGate publication ID270964360

P2093author name stringTing-Ting Wu
Shui-Hong Zhou
P2860cites workUbiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteinsQ24293182
A novel member of the Rhomboid family, RHBDD1, regulates BIK-mediated apoptosisQ24309275
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cellsQ24318727
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphomaQ24322614
Phosphorylation and cleavage of presenilin-associated rhomboid-like protein (PARL) promotes changes in mitochondrial morphologyQ24675079
The prognostic value of the hypoxia markers CA IX and GLUT 1 and the cytokines VEGF and IL 6 in head and neck squamous cell carcinoma treated by radiotherapy +/- chemotherapyQ24801373
Improving conventional enhanced permeability and retention (EPR) effects; what is the appropriate target?Q26999332
Crystal structure of the human glucose transporter GLUT1Q27690274
Levels of TGF-α and EGFR Protein in Head and Neck Squamous Cell Carcinoma and Patient SurvivalQ27851502
Global cancer statistics, 2002Q27860562
Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008Q27860674
Cancer statistics, 2013Q27860762
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
On the Origin of Cancer CellsQ27861025
Post-transcriptional gene silencing by double-stranded RNAQ28205087
Radiotherapy enhancement with gold nanoparticlesQ28288052
Smoking and drinking in relation to oral and pharyngeal cancerQ28297089
Case-control study of human papillomavirus and oropharyngeal cancerQ28301695
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervalsQ29547713
An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cellsQ29547714
Nanocarriers as an emerging platform for cancer therapyQ29616699
Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neckQ29619277
Current advances in research and clinical applications of PLGA-based nanotechnologyQ30482916
Targeted killing of cancer cells in vivo and in vitro with EGF-directed carbon nanotube-based drug delivery.Q30486828
Poly-L-arginine and Dextran Sulfate-Based Nanocomplex for Epidermal Growth Factor Receptor (EGFR) siRNA Delivery: Its Application for Head and Neck Cancer TreatmentQ31043482
Selective laser photo-thermal therapy of epithelial carcinoma using anti-EGFR antibody conjugated gold nanoparticlesQ33224381
Photodynamic therapy with the phthalocyanine photosensitizer Pc 4: the case experience with preclinical mechanistic and early clinical-translational studiesQ33280687
Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survivalQ33515519
Heat shock protein 27 as a new therapeutic target for radiation sensitization of head and neck squamous cell carcinomaQ33713871
CK2 modulation of NF-kappaB, TP53, and the malignant phenotype in head and neck cancer by anti-CK2 oligonucleotides in vitro or in vivo via sub-50-nm nanocapsules.Q33817704
Metabolic markers in relation to hypoxia; staining patterns and colocalization of pimonidazole, HIF-1α, CAIX, LDH-5, GLUT-1, MCT1 and MCT4Q33898862
Effectiveness of combined modality radiotherapy of orthotopic human squamous cell carcinomas in Nu/Nu mice using cetuximab, tirapazamine and MnSOD-plasmid liposome gene therapyQ33972586
Effective Drug Delivery, In Vitro and In Vivo, by Carbon-Based Nanovectors Noncovalently Loaded with Unmodified PaclitaxelQ34111578
Pegnology: a review of PEG-ylated systemsQ34113495
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACEQ34247194
Determination of the role of the human RNase H1 in the pharmacology of DNA-like antisense drugsQ34298362
Local intraluminal infusion of biodegradable polymeric nanoparticles. A novel approach for prolonged drug delivery after balloon angioplastyQ38561887
Polymersome-mediated delivery of combination anticancer therapy to head and neck cancer cells: 2D and 3D in vitro evaluationQ39023305
Lentiviral Vector Mediated Delivery of RHBDD1 shRNA down Regulated the Proliferation of Human Glioblastoma CellsQ39120825
RRM2 Regulates Bcl-2 in Head and Neck and Lung Cancers: A Potential Target for Cancer TherapyQ39146064
Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma.Q39218915
Nanobody-albumin nanoparticles (NANAPs) for the delivery of a multikinase inhibitor 17864 to EGFR overexpressing tumor cellsQ39243572
Folate-targeted polymeric nanoparticle formulation of docetaxel is an effective molecularly targeted radiosensitizer with efficacy dependent on the timing of radiotherapyQ39325848
Synthesis and characterization of amphiphilic chitosan derivatives as a nano-carrier for paclitaxel deliveryQ39423186
Gold nanorod-sphingosine kinase siRNA nanocomplexes: a novel therapeutic tool for potent radiosensitization of head and neck cancerQ39429999
Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA.Q39470280
Cationic liposomal co-delivery of small interfering RNA and a MEK inhibitor for enhanced anticancer efficacyQ39481822
Transferrin receptors in human tissues: their distribution and possible clinical relevanceQ39510082
Oligodeoxynucleotides as inhibitors of gene expression: a review.Q39636846
Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drugQ39640656
Antisense treatment of IGF-IR enhances chemosensitivity in squamous cell carcinomas of the head and neckQ39706443
Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathwayQ39749612
Inhibition of the EGFR with nanoparticles encapsulating antisense oligonucleotides of the EGFR enhances radiosensitivity in SCCVII cellsQ39817106
Inhibition of cell proliferation and glucose uptake in human laryngeal carcinoma cells by antisense oligonucleotides against glucose transporter-1.Q39851737
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesisQ39872802
Inducible NO synthase confers chemoresistance in head and neck cancer by modulating survivinQ39897646
Construction and identification of an antisense glucose transporter-1 plasmidQ39933194
Down-regulation of Mcl-1 with antisense technology alters the effect of various cytotoxic agents used in treatment of squamous cell carcinoma of the head and neck.Q39979580
Antitumor mechanisms of systemically administered epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neckQ40048557
Protective role of Hsp27 protein against gamma radiation-induced apoptosis and radiosensitization effects of Hsp27 gene silencing in different human tumor cellsQ40057512
Tumor targeting with antibody-functionalized, radiolabeled carbon nanotubesQ40112405
Effects of MnSOD-plasmid liposome gene therapy on antioxidant levels in irradiated murine oral cavity orthotopic tumorsQ40168136
Effect of EGFR antagonists gefitinib (Iressa) and C225 (Cetuximab) on MnSOD-plasmid liposome transgene radiosensitization of a murine squamous cell carcinoma cell line.Q40186736
A phase I study of OGX-011, a 2'-methoxyethyl phosphorothioate antisense to clusterin, in combination with docetaxel in patients with advanced cancerQ40428088
Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy.Q40444331
Targeting chemotherapy-induced VEGF up-regulation by VEGF antisense oligonucleotides in HNSCC cell linesQ40522328
Specific inhibition of the rat ligand-gated ion channel P2X3 function via methoxyethoxy-modified phosphorothioated antisense oligonucleotidesQ40793546
TGF-alpha antisense gene therapy inhibits head and neck squamous cell carcinoma growth in vivoQ40906936
Variable 18F-fluorodeoxyglucose uptake in gastric cancer is associated with different levels of GLUT-1 expressionQ43134569
Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing miceQ43149390
RNA interference in vitro and in vivo using an arginine peptide/siRNA complex systemQ43192622
Folate-mediated targeting of albumin conjugates of paclitaxel obtained through a heterogeneous phase system.Q43284749
Poly(ethylene glycol)-human serum albumin-paclitaxel conjugates: preparation, characterization and pharmacokineticsQ43725891
Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexesQ43938215
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma.Q44260431
Radiotherapy with concurrent docetaxel and carboplatin for head and neck cancerQ44293455
Prevention of radiation-induced oral cavity mucositis by plasmid/liposome delivery of the human manganese superoxide dismutase (SOD2) transgeneQ44324277
Liposomal nanomedicinesQ37039021
HFT-T, a targeting nanoparticle, enhances specific delivery of paclitaxel to folate receptor-positive tumors.Q37069841
Effect of antisense oligodeoxynucleotides glucose transporter-1 on enhancement of radiosensitivity of laryngeal carcinomaQ37121378
Examining expression of folate receptor in squamous cell carcinoma of the head and neck as a target for a novel nanotherapeutic drugQ37135687
Cancer cells survive with survivinQ37185505
A Cell-Targeted Photodynamic Nanomedicine Strategy for Head and Neck CancersQ37190425
Chemotherapy for recurrent and metastatic head and neck cancerQ37297291
Knocking down barriers: advances in siRNA deliveryQ37380671
Multimodal treatment for head and neck cancerQ37383031
Rhomboid domain containing 2 (RHBDD2): a novel cancer-related gene over-expressed in breast cancerQ37419573
Small silencing RNAs: state-of-the-artQ37475724
The forthcoming applications of gold nanoparticles in drug and gene delivery systems.Q37651864
Fluorodeoxyglucose uptake in laryngeal carcinoma is associated with the expression of glucose transporter-1 and hypoxia-inducible-factor-1α and the phosphoinositide 3-kinase/protein kinase B pathwayQ37652530
Tumor-selective delivery of macromolecular drugs via the EPR effect: background and future prospectsQ37732204
Surface plasmon resonance biosensors incorporating gold nanoparticles.Q37993520
Leaky tumor vessels: consequences for tumor stroma generation and for solid tumor therapy.Q37999837
Nanotechnology applied to overcome tumor drug resistanceQ38018774
Photodynamic therapy: oncologic horizonsQ38170385
Therapeutic potentials of gene silencing by RNA interference: principles, challenges, and new strategies.Q38177110
Clinical PD/PDT in North America: An historical reviewQ38232431
Novel aspects of encapsulation and delivery using polymersomesQ38259201
Amphiphilic poly(amino acid) based micelles applied to drug delivery: the in vitro and in vivo challenges and the corresponding potential strategies.Q38286971
Functional comparison of single- and double-stranded siRNAs in mammalian cellsQ38343421
Antitumor effects of epidermal growth factor receptor antisense oligonucleotides in combination with docetaxel in squamous cell carcinoma of the head and neck.Q38348642
Inhibition of ataxia-telangiectasia mutated by antisense oligonucleotide nanoparticles induces radiosensitization of head and neck squamous-cell carcinoma in miceQ38354185
Rhomboid domain containing 1 inhibits cell apoptosis by upregulating AP‐1 activity and its downstream target Bcl‐3Q44441240
HER-2-targeted antisense oligonucleotide results in sensitization of head and neck cancer cells to chemotherapeutic agentsQ44748712
Trends in incidence and prognosis for head and neck cancer in the United States: a site-specific analysis of the SEER databaseQ44849577
Solid-state solubility influences encapsulation and release of hydrophobic drugs from PLGA/PLA nanoparticlesQ44920078
Intraoral manganese superoxide dismutase-plasmid/liposome (MnSOD-PL) radioprotective gene therapy decreases ionizing irradiation-induced murine mucosal cell cycling and apoptosis.Q45059966
Altered expression of epidermal growth factor receptor and estrogen receptor in MCF-7 cells after single and repeated radiation exposuresQ45087628
Gold nanoparticles enhance the radiation therapy of a murine squamous cell carcinomaQ45213619
A phase III randomized study comparing cisplatin and fluorouracil as single agents and in combination for advanced squamous cell carcinoma of the head and neckQ45236091
Epidermal growth factor receptor--mediated stat3 signaling blocks apoptosis in head and neck cancerQ45867493
Intratracheal injection of manganese superoxide dismutase (MnSOD) plasmid/liposomes protects normal lung but not orthotopic tumors from irradiationQ45868906
Inhibition of Human Squamous Cell Carcinoma Growth In Vivo by Epidermal Growth Factor Receptor Antisense RNA Transcribed From the U6 PromoterQ45888433
The first targeted delivery of siRNA in humans via a self-assembling, cyclodextrin polymer-based nanoparticle: from concept to clinic.Q45977543
Hypothesis: using the Warburg effect against cancer by reducing glucose and providing lactateQ46098984
GLUT1 protein expression correlates with unfavourable histologic category and high risk in patients with neuroblastic tumours.Q46180186
Expression of glucose transporter-1 and -3 in the head and neck carcinoma--the correlation of the expression with the biological behaviorsQ46653730
HSP 27 as possible prognostic factor in patients with oral squamous cell carcinomaQ47288557
Defining the drug incorporation properties of PLA-PEG nanoparticles.Q51403198
PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug.Q51475804
Phase II trial of sorafenib in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or nasopharyngeal carcinomaQ52581305
Phagocytic uptake and cytotoxicity of solid lipid nanoparticles (SLN) sterically stabilized with poloxamine 908 and poloxamer 407.Q53008600
Survivin and pAkt as potential prognostic markers in squamous cell carcinoma of the head and neckQ53058252
Role of FDG‐PET as a biological marker for predicting the hypoxic status of tongue cancerQ53193315
Elevated levels of transforming growth factor alpha and epidermal growth factor receptor messenger RNA are early markers of carcinogenesis in head and neck cancer.Q53479014
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivoQ53960627
Glucose transporter 1 (GLUT1) of anaerobic glycolysis as predictive and prognostic values in neoadjuvant chemoradiotherapy and laparoscopic surgery for locally advanced rectal cancerQ54493753
[Effect of survivin antisense oligodeoxynucleotide on carcinoma of larynx in vivo and in vitro].Q54604866
Alcohol Drinking in Never Users of Tobacco, Cigarette Smoking in Never Drinkers, and the Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology ConsortiumQ57559757
Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunitsQ69900353
Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesisQ72393641
Drug delivery in poly(lactide-co-glycolide) nanoparticles surface modified with poloxamer 407 and poloxamine 908: in vitro characterisation and in vivo evaluationQ73448001
Downmodulation of TGF-α protein expression with antisense oligonucleotides inhibits proliferation of head and neck squamous carcinoma but not normal mucosal epithelial cellsQ74346536
Survivin expression in laryngeal squamous cell carcinomas and its prognostic implicationsQ74602420
Head and neck cancerQ77387887
Overexpression of GLUT-1 is associated with resistance to radiotherapy and adverse prognosis in squamous cell carcinoma of the oral cavityQ79506613
Targeted drug delivery via folate receptorsQ80816524
In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in miceQ81697594
Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNAQ82636471
A phase II study of docetaxel and carboplatin with concurrent radiation therapy for locally advanced head and neck cancerQ84509376
Expression of RHBDD1 gene in patients with chronic myeloid leukemia and its clinical significanceQ86364174
Direct gene transfer with DNA-liposome complexes in melanoma: expression, biologic activity, and lack of toxicity in humansQ34345458
Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligandsQ34427646
Overview of ribonucleotide reductase inhibitors: an appealing target in anti-tumour therapyQ34428540
Heat shock proteins in cancer: chaperones of tumorigenesisQ34495261
Hsp27: novel regulator of intracellular redox stateQ34564355
Invited review: Interplay between molecular chaperones and signaling pathways in survival of heat shockQ34564831
Clinical experience of MEK inhibitors in cancer therapyQ34595700
Nanocapsule technology: a review.Q34799194
Protein kinase CK2: structure, regulation and role in cellular decisions of life and deathQ34978734
Sphingosine kinase, sphingosine-1-phosphate, and apoptosisQ35047178
Biodegradable nanoparticles for drug and gene delivery to cells and tissueQ35082117
Noncovalent Functionalization of Carbon Nanovectors with an Antibody Enables Targeted Drug DeliveryQ35177908
Targeted Dendrimer Chemotherapy in an Animal Model for Head and Neck Squamous Cell CarcinomaQ35184402
Protein kinase CK2 in health and disease: CK2: a key player in cancer biologyQ35270830
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivoQ35676433
Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapyQ35749863
Folate-targeted chemotherapyQ35749880
Biologically active sphingolipids in cancer pathogenesis and treatmentQ35852313
Noncovalent assembly of targeted carbon nanovectors enables synergistic drug and radiation cancer therapy in vivoQ35856908
Systemic delivery of siRNA nanoparticles targeting RRM2 suppresses head and neck tumor growth.Q35947017
Impact of tumor-specific targeting on the biodistribution and efficacy of siRNA nanoparticles measured by multimodality in vivo imagingQ35995110
Repopulation of cancer cells during therapy: an important cause of treatment failureQ36167592
Human rhomboid family-1 gene silencing causes apoptosis or autophagy to epithelial cancer cells and inhibits xenograft tumor growthQ36186343
Gene therapy progress and prospects: development of improved lentiviral and retroviral vectors--design, biosafety, and production.Q36186475
Epidermal growth factor receptor directed therapy in head and neck cancerQ36278199
Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptorsQ36405679
Association of elevated protein kinase CK2 activity with aggressive behavior of squamous cell carcinoma of the head and neck.Q36437544
Expression and significance of hypoxia-inducible factor-1α and glucose transporter-1 in laryngeal carcinomaQ36475940
The epidermal growth factor receptor (EGFR) in head and neck cancer: its role and treatment implicationsQ36488138
Programmed drug delivery: nanosystems for tumor targetingQ36810261
Systemic and global toxicities of head and neck treatmentQ36879176
Protein kinase CK2--a key suppressor of apoptosisQ36994133
Expression of folate receptors in nasopharyngeal and laryngeal carcinoma and folate receptor-mediated endocytosis by molecular targeted nanomedicineQ37014465
P275copyright licenseCreative Commons Attribution-NonCommercial-NoDerivativesQ6937225
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectnanoparticleQ61231
head and neck neoplasmsQ18975915
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)187-200
P577publication date2015-01-01
2015-01-12
P13046publication type of scholarly workreview articleQ7318358
P1433published inInternational Journal of Medical SciencesQ10927439
P1476titleNanoparticle-based targeted therapeutics in head-and-neck cancer
P478volume12

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cites work (P2860)
Q94465887Biomimetic Gold Nanoshell-Loaded Macrophage for Photothermal Biomedicine
Q60922841Complete Disaggregation of MCF-7-derived Breast Tumour Spheroids with Very Low Concentrations of α-Mangostin Loaded in CD44 Thioaptamer-tagged Nanoparticles
Q90220710Nanomaterial-based blood-brain-barrier (BBB) crossing strategies
Q50142281Photodynamic therapy in 3D cancer models and the utilisation of nanodelivery systems.
Q36268850Photothermal therapeutic application of gold nanorods-porphyrin-trastuzumab complexes in HER2-positive breast cancer
Q28818470Pigmy MicroRNA: surveillance cops in Therapies kingdom
Q40054092Poly-N-acryloyl-(l-phenylalanine methyl ester) hollow core nanocapsules facilitate sustained delivery of immunomodulatory drugs and exhibit adjuvant properties.
Q30390899Safety and efficacy of quadrapeutics versus chemoradiation in head and neck carcinoma xenograft model
Q64892507True hypopharyngeal carcinosarcoma: a case report and literature review.

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