Research gaps in defining the biological link between HIV risk and hormonal contraception

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Research gaps in defining the biological link between HIV risk and hormonal contraception is …
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scholarly articleQ13442814

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P356DOI10.1111/AJI.12209
P3181OpenCitations bibliographic resource ID5088792
P932PMC publication ID4106985
P698PubMed publication ID24548147

P50authorBetsy C HeroldQ89739748
P2093author name stringKerry Murphy
Susan C. Irvin
P2860cites workInnate immune defences in the human endometriumQ24801159
DC-SIGN, a dendritic cell-specific HIV-1-binding protein that enhances trans-infection of T cellsQ28138968
Differential expression of the natural antimicrobials, beta-defensins 3 and 4, in human endometriumQ28191288
Vaginal microbiome of reproductive-age womenQ28284755
The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cellsQ28302792
Prevalent and incident bacterial vaginosis are associated with sexual and contraceptive behaviours in young Australian womenQ31112477
Molecular identification of bacteria associated with bacterial vaginosis.Q33226498
Cationic polypeptides are required for anti-HIV-1 activity of human vaginal fluidQ33227608
Anti-HIV activity in cervical-vaginal secretions from HIV-positive and -negative women correlate with innate antimicrobial levels and IgG antibodiesQ33627673
Sex steroid hormones, hormonal contraception, and the immunobiology of human immunodeficiency virus-1 infectionQ33779655
Human immunodeficiency virus type 1 attachment to HeLa CD4 cells is CD4 independent and gp120 dependent and requires cell surface heparansQ33782608
A randomized trial to assess anti-HIV activity in female genital tract secretions and soluble mucosal immunity following application of 1% tenofovir gel.Q33808638
Generation of papillomavirus-immortalized cell lines from normal human ectocervical, endocervical, and vaginal epithelium that maintain expression of tissue-specific differentiation proteinsQ41088834
Effects of medroxyprogesterone acetate on gene expression in myometrial explants from pregnant women.Q42906456
Effect of mifepristone on the expression of endometrial secretory leukocyte protease inhibitor in new medroxyprogesterone acetate usersQ43405440
Changes in plasma human immunodeficiency virus type 1 RNA associated with herpes simplex virus reactivation and suppressionQ44226643
Hormonal contraception can suppress natural antimicrobial gene transcription in human endometrium.Q44442528
The effect of one injection of Depo-Provera on the human vaginal epithelium and cervical ectopyQ44865495
Herpes simplex virus type 2 and risk of intrapartum human immunodeficiency virus transmissionQ45407660
Genital tract shedding of herpes simplex virus type 2 in women: effects of hormonal contraception, bacterial vaginosis, and vaginal group B Streptococcus colonizationQ45477038
Vaginal lactobacilli, microbial flora, and risk of human immunodeficiency virus type 1 and sexually transmitted disease acquisitionQ45746359
Progesterone implants enhance SIV vaginal transmission and early virus loadQ45767734
High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques.Q46034053
The effect of progesterone levels and pregnancy on HIV-1 coreceptor expressionQ46162481
Cutting edge: progesterone regulates IFN-alpha production by plasmacytoid dendritic cellsQ46771610
PRO 2000 elicits a decline in genital tract immune mediators without compromising intrinsic antimicrobial activity.Q51065292
Hormonal contraceptive use and female-to-male HIV transmission: a systematic review of the epidemiologic evidence.Q51302460
Female genital-tract HIV load correlates inversely with Lactobacillus species but positively with bacterial vaginosis and Mycoplasma hominis.Q53880710
Variations in the levels of secretory component in human uterine fluid during the menstrual cycleQ71305129
The effect upon the human vaginal histology of the long-term use of the injectable contraceptive Depo-ProveraQ73054855
Depomedroxyprogesterone-induced hypoestrogenism and changes in vaginal flora and epitheliumQ74228757
Oral contraceptive use induces upregulation of the CCR5 chemokine receptor on CD4(+) T cells in the cervical epithelium of healthy womenQ77626176
Synergistic copathogens--HIV-1 and HSV-2Q79808081
Depo-Provera does not alter disease progression in SIVmac-infected female Chinese rhesus macaquesQ33827820
Syndecans serve as attachment receptors for human immunodeficiency virus type 1 on macrophagesQ33845503
Prevalence and risk factors for herpes simplex virus type 2 infection among middle-age women in Brazil and the PhilippinesQ33943791
Progesterone increases susceptibility and decreases immune responses to genital herpes infectionQ34186763
Recurrence of bacterial vaginosis is significantly associated with posttreatment sexual activities and hormonal contraceptive use.Q34317930
Pharmacokinetics of depot medroxyprogesterone acetate contraception.Q34390234
Cervicovaginal Shedding of HIV Type 1 Is Related to Genital Tract Inflammation Independent of Changes in Vaginal MicrobiotaQ34553877
Transfer of IgG in the female genital tract by MHC class I-related neonatal Fc receptor (FcRn) confers protective immunity to vaginal infectionQ34693822
Structure and function of intercellular junctions in human cervical and vaginal mucosal epitheliaQ35068652
Female genital tract secretions inhibit herpes simplex virus infection: correlation with soluble mucosal immune mediators and impact of hormonal contraception.Q35565782
Bacterial vaginosis: Etiology and modalities of treatment-A brief note.Q35646141
Use of hormonal contraceptives and risk of HIV-1 transmission: a prospective cohort studyQ35699938
CCR5 expression is elevated on endocervical CD4+ T cells in healthy postmenopausal womenQ35784816
Cervicovaginal levels of lactoferrin, secretory leukocyte protease inhibitor, and RANTES and the effects of coexisting vaginoses in human immunodeficiency virus (HIV)-seronegative women with a high risk of heterosexual acquisition of HIV infectionQ36095139
Viricidal effect of Lactobacillus acidophilus on human immunodeficiency virus type 1: possible role in heterosexual transmissionQ36230178
Interaction between lactobacilli, bacterial vaginosis-associated bacteria, and HIV Type 1 RNA and DNA Genital shedding in U.S. and Kenyan womenQ36509620
Herpes simplex virus 2 (HSV-2) prevents dendritic cell maturation, induces apoptosis, and triggers release of proinflammatory cytokines: potential links to HSV-HIV synergyQ36559887
Hormonal contraception and HIV-1 infection: medroxyprogesterone acetate suppresses innate and adaptive immune mechanismsQ36628484
Depot medroxyprogesterone acetate increases immune cell numbers and activation markers in human vaginal mucosal tissuesQ36634806
Modelling the global competing risks of a potential interaction between injectable hormonal contraception and HIV riskQ36888158
Herpes simplex virus downregulates secretory leukocyte protease inhibitor: a novel immune evasion mechanismQ36898823
Changes in the soluble mucosal immune environment during genital herpes outbreaksQ36937188
In vivo role of nectin-1 in entry of herpes simplex virus type 1 (HSV-1) and HSV-2 through the vaginal mucosaQ36955176
Bacterial vaginosis and HIV acquisition: a meta-analysis of published studiesQ37211585
Persistence of HIV-1 receptor-positive cells after HSV-2 reactivation is a potential mechanism for increased HIV-1 acquisitionQ37295563
Innate immunity in the human female reproductive tract: endocrine regulation of endogenous antimicrobial protection against HIV and other sexually transmitted infectionsQ37334286
Innate immunity in the vagina (part I): estradiol inhibits HBD2 and elafin secretion by human vaginal epithelial cellsQ37334315
Sex hormone regulation of innate immunity in the female reproductive tract: the role of epithelial cells in balancing reproductive potential with protection against sexually transmitted pathogens.Q37334338
Hormonal contraception and risk of sexually transmitted disease acquisition: results from a prospective studyQ37873613
Effect of hormonal contraceptive methods on HIV disease progression: a systematic review.Q38058410
Hormonal contraception decreases bacterial vaginosis but oral contraception may increase candidiasis: implications for HIV transmissionQ38105449
Differential regulation of endogenous pro-inflammatory cytokine genes by medroxyprogesterone acetate and norethisterone acetate in cell lines of the female genital tract.Q39473447
Cervicovaginal secretions contribute to innate resistance to herpes simplex virus infectionQ40360352
Genital herpes simplex virus infection and perinatal transmission of human immunodeficiency virusQ40368653
Syndecan captures, protects, and transmits HIV to T lymphocytesQ40677051
Differential expression of immunobiological mediators by immortalized human cervical and vaginal epithelial cellsQ40978781
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbirth controlQ122224
P304page(s)228-35
P577publication date2014-08-01
P1433published inAmerican Journal of Reproductive ImmunologyQ15761228
P1476titleResearch gaps in defining the biological link between HIV risk and hormonal contraception
P478volume72

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cites work (P2860)
Q40632328A Depot Medroxyprogesterone Acetate Dose That Models Human Use and Its Effect on Vaginal SHIV Acquisition Risk
Q92496129Aberrant cervical innate immunity predicts onset of dysbiosis and sexually transmitted infections in women of reproductive age
Q41074827Analysis of putative mucosal SHIV susceptibility factors during repeated DMPA treatments in pigtail macaques
Q47731889Bacterial vaginosis modifies the association between hormonal contraception and HIV acquisition
Q91973442Crosstalk Between Female Gonadal Hormones and Vaginal Microbiota Across Various Phases of Women's Gynecological Lifecycle
Q36921893Effect of hormonal contraception on the function of plasmacytoid dendritic cells and distribution of immune cell populations in the female reproductive tract
Q38851686Effects of injectable progestogen contraception versus the copper intrauterine device on HIV acquisition: sub-study of a pragmatic randomised controlled trial
Q37651577Effects of the levonorgestrel-releasing intrauterine device on the immune microenvironment of the human cervix and endometrium
Q30387557Factors Driving the HIV Epidemic in Southern Africa
Q34117651Gonadal function and reproductive health in women with human immunodeficiency virus infection
Q64133816HIV risk associated with serum medroxyprogesterone acetate levels among women in East and southern Africa
Q47198102Hormonal Contraception and HIV-1 Acquisition: Biological Mechanisms
Q30660068Hormonal contraceptive use and women's risk of HIV acquisition: a meta-analysis of observational studies
Q50956725Interpretation, communication, and mechanisms of associations between injectable contraception and HIV risk - Authors' reply.
Q36828511Intravaginal practices among HIV-negative female sex workers along the US-Mexico border and their implications for emerging HIV prevention interventions
Q49838895Is a lower-dose, subcutaneous contraceptive injectable containing depot medroxyprogesterone acetate likely to impact women's risk of HIV?
Q36068904Levels of Genital Tract Defensins and Cytokines Differ between HIV-Uninfected US and African Women
Q40515915Levonorgestrel in contraceptives and multipurpose prevention technologies: does this progestin increase HIV risk or interact with antiretrovirals?
Q37280240Medroxyprogesterone acetate and levonorgestrel increase genital mucosal permeability and enhance susceptibility to genital herpes simplex virus type 2 infection
Q35784803Medroxyprogesterone acetate impairs human dendritic cell activation and function
Q35208283Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk
Q89664038Norethisterone Enanthate Increases Mouse Susceptibility to Genital Infection with Herpes Simplex Virus Type 2 and HIV Type 1
Q39237289Progesterone-based compounds affect immune responses and susceptibility to infections at diverse mucosal sites
Q35172396Progesterone-based intrauterine device use is associated with a thinner apical layer of the human ectocervical epithelium and a lower ZO-1 mRNA expression.
Q36284595Relationship of Estimated SHIV Acquisition Time Points During the Menstrual Cycle and Thinning of Vaginal Epithelial Layers in Pigtail Macaques
Q40047233Role of sex hormones and the vaginal microbiome in susceptibility and mucosal immunity to HIV-1 in the female genital tract.
Q39207555Use of injectable hormonal contraception and HSV-2 acquisition in a cohort of female sex workers in Vancouver, Canada
Q38157367Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques.

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