Angiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives

scientific article

Angiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/OTT.S46457
P8608Fatcat IDrelease_myzaiy5mpfbvfkghvbjcr7njua
P3181OpenCitations bibliographic resource ID3694484
P932PMC publication ID4211614
P698PubMed publication ID25364263
P5875ResearchGate publication ID267754353

P50authorFilip JankuQ73569186
P2093author name stringAhmed Kaseb
Manojkumar Bupathi
P2860cites workAngiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesisQ24313372
Biologic significance of angiopoietin-2 expression in human hepatocellular carcinomaQ24563486
Molecular therapies in hepatocellular carcinoma: what can we target?Q27025381
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancerQ27860681
Sorafenib in advanced hepatocellular carcinomaQ27861075
Hepatocellular carcinomaQ29615765
The biology of vascular endothelial growth factorQ29615946
Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growthQ33732486
Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5)beta(1) integrin-mediated pathwayQ33896998
Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencingQ33917547
Estimating the world cancer burden: Globocan 2000Q34518922
Angiopoietin-2 is implicated in the regulation of tumor angiogenesisQ35746320
Antiangiogenic gene therapy targeting the endothelium-specific receptor tyrosine kinase Tie2Q36223383
Pancreatic cancer: an updateQ36790158
Targeting the angiopoietin/Tie2 pathway: cutting tumor vessels with a double-edged sword?Q37970070
Direct actions of angiopoietin-1 on human endothelium: evidence for network stabilization, cell survival, and interaction with other angiogenic growth factors.Q52534158
Rapid decrease in delivery of chemotherapy to tumors after anti-VEGF therapy: implications for scheduling of anti-angiogenic drugsQ53179408
TIE2-expressing monocytes as a diagnostic marker for hepatocellular carcinoma correlates with angiogenesis.Q54496036
Plasma Biomarkers as Predictors of Outcome in Patients with Advanced Hepatocellular CarcinomaQ54526554
Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells.Q54597476
Angiopoietin-2 Serum Levels Are Elevated in Patients With Liver Cirrhosis and Hepatocellular CarcinomaQ58099091
Expression of angiopoietin-2 gene and its receptor Tie2 in hepatocellular carcinomaQ78828703
Angiopoietin-2 impairs revascularization after limb ischemiaQ80412365
mTOR as a Potential Target for the Prevention and Treatment of Hepatocellular CarcinomaQ38032897
Angiopoietin-2: an attractive target for improved antiangiogenic tumor therapyQ38087230
Antiangiogenic therapies: going beyond their limitsQ38172781
Overexpression of VEGF and angiopoietin 2: a key to high vascularity of hepatocellular carcinoma?Q38520141
Angiotensin II Induces Angiogenic Factors Production Partly Via AT1/JAK2/STAT3/SOCS3 Signaling Pathway in MHCC97H CellsQ39344956
Efficacy of Bevacizumab plus Erlotinib for Advanced Hepatocellular Carcinoma and Predictors of Outcome: Final Results of a Phase II TrialQ39653331
Resistance to Targeted Therapies: Refining Anticancer Therapy in the Era of Molecular OncologyQ39919528
Tie2 vascular endothelial receptor expression and function in hepatocellular carcinomaQ43933938
Safety, pharmacokinetics, and antitumor activity of AMG 386, a selective angiopoietin inhibitor, in adult patients with advanced solid tumorsQ44649604
Serum levels of angiogenic and anti-angiogenic factors: their prognostic relevance in locally advanced hepatocellular carcinomaQ45339888
Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer.Q45866300
Overexpression of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinomaQ47741987
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)1927-32
P577publication date2014-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inOncoTargets and TherapyQ7092081
P1476titleAngiopoietin 2 as a therapeutic target in hepatocellular carcinoma treatment: current perspectives
P478volume7

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cites work (P2860)
Q28553513A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells
Q41574359A Review of Anti-Angiogenic Targets for Monoclonal Antibody Cancer Therapy
Q36825943A double suicide gene system driven by vascular endothelial growth factor promoter selectively kills human hepatocellular carcinoma cells
Q61454351Clinical and prognostic significance of circulating levels of angiopoietin-1 and angiopoietin-2 in hepatocellular carcinoma
Q36313998From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma
Q41446079Liposomal curcumin inhibits hypoxia-induced angiogenesis after transcatheter arterial embolization in VX2 rabbit liver tumors
Q60936609Molecular Mechanisms Involved in HCC Recurrence after Direct-Acting Antiviral Therapy
Q36121903Prognostic value of angiopoietin-2 in non-small cell lung cancer patients: a meta-analysis
Q38693339Serum biomarker analysis in patients with recurrent spontaneous abortion

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