scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Hyun-Ock Pae | Q122925225 |
Yong Son | Q122925241 | ||
Ju Hwan Lee | Q122925249 | ||
Hun Taeg Chung | Q86192882 | ||
P2860 | cites work | Free radicals and antioxidants in normal physiological functions and human disease | Q21710698 |
Oxidative stress causes enhanced endothelial cell injury in human heme oxygenase-1 deficiency | Q22008645 | ||
Curcumin activates the haem oxygenase-1 gene via regulation of Nrf2 and the antioxidant-responsive element | Q24529933 | ||
Ferritin: a cytoprotective antioxidant strategem of endothelium | Q28264360 | ||
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes | Q28575190 | ||
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance | Q29012156 | ||
Heme oxygenase-derived carbon monoxide restores vascular function in type 1 diabetes | Q29347162 | ||
Signal transduction by reactive oxygen species | Q29615230 | ||
p38 mitogen-activated protein kinase: a critical node linking insulin resistance and cardiovascular diseases in type 2 diabetes mellitus | Q30447995 | ||
Curcumin: an anti-inflammatory molecule from a curry spice on the path to cancer treatment. | Q34027184 | ||
Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training | Q34031701 | ||
Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. | Q51753643 | ||
Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways. | Q52926548 | ||
Carbon monoxide induces heme oxygenase-1 via activation of protein kinase R-like endoplasmic reticulum kinase and inhibits endothelial cell apoptosis triggered by endoplasmic reticulum stress. | Q53529663 | ||
Metabolism and anticancer activity of the curcumin analogue, dimethoxycurcumin. | Q53569563 | ||
The effect of sepsis on the oxidation of carbohydrate and fat. | Q54506145 | ||
Carbon monoxide, a reaction product of heme oxygenase-1, suppresses the expression of C-reactive protein by endoplasmic reticulum stress through modulation of the unfolded protein response. | Q54585180 | ||
Cobalt-protoporphyrin suppresses thyroid and testicular hormone concentrations in rat serum: a novel action of this synthetic heme analogue | Q68953596 | ||
A model of cytochrome P-450-centered hepatic dysfunction in drug metabolism induced by cobalt-protoporphyrin administration | Q69258594 | ||
The comparative abilities of inorganic cobalt and cobalt-protoporphyrin to affect copper metabolism and elevate plasma ceruloplasmin | Q72228589 | ||
Heme oxygenase-1 mediates the anti-inflammatory effect of interleukin-10 in mice | Q77719701 | ||
Comparative effects of curcuminoids on endothelial heme oxygenase-1 expression: ortho-methoxy groups are essential to enhance heme oxygenase activity and protection | Q80213574 | ||
Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity | Q80264331 | ||
Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin | Q80349552 | ||
Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance | Q38292224 | ||
Involvement of heme oxygenase-1 expression in neuroprotection by piceatannol, a natural analog and a metabolite of resveratrol, against glutamate-mediated oxidative injury in HT22 neuronal cells | Q39146785 | ||
Resveratrol analog-3,5,4'-trimethoxy-trans-stilbene inhibits invasion of human lung adenocarcinoma cells by suppressing the MAPK pathway and decreasing matrix metalloproteinase-2 expression. | Q39906700 | ||
Differential effects of IRS1 phosphorylated on Ser307 or Ser632 in the induction of insulin resistance by oxidative stress. | Q40245739 | ||
Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway | Q40890343 | ||
Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression | Q41862754 | ||
Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes. | Q42445706 | ||
Molecular mechanisms by which saturated fatty acids modulate TNF-α expression in mouse macrophage lineage | Q42476450 | ||
Activation of NF-kappaB by palmitate in endothelial cells: a key role for NADPH oxidase-derived superoxide in response to TLR4 activation | Q42626543 | ||
The protective effects of oxyresveratrol imine derivative against hydrogen peroxide-induced cell death in PC12 cells | Q42713453 | ||
Dynamics of haem oxygenase-1 expression and bilirubin production in cellular protection against oxidative stress. | Q42996841 | ||
Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats | Q43120253 | ||
Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive rats | Q43218244 | ||
The heme oxygenase system attenuates pancreatic lesions and improves insulin sensitivity and glucose metabolism in deoxycorticosterone acetate hypertension | Q43253217 | ||
Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism | Q44564039 | ||
Endoplasmic reticulum stress stimulates heme oxygenase-1 gene expression in vascular smooth muscle. Role in cell survival | Q45152588 | ||
Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta | Q45282771 | ||
Resveratrol toxicity: effects on risk factors for atherosclerosis and hepatic oxidative stress in standard and high-fat diets | Q46082502 | ||
Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats | Q46116568 | ||
Upregulation of the heme oxygenase system ameliorates postprandial and fasting hyperglycemia in type 2 diabetes | Q46125858 | ||
Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes | Q46135112 | ||
The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways | Q46184635 | ||
Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats | Q46187621 | ||
Antioxidant mechanism of heme oxygenase-1 involves an increase in superoxide dismutase and catalase in experimental diabetes | Q46430428 | ||
Resveratrol upregulates heme oxygenase-1 expression via activation of NF-E2-related factor 2 in PC12 cells | Q46481176 | ||
Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats | Q46542331 | ||
Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells | Q46707414 | ||
Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways | Q46769228 | ||
Cobalt ameliorates renal injury in an obese, hypertensive type 2 diabetes rat model | Q46925608 | ||
Regulation of food intake and body weight in rats by the synthetic heme analogue cobalt protoporphyrin | Q47422155 | ||
Oxidative stress in health and disease: the therapeutic potential of Nrf2 activation | Q34226575 | ||
Biological activity of piceatannol: leaving the shadow of resveratrol. | Q34235213 | ||
Roles of heme oxygenase-1 in curcumin-induced growth inhibition in rat smooth muscle cells | Q34580732 | ||
Dimethoxycurcumin, a Synthetic Curcumin Analogue, Induces Heme Oxygenase-1 Expression through Nrf2 Activation in RAW264.7 Macrophages | Q34603783 | ||
Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome | Q34997524 | ||
Hydrogen peroxide as second messenger in lymphocyte activation | Q35007083 | ||
Chronic HO-1 induction with cobalt protoporphyrin (CoPP) treatment increases oxygen consumption, activity, heat production and lowers body weight in obese melanocortin-4 receptor-deficient mice | Q35115604 | ||
Laboratory and clinical studies of cancer chemoprevention by antioxidants in berries | Q35636550 | ||
Bilirubin: an endogenous product of heme degradation with both cytotoxic and cytoprotective properties | Q35842947 | ||
Enhancement of curcumin oral absorption and pharmacokinetics of curcuminoids and curcumin metabolites in mice | Q36011080 | ||
Heme oxygenase gene targeting to adipocytes attenuates adiposity and vascular dysfunction in mice fed a high-fat diet | Q36178293 | ||
Inflammatory mechanisms in the regulation of insulin resistance | Q36409227 | ||
Regulation of inflammation and redox signaling by dietary polyphenols | Q36571463 | ||
Heme oxygenase 1 is required for mammalian iron reutilization | Q36601831 | ||
Signaling mechanisms of a water soluble curcumin derivative in experimental type 1 diabetes with cardiomyopathy. | Q36698572 | ||
A systematic review of oxidative stress and safety of antioxidants in diabetes: focus on islets and their defense | Q36800711 | ||
Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin | Q36836199 | ||
Metabolic syndrome and adipose tissue: new clinical aspects and therapeutic targets | Q36879401 | ||
Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase | Q36980730 | ||
Strategic targets to induce neovascularization by resveratrol in hypercholesterolemic rat myocardium: role of caveolin-1, endothelial nitric oxide synthase, hemeoxygenase-1, and vascular endothelial growth factor | Q36984711 | ||
Heme oxygenase: a target gene for anti-diabetic and obesity | Q37090254 | ||
Integrative survival response evoked by heme oxygenase-1 and heme metabolites | Q37188532 | ||
Effects of Resveratrol and trans-3,5,4'-Trimethoxystilbene on Glutamate-Induced Cytotoxicity, Heme Oxygenase-1, and Sirtuin 1 in HT22 Neuronal Cells | Q37224583 | ||
Heme oxygenase-1 induction remodels adipose tissue and improves insulin sensitivity in obesity-induced diabetic rats | Q37350417 | ||
Molecular mechanisms involved in obesity-associated insulin resistance: therapeutical approach. | Q37578545 | ||
Integration of ER stress, oxidative stress and the inflammatory response in health and disease | Q37724635 | ||
Role of heme oxygenase in preserving vascular bioactive NO. | Q37780323 | ||
Heme oxygenase-1 comes back to endoplasmic reticulum | Q37811296 | ||
Polyphenols: planting the seeds of treatment for the metabolic syndrome | Q37848999 | ||
Dietary phytochemicals and their potential effects on obesity: a review | Q37907457 | ||
Sensing damage by the NLRP3 inflammasome | Q37925073 | ||
Crosstalk between advanced glycation and endoplasmic reticulum stress: emerging therapeutic targeting for metabolic diseases | Q38003116 | ||
New insights into ER stress-induced insulin resistance. | Q38024445 | ||
Metabolic syndrome, insulin resistance, and roles of inflammation--mechanisms and therapeutic targets | Q38027826 | ||
Metabolic syndrome in youth: current insights and novel serum biomarkers | Q38066238 | ||
P275 | copyright license | Creative Commons Attribution 3.0 Unported | Q14947546 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | curcumin | Q312266 |
resveratrol | Q407329 | ||
stilbenoid | Q526360 | ||
metabolic disease | Q2351083 | ||
heme oxygenase 1 | Q5631153 | ||
P304 | page(s) | 639541 | |
P577 | publication date | 2013-01-01 | |
2013-09-11 | |||
P1433 | published in | Oxidative medicine and cellular longevity | Q26840015 |
P1476 | title | Therapeutic roles of heme oxygenase-1 in metabolic diseases: curcumin and resveratrol analogues as possible inducers of heme oxygenase-1 | |
P478 | volume | 2013 |
Q52564097 | A review on heme oxygenase-1 induction: is it a necessary evil. |
Q38434569 | Amomum tsao-ko suppresses lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages via Nrf2-dependent heme oxygenase-1 expression |
Q26799265 | Anticancer drugs for the modulation of endoplasmic reticulum stress and oxidative stress |
Q35145862 | Antioxidant and anti-inflammatory activities of berberine in the treatment of diabetes mellitus |
Q30401142 | Bach1 deficiency reduces severity of osteoarthritis through upregulation of heme oxygenase-1 |
Q46731720 | Cilostazol attenuates murine hepatic ischemia and reperfusion injury via heme oxygenase-dependent activation of mitochondrial biogenesis |
Q53589405 | Curcumin ameliorates asthmatic airway inflammation by activating nuclear factor-E2-related factor 2/haem oxygenase (HO)-1 signalling pathway. |
Q36801738 | Evidence that the capacity of nongenotoxic carcinogens to induce oxidative stress is subject to marked variability. |
Q38935541 | Gastrodin Ameliorates Oxidative Stress and Proinflammatory Response in Nonalcoholic Fatty Liver Disease through the AMPK/Nrf2 Pathway |
Q46374469 | Glioprotective Effect of Resveratrol: an Emerging Therapeutic Role for Oligodendroglial Cells |
Q35849894 | Grape pomace extract exerts antioxidant effects through an increase in GCS levels and GST activity in muscle and endothelial cells. |
Q39249545 | Heme as a Target for Therapeutic Interventions |
Q60911559 | Heme oxygenase 1 facilitates cell proliferation via the B-Raf-ERK signaling pathway in melanoma |
Q37448506 | Induction of heme oxygenase-1 with dietary quercetin reduces obesity-induced hepatic inflammation through macrophage phenotype switching |
Q28553110 | Modification of Caffeic Acid with Pyrrolidine Enhances Antioxidant Ability by Activating AKT/HO-1 Pathway in Heart |
Q64941766 | Naturally derived Heme-Oxygenase 1 inducers attenuate inflammatory responses in human dendritic cells and T cells: relevance for psoriasis treatment. |
Q90309042 | New Arylethanolimidazole Derivatives as HO-1 Inhibitors with Cytotoxicity against MCF-7 Breast Cancer Cells |
Q39193649 | Protective effects of curcumin against mercury-induced hepatic injuries in rats, involvement of oxidative stress antagonism, and Nrf2-ARE pathway activation |
Q35587158 | Resveratrol ameliorates renal damage, increases expression of heme oxygenase-1, and has anti-complement, anti-oxidative, and anti-apoptotic effects in a murine model of membranous nephropathy |
Q28396841 | Saponins from Aralia taibaiensis attenuate D-galactose-induced aging in rats by activating FOXO3a and Nrf2 pathways |
Q51318932 | Sea cucumber peptides exert anti-inflammatory activity through suppressing NF-κB and MAPK and inducing HO-1 in RAW264.7 macrophages. |
Q61053748 | Subversion of the Heme Oxygenase-1 Antiviral Activity by Zika Virus |
Q87856672 | Sulforaphane Attenuated the Pro-Inflammatory State Induced by Hydrogen Peroxide in SH-SY5Y Cells Through the Nrf2/HO-1 Signaling Pathway |
Q26999376 | Systemic and renal oxidative stress in the pathogenesis of hypertension: modulation of long-term control of arterial blood pressure by resveratrol |
Q64354593 | The Pathogenesis of Diabetes Mellitus by Oxidative Stress and Inflammation: Its Inhibition by Berberine |
Q38915619 | The oxysterol 27-hydroxycholesterol increases oxidative stress and regulate Nrf2 signaling pathway in astrocyte cells |
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