Endogenous allosteric modulators of G protein-coupled receptors

scientific article

Endogenous allosteric modulators of G protein-coupled receptors is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1124/JPET.114.221606
P8608Fatcat IDrelease_3xpg6o3mgfdtzc23fg2c52275y
P3181OpenCitations bibliographic resource ID1394718
P698PubMed publication ID25650376
P5875ResearchGate publication ID272075364

P50authorArthur ChristopoulosQ18977850
Patrick M. SextonQ39936838
Celine ValantQ56938593
Emma T van der WesthuizenQ82704855
P2093author name stringP. M. Sexton
A. Christopoulos
C. Valant
E. T. van der Westhuizen
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectG protein-coupled receptorQ38173
P304page(s)246-260
P577publication date2015-05-01
P1433published inJournal of Pharmacology and Experimental TherapeuticsQ1500272
P1476titleEndogenous allosteric modulators of G protein-coupled receptors
P478volume353

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cites work (P2860)
Q47935295A kinetic view of GPCR allostery and biased agonism
Q36178342Allosteric Communication Disrupted by a Small Molecule Binding to the Imidazole Glycerol Phosphate Synthase Protein-Protein Interface.
Q38705545Allosteric Inhibition of Serotonin 5-HT7 Receptors by Zinc Ions
Q26747395Allosteric Modulation of Chemoattractant Receptors
Q41560616Allosteric Modulators of the CB1 Cannabinoid Receptor: A Structural Update Review.
Q53082766Allosteric modulation as a unifying mechanism for receptor function and regulation.
Q41195003Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis
Q38588798Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives
Q64073208Binding kinetics of ligands acting at GPCRs
Q26745261Cannabinoid receptor type-1: breaking the dogmas
Q40168206Cholecystokinin responsiveness varies across the population dependent on metabolic phenotype.
Q93162304Cinacalcet corrects biased allosteric modulation of CaSR by AHH autoantibody
Q37407999Concentration-Dependent Dual Mode of Zn Action at Serotonin 5-HT1A Receptors: In Vitro and In Vivo Studies
Q52604833Design, Synthesis, and Characterization of 4-Undecylpiperidine-2-carboxamides as Positive Allosteric Modulators of the Serotonin (5-HT) 5-HT2C Receptor.
Q92295079Detergent- and phospholipid-based reconstitution systems have differential effects on constitutive activity of G-protein-coupled receptors
Q40994323Differential modulation of the lactisole 'Sweet Water Taste' by sweeteners
Q35999789Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.
Q41683026Glutamine up-regulates MAPK phosphatase-1 induction via activation of Ca2+→ ERK cascade pathway
Q49463637Gs- versus Golf-dependent functional selectivity mediated by the dopamine D1 receptor.
Q43757698How Ligands Illuminate GPCR Molecular Pharmacology
Q92572055Illuminating the Onco-GPCRome: Novel G protein-coupled receptor-driven oncocrine networks and targets for cancer immunotherapy
Q53831234Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations.
Q47749024Medium-Throughput Screen of Microbially Produced Serotonin via a G-Protein-Coupled Receptor-Based Sensor.
Q38690069Metabotropic glutamate receptor 5 - a promising target in drug development and neuroimaging
Q47293279Molecular mechanisms of allosteric probe dependence in μ opioid receptor
Q28081112Novel Allosteric Modulators of G Protein-coupled Receptors
Q47348671Opportunities and Challenges in the Discovery of Allosteric Modulators of GPCRs
Q41534560Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage
Q47301262Pharmacological Evidence for a Putative Conserved Allosteric Site on Opioid Receptors.
Q90183037Plasticity in striatal dopamine release is governed by release-independent depression and the dopamine transporter
Q37183072Practical Strategies and Concepts in GPCR Allosteric Modulator Discovery: Recent Advances with Metabotropic Glutamate Receptors
Q52737158Prediction of consensus binding mode geometries for related chemical series of positive allosteric modulators of adenosine and muscarinic acetylcholine receptors.
Q38451155Quantitative analysis of receptor allosterism and its implication for drug discovery
Q53283601S-Nitrosylation of β-Arrestins Biases Receptor Signaling and Confers Ligand Independence.
Q50207906Structural Connection between Activation Microswitch and Allosteric Sodium Site in GPCR Signaling.
Q59082343Structural insights into G-protein-coupled receptor allostery
Q36673733The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1.
Q47103274Three classes of ligands each bind to distinct sites on the orphan G protein-coupled receptor GPR84.

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