Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis

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Thrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis is …
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scholarly articleQ13442814

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P356DOI10.7150/THNO.14514
P3181OpenCitations bibliographic resource ID2974069
P932PMC publication ID4805666
P698PubMed publication ID27022419

P50authorChristoph E. HagemeyerQ41769331
Karlheinz PeterQ47504540
Xiaowei WangQ58312038
P2093author name stringJan David Hohmann
Jathushan Palasubramaniam
Bock Lim
Yung Chih Chen
Yannik Gkanatsas
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Sonothrombolysis of intra-catheter aged venous thrombi using microbubble enhancement and guided three-dimensional ultrasound pulsesQ30474318
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Coronary and microvascular thrombolysis with guided diagnostic ultrasound and microbubbles in acute ST segment elevation myocardial infarctionQ35608036
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Properties, characteristics and applications of microbubbles for sonothrombolysis.Q38176653
Cardiovascular drug delivery with ultrasound and microbubblesQ38187761
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Thrombus-targeted perfluorocarbon-containing liposomal bubbles for enhancement of ultrasonic thrombolysis: in vitro and in vivo study.Q44077486
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Dual-contrast molecular imaging allows noninvasive characterization of myocardial ischemia/reperfusion injury after coronary vessel occlusion in mice by magnetic resonance imaging.Q51073149
GPIIb/IIIa inhibitors: from bench to bedside and back to bench again.Q51625353
In vivo clot lysis of human thrombus with intravenous abciximab immunobubbles and ultrasound.Q51732892
Towards effective and safe thrombolysis and thromboprophylaxis: preclinical testing of a novel antibody-targeted recombinant plasminogen activator directed against activated platelets.Q51750193
Dissolution of thrombotic arterial occlusion by high intensity, low frequency ultrasound and dodecafluoropentane emulsion: an in vitro and in vivo study.Q52526631
Noninvasive in vivo clot dissolution without a thrombolytic drug: recanalization of thrombosed iliofemoral arteries by transcutaneous ultrasound combined with intravenous infusion of microbubbles.Q52528869
High-frequency ultrasound-guided disruption of glycoprotein VI-targeted microbubbles targets atheroprogressison in mice.Q52654271
In vivo thrombolysis with targeted microbubbles loading tissue plasminogen activator in a rabbit femoral artery thrombus model.Q53589220
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Ultrasound-Enhanced Systemic Thrombolysis for Acute Ischemic StrokeQ57757056
Thrombolytic enhancement with perfluorocarbon-exposed sonicated dextrose albumin microbubblesQ71728132
Albumin Microbubble Echo-Contrast Material as an Enhancer for Ultrasound Accelerated ThrombolysisQ71993125
Flow cytometric monitoring of glycoprotein IIb/IIIa blockade and platelet function in patients with acute myocardial infarction receiving reteplase, abciximab, and ticlopidine: continuous platelet inhibition by the combination of abciximab and ticloQ72998287
Construction and functional evaluation of a single-chain antibody fusion protein with fibrin targeting and thrombin inhibition after activation by factor XaQ73544076
Targeting ligand-induced binding sites on GPIIb/IIIa via single-chain antibody allows effective anticoagulation without bleeding time prolongationQ79830051
Magnetic resonance imaging contrast agent targeted toward activated platelets allows in vivo detection of thrombosis and monitoring of thrombolysisQ81508480
Efficacy and safety of once weekly subcutaneous idrabiotaparinux in the treatment of patients with symptomatic deep venous thrombosisQ85193701
Single-chain antibody conjugated to a cage amine chelator and labeled with positron-emitting copper-64 for diagnostic imaging of activated plateletsQ88226626
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectthrombosisQ261327
microbubbleQ6839290
P304page(s)726-738
P577publication date2016-03-20
P1433published inTheranosticsQ21051383
P1476titleThrombus-Targeted Theranostic Microbubbles: A New Technology towards Concurrent Rapid Ultrasound Diagnosis and Bleeding-free Fibrinolytic Treatment of Thrombosis
P478volume6

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