Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure

scientific article (publication date: 2015)

Directed Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure is …
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scholarly articleQ13442814

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P819ADS bibcode2015PLoSO..1033238C
P356DOI10.1371/JOURNAL.PONE.0133238
P3181OpenCitations bibliographic resource ID3913976
P932PMC publication ID4519179
P698PubMed publication ID26222054
P5875ResearchGate publication ID280587047

P2093author name stringGail S Prins
Esther L Calderon-Gierszal
P2860cites workHormones and endocrine-disrupting chemicals: low-dose effects and nonmonotonic dose responsesQ24613799
Developmental exposure to estradiol and bisphenol A increases susceptibility to prostate carcinogenesis and epigenetically regulates phosphodiesterase type 4 variant 4Q24648201
Parent bisphenol A accumulation in the human maternal-fetal-placental unitQ24811377
Cancer etiology. Variation in cancer risk among tissues can be explained by the number of stem cell divisionsQ26261171
Cancer statistics, 2013Q27860762
Embryonic stem cell lines derived from human blastocystsQ27861010
Generation of a prostate from a single adult stem cellQ28298344
Urinary, circulating, and tissue biomonitoring studies indicate widespread exposure to bisphenol AQ28382768
Impact of early-life bisphenol A exposure on behavior and executive function in childrenQ28393429
Neonatal exposure to estradiol/bisphenol A alters promoter methylation and expression of Nsbp1 and Hpcal1 genes and transcriptional programs of Dnmt3a/b and Mbd2/4 in the rat prostate gland throughout lifeQ28567904
Defects of prostate development and reproductive system in the estrogen receptor-alpha null male miceQ28585567
Elevated androgens and prolactin in aromatase-deficient mice cause enlargement, but not malignancy, of the prostate glandQ28587030
Human exposure to bisphenol A (BPA)Q29547406
Large effects from small exposures. III. Endocrine mechanisms mediating effects of bisphenol A at levels of human exposureQ29615567
Determination of bisphenol A concentrations in human biological fluids reveals significant early prenatal exposureQ29617316
Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic developmentQ29617978
Adipogenic effects of a combination of the endocrine-disrupting compounds bisphenol A, diethylhexylphthalate, and tributyltinQ30317528
Estrogen-initiated transformation of prostate epithelium derived from normal human prostate stem-progenitor cellsQ30426649
Bisphenol-A (BPA), BPA glucuronide, and BPA sulfate in midgestation umbilical cord serum in a northern and central California population.Q30562196
Low doses of the endocrine disruptor bisphenol-A and the native hormone 17beta-estradiol rapidly activate transcription factor CREB.Q44122086
Leaching of bisphenol A (BPA) to seawater from polycarbonate plastic and its degradation by reactive oxygen speciesQ44314708
Association of fetal hormone levels with stem cell potential: evidence for early life roots of human cancer.Q45234588
Effects of estrogens on proliferation and differentiation of neural stem/progenitor cellsQ46492598
Canonical Wnts, specifically Wnt-10b, show ability to maintain dermal papilla cellsQ47856465
Prostate-specific and androgen-dependent expression of a novel homeobox geneQ48056768
Testosterone stimulates growth and secretory activity of the female prostate in the adult gerbil (Meriones unguiculatus).Q51804675
Measurement of bisphenol A concentrations in human colostrum.Q52572799
Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes.Q52620868
Synthetic strogenic Agents without the Phenanthrene NucleusQ55954149
Prostate antigen: A new potential marker for prostatic cancerQ72645674
Fetal bisphenol A exposure: concentration of conjugated and unconjugated bisphenol A in amniotic fluid in the second and third trimestersQ83931724
Androgen receptor localization in different cell types of the adult rat prostateQ33472917
Molecular signaling pathways that regulate prostate gland developmentQ33666315
EGF receptor signaling in prostate morphogenesis and tumorigenesisQ33743859
A round robin approach to the analysis of bisphenol A (BPA) in human blood samples.Q33789200
The female prostate and prostate-specific antigen. Immunohistochemical localization, implications of this prostate marker in women and reasons for using the term "prostate" in the human femaleQ33833946
Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivoQ33914421
Bisphenol A promotes human prostate stem-progenitor cell self-renewal and increases in vivo carcinogenesis in human prostate epitheliumQ34039564
Environmental estrogens: health implications for humans and wildlifeQ34062352
Bisphenol A: an endocrine disruptor with widespread exposure and multiple effectsQ34186815
Roles of the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.Q34280320
Bisphenol A and human health: a review of the literatureQ34367940
Stem cells and their nichesQ34507142
Serum bisphenol A pharmacokinetics and prostate neoplastic responses following oral and subcutaneous exposures in neonatal Sprague-Dawley ratsQ34553299
Similarity of Bisphenol A Pharmacokinetics in Rhesus Monkeys and Mice: Relevance for Human ExposureQ34623620
Induced pluripotency of human prostatic epithelial cells.Q34745924
The role of CD133 in normal human prostate stem cells and malignant cancer-initiating cellsQ34773058
Estrogenic exposure alters the spermatogonial stem cells in the developing testis, permanently reducing crossover levels in the adultQ35007296
Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tractQ35226270
Oral contraceptive use is associated with prostate cancer: an ecological studyQ35564878
Developmental estrogen exposures predispose to prostate carcinogenesis with agingQ35903630
Nongenomic actions of low concentration estrogens and xenoestrogens on multiple tissues.Q36003029
Exposure of Human Prostaspheres to Bisphenol A Epigenetically Regulates SNORD Family Noncoding RNAs via Histone ModificationQ36164314
Visualization and quantification of mouse prostate development by in situ hybridizationQ36236528
The R-spondin family of proteins: emerging regulators of WNT signalingQ36392765
Fetal liver bisphenol A concentrations and biotransformation gene expression reveal variable exposure and altered capacity for metabolism in humansQ36625649
The role of estrogens in normal and abnormal development of the prostate glandQ36721715
Bisphenol-A: an estrogenic substance is released from polycarbonate flasks during autoclavingQ36784179
A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cellsQ37286523
The role of WNT10B in physiology and diseaseQ37859090
Effect of low dose bisphenol A on the early differentiation of human embryonic stem cells into mammary epithelial cellsQ39198022
The endocrinology and developmental biology of the prostateQ39669602
Formation of human prostate tissue from embryonic stem cellsQ40314025
Prostatic growth and development are regulated by FGF10.Q41679731
Modelling human development and disease in pluripotent stem-cell-derived gastric organoidsQ41680408
Directed differentiation of human pluripotent stem cells into intestinal tissue in vitroQ41770080
Reproductive malformation of the male offspring following maternal exposure to estrogenic chemicalsQ43502943
Urinary bisphenol A concentrations in pregnant womenQ44030879
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectorganoidQ11293125
human embryonic stem cellQ59626782
P304page(s)e0133238
P577publication date2015-01-01
P1433published inPLOS OneQ564954
P1476titleDirected Differentiation of Human Embryonic Stem Cells into Prostate Organoids In Vitro and its Perturbation by Low-Dose Bisphenol A Exposure
P478volume10

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cites work (P2860)
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Q42776923Isolation and functional interrogation of adult human prostate epithelial stem cells at single cell resolution.
Q37551448Organoid model shows effect of BPA on prostate development
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Q88184003Organoids: a better in vitro model
Q90322538Propagation of human prostate tissue from induced pluripotent stem cells
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Q36107523Stem Cells as Hormone Targets That Lead to Increased Cancer Susceptibility
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Q98205105The prostaglandin synthases, COX-2 and L-PGDS, mediate prostate hyperplasia induced by low-dose bisphenol A
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