| scholarly article | Q13442814 |
| P50 | author | Richard M Ransohoff | Q87833085 |
| P2093 | author name string | Bruce T Lamb | |
| Shanya Jiang | |||
| Guixiang Xu | |||
| Olga N Kokiko-Cochran | |||
| Kiran Bhaskar | |||
| Astrid Cardona | |||
| Nicole Maphis | |||
| P2860 | cites work | What is the Most Sensitive Measure of Water Maze Probe Test Performance? | Q21129088 |
| The spectrum of disease in chronic traumatic encephalopathy | Q22242925 | ||
| TREM2 Variants in Alzheimer's Disease | Q22250873 | ||
| Variant of TREM2 Associated with the Risk of Alzheimer's Disease | Q22250874 | ||
| A protein kinase involved in the regulation of inflammatory cytokine biosynthesis | Q24311139 | ||
| Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways | Q26830542 | ||
| Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model | Q28115206 | ||
| Control of microglial neurotoxicity by the fractalkine receptor | Q28513748 | ||
| Interleukin-1 mediates pathological effects of microglia on tau phosphorylation and on synaptophysin synthesis in cortical neurons through a p38-MAPK pathway | Q28571359 | ||
| Trans-synaptic spread of tau pathology in vivo | Q28732288 | ||
| Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease | Q28943325 | ||
| Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Q29614879 | ||
| Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease | Q29614881 | ||
| Developments of a water-maze procedure for studying spatial learning in the rat | Q29617561 | ||
| Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion | Q29618089 | ||
| Neurodegenerative tauopathies | Q29619895 | ||
| CX3CR1 deficiency leads to impairment of hippocampal cognitive function and synaptic plasticity | Q30467724 | ||
| Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities | Q30500257 | ||
| Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice | Q30527791 | ||
| Microglial activation in brain lesions with tau deposits: comparison of human tauopathies and tau transgenic mice TgTauP301L. | Q33331809 | ||
| The inflammasomes. | Q33521252 | ||
| A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis | Q33720044 | ||
| Blocking IL-1 signaling rescues cognition, attenuates tau pathology, and restores neuronal β-catenin pathway function in an Alzheimer's disease model | Q33810933 | ||
| The myeloid cells of the central nervous system parenchyma | Q34024675 | ||
| Demonstration of Amyloid Deposits and Neurofibrillary Changes in Whole Brain Sections | Q48764154 | ||
| Severity of spatial learning impairment in aging: development of a learning index for performance in the Morris water maze | Q49154769 | ||
| Role of CX3CR1 (fractalkine receptor) in brain damage and inflammation induced by focal cerebral ischemia in mouse | Q49160789 | ||
| Characterization of the Drosophila melanogaster genome at the nuclear lamina. | Q52670843 | ||
| Genetic polymorphism of interleukin 1β -511C/T and susceptibility to sporadic Alzheimer's disease: a meta-analysis. | Q53108080 | ||
| Gene expression profiling in fetal, aged, and Alzheimer hippocampus: a continuum of stress-related signaling. | Q53262159 | ||
| Association of interleukin 1β polymorphisms and haplotypes with Alzheimer's disease. | Q53327868 | ||
| Kinase activities increase during the development of tauopathy in htau mice. | Q53561009 | ||
| Inhibitors of p38 mitogen-activated protein kinase enhance proliferation of mouse neural stem cells | Q80866679 | ||
| Regulation of Tau Pathology by the Microglial Fractalkine Receptor | Q34179654 | ||
| Microglia in neurodegeneration: molecular aspects | Q34349294 | ||
| Inflammation, autotoxicity and Alzheimer disease | Q34469472 | ||
| p38 MAPK in development and cancer | Q34515854 | ||
| New insights into the mechanism of IL-1beta maturation | Q35031950 | ||
| CX3CR1 protein signaling modulates microglial activation and protects against plaque-independent cognitive deficits in a mouse model of Alzheimer disease. | Q35213298 | ||
| CX(3)CR1 deficiency alters hippocampal-dependent plasticity phenomena blunting the effects of enriched environment | Q35404472 | ||
| Cognitive impairment following closed head injury | Q35529302 | ||
| Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation | Q35546446 | ||
| Exosome-associated tau is secreted in tauopathy models and is selectively phosphorylated in cerebrospinal fluid in early Alzheimer disease | Q35763138 | ||
| The many faces of tau | Q35870359 | ||
| Mechanisms of cell signaling and inflammation in Alzheimer's disease | Q36107658 | ||
| NSAIDs and Alzheimer disease: epidemiological, animal model and clinical studies | Q36477257 | ||
| Aging in mouse and human systems: a comparative study | Q36520954 | ||
| Inflammation in Alzheimer disease: driving force, bystander or beneficial response? | Q36589042 | ||
| Sustained interleukin-1β overexpression exacerbates tau pathology despite reduced amyloid burden in an Alzheimer's mouse model | Q36799810 | ||
| Association between the interleukin-1beta polymorphisms and Alzheimer's disease: a systematic review and meta-analysis | Q37233761 | ||
| Interleukin-1 promotion of MAPK-p38 overexpression in experimental animals and in Alzheimer's disease: potential significance for tau protein phosphorylation | Q37324225 | ||
| Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events | Q37424545 | ||
| Neuron-glia crosstalk in health and disease: fractalkine and CX3CR1 take centre stage | Q37424844 | ||
| Current status of chemokines in the adult CNS. | Q38085956 | ||
| Accumulation of filamentous tau in the cerebral cortex of human tau R406W transgenic mice | Q38585196 | ||
| Induction of inflammatory mediators and microglial activation in mice transgenic for mutant human P301S tau protein | Q38783280 | ||
| Propagation of tau misfolding from the outside to the inside of a cell. | Q39873721 | ||
| Microglia exhibit clonal variability in eliciting cytotoxic T lymphocyte responses independent of class I expression. | Q40909748 | ||
| Arthritis and anti-inflammatory agents as possible protective factors for Alzheimer's disease: a review of 17 epidemiologic studies | Q41075378 | ||
| In vivo imaging of microglial activation with [11C](R)-PK11195 PET in corticobasal degeneration | Q42468187 | ||
| Age-associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats | Q42482755 | ||
| In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy | Q42482808 | ||
| Microglial activation parallels system degeneration in progressive supranuclear palsy and corticobasal degeneration | Q42505583 | ||
| Tick-borne encephalitis carries a high risk of incomplete recovery in children | Q43926556 | ||
| High-yield isolation of murine microglia by mild trypsinization. | Q44645887 | ||
| Inflammation occurs early during the Abeta deposition process in TgCRND8 mice | Q44948592 | ||
| Lipopolysaccharide-induced inflammation exacerbates tau pathology by a cyclin-dependent kinase 5-mediated pathway in a transgenic model of Alzheimer's disease. | Q46303283 | ||
| Cell-cycle reentry and cell death in transgenic mice expressing nonmutant human tau isoforms. | Q46522758 | ||
| Effect of proinflammatory gene polymorphisms on the risk of Alzheimer's disease | Q46787216 | ||
| Interleukin-1 receptor antagonist penetrates human brain at experimentally therapeutic concentrations | Q47573293 | ||
| Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms | Q48254354 | ||
| Expression of inflammatory genes in the primary visual cortex of late-stage Alzheimer's disease | Q48272238 | ||
| Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and pro-inflammatory signaling | Q48463246 | ||
| Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy | Q48734532 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | Pt 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | brain | Q1073 |
| pathology | Q7208 | ||
| microglia | Q1622829 | ||
| P304 | page(s) | 1738-1755 | |
| P577 | publication date | 2015-03-31 | |
| P1433 | published in | Brain | Q897386 |
| P1476 | title | Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain | |
| P478 | volume | 138 |
| Q27334236 | 3D Visualization of the Temporal and Spatial Spread of Tau Pathology Reveals Extensive Sites of Tau Accumulation Associated with Neuronal Loss and Recognition Memory Deficit in Aged Tau Transgenic Mice |
| Q57927766 | A Closer Look into the Role of Protein Tau in the Identification of Promising Therapeutic Targets for Alzheimer's Disease |
| Q90932824 | A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy |
| Q64245708 | A walk through tau therapeutic strategies |
| Q58611582 | APOE at the interface of inflammation, neurodegeneration and pathological protein spread in Alzheimer's disease |
| Q38623440 | Absence of CX3CR1 impairs the internalization of Tau by microglia. |
| Q89624658 | Absence of microglia or presence of peripherally-derived macrophages does not affect tau pathology in young or old hTau mice |
| Q90076026 | Acid Sphingomyelinase Inhibition Mitigates Histopathologic and Behavioral Changes in a Murine Model of Traumatic Brain Injury |
| Q64273642 | Aggregated Tau activates NLRP3-ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo |
| Q55353865 | Alzheimer's Disease and Type 2 Diabetes: A Critical Assessment of the Shared Pathological Traits. |
| Q30387426 | Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury |
| Q89486165 | Amyloid Fibril-Induced Astrocytic Glutamate Transporter Disruption Contributes to Complement C1q-Mediated Microglial Pruning of Glutamatergic Synapses |
| Q46240783 | Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies. |
| Q91526804 | Amyloid-β-independent regulators of tau pathology in Alzheimer disease |
| Q90104103 | Applications of amyloid, tau, and neuroinflammation PET imaging to Alzheimer's disease and mild cognitive impairment |
| Q48361868 | Association of the CX3CR1-V249I Variant with Neurofibrillary Pathology Progression in Late-Onset Alzheimer's Disease |
| Q89791301 | Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E ε4 genotype |
| Q91529261 | BIN1 favors the spreading of Tau via extracellular vesicles |
| Q30141537 | Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer’s disease |
| Q59349485 | CNS-Wide over Expression of Fractalkine Improves Cognitive Functioning in a Tauopathy Model |
| Q94092672 | CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice |
| Q26739374 | CX3CL1/CX3CR1 in Alzheimer's Disease: A Target for Neuroprotection |
| Q36346809 | Ccr2 deletion dissociates cavity size and tau pathology after mild traumatic brain injury |
| Q50034510 | Cerebrospinal Fluid and Plasma Levels of Inflammation Differentially Relate to CNS Markers of Alzheimer's Disease Pathology and Neuronal Damage |
| Q47905080 | Changes in neocortical and hippocampal microglial cells during hibernation. |
| Q57464033 | Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice |
| Q55505826 | Chronic stress as a risk factor for Alzheimer's disease: Roles of microglia-mediated synaptic remodeling, inflammation, and oxidative stress. |
| Q47887763 | Chronic traumatic encephalopathy-integration of canonical traumatic brain injury secondary injury mechanisms with tau pathology |
| Q57029721 | Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease |
| Q90597056 | Dementia with Lewy bodies - from scientific knowledge to clinical insights |
| Q40240888 | Direct Evidence of Internalization of Tau by Microglia In Vitro and In Vivo. |
| Q92209301 | Dissemination of brain inflammation in traumatic brain injury |
| Q59328931 | Distinct Microglial Responses in Two Transgenic Murine Models of TAU Pathology |
| Q58716431 | Divergent brain gene expression patterns associate with distinct cell-specific tau neuropathology traits in progressive supranuclear palsy |
| Q39217121 | Dynamics of the Complement, Cytokine, and Chemokine Systems in the Regulation of Synaptic Function and Dysfunction Relevant to Alzheimer's Disease |
| Q38875190 | Dysfunctional Sensory Modalities, Locus Coeruleus, and Basal Forebrain: Early Determinants that Promote Neuropathogenesis of Cognitive and Memory Decline and Alzheimer's Disease |
| Q98464883 | Emerging Promise of Cannabinoids for the Management of Pain and Associated Neuropathological Alterations in Alzheimer's Disease |
| Q90454180 | Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer's Disease |
| Q92529636 | Endolysosome and Autolysosome Dysfunction in Alzheimer's Disease: Where Intracellular and Extracellular Meet |
| Q37525481 | Evidence of Tau Hyperphosphorylation and Dystrophic Microglia in the Common Marmoset |
| Q89497605 | Exposure to 3-Nitropropionic Acid Mitochondrial Toxin Induces Tau Pathology in Tangle-Mouse Model and in Wild Type-Mice |
| Q64074494 | Extracellular Monomeric Tau Is Internalized by Astrocytes |
| Q91635608 | Functional connectivity associated with tau levels in ageing, Alzheimer's, and small vessel disease |
| Q26748713 | Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease |
| Q26747585 | Fundamental role of pan-inflammation and oxidative-nitrosative pathways in neuropathogenesis of Alzheimer's disease in focal cerebral ischemic rats |
| Q92535576 | Genetic Background Influences the Propagation of Tau Pathology in Transgenic Rodent Models of Tauopathy |
| Q104504605 | Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study |
| Q58699436 | Genetically enhancing the expression of chemokine domain of CXCL1 fails to prevent tau pathology in mouse models of tauopathy |
| Q60044492 | Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model |
| Q26765365 | Glial Tau Pathology in Tauopathies: Functional Consequences |
| Q32173558 | Glial contributions to neurodegeneration in tauopathies |
| Q36810157 | High Resolution Dissection of Reactive Glial Nets in Alzheimer's Disease |
| Q35986968 | Humanized Tau Mice with Regionalized Amyloid Exhibit Behavioral Deficits but No Pathological Interaction |
| Q47983749 | Hyperthermia and Mild Traumatic Brain Injury: Effects on Inflammation and the Cerebral Vasculature |
| Q47218394 | Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies |
| Q54974138 | Impact of the biological definition of Alzheimer's disease using amyloid, tau and neurodegeneration (ATN): what about the role of vascular changes, inflammation, Lewy body pathology? |
| Q90399853 | In vivo Bioluminescence Imaging Used to Monitor Disease Activity and Therapeutic Response in a Mouse Model of Tauopathy |
| Q38891157 | Inflammation in Alzheimer's disease: Lessons learned from microglia-depletion models |
| Q58700943 | Inflammation: the link between comorbidities, genetics, and Alzheimer's disease |
| Q55289589 | Innate immune activation in Alzheimer’s disease. |
| Q57039694 | Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau |
| Q91114669 | Interplay between innate immunity and Alzheimer disease: APOE and TREM2 in the spotlight |
| Q91660737 | Intersection of pathological tau and microglia at the synapse |
| Q90679397 | Is Alzheimer disease a failure of mobilizing immune defense? Lessons from cognitively fit oldest-old |
| Q41159842 | Lessons Learned about Neurodegeneration from Microglia and Monocyte Depletion Studies |
| Q58726435 | Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia |
| Q47926820 | Macrophage Migration Inhibitory Factor is Associated with Biomarkers of Alzheimer's Disease Pathology and Predicts Cognitive Decline in Mild Cognitive Impairment and Mild Dementia. |
| Q46461757 | Microglia and macrophages in brain homeostasis and disease |
| Q90705375 | Microglia changes associated to Alzheimer's disease pathology in aged chimpanzees |
| Q55073016 | Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative. |
| Q56922819 | Microglia in Alzheimer's disease |
| Q60949648 | Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response |
| Q37374408 | Microglial neuroinflammation contributes to tau accumulation in chronic traumatic encephalopathy. |
| Q48113339 | Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift |
| Q64073405 | Neuroinflammation and Perioperative Neurocognitive Disorders |
| Q64237341 | Neuroinflammation and fractalkine signaling in Alzheimer's disease |
| Q90399950 | Neuroinflammation as a Common Feature of Neurodegenerative Disorders |
| Q26771536 | Neuroinflammation in Multiple System Atrophy: Response to and Cause of α-Synuclein Aggregation |
| Q64933464 | Neuroinflammation in mouse models of Alzheimer's disease. |
| Q55304161 | Neuroinflammation is increased in the parietal cortex of atypical Alzheimer's disease. |
| Q91583342 | Neurons Expressing Pathological Tau Protein Trigger Dramatic Changes in Microglial Morphology and Dynamics |
| Q98190790 | Obesity impacts brain metabolism and structure independently of amyloid and tau pathology in healthy elderly |
| Q39030129 | Opposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network |
| Q26776178 | PET Imaging of Epigenetic Influences on Alzheimer's Disease |
| Q58566486 | Partial reduction of microglia does not affect tau pathology in aged mice |
| Q47135235 | Practical considerations for choosing a mouse model of Alzheimer's disease |
| Q92972077 | Qß Virus-like particle-based vaccine induces robust immunity and protects against tauopathy |
| Q49646689 | RIPK1 promotes inflammation and β-amyloid accumulation in Alzheimer's disease |
| Q48127231 | Reduced gliotransmitter release from astrocytes mediates tau-induced synaptic dysfunction in cultured hippocampal neurons. |
| Q93197465 | Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy |
| Q99585601 | Restoring regulatory T-cell dysfunction in Alzheimer's disease through ex vivo expansion |
| Q64913586 | Rev-erbs and Glia-Implications for Neurodegenerative Diseases. |
| Q58606221 | Role of the Fractalkine Receptor in CNS Autoimmune Inflammation: New Approach Utilizing a Mouse Model Expressing the Human CX3CR1 Variant |
| Q58780923 | Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies |
| Q54255866 | SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy. |
| Q37504904 | Selective suppression of the α isoform of p38 MAPK rescues late-stage tau pathology. |
| Q37410147 | Soluble phospho-tau from Alzheimer's disease hippocampus drives microglial degeneration |
| Q41052224 | Spread of tau down neural circuits precedes synapse and neuronal loss in the rTgTauEC mouse model of early Alzheimer's disease |
| Q48524916 | Stimulation of TLR4 Attenuates Alzheimer's Disease-Related Symptoms and Pathology in Tau-Transgenic Mice |
| Q98303367 | Synergy between amyloid-β and tau in Alzheimer's disease |
| Q42690758 | TREM2 deficiency exacerbates tau pathology through dysregulated kinase signaling in a mouse model of tauopathy |
| Q48419551 | Targeting CCR3 to Reduce Amyloid-β Production, Tau Hyperphosphorylation, and Synaptic Loss in a Mouse Model of Alzheimer's Disease |
| Q26744219 | Targeting innate immunity for neurodegenerative disorders of the central nervous system |
| Q53376999 | Targeting microglia for the treatment of Alzheimer's Disease. |
| Q47233523 | Tau Proteins and Tauopathies in Alzheimer's Disease |
| Q39243339 | Tau Spread, Apolipoprotein E, Inflammation, and More: Rapidly Evolving Basic Science in Alzheimer Disease |
| Q52315334 | Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies? |
| Q64098797 | Tau as a mediator of neurotoxicity associated to cerebral amyloid angiopathy |
| Q100431722 | Tau at the interface between neurodegeneration and neuroinflammation |
| Q30667424 | Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model |
| Q38657468 | Tau in physiology and pathology |
| Q28070250 | Tau physiology and pathomechanisms in frontotemporal lobar degeneration |
| Q47689697 | Tau-based therapies in neurodegeneration: opportunities and challenges |
| Q47253592 | Tauopathies: Mechanisms and Therapeutic Strategies |
| Q39149587 | The Role of Microglia in the Etiology and Evolution of Chronic Traumatic Encephalopathy. |
| Q90454167 | The Role of Microglia in the Spread of Tau: Relevance for Tauopathies |
| Q26750987 | The dual roles of cytokines in Alzheimer's disease: update on interleukins, TNF-α, TGF-β and IFN-γ |
| Q94585854 | The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study |
| Q58725042 | The role of microglia in processing and spreading of bioactive tau seeds in Alzheimer's disease |
| Q42656274 | The roles of inflammation and immune mechanisms in Alzheimer's disease |
| Q47161099 | Tissue magnetic susceptibility mapping as a marker of tau pathology in Alzheimer's disease |
| Q38599516 | Traumatic brain injury in hTau model mice: Enhanced acute macrophage response and altered long-term recovery. |
| Q37707241 | Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology. |
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