ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores

scientific article

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.201408089
P8608Fatcat IDrelease_d2qu3bugdrgihhxwin47oahpoi
P932PMC publication ID4792069
P698PubMed publication ID26953350

P50authorJan EllenbergQ1296661
Robert MahenQ56065753
Bianca NijmeijerQ57212053
Jean-Karim HérichéQ34388112
Tomoya S. KitajimaQ37377144
Thomas WalterQ43086580
P2093author name stringStefano Maffini
Jan-Michael Peters
Kota Miura
Mayumi Isokane
Miroslav Penchev Ivanov
P2860cites workmph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombeQ48037929
CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signalingQ52660937
Evidence that Aurora B is implicated in spindle checkpoint signalling independently of error correctionQ24297396
Re-evaluating the role of Tao1 in the spindle checkpointQ24299702
A mammalian Rho-specific guanine-nucleotide exchange factor (p164-RhoGEF) without a pleckstrin homology domainQ24299945
Mps1 phosphorylates Borealin to control Aurora B activity and chromosome alignmentQ24310028
Human Mps1 kinase is required for the spindle assembly checkpoint but not for centrosome duplicationQ24536263
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpointQ24675117
The spindle assembly checkpointQ27023697
Chromosomal instability by inefficient Mps1 auto-activation due to a weakened mitotic checkpoint and lagging chromosomesQ27301063
A TPR domain–containing N-terminal module of MPS1 is required for its kinetochore localization by Aurora BQ27677259
The spindle-assembly checkpoint in space and timeQ27860766
Fiji: an open-source platform for biological-image analysisQ27860912
Quantification of cytosolic interactions identifies Ede1 oligomers as key organizers of endocytosisQ27930149
Spatial regulation of Fus3 MAP kinase activity through a reaction-diffusion mechanism in yeast pheromone signalling.Q27932098
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption.Q27933791
The Saccharomyces cerevisiae spindle pole body duplication gene MPS1 is part of a mitotic checkpointQ27939738
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2Q28204299
Dbl family guanine nucleotide exchange factorsQ28209857
Timing and checkpoints in the regulation of mitotic progressionQ28270657
Emi1 regulates the anaphase-promoting complex by a different mechanism than Mad2 proteinsQ28343954
Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genesQ29615188
On the road to cancer: aneuploidy and the mitotic checkpointQ29619455
Aurora B phosphorylates centromeric MCAK and regulates its localization and microtubule depolymerization activityQ30312108
Nuclear import and assembly of influenza A virus RNA polymerase studied in live cells by fluorescence cross-correlation spectroscopy.Q30382441
Sustained Mps1 activity is required in mitosis to recruit O-Mad2 to the Mad1-C-Mad2 core complexQ30477599
BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammalsQ33327076
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversineQ34026669
Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling.Q34026709
Profiling the Trypanosoma cruzi phosphoproteome.Q34038289
CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.Q34130316
A bioinformatics method identifies prominent off-targeted transcripts in RNAi screensQ34161428
Spindle checkpoint protein dynamics at kinetochores in living cells.Q34325192
Determining protease activity in vivo by fluorescence cross-correlation analysisQ34351541
Re-examination of siRNA specificity questions role of PICH and Tao1 in the spindle checkpoint and identifies Mad2 as a sensitive target for small RNAsQ35012285
Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindleQ36234928
Autophosphorylation-dependent activation of human Mps1 is required for the spindle checkpointQ36299859
Phosphorylation of microtubule-binding protein Hec1 by mitotic kinase Aurora B specifies spindle checkpoint kinase Mps1 signaling at the kinetochore.Q37388868
A chemical tool box defines mitotic and interphase roles for Mps1 kinase.Q37772019
Spindle assembly checkpoint: the third decadeQ37956287
Microtubule attachment and spindle assembly checkpoint signalling at the kinetochoreQ38069082
The vertebrate cell kinetochore and its roles during mitosisQ38717231
Mps1 kinase activity restrains anaphase during an unperturbed mitosis and targets Mad2 to kinetochores.Q39131699
Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis.Q39540799
Work flow for multiplexing siRNA assays by solid-phase reverse transfection in multiwell platesQ39965401
Feature point tracking and trajectory analysis for video imaging in cell biology.Q40393446
High-throughput fluorescence correlation spectroscopy enables analysis of proteome dynamics in living cellsQ41212579
Correcting for spectral cross-talk in dual-color fluorescence cross-correlation spectroscopyQ41247436
MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC componentsQ42152374
Constitutive Mad1 targeting to kinetochores uncouples checkpoint signalling from chromosome biorientationQ42167079
Release of Mps1 from kinetochores is crucial for timely anaphase onset.Q42407469
Sister chromatid separation and chromosome re-duplication are regulated by different mechanisms in response to spindle damageQ42673791
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.Q43680754
Automatic identification and clustering of chromosome phenotypes in a genome wide RNAi screen by time-lapse imagingQ44264854
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
kinetochoreQ908912
P304page(s)647-659
P577publication date2016-03-07
P1433published inJournal of Cell BiologyQ1524550
P1476titleARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores
P478volume212

Reverse relations

cites work (P2860)
Q39006774ARHGEF17 sets the timer for retention of Mps1 at kinetochores
Q59081843Experimental and computational framework for a dynamic protein atlas of human cell division.
Q57173343Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis
Q39258525Playing polo during mitosis: PLK1 takes the lead.
Q41459053Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis.
Q64058303Recent Progress on the Localization of the Spindle Assembly Checkpoint Machinery to Kinetochores
Q92798444TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination

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