Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound

scientific article

Noninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2013PLoSO...857682H
P356DOI10.1371/JOURNAL.PONE.0057682
P932PMC publication ID3584045
P698PubMed publication ID23460893
P5875ResearchGate publication ID235788097

P50authorJin-Chung ChenQ41843136
Ya-Tin LinQ59693441
Hao-Li LiuQ87680631
P2093author name stringChao-Lin Liu
Chia-Rui Shen
Tzu-Chen Yen
Chih-Jen Wen
Kuo-Chen Wei
Chiung-Yin Huang
Po-Hung Hsu
P2860cites workMembrane-associated heparan sulfate proteoglycan is a receptor for adeno-associated virus type 2 virionsQ24531466
Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonicationsQ28297458
AAV2-GAD gene therapy for advanced Parkinson's disease: a double-blind, sham-surgery controlled, randomised trialQ28307713
Targeted delivery of self-complementary adeno-associated virus serotype 9 to the brain, using magnetic resonance imaging-guided focused ultrasoundQ30447740
Novel magnetic/ultrasound focusing system enhances nanoparticle drug delivery for glioma treatmentQ30474002
Transcranial magnetic resonance imaging- guided focused ultrasound surgery of brain tumors: initial findings in 3 patientsQ30477383
Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brainQ30479578
Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruptionQ30500905
Adeno-associated virus serotypes: vector toolkit for human gene therapyQ33249130
Efficient gene delivery and selective transduction of glial cells in the mammalian brain by AAV serotypes isolated from nonhuman primates.Q33713108
Intravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neuronsQ33713769
Safety and tolerability of putaminal AADC gene therapy for Parkinson diseaseQ33731687
Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbitsQ33954300
Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasoundQ33992793
Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasoundQ34003611
Controlling brain tumor growth by intraventricular administration of an AAV vector encoding IFN-betaQ34158558
RH10 provides superior transgene expression in mice when compared with natural AAV serotypes for neonatal gene therapyQ34166253
Adeno-associated virus 2-mediated gene transfer in vivo: organ-tropism and expression of transduced sequences in miceQ34429058
Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug deliveryQ34564681
Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trialQ34640765
Treatment of late infantile neuronal ceroid lipofuscinosis by CNS administration of a serotype 2 adeno-associated virus expressing CLN2 cDNA.Q34778098
Preclinical differences of intravascular AAV9 delivery to neurons and glia: a comparative study of adult mice and nonhuman primatesQ35086714
Recombinant adeno-associated virus type 2, 4, and 5 vectors: transduction of variant cell types and regions in the mammalian central nervous system.Q35111738
Promoters and serotypes: targeting of adeno-associated virus vectors for gene transfer in the rat central nervous system in vitro and in vivoQ35948485
Pseudotyped adeno-associated virus 2/9-delivered CCL11 shRNA alleviates lung inflammation in an allergen-sensitized mouse modelQ36401352
Stable transgene expression in rod photoreceptors after recombinant adeno-associated virus-mediated gene transfer to monkey retinaQ36439639
Tropism and toxicity of adeno-associated viral vector serotypes 1, 2, 5, 6, 7, 8, and 9 in rat neurons and glia in vitro.Q36541150
Specific AAV serotypes stably transduce primary hippocampal and cortical cultures with high efficiency and low toxicityQ36631977
Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challengesQ37866086
Quantifying transduction efficiencies of unmodified and tyrosine capsid mutant AAV vectors in vitro using two ocular cell linesQ39546264
Tau expression levels from various adeno-associated virus vector serotypes produce graded neurodegenerative disease statesQ39996419
Safety study and characterization of E1A-liposome complex gene-delivery protocol in an ovarian cancer modelQ40825865
Convection-enhanced delivery of AAV vector in parkinsonian monkeys; in vivo detection of gene expression and restoration of dopaminergic function using pro-drug approachQ40870377
Gene transfer and expression in oligodendrocytes under the control of myelin basic protein transcriptional control region mediated by adeno-associated virusQ41052074
Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brainQ41333437
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Inhibition of acidic mammalian chitinase by RNA interference suppresses ovalbumin-sensitized allergic asthmaQ42797865
Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatmentQ43088262
Immediate and long-term safety of recombinant adeno-associated virus injection into the nonhuman primate muscleQ44474527
Self-complementary adeno-associated virus serotype 2 vector: global distribution and broad dispersion of AAV-mediated transgene expression in mouse brainQ44686125
Recombinant AAV viral vectors pseudotyped with viral capsids from serotypes 1, 2, and 5 display differential efficiency and cell tropism after delivery to different regions of the central nervous systemQ45007196
CERE-110, an adeno-associated virus-based gene delivery vector expressing human nerve growth factor for the treatment of Alzheimer's disease.Q45376997
Kinetics of transgene expression in mouse retina following sub-retinal injection of recombinant adeno-associated virusQ45712572
Oligodendrocyte-specific gene expression in mouse brain: use of a myelin-forming cell type-specific promoter in an adeno-associated virusQ45743733
Differential and persistent expression patterns of CNS gene transfer by an adeno-associated virus (AAV) vectorQ45769447
Hemorrhage detection during focused-ultrasound induced blood-brain-barrier opening by using susceptibility-weighted magnetic resonance imaging.Q47875953
Immune responses to AAV in a phase I study for Canavan diseaseQ48620414
Targeted gene delivery to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruptionQ50245668
Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubblesQ50250294
Gene expression from recombinant viral vectors in the central nervous system after blood-brain barrier disruption.Q50761827
Safety and Efficacy of Regional Intravenous (RI) Versus Intramuscular (IM) Delivery of rAAV1 and rAAV8 to Nonhuman Primate Skeletal Muscle.Q54457954
Heparan sulphate proteoglycans in glia and in the normal and injured CNS: expression of sulphotransferases and changes in sulphationQ54888139
Transduction of murine cerebellar neurons with recombinant FIV and AAV5 vectorsQ74285552
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectbrainQ1073
microbubbleQ6839290
focused ultrasoundQ50333304
P304page(s)e57682
P577publication date2013-02-27
P1433published inPLOS OneQ564954
P1476titleNoninvasive and targeted gene delivery into the brain using microbubble-facilitated focused ultrasound
P478volume8

Reverse relations

cites work (P2860)
Q30448815A novel cationic microbubble coated with stearic acid-modified polyethylenimine to enhance DNA loading and gene delivery by ultrasound
Q30368351Acoustic cavitation-based monitoring of the reversibility and permeability of ultrasound-induced blood-brain barrier opening
Q59968531Acoustically targeted chemogenetics for the non-invasive control of neural circuits
Q51185898Antibody-coated nanoparticles are promising molecular probes for microscopic analysis of cell behavior.
Q58600222Applications of Focused Ultrasound in Cerebrovascular Diseases and Brain Tumors
Q93017847Applications of Ultrasound to Stimulate Therapeutic Revascularization
Q39013294Crossing the Blood-Brain Barrier: Recent Advances in Drug Delivery to the Brain
Q28080611Drug and gene delivery across the blood-brain barrier with focused ultrasound
Q30414698Drug delivery across the blood-brain barrier using focused ultrasound
Q30387126Enhanced delivery and bioactivity of the neurturin neurotrophic factor through focused ultrasound-mediated blood--brain barrier opening in vivo.
Q28082016Evolving Drug Delivery Strategies to Overcome the Blood Brain Barrier.
Q30394357Focused ultrasound-mediated drug delivery through the blood-brain barrier
Q38306886Gene delivery in tissue engineering and regenerative medicine.
Q57020987In vivo methods for acute modulation of gene expression in the central nervous system
Q97599625Innovations in the Neurosurgical Management of Epilepsy
Q104516383Innovative Applications of MR-Guided Focused Ultrasound for Neurological Disorders
Q30434125Investigation of temporal vascular effects induced by focused ultrasound treatment with speckle-variance optical coherence tomography
Q88467192Low-intensity ultrasound promotes the horizontal transfer of resistance genes mediated by plasmids in E. coli
Q28817563MR-Guided Delivery of Hydrophilic Molecular Imaging Agents Across the Blood-Brain Barrier Through Focused Ultrasound
Q90210921MRI Monitoring and Quantification of Ultrasound-Mediated Delivery of Liposomes Dually Labeled with Gadolinium and Fluorophore through the Blood-Brain Barrier
Q91733486MRI-Guided Focused Ultrasound for Targeted Delivery of rAAV to the Brain
Q60923907Magnetic Resonance-Guided Focused Ultrasound : Current Status and Future Perspectives in Thermal Ablation and Blood-Brain Barrier Opening
Q30367059Microbubble gas volume: A unifying dose parameter in blood-brain barrier opening by focused ultrasound
Q38612543Microbubble-Assisted Ultrasound for Drug Delivery in the Brain and Central Nervous System
Q30435931Microbubble-mediated ultrasound enhances the lethal effect of gentamicin on planktonic Escherichia coli
Q58572994Modulation of Brain Function and Behavior by Focused Ultrasound
Q27026978Nanoscale drug delivery systems and the blood-brain barrier
Q30374364Neural immune modulation and immunotherapy assisted by focused ultrasound induced blood-brain barrier opening
Q100415690Non-invasive molecularly-specific millimeter-resolution manipulation of brain circuits by ultrasound-mediated aggregation and uncaging of drug carriers
Q31048620Noninvasive and targeted delivery of therapeutics to the brain using focused ultrasound
Q27301281Noninvasive, Targeted, and Non-Viral Ultrasound-Mediated GDNF-Plasmid Delivery for Treatment of Parkinson's Disease.
Q30394725Noninvasive, neuron-specific gene therapy can be facilitated by focused ultrasound and recombinant adeno-associated virus
Q28080896Optogenetic tools for modulating and probing the epileptic network
Q58796703State-of-the-art of microbubble-assisted blood-brain barrier disruption
Q31114235Stereotactic modulation of blood-brain barrier permeability to enhance drug delivery
Q30407897The size of blood-brain barrier opening induced by focused ultrasound is dictated by the acoustic pressure
Q64241244Theranostic Strategy of Focused Ultrasound Induced Blood-Brain Barrier Opening for CNS Disease Treatment
Q52568379Ultrasound-Triggered Effects of the Microbubbles Coupled to GDNF Plasmid-Loaded PEGylated Liposomes in a Rat Model of Parkinson's Disease.
Q28539271Ultrasound-mediated blood-brain barrier disruption for targeted drug delivery in the central nervous system

Search more.