Fusion of protein aggregates facilitates asymmetric damage segregation

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Fusion of protein aggregates facilitates asymmetric damage segregation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.1001886
P932PMC publication ID4061010
P698PubMed publication ID24936793
P5875ResearchGate publication ID263198644

P50authorIva TolićQ21402740
Steven J. LadeQ41049057
P2093author name stringSimon Alberti
Thilo Gross
Miguel Coelho
P2860cites workLocalization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effectQ21563476
Hsp42 is required for sequestration of protein aggregates into deposition sites in Saccharomyces cerevisiaeQ24610346
Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogasterQ24627262
Collapse of proteostasis represents an early molecular event in Caenorhabditis elegans agingQ24643933
Misfolded proteins partition between two distinct quality control compartmentsQ24651093
Nucleocytoplasmic trafficking of the molecular chaperone Hsp104 in unstressed and heat-shocked cellsQ50659260
Confinement to organelle-associated inclusion structures mediates asymmetric inheritance of aggregated protein in budding yeastQ50782681
A super-assembly of Whi3 encodes memory of deceptive encounters by single cells during yeast courtship.Q50869451
The polarisome is required for segregation and retrograde transport of protein aggregates.Q53343132
Highly inclined thin illumination enables clear single-molecule imaging in cells.Q53442959
Segregation of protein aggregates involves actin and the polarity machineryQ82684962
A systematic survey identifies prions and illuminates sequence features of prionogenic proteinsQ24658451
Polarised asymmetric inheritance of accumulated protein damage in higher eukaryotesQ27334980
Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregatesQ27929853
Hsp104, Hsp70, and Hsp40: a novel chaperone system that rescues previously aggregated proteinsQ27931364
Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation.Q27933749
Protein disaggregation mediated by heat-shock protein Hsp104.Q27940314
Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal deathQ28287762
Aggresomes: a cellular response to misfolded proteinsQ28292275
Heterologous modules for efficient and versatile PCR-based gene targeting in Schizosaccharomyces pombeQ29547755
Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation.Q30481495
Quantitative and spatio-temporal features of protein aggregation in Escherichia coli and consequences on protein quality control and cellular ageingQ30493630
Protein aggregation behavior regulates cyclin transcript localization and cell-cycle controlQ30585049
Spatial sequestration of misfolded proteins by a dynamic chaperone pathway enhances cellular fitness during stressQ30585884
Asymmetric inheritance of oxidatively damaged proteins during cytokinesisQ34180285
Fission yeast does not age under favorable conditions, but does so after stress.Q34371090
Aging may be a conditional strategic choice and not an inevitable outcome for bacteriaQ34568843
FM-dyes as experimental probes for dissecting vesicle trafficking in living plant cellsQ35752966
On the evolutionary origin of agingQ36103426
Some like it hot: the structure and function of small heat-shock proteins.Q36277178
Compartmentalization of superoxide dismutase 1 (SOD1G93A) aggregates determines their toxicityQ36300695
Basic methods for fission yeastQ36405219
Selective benefits of damage partitioning in unicellular systems and its effects on agingQ36999962
A diversity of assembly mechanisms of a generic amyloid foldQ37897372
Tracking protein aggregation and mislocalization in cells with flow cytometryQ39377946
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functionsQ39610788
Global transcriptional responses of fission yeast to environmental stressQ39697098
Fission yeast Pom1p kinase activity is cell cycle regulated and essential for cellular symmetry during growth and divisionQ39714813
Motility and segregation of Hsp104-associated protein aggregates in budding yeast.Q39775402
The yeast AAA+ chaperone Hsp104 is part of a network that links the actin cytoskeleton with the inheritance of damaged proteinsQ41349152
Interaction of a small heat shock protein of the fission yeast, Schizosaccharomyces pombe, with a denatured protein at elevated temperature.Q46627905
Germline P granules are liquid droplets that localize by controlled dissolution/condensationQ47748097
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)e1001886
P577publication date2014-06-17
P1433published inPLOS BiologyQ1771695
P1476titleFusion of protein aggregates facilitates asymmetric damage segregation
P478volume12

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cites work (P2860)
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Q52943994Asymmetric damage segregation at cell division via protein aggregate fusion and attachment to organelles.
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Q63610180Growth‐driven displacement of protein aggregates along the cell length ensures partitioning to both daughter cells in Caulobacter crescentus
Q47322204IMiQ: a novel protein quality control compartment protecting mitochondrial functional integrity
Q42113553Imperfect asymmetry: The mechanism governing asymmetric partitioning of damaged cellular components during mitosis
Q42029053In silico analysis of division times of Escherichia coli populations as a function of the partitioning scheme of non-functional proteins
Q47323471Is Aggregate-Dependent Yeast Aging Fortuitous? A Model of Damage Segregation and Aggregate Dynamics
Q39853780Kinetics of Formation and Asymmetrical Distribution of Hsp104-Bound Protein Aggregates in Yeast
Q27318775Live cell interferometry quantifies dynamics of biomass partitioning during cytokinesis
Q90168460Microbial ageing and longevity
Q38999127Prions, Chaperones, and Proteostasis in Yeast
Q40348586Protein aggregates are associated with replicative aging without compromising protein quality control
Q58049566Protein aggregates encode epigenetic memory of stressful encounters in individual Escherichia coli cells
Q34520461Protein aggregation as a mechanism of adaptive cellular responses.
Q38963404Restricted access: spatial sequestration of damaged proteins during stress and aging.
Q39102253Role of sHsps in organizing cytosolic protein aggregation and disaggregation
Q41070069Spatial regulation of coalesced protein assemblies: Lessons from yeast to diseases.
Q47118931Stressed mycobacteria use the chaperone ClpB to sequester irreversibly oxidized proteins asymmetrically within and between cells
Q39199069The Upsides and Downsides of Organelle Interconnectivity
Q64067570The fitness cost and benefit of phase-separated protein deposits
Q101574053Vimentin protects differentiating stem cells from stress

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