Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7

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Innate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7 is …
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scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PPAT.1000813
P8608Fatcat IDrelease_tz6y2b7jcbcvxcqjkzip2speni
P3181OpenCitations bibliographic resource ID2616621
P932PMC publication ID2837405
P698PubMed publication ID20300600
P5875ResearchGate publication ID42346148

P50authorPaul M KayeQ59697523
Mattias SvenssonQ41598129
P2093author name stringRebecca Phillips
Asher Maroof
Lynette Beattie
Najmeeyah Brown
Naveed Aziz
Nathalie Signoret
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Interaction of SIGNR1 expressed by marginal zone macrophages with marginal zone B cells is essential to early IgM responses against Streptococcus pneumoniaeQ28592413
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NK cell activation in visceral leishmaniasis requires TLR9, myeloid DCs, and IL-12, but is independent of plasmacytoid DCs.Q36229299
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SIGN-R1 contributes to protection against lethal pneumococcal infection in mice.Q36399613
Mice deficient in nuclear factor (NF)-kappa B/p52 present with defects in humoral responses, germinal center reactions, and splenic microarchitectureQ36400143
New insights into the cell biology of the marginal zone of the spleenQ36544048
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Marginal zone macrophages express a murine homologue of DC-SIGN that captures blood-borne antigens in vivoQ63408277
Marginal metallophilic cells of the mouse spleen identified by a monoclonal antibodyQ69569968
Intracellular Leishmania amazonensis amastigotes internalize and degrade MHC class II molecules of their host cellsQ71825225
Leishmania donovani-infected macrophages: characterization of the parasitophorous vacuole and potential role of this organelle in antigen presentationQ72864200
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B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph nodeQ80688189
Essential involvement of CX3CR1-mediated signals in the bactericidal host defense during septic peritonitisQ81925259
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Transcriptional re-programming of primary macrophages reveals distinct apoptotic and anti-tumoral functions of IRF-3 and IRF-7.Q37411480
Localization of marginal zone macrophages is regulated by C-C chemokine ligands 21/19.Q38883156
An in vivo analysis of cytokine production during Leishmania donovani infection in scid mice.Q38994048
Dendritic cells, but not macrophages, produce IL-12 immediately following Leishmania donovani infectionQ39029010
Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.Q39495272
Subcapsular sinus macrophages in lymph nodes clear lymph-borne viruses and present them to antiviral B cellsQ40068378
Leishmania donovani affects antigen presentation of macrophage by disrupting lipid raftsQ40382223
Spatiotemporal regulation of MyD88-IRF-7 signalling for robust type-I interferon inductionQ40437839
Parasite-accessory cell interactions in murine leishmaniasis. II. Leishmania donovani suppresses macrophage expression of class I and class II major histocompatibility complex gene productsQ42487746
Cultured mouse marrow cell lines: interactions between fibroblastoid cells and monocytesQ42798754
Crucial role of marginal zone macrophages and marginal zone metallophils in the clearance of lymphocytic choriomeningitis virus infectionQ43530560
Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasiteQ44248030
Macrophages of the splenic marginal zone are essential for trapping of blood-borne particulate antigen but dispensable for induction of specific T cell responsesQ44521235
Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infectionQ44539906
Constitutive IFN-alpha/beta signal for efficient IFN-alpha/beta gene induction by virusQ45736557
Splenic marginal metallophilic macrophages and marginal zone macrophages are the major interferon-alpha/beta producers in mice upon intravenous challenge with herpes simplex virusQ45749828
Subcapsular encounter and complement-dependent transport of immune complexes by lymph node B cells.Q46017170
Cholesterol depletion associated with Leishmania major infection alters macrophage CD40 signalosome composition and effector function.Q46130895
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectmacrophageQ184204
Leishmania donovaniQ1950752
P304page(s)e1000813
P577publication date2010-03-01
P1433published inPLOS PathogensQ283209
P1476titleInnate killing of Leishmania donovani by macrophages of the splenic marginal zone requires IRF-7
P478volume6

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