Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint

scientific article (publication date: 2013)

Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PGEN.1003679
P932PMC publication ID3749324
P698PubMed publication ID23990794
P5875ResearchGate publication ID256291596

P50authorJulie AhringerQ15709495
Ericca L StamperQ55446269
Abby DernburgQ43167372
P2093author name stringAnne M Villeneuve
Stacia E Rodenbusch
Simona Rosu
P2860cites workDirect Coupling Between Meiotic DNA Replication and Recombination InitiationQ58486289
Spo11-accessory proteins link double-strand break sites to the chromosome axis in early meiotic recombinationQ64386697
Meiotic recombination proteins localize to linear elements in Schizosaccharomyces pombeQ64388567
Interchromosomal effects on crossing over in DrosophilaQ76199547
An expanded inventory of conserved meiotic genes provides evidence for sex in Trichomonas vaginalisQ21092188
Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiaeQ24548535
C. elegans mre-11 is required for meiotic recombination and DNA repair but is dispensable for the meiotic G(2) DNA damage checkpointQ24602472
Meiotic double-strand breaks at the interface of chromosome movement, chromosome remodeling, and reductional divisionQ24646919
A link between meiotic prophase progression and crossover controlQ25257844
The spindle assembly checkpointQ27023697
ZHP-3 acts at crossovers to couple meiotic recombination with synaptonemal complex disassembly and bivalent formation in C. elegansQ27313630
Matefin/SUN-1 phosphorylation is part of a surveillance mechanism to coordinate chromosome synapsis and recombination with meiotic progression and chromosome movementQ27324259
Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosisQ27345390
Cdc7-dependent phosphorylation of Mer2 facilitates initiation of yeast meiotic recombinationQ27929793
Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein familyQ27930009
Spatial organization and dynamics of the association of Rec102 and Rec104 with meiotic chromosomesQ27930842
Antiviral protein Ski8 is a direct partner of Spo11 in meiotic DNA break formation, independent of its cytoplasmic role in RNA metabolismQ27931005
Bypass of a meiotic checkpoint by overproduction of meiotic chromosomal proteinsQ27932278
Cyclin-dependent kinase directly regulates initiation of meiotic recombinationQ27933030
Synaptonemal complex assembly in C. elegans is dispensable for loading strand-exchange proteins but critical for proper completion of recombinationQ47069553
A component of C. elegans meiotic chromosome axes at the interface of homolog alignment, synapsis, nuclear reorganization, and recombination.Q47827981
Meiotic DNA breaks associated with recombination in S. pombeQ47847394
A gene expression map for Caenorhabditis elegans.Q48342750
Comparative Genomics of Hemiascomycete Yeasts: Genes Involved in DNA Replication, Repair, and RecombinationQ58377015
xnd-1 regulates the global recombination landscape in Caenorhabditis elegans.Q34610168
mei-P22 encodes a chromosome-associated protein required for the initiation of meiotic recombination in Drosophila melanogaster.Q34615978
Budding yeast ATM/ATR control meiotic double-strand break (DSB) levels by down-regulating Rec114, an essential component of the DSB-machinery.Q34795521
The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance.Q34945606
Nuclear reorganization and homologous chromosome pairing during meiotic prophase require C. elegans chk-2.Q35079512
Pairing centers recruit a Polo-like kinase to orchestrate meiotic chromosome dynamics in C. elegansQ35128564
Correlation between premeiotic DNA replication and chromatin transition at yeast recombination initiation sitesQ35164419
Chromosome choreography: the meiotic balletQ35195590
Transgene-mediated cosuppression in the C. elegans germ line.Q35197391
Spo11 and the Formation of DNA Double-Strand Breaks in MeiosisQ35212439
Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repairQ35503860
HIM-8 binds to the X chromosome pairing center and mediates chromosome-specific meiotic synapsisQ35619440
Chromosome sites play dual roles to establish homologous synapsis during meiosis in C. elegansQ35619465
Meiotic double-strand breaks occur once per pair of (sister) chromatids and, via Mec1/ATR and Tel1/ATM, once per quartet of chromatidsQ35647513
The impressionistic landscape of meiotic recombinationQ35686742
Where the crossovers are: recombination distributions in mammals.Q35778662
Synapsis-dependent and -independent mechanisms stabilize homolog pairing during meiotic prophase in C. elegansQ35804006
COSA-1 reveals robust homeostasis and separable licensing and reinforcement steps governing meiotic crossoversQ35919527
A conserved function for a Caenorhabditis elegans Com1/Sae2/CtIP protein homolog in meiotic recombinationQ36274716
AtPRD1 is required for meiotic double strand break formation in Arabidopsis thaliana.Q36439070
Cytological analysis of meiosis in Caenorhabditis elegansQ36816851
Germline chromatinQ37020713
Germline survival and apoptosisQ37264487
Programmed induction of DNA double strand breaks during meiosis: setting up communication between DNA and the chromosome structureQ38073468
Meiotic segregation, synapsis, and recombination checkpoint functions require physical interaction between the chromosomal proteins Red1p and Hop1pQ39455264
HTP-1-dependent constraints coordinate homolog pairing and synapsis and promote chiasma formation during C. elegans meiosisQ39705513
HTP-1 coordinates synaptonemal complex assembly with homolog alignment during meiosis in C. elegansQ39705533
MAQGene: software to facilitate C. elegans mutant genome sequence analysisQ40017452
Chromosome cores and chromatin at meiotic prophaseQ41628001
Condensins regulate meiotic DNA break distribution, thus crossover frequency, by controlling chromosome structureQ41948641
Meiotic chromosome homology search involves modifications of the nuclear envelope protein Matefin/SUN-1.Q43242461
C. elegans HIM-17 links chromatin modification and competence for initiation of meiotic recombinationQ45021539
A family of zinc-finger proteins is required for chromosome-specific pairing and synapsis during meiosis in C. elegans.Q45933828
HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosisQ47068681
Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.Q47069195
A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegansQ47069275
Genetic and cytological characterization of the recombination protein RAD-51 in Caenorhabditis elegansQ47069371
Physical and functional interactions among basic chromosome organizational features govern early steps of meiotic chiasma formationQ27933968
Saccharomyces cerevisiae Mer2, Mei4 and Rec114 form a complex required for meiotic double-strand break formationQ27934989
Interactions between Mei4, Rec114, and other proteins required for meiotic DNA double-strand break formation in Saccharomyces cerevisiaeQ27935897
Catalysis of ATP-dependent homologous DNA pairing and strand exchange by yeast RAD51 proteinQ27937922
Caenorhabditis elegans msh-5 is required for both normal and radiation-induced meiotic crossing over but not for completion of meiosisQ28140164
Stage-specific effects of X-irradiation on yeast meiosisQ28270209
Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsisQ28279936
Temporal comparison of recombination and synaptonemal complex formation during meiosis in S. cerevisiaeQ28306536
Positional cloning and characterization of Mei1, a vertebrate-specific gene required for normal meiotic chromosome synapsis in miceQ28512598
Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanismsQ28585141
Functional conservation of Mei4 for meiotic DNA double-strand break formation from yeasts to miceQ28586489
Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1.Q28594654
Robust crossover assurance and regulated interhomolog access maintain meiotic crossover numberQ28729155
ATM controls meiotic double-strand-break formationQ28742900
C. elegans germ cells switch between distinct modes of double-strand break repair during meiotic prophase progressionQ28756805
Un ménage à quatre: the molecular biology of chromosome segregation in meiosisQ29615266
An atypical topoisomerase II from Archaea with implications for meiotic recombinationQ29618230
Meiotic chromosomes: integrating structure and functionQ29618524
Mechanism and control of meiotic recombination initiationQ29618789
Cdc28-Clb5 (CDK-S) and Cdc7-Dbf4 (DDK) collaborate to initiate meiotic recombination in yeastQ29976896
X-chromosome silencing in the germline of C. elegansQ30412367
Crossover distribution and frequency are regulated by him-5 in Caenorhabditis elegansQ30421573
The HORMA domain: a common structural denominator in mitotic checkpoints, chromosome synapsis and DNA repairQ32010161
A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thalianaQ33504549
Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenesQ33891354
Dominant X-chromosome nondisjunction mutants of Caenorhabditis elegans.Q33948873
A cis-acting locus that promotes crossing over between X chromosomes in Caenorhabditis elegansQ33962654
Identification and cloning of unc-119, a gene expressed in the Caenorhabditis elegans nervous systemQ33966197
The synaptonemal complex shapes the crossover landscape through cooperative assembly, crossover promotion and crossover inhibition during Caenorhabditis elegans meiosisQ34131609
Meiotic recombination hot spots and cold spotsQ34238005
SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germlineQ34395310
Regulation of meiotic recombination and prophase I progression in mammalsQ34464620
A conserved checkpoint monitors meiotic chromosome synapsis in Caenorhabditis elegansQ34474546
Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS.Q34605661
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectCaenorhabditis elegansQ91703
Double-Strand Break factor CELE_F26H11.6Q29806341
P304page(s)e1003679
P577publication date2013-01-01
P1433published inPLOS GeneticsQ1893441
P1476titleIdentification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint
P478volume9

Reverse relations

cites work (P2860)
Q46110383A Surveillance System Ensures Crossover Formation in C. elegans.
Q57793791A chromatin-associated protein required for inducing and limiting meiotic DNA double-strand break formation
Q35156707A quality control mechanism coordinates meiotic prophase events to promote crossover assurance
Q64387176ATM and ATR Influence Meiotic Crossover Formation Through Antagonistic and Overlapping Functions in
Q49886701Age-Dependent Alterations in Meiotic Recombination Cause Chromosome Segregation Errors in Spermatocytes.
Q47665906Asy2/Mer2: an evolutionarily conserved mediator of meiotic recombination, pairing, and global chromosome compaction.
Q58084802BRCA1-BARD1 associate with the synaptonemal complex and pro-crossover factors and influence RAD-51 dynamics during Caenorhabditis elegans meiosis
Q37656154Control of Meiotic Crossovers: From Double-Strand Break Formation to Designation.
Q34242911DNA helicase HIM-6/BLM both promotes MutSγ-dependent crossovers and antagonizes MutSγ-independent interhomolog associations during caenorhabditis elegans meiosis.
Q92517918Environmentally-relevant exposure to diethylhexyl phthalate (DEHP) alters regulation of double-strand break formation and crossover designation leading to germline dysfunction in Caenorhabditis elegans
Q27319242Evidence that masking of synapsis imperfections counterbalances quality control to promote efficient meiosis
Q42373221Exploring Potential Germline-Associated Roles of the TRIM-NHL Protein NHL-2 Through RNAi Screening
Q33725749Functional characterization of the meiosis-specific DNA double-strand break inducing factor SPO-11 from C. elegans.
Q28658207Homologue engagement controls meiotic DNA break number and distribution
Q90647086Identification of novel synaptonemal complex components in C. elegans
Q61455332Initiation of Meiotic Development Is Controlled by Three Post-transcriptional Pathways in
Q37513959LINC complexes promote homologous recombination in part through inhibition of nonhomologous end joining
Q35582992MEI4 – a central player in the regulation of meiotic DNA double-strand break formation in the mouse
Q36365224Manipulation of Karyotype in Caenorhabditis elegans Reveals Multiple Inputs Driving Pairwise Chromosome Synapsis During Meiosis
Q34931212Mechanism and regulation of meiotic recombination initiation
Q38676330Meiosis.
Q38618828Meiotic Recombination: The Essence of Heredity
Q37371435Meiotic recombination and the crossover assurance checkpoint in Caenorhabditis elegans
Q36322053Meiotic recombination modulates the structure and dynamics of the synaptonemal complex during C. elegans meiosis.
Q60045774Mouse REC114 is essential for meiotic DNA double-strand break formation and forms a complex with MEI4
Q64096730Persistent DNA-break potential near telomeres increases initiation of meiotic recombination on short chromosomes
Q47313631Phosphorylation of the synaptonemal complex protein SYP-1 promotes meiotic chromosome segregation
Q99727644Poly(ADP-ribose) glycohydrolase coordinates meiotic DNA double-strand break induction and repair independent of its catalytic activity
Q39155608Prophase I: Preparing Chromosomes for Segregation in the Developing Oocyte
Q27313309Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age
Q33779559Pseudosynapsis and decreased stringency of meiotic repair pathway choice on the hemizygous sex chromosome of Caenorhabditis elegans males
Q38271059Self-organization of meiotic recombination initiation: general principles and molecular pathways
Q57189944Shugoshin Is Essential for Meiotic Prophase Checkpoints in C. elegans
Q98784895Surveillance of cohesin-supported chromosome structure controls meiotic progression
Q39412683Synaptonemal Complex Components Are Required for Meiotic Checkpoint Function in Caenorhabditis elegans
Q30606317Synaptonemal complex extension from clustered telomeres mediates full-length chromosome pairing in Schmidtea mediterranea.
Q34945606The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance.
Q36218780The Chromosome Axis Mediates Feedback Control of CHK-2 to Ensure Crossover Formation in C. elegans
Q55221543The conserved LEM-3/Ankle1 nuclease is involved in the combinatorial regulation of meiotic recombination repair and chromosome segregation in Caenorhabditis elegans.
Q34248122The meiotic checkpoint network: step-by-step through meiotic prophase
Q37562095The p53-like Protein CEP-1 Is Required for Meiotic Fidelity in C. elegans
Q58084799The tumor suppressor BRCA1-BARD1 complex localizes to the synaptonemal complex and regulates recombination under meiotic dysfunction in Caenorhabditis elegans
Q42741313To Break or Not To Break: Sex Chromosome Hemizygosity During Meiosis in Caenorhabditis
Q38563613Whole genome sequencing and the transformation of C. elegans forward genetics

Search more.