Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

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Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PBIO.1000355
P3181OpenCitations bibliographic resource ID2810301
P932PMC publication ID2854129
P698PubMed publication ID20405001
P5875ResearchGate publication ID43202288

P50authorThierry CoppolaQ55172174
Alice GuyonQ55186600
Marc BorsottoQ56885107
Jean-Louis NahonQ59158423
Emmanuel DevalQ61037757
Jean MazellaQ67276836
Gabriella GobbiQ41333335
P2093author name stringEric Chevet
Sophie Béraud-Dufour
Guillaume Lucas
Olivier Pétrault
Catherine Heurteaux
Grégory Conductier
Carine Gandin
Catherine Widmann
Said Taouji
Alain Corinus
Malika El-Yacoubi
P2860cites workThe 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptorQ22003873
Lifetime Prevalence and Age-of-Onset Distributions of DSM-IV Disorders in the National Comorbidity Survey ReplicationQ22253034
The sortilin cytoplasmic tail conveys Golgi-endosome transport and binds the VHS domain of the GGA2 sorting proteinQ24291185
Sortilin is essential for proNGF-induced neuronal cell deathQ24312692
TASK, a human background K+ channel to sense external pH variations near physiological pHQ24314854
Sortilin controls intracellular sorting of brain-derived neurotrophic factor to the regulated secretory pathway.Q24532072
A mammalian two pore domain mechano-gated S-like K+ channelQ24533276
Propeptide cleavage conditions sortilin/neurotensin receptor-3 for ligand bindingQ24533549
The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilinQ24594134
Hippocampal atrophy in recurrent major depressionQ24598190
The molecular neurobiology of depressionQ24656261
Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microgliaQ28211177
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Pharmacogenetic analysis of genes implicated in rodent models of antidepressant response: association of TREK1 and treatment resistance in the STAR(*)D studyQ28269390
Doublecortin expression levels in adult brain reflect neurogenesisQ28302922
Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous systemQ28567151
cAMP response element-mediated gene transcription is upregulated by chronic antidepressant treatment.Q51401037
Effects of antidepressant drugs on a quickly-learned conditioned-suppression response in mice.Q51828214
Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.Q52012874
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Stress-induced changes attributable to the sympathetic nervous system during experimental influenza viral infection in DBA/2 inbred mouse strainQ57072422
Deletion of the background potassium channel TREK-1 results in a depression-resistant phenotypeQ60710783
The tail suspension test: a new method for screening antidepressants in miceQ69947780
TREKing toward new antidepressantsQ80176419
Fast-acting antidepressants: are we nearly there?Q80220371
Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNSQ28569630
AKAP150, a switch to convert mechano-, pH- and arachidonic acid-sensitive TREK K(+) channels into open leak channelsQ28592333
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Molecular and functional properties of two-pore-domain potassium channels.Q33923164
Increasing hippocampal neurogenesis: a novel mechanism for antidepressant drugsQ36002843
TREK-1 is a heat-activated background K(+) channelQ36246837
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Mechanisms underlying excitatory effects of group I metabotropic glutamate receptors via inhibition of 2P domain K+ channelsQ36266895
Current Screens Based on the AlphaScreen Technology for Deciphering Cell Signalling PathwaysQ37236182
The Vps10p-domain receptor family.Q37478180
Animal models of 'anxiety': where next?Q40833774
Hexose transport stimulation and membrane redistribution of glucose transporter isoforms in response to cholera toxin, dibutyryl cyclic AMP, and insulin in 3T3-L1 adipocytesQ41727730
5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphé nucleus 5-HT neuronal activityQ42526750
Chronic antidepressant administration increases the expression of cAMP response element binding protein (CREB) in rat hippocampus.Q42556936
Assay Optimization and Screening of RNA-Protein Interactions by AlphaScreen.Q46313840
Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatmentQ46587013
Biochemical clustering of monomeric GTPases of the Ras superfamily.Q47068718
Long-term antidepressant treatments result in a tonic activation of forebrain 5-HT1A receptors.Q48346442
Mtap2 is a constituent of the protein network that regulates twik-related K+ channel expression and trafficking.Q48478462
Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptorsQ48668858
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectPotassium channel, subfamily K, member 2Q21494817
Sortilin 1Q21990393
P304page(s)e1000355
P577publication date2010-04-13
P1433published inPLOS BiologyQ1771695
P1476titleSpadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design
P478volume8