Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms

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Different characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2012PLoSO...751096T
P356DOI10.1371/JOURNAL.PONE.0051096
P3181OpenCitations bibliographic resource ID2573615
P932PMC publication ID3517587
P698PubMed publication ID23236438
P5875ResearchGate publication ID233909751

P50authorJulie WebsterQ57498315
Robert G. PartonQ30347571
Jennifer H. GunterQ42798278
Jonathan P. WhiteheadQ42798286
Viola OorschotQ45929277
P2093author name stringElaine C Thomas
Nicole L Schieber
P2860cites workInduction of cytoplasmic rods and rings structures by inhibition of the CTP and GTP synthetic pathway in mammalian cellsQ21090963
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Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivoQ24307563
Autosomal dominant retinitis pigmentosa mutations in inosine 5'-monophosphate dehydrogenase type I disrupt nucleic acid bindingQ24534912
Bateman domains and adenosine derivatives form a binding contractQ24614437
CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutationsQ24614590
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Microtubule-assisted mechanism for functional metabolic macromolecular complex formationQ24633198
Spectrum and frequency of mutations in IMPDH1 associated with autosomal dominant retinitis pigmentosa and leber congenital amaurosisQ24642869
IMP dehydrogenase type 1 associates with polyribosomes translating rhodopsin mRNAQ24643480
A quantitative atlas of mitotic phosphorylationQ24646817
Retinal isoforms of inosine 5'-monophosphate dehydrogenase type 1 are poor nucleic acid binding proteinsQ24647325
A regulatory role of the Bateman domain of IMP dehydrogenase in adenylate nucleotide biosynthesisQ24655404
Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosaQ24655474
Crystal structure of human type II inosine monophosphate dehydrogenase: implications for ligand binding and drug designQ27617777
Characteristics and crystal structure of bacterial inosine-5'-monophosphate dehydrogenaseQ27617878
Nucleotide recognition by the cytoplasmic domain of the human chloride transporter ClC-5Q27643450
Structure of a CBS-domain pair from the regulatory gamma1 subunit of human AMPK in complex with AMP and ZMPQ27644573
Binding of S-methyl-5'-thioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pairQ27658735
Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acidQ27733135
UCSF Chimera--a visualization system for exploratory research and analysisQ27860666
A single method for cryofixation and correlative light, electron microscopy and tomography of zebrafish embryosQ50610623
Expression, purification, and characterization of inosine 5'-monophosphate dehydrogenase from Borrelia burgdorferi.Q54559588
AMPK is a direct adenylate charge-regulated protein kinase.Q54580866
Human IMP dehydrogenase. Kinetics and regulatory propertiesQ68699786
IMP dehydrogenase. II. Purification and properties of the enzyme from Yoshida sarcoma ascites tumor cellsQ72569155
Global, in vivo, and site-specific phosphorylation dynamics in signaling networksQ27864128
Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation.Q27933749
Two distinct cDNAs for human IMP dehydrogenaseQ28115579
Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor bindingQ28117820
Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal regionQ28214482
Regulated localization of Rab18 to lipid droplets: effects of lipolytic stimulation and inhibition of lipid droplet catabolismQ28275690
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Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAsQ28283817
Characterisation of inosine monophosphate dehydrogenase expression during retinal development: differences between variants and isoformsQ28580218
Characterization of human type I and type II IMP dehydrogenasesQ28623113
Biochemical analysis of the modular enzyme inosine 5'-monophosphate dehydrogenaseQ30175322
Modern approaches for ultrastructural analysis of the zebrafish embryoQ33703193
Identification of an IMPDH1 mutation in autosomal dominant retinitis pigmentosa (RP10) revealed following comparative microarray analysis of transcripts derived from retinas of wild-type and Rho(-/-) miceQ34116773
Metabolic enzyme IMPDH is also a transcription factor regulated by cellular stateQ34278581
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.Q34300660
Tissue-differential expression of two distinct genes for human IMP dehydrogenase (E.C.1.1.1.205).Q34322414
The structure of a domain common to archaebacteria and the homocystinuria disease proteinQ34415436
Reversible compartmentalization of de novo purine biosynthetic complexes in living cellsQ34767701
The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnoverQ36517922
Regulation of IMP dehydrogenase gene expression by its end products, guanine nucleotidesQ36741046
AMPK functions as an adenylate charge-regulated protein kinase.Q37979423
IMP dehydrogenase, an enzyme linked with proliferation and malignancyQ39938931
Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.Q40358854
Conformational changes and stabilization of inosine 5'-monophosphate dehydrogenase associated with ligand binding and inhibition by mycophenolic acidQ42634081
Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesityQ42798251
Insulin and oleate promote translocation of inosine-5' monophosphate dehydrogenase to lipid bodiesQ42825697
Cross-talk between the catalytic core and the regulatory domain in cystathionine β-synthase: study by differential covalent labeling and computational modelingQ42826852
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channelsQ46606848
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)e51096
P577publication date2012-01-01
P1433published inPLOS OneQ564954
P1476titleDifferent characteristics and nucleotide binding properties of inosine monophosphate dehydrogenase (IMPDH) isoforms
P478volume7

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