Abstract is: Glycocyamine (or guanidinoacetate) is a metabolite of glycine in which the amino group has been converted into a guanidine by guanylation (transfer of a guanidine group from arginine). In vertebrate organism it is then transformed into creatine by methylation. Glycocyamine is used as a supplement and as a feed additive in poultry farming. However, the metabolism of creatine from glycocyamine in the liver causes a depletion of methyl groups. This causes homocysteine levels to rise, which has been shown to produce cardiovascular and skeletal problems. Glycocyamine plays a role in the metabolism of the amino acids serine, threonine and proline.
| P4149 | conjugate base | guanidinoacetate(1-) | Q35970787 |
| P703 | found in taxon | Prunus persica | Q13189 |
| Eriobotrya japonica | Q41505 | ||
| mandarin orange | Q125337 | ||
| Diospyros virginiana | Q158356 | ||
| Malus pumila | Q158657 | ||
| brown rat | Q184224 | ||
| Malus domestica | Q18674606 | ||
| Citrus × deliciosa | Q20686225 | ||
| Citrus unshiu | Q875262 | ||
| Chrysosporum ovalisporum | Q67336757 | ||
| Hippospongia communis | Q3384867 | ||
| Homo sapiens | Q15978631 | ||
| P2067 | mass | 117.054 | |
| P2868 | subject has role | primary metabolite | Q3333419 |
| affinity labels | Q50429801 | ||
| P6185 | tautomer of | guanidinoacetic acid zwitterion | Q106345629 |
| Q44057484 | Amino Acid metabolism |
| Q76750081 | Biochemical pathways: part I |
| Q30102291 | amino acid metabolism |
| Q50295088 | arginine + glycine => ornithine + guanidoacetate |
| Q50295089 | guanidinoacetate + S-adenosylmethionine => creatine + S-adenosylhomocysteine |
| Q28031281 | urea cycle and metabolism of amino groups |
| Q29614690 | A community-driven global reconstruction of human metabolism. |
| Q38593983 | Advanced physiological roles of guanidinoacetic acid. |
| Q57864201 | An alternative mechanism for guanidinoacetic acid to affect methylation cycle |
| Q33455085 | Annotation of the human adult urinary metabolome and metabolite identification using ultra high performance liquid chromatography coupled to a linear quadrupole ion trap-Orbitrap mass spectrometer |
| Q38563001 | Cellular bioenergetics of guanidinoacetic acid: the role of mitochondria. |
| Q36540109 | Creatine metabolism and safety profiles after six-week oral guanidinoacetic acid administration in healthy humans |
| Q102144008 | Dataset of levels and masses of lipid species in healthy, asymptomatic and symptomatic leaves of vitis vinifera L. 'Malvasia fina' affected by ESCA complex disease |
| Q115784055 | Dysregulation of Streptococcus pneumoniae zinc homeostasis breaks ampicillin resistance in a pneumonia infection model |
| Q85659624 | Effect of feeding guanidinoacetic acid and L-arginine on the fertility rate and sperm penetration in the perivitelline layer of aged broiler breeder hens |
| Q41742432 | First evidence of accumulation in cyanobacteria of guanidinoacetate, a precursor of the toxin cylindrospermopsin |
| Q104943098 | Guanidine Compounds in Fruit Trees and Their Seasonal Variations in Citrus (Citrus unshiu Marc.) |
| Q38601629 | Guanidinoacetic acid as a performance-enhancing agent |
| Q51307883 | Guanidinoacetic acid loading affects plasma γ-aminobutyric acid in healthy men. |
| Q36087847 | Low-Dose Creatine Supplementation Lowers Plasma Guanidinoacetate, but Not Plasma Homocysteine, in a Double-Blind, Randomized, Placebo-Controlled Trial |
| Q42146838 | Mild guanidinoacetate increase under partial guanidinoacetate methyltransferase deficiency strongly affects brain cell development. |
| Q35777605 | Mutation in the Monocarboxylate Transporter 12 Gene Affects Guanidinoacetate Excretion but Does Not Cause Glucosuria |
| Q104909419 | N-haltige Inhaltsstoffe des PferdeschwammesHippospongia equina |
| Q40410050 | Oxidant-Antioxidant Capacity of Dietary Guanidinoacetic Acid. |
| Q113954134 | Phosphoproteomic and Metabolomic Profiling Uncovers the Roles of CcPmk1 in the Pathogenicity of Cytospora chrysosperma |
| Q41036463 | Prevalence of Creatine Deficiency Syndromes in Children With Nonsyndromic Autism |
| Q28601559 | Recon 2.2: from reconstruction to model of human metabolism |
| Q41524602 | Single-dose oral guanidinoacetic acid exhibits dose-dependent pharmacokinetics in healthy volunteers |
| Q57863926 | Six-Week Oral Guanidinoacetic Acid Administration Improves Muscular Performance in Healthy Volunteers |
| Q86490280 | Synthesis of guanidinoacetate and creatine from amino acids by rat pancreas |
| Q82834275 | Urinary excretion of guanidinoacetic acid in rats with diabetic nephropathy |
| Q45088482 | Urinary guanidinoacetic acid excretion as an indicator of gentamicin nephrotoxicity in rats |
| Q82579234 | N-(Diaminomethylidene)(~13~C_2_)glycine | subclass of | P279 |
| Q35970787 | guanidinoacetate(1-) | conjugate acid | P4147 |
| Q106345629 | guanidinoacetic acid zwitterion | tautomer of | P6185 |
| Category:Glycocyamine | wikimedia | |
| azb | قلیکوسیامین | wikipedia |
| Guanidinoessigsäure | wikipedia | |
| Glycocyamine | wikipedia | |
| Glicociamina | wikipedia | |
| Persian (fa / Q9168) | گلیکوسیامین | wikipedia |
| Glykosyamiini | wikipedia | |
| Glycocyamine | wikipedia | |
| gl | Glicociamina | wikipedia |
| グアニジノ酢酸 | wikipedia | |
| 글리코사이아민 | wikipedia | |
| Guanidinoazijnzuur | wikipedia | |
| Serbo-Croatian (sh / Q9301) | Glikociamin | wikipedia |
| Glikocijamin | wikipedia | |
| 胍基乙酸 | wikipedia |
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