| scholarly article | Q13442814 |
| P50 | author | Gordon J. Freeman | Q27088375 |
| P2093 | author name string | Arash Grakoui | |
| Melissa K Osborn | |||
| Jeffrey L Lennox | |||
| Kimberly A Workowski | |||
| Mohammad Wehbi | |||
| Chris C Ibegbu | |||
| Kamil Obideen | |||
| Huiming Hon | |||
| Henry Radziewicz | |||
| Holly L Hanson | |||
| P2860 | cites work | PD-L1 is induced in hepatocytes by viral infection and by interferon-α and -γ and mediates T cell apoptosis | Q57083098 |
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| L’inhibition de la voie PD-1 permet de restaurer les fonctions effectrices des lymphocytes spécifiques du VIH | Q59673903 | ||
| The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo | Q72641743 | ||
| Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death | Q24293504 | ||
| Sustained Dysfunction of Antiviral CD8+ T Lymphocytes after Infection with Hepatitis C Virus | Q27469800 | ||
| Regulatory T cells suppress in vitro proliferation of virus-specific CD8+ T cells during persistent hepatitis C virus infection | Q27469828 | ||
| Diminished frequency of hepatitis C virus specific interferon secreting CD4+ T cells in human immunodeficiency virus/hepatitis C virus coinfected patients | Q27477581 | ||
| PD-1 Expression in Acute Hepatitis C Virus (HCV) Infection Is Associated with HCV-Specific CD8 Exhaustion | Q27477628 | ||
| Impaired Hepatitis C Virus-Specific T Cell Responses and Recurrent Hepatitis C Virus in HIV Coinfection | Q27477797 | ||
| Increased hepatitis C virus (HCV)-specific CD4+CD25 + regulatory T lymphocytes and reduced HCV-specific CD4+ T cell response in HCV-infected patients with normal versus abnormal alanine aminotransferase levels | Q27478131 | ||
| Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression | Q27478366 | ||
| Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C | Q27480306 | ||
| Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction | Q27481027 | ||
| High Level of PD-1 Expression on Hepatitis C Virus (HCV)-Specific CD8+ and CD4+ T Cells during Acute HCV Infection, Irrespective of Clinical Outcome | Q27485454 | ||
| Identification and In Vitro Expansion of Functional Antigen-Specific CD25+ FoxP3+ Regulatory T Cells in Hepatitis C Virus Infection | Q27485897 | ||
| Analysis of successful immune responses in persons infected with hepatitis C virus | Q27860698 | ||
| PD-1 and its ligands in tolerance and immunity | Q28131650 | ||
| Determinants of viral clearance and persistence during acute hepatitis C virus infection | Q28131757 | ||
| PD-L2 is a second ligand for PD-1 and inhibits T cell activation | Q28202471 | ||
| Restoring function in exhausted CD8 T cells during chronic viral infection | Q28289222 | ||
| Epidemiology of hepatitis C: geographic differences and temporal trends | Q29615896 | ||
| PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression | Q29618956 | ||
| Analysis of a successful immune response against hepatitis C virus | Q29619507 | ||
| The prevalence of hepatitis C virus infection in the United States, 1999 through 2002 | Q29619974 | ||
| Possible mechanism involving T-lymphocyte response to non-structural protein 3 in viral clearance in acute hepatitis C virus infection | Q29620141 | ||
| Recurrence of hepatitis C virus after loss of virus-specific CD4(+) T-cell response in acute hepatitis C | Q29620791 | ||
| Impaired effector function of hepatitis C virus-specific CD8+ T cells in chronic hepatitis C virus infection | Q29620795 | ||
| Different clinical behaviors of acute hepatitis C virus infection are associated with different vigor of the anti-viral cell-mediated immune response | Q29620891 | ||
| Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B | Q33243937 | ||
| Mature T lymphocyte apoptosis--immune regulation in a dynamic and unpredictable antigenic environment | Q33652471 | ||
| The liver as a site of T-cell apoptosis: graveyard, or killing field? | Q33916575 | ||
| Lymphocyte-mediated cytotoxicity. | Q34542250 | ||
| Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction | Q34570127 | ||
| PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection | Q34570624 | ||
| CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells | Q34709777 | ||
| Hepatic T cells and liver tolerance | Q35038298 | ||
| Effects of IL-7 on memory CD8 T cell homeostasis are influenced by the timing of therapy in mice | Q36407358 | ||
| Signals required for programming effector and memory development by CD8+ T cells | Q36528952 | ||
| Life and death in peripheral T cells | Q36858872 | ||
| Selective expression of IL-7 receptor on memory T cells identifies early CD40L-dependent generation of distinct CD8+ memory T cell subsets | Q37682352 | ||
| Apoptosis of activated CD4+ and CD8+ T cells is enhanced by co-culture with hepatocytes expressing hepatitis C virus (HCV) structural proteins through FasL induction | Q40386139 | ||
| CD8(+) T-cell selection, function, and death in the primary immune response in vivo | Q40735898 | ||
| Therapy of hepatitis C: alpha interferon and ribavirin | Q41598827 | ||
| Programmed death-1 (PD-1) is a marker of germinal center-associated T cells and angioimmunoblastic T-cell lymphoma | Q42821039 | ||
| The magnitude and breadth of hepatitis C virus-specific CD8+ T cells depend on absolute CD4+ T-cell count in individuals coinfected with HIV-1. | Q42987939 | ||
| CD8+ cell responses to hepatitis C virus (HCV) in the liver of persons with HCV-HIV coinfection versus HCV monoinfection | Q42990421 | ||
| Differences in HCV-specific T cell responses between chronic HCV infection and HIV/HCV co-infection. | Q42996799 | ||
| Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses. | Q43000889 | ||
| Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis | Q43539775 | ||
| An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection. | Q43636357 | ||
| Epidemiologic research and the action plan for liver disease research | Q44032363 | ||
| Discordant expression of perforin and granzyme A in total and HIV-specific CD8 T lymphocytes of HIV infected children and adolescents | Q44626933 | ||
| Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection | Q44947174 | ||
| Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections | Q45733084 | ||
| Differential expression of human granzymes A, B, and K in natural killer cells and during CD8+ T cell differentiation in peripheral blood | Q46655432 | ||
| B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes. | Q47926434 | ||
| Three memory subsets of human CD8+ T cells differently expressing three cytolytic effector molecules. | Q51979277 | ||
| Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. | Q52004225 | ||
| Dynamics of intra-hepatic lymphocytes in chronic hepatitis C: enrichment for Valpha24+ T cells and rapid elimination of effector cells by apoptosis. | Q52036459 | ||
| Quantification and localisation of FOXP3+ T lymphocytes and relation to hepatic inflammation during chronic HCV infection. | Q53571602 | ||
| Fas / FasL system, IL-1beta expression and apoptosis in chronic HBV and HCV liver disease. | Q54542850 | ||
| P433 | issue | 20 | |
| P921 | main subject | apoptotic process | Q14599311 |
| hepatitis C | Q154869 | ||
| Hepatitis C virus | Q708693 | ||
| P304 | page(s) | 9808-22 | |
| P577 | publication date | 2008-10-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Impaired Hepatitis C Virus (HCV)-Specific Effector CD8+ T Cells Undergo Massive Apoptosis in the Peripheral Blood during Acute HCV Infection and in the Liver during the Chronic Phase of Infection | |
| P478 | volume | 82 |
| Q24301928 | A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection |
| Q37898079 | A spatial view of the CD8+ T-cell response: the case of HCV. |
| Q47593614 | According to Hepatitis C Virus (HCV) Infection Stage, Interleukin-7 Plus 4-1BB Triggering Alone or Combined with PD-1 Blockade Increases TRAF1low HCV-Specific CD8+ Cell Reactivity. |
| Q37805839 | Adaptive Immunity to the Hepatitis C Virus |
| Q42429110 | Adoptive transfer of splenocytes to study cell-mediated immune responses in hepatitis C infection using HCV transgenic mice |
| Q40522642 | Apoptotic Epitope-Specific CD8+ T Cells and Interferon Signaling Intersect in Chronic Hepatitis C Virus Infection |
| Q41342548 | B7-H4 mediates inhibition of T cell responses by activated murine hepatic stellate cells |
| Q37495787 | CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells |
| Q55472983 | CTLA‑4 interferes with the HBV‑specific T cell immune response (Review). |
| Q37560275 | Caspase inhibitors for the treatment of hepatitis C. |
| Q27490355 | Costimulatory molecule programmed death-1 in the cytotoxic response during chronic hepatitis C |
| Q41590197 | Dysfunctional HIV-specific CD8+ T cell proliferation is associated with increased caspase-8 activity and mediated by necroptosis |
| Q37964746 | Failure of innate and adaptive immune responses in controlling hepatitis C virus infection |
| Q38129763 | Functional attributes of responding T cells in HCV infection: the recent advances in engineering functional antiviral T cells. |
| Q34789276 | Galectin-9 and IL-21 mediate cross-regulation between Th17 and Treg cells during acute hepatitis C. |
| Q37454425 | HCV-specific immune responses induced by CIGB-230 in combination with IFN-α plus ribavirin |
| Q37462730 | HCV-specific interleukin-21+CD4+ T cells responses associated with viral control through the modulation of HCV-specific CD8+ T cells function in chronic hepatitis C patients. |
| Q37106235 | Hepatic enrichment and activation of myeloid dendritic cells during chronic hepatitis C virus infection |
| Q64944307 | Hepatitis C Virus Infection: Host⁻Virus Interaction and Mechanisms of Viral Persistence. |
| Q27488844 | Hepatitis C virus versus innate and adaptive immune responses: a tale of coevolution and coexistence |
| Q28082128 | Hepatitis C virus-specific cytotoxic T cell response restoration after treatment-induced hepatitis C virus control |
| Q37123414 | High production rates sustain in vivo levels of PD-1high simian immunodeficiency virus-specific CD8 T cells in the face of rapid clearance |
| Q36162835 | IL-7Rαlow memory CD8+ T cells are significantly elevated in patients with systemic lupus erythematosus |
| Q34178628 | Immune control and failure in HCV infection--tipping the balance |
| Q98237886 | Immunometabolism and HIV-1 pathogenesis: food for thought |
| Q38206528 | Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy? |
| Q41035955 | Innate and Adaptive Immune Responses in Chronic HCV Infection |
| Q26851685 | Innate and adaptive immune responses in HCV infections |
| Q83066590 | Interleukin (IL)-17/IL-22-producing T cells enriched within the liver of patients with chronic hepatitis C viral (HCV) infection |
| Q47613181 | Intrahepatic Vγ9Vδ2 T-cells from HCV-infected patients show an exhausted phenotype but can inhibit HCV replication. |
| Q34359990 | Liver immunology |
| Q30438106 | Liver is able to activate naïve CD8+ T cells with dysfunctional anti-viral activity in the murine system |
| Q37987860 | Living in the liver: hepatic infections |
| Q37255644 | Maintenance of Th1 hepatitis C virus (HCV)-specific responses in individuals with acute HCV who achieve sustained virological clearance after treatment |
| Q59350858 | Modulation of the Immune System in Chronic Hepatitis C and During Antiviral Interferon-Free Therapy |
| Q34338489 | PD-1 expression on peripheral CD8+ TEM/TEMRA subsets closely correlated with HCV viral load in chronic hepatitis C patients |
| Q42988040 | Persistent hepatitis C virus (HCV) infection impairs HCV-specific cytotoxic T cell reactivity through Mcl-1/Bim imbalance due to CD127 down-regulation. |
| Q34084126 | Rare birds in North America: acute hepatitis C cohorts |
| Q102075398 | Reconstitution of T follicular helper-humoral immune axis with elimination of hepatitis C virus |
| Q38097425 | Role of T cell death in maintaining immune tolerance during persistent viral hepatitis |
| Q45368686 | Role of the coinhibitory receptor cytotoxic T lymphocyte antigen-4 on apoptosis-Prone CD8 T cells in persistent hepatitis B virus infection |
| Q36911650 | Sustained hyperresponsiveness of dendritic cells is associated with spontaneous resolution of acute hepatitis C. |
| Q27487939 | Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade |
| Q35018680 | T lymphocytes from chronic HCV-infected patients are primed for activation-induced apoptosis and express unique pro-apoptotic gene signature |
| Q34127437 | T-Cell Dysfunction and Inhibitory Receptors in Hepatitis C Virus Infection |
| Q89454256 | Targeting p53 and histone methyltransferases restores exhausted CD8+ T cells in HCV infection |
| Q34364103 | Tim-3 expression on PD-1+ HCV-specific human CTLs is associated with viral persistence, and its blockade restores hepatocyte-directed in vitro cytotoxicity |
| Q24630036 | Transient CD86 expression on hepatitis C virus-specific CD8+ T cells in acute infection is linked to sufficient IL-2 signaling |
| Q33718267 | Virus-related liver cirrhosis: molecular basis and therapeutic options |
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