NMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptor

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NMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1110/PS.9.7.1282
P3181OpenCitations bibliographic resource ID4558215
P932PMC publication ID2144682
P698PubMed publication ID10933493
P5875ResearchGate publication ID12386172

P50authorNyoman KurniawanQ42690115
P2093author name stringR Smith
I M Brereton
C J Brown
P A Kroon
S Bieri
A R Atkins
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Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptorQ24563806
NMR solution structure of complement-like repeat CR8 from the low density lipoprotein receptor-related proteinQ27618138
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Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein EQ27663468
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Three-dimensional structure of the second cysteine-rich repeat from the human low-density lipoprotein receptorQ27729717
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Molecular basis of familial hypercholesterolaemia from structure of LDL receptor moduleQ27742097
Solution structure of human p8MTCP1, a cysteine-rich protein encoded by the MTCP1 oncogene, reveals a new alpha-helical assembly motifQ27748617
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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical featuresQ27860675
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Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutionsQ27860828
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A receptor-mediated pathway for cholesterol homeostasisQ29616158
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Complete cloning and sequencing of rat gp330/"megalin," a distinctive member of the low density lipoprotein receptor gene familyQ35809266
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Mutational analysis of the ligand binding domain of the low density lipoprotein receptorQ38346504
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Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteinsQ41757752
Estimating the relative populations of 3(10)-helix and alpha-helix in Ala-rich peptides: a hydrogen exchange and high field NMR studyQ43928659
The Trp23-Stop and Trp66-Gly mutations in the LDL receptor gene: common causes of familial hypercholesterolemia in DenmarkQ44174362
Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coliQ46266191
Analysis of main chain torsion angles in proteins: prediction of NMR coupling constants for native and random coil conformationsQ47630147
Folding, calcium binding, and structural characterization of a concatemer of the first and second ligand-binding modules of the low-density lipoprotein receptorQ47732365
Quality assessment of NMR structures: a statistical surveyQ47781173
NMR of modular proteinsQ47841993
First cysteine-rich repeat in ligand-binding domain of low density lipoprotein receptor binds Ca2+ and monoclonal antibodies, but not lipoproteins.Q52831885
LDL-receptor structure. Calcium cages, acid baths and recycling receptors.Q55067160
Solution structure of a polypeptide dimer comprising the fourth calcium-binding site of troponin C by nuclear magnetic resonance spectroscopyQ57202440
Unexpected consequences of deletion of the first two repeats of the ligand-binding domain from the low density lipoprotein receptor. Evidence from a human mutationQ71743453
Mutations of low-density-lipoprotein-receptor gene, variation in plasma cholesterol, and expression of coronary heart disease in homozygous familial hypercholesterolaemiaQ72218719
Calcium is essential for the structural integrity of the cysteine-rich, ligand-binding repeat of the low-density lipoprotein receptorQ74248737
Structural independence of ligand-binding modules five and six of the LDL receptorQ77293454
Characterization of the calcium site in two complement-like domains from the low-density lipoprotein receptor-related protein (LRP) and comparison with a repeat from the low-density lipoprotein receptorQ77628730
Phenotypic consequences of a deletion of exons 2 and 3 of the LDL receptor geneQ77927946
P433issue7
P921main subjectlipoproteinQ28350
ligand bindingQ61659151
P304page(s)1282-93
P577publication date2000-07-01
P1433published inProtein ScienceQ7251445
P1476titleNMR structure of a concatemer of the first and second ligand-binding modules of the human low-density lipoprotein receptor
P478volume9

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cites work (P2860)
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Q45739978VLDL receptor fragments of different lengths bind to human rhinovirus HRV2 with different stoichiometry. An analysis of virus-receptor complexes by capillary electrophoresis

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