The structure and function of human dipeptidyl peptidase IV, possessing a unique eight-bladed beta-propeller fold

scientific article (publication date: 21 March 2003)

The structure and function of human dipeptidyl peptidase IV, possessing a unique eight-bladed beta-propeller fold is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0006-291X(03)00258-4
P3181OpenCitations bibliographic resource ID4116647
P698PubMed publication ID12646248

P2093author name stringKiyoshi Kyono
Atsushi Yamamoto
Shigeru Sugiyama
Ryo Shimizu
Hideaki Shima
Koji Inaka
Chiaki Fukushima
Hajime Hiramatsu
Yutaka Higashiyama
P2860cites workProlyl OligopeptidaseQ56593808
Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted β propeller domainQ60617864
CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choiceQ24286950
Catalysis of serine oligopeptidases is controlled by a gating filter mechanismQ24522484
Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationQ26778405
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structuresQ26778412
The structure of TolB, an essential component of the tol-dependent translocation system, and its protein-protein interaction with the translocation domain of colicin E9Q27621344
The CCP4 suite: programs for protein crystallographyQ27861090
The HIV-1 gp120 inhibits the binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expressionQ28141057
Beta propellers: structural rigidity and functional diversityQ33801817
Protein folds propelled by diversityQ34272106
The prolyl oligopeptidase familyQ34578122
Novel sequences propel familiar foldsQ34590924
The primary structure of porcine liver acylamino acid-releasing enzyme deduced from cDNA sequencesQ35935840
Evolution of Proteolytic EnzymesQ40173671
Dipeptidylpeptidase IV and trypsin-like enzymatic degradation of human growth hormone-releasing hormone in plasmaQ40379465
Triggering of the proteinase dipeptidyl peptidase IV (CD26) amplifies human T lymphocyte proliferation.Q41677375
Reduced postprandial concentrations of intact biologically active glucagon-like peptide 1 in type 2 diabetic patients.Q51550359
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)849-54
P577publication date2003-03-21
P1433published inBiochemical and Biophysical Research CommunicationsQ864228
P1476titleThe structure and function of human dipeptidyl peptidase IV, possessing a unique eight-bladed beta-propeller fold
P478volume302

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cites work (P2860)
Q61818110A Novel Dipeptidyl Peptidase IV Inhibitory Tea Peptide Improves Pancreatic β-Cell Function and Reduces α-Cell Proliferation in Streptozotocin-Induced Diabetic Mice
Q27677875A Self-compartmentalizing Hexamer Serine Protease from Pyrococcus Horikoshii: SUBSTRATE SELECTION ACHIEVED THROUGH MULTIMERIZATION
Q27701492Anagliptin, a potent dipeptidyl peptidase IV inhibitor: its single-crystal structure and enzyme interactions
Q44726066Characterisation of human dipeptidyl peptidase IV expressed in Pichia pastoris. A structural and mechanistic comparison between the recombinant human and the purified porcine enzyme.
Q36095299Comprehensive analysis of the Co-structures of dipeptidyl peptidase IV and its inhibitor
Q53607590Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition.
Q27642932Crystal structure of human dipeptidyl peptidase IV in complex with a decapeptide reveals details on substrate specificity and tetrahedral intermediate formation
Q49370855Crystal structures of a bacterial dipeptidyl peptidase IV reveal a novel substrate recognition mechanism distinct from that of mammalian orthologues.
Q42001745Crystallization and preliminary X-ray characterization of prolyl tripeptidyl aminopeptidase from Porphyromonas gingivalis
Q41981737Crystallization and preliminary X-ray crystallographic studies of dipeptidyl aminopeptidase BII from Pseudoxanthomonas mexicana WO24.
Q41460026Crystallization and preliminary X-ray crystallographic studies of dipeptidyl peptidase 11 from Porphyromonas gingivalis.
Q36010087Crystallization and preliminary crystallographic analysis of porcine acylaminoacyl peptidase
Q36729115DPPIV inhibition: promising therapy for the treatment of type 2 diabetes
Q27652311Dipeptidyl Aminopeptidase IV from Stenotrophomonas maltophilia Exhibits Activity against a Substrate Containing a 4-Hydroxyproline Residue
Q24543939Dipeptidyl peptidases 8 and 9: specificity and molecular characterization compared with dipeptidyl peptidase IV
Q44304349Docking study of the precursor peptide of mastoparan onto its putative processing enzyme, dipeptidyl peptidase IV: a revisit to molecular ticketing
Q92001025Extracellular signaling in Dictyostelium
Q44997383His507 of acylaminoacyl peptidase stabilizes the active site conformation, not the catalytic intermediate
Q35690787Hot spot analysis for driving the development of hits into leads in fragment-based drug discovery
Q43035089Hydrophilic residues surrounding the S1 and S2 pockets contribute to dimerisation and catalysis in human dipeptidyl peptidase 8 (DP8).
Q27661330Induced-fit mechanism for prolyl endopeptidase
Q33927989Isolation of dipeptidyl peptidase IV (DP 4) isoforms from porcine kidney by preparative isoelectric focusing to improve crystallization.
Q24305686Modulation of Kv4.2 channel expression and gating by dipeptidyl peptidase 10 (DPP10)
Q39556441Molecular dynamics simulations of acylpeptide hydrolase bound to chlorpyrifosmethyl oxon and dichlorvos
Q43104954N-linked glycosylation of dipeptidyl peptidase IV (CD26): effects on enzyme activity, homodimer formation, and adenosine deaminase binding.
Q47670361Periplasmic form of dipeptidyl aminopeptidase IV from Pseudoxanthomonas mexicana WO24: purification, kinetic characterization, crystallization and X-ray crystallographic analysis.
Q36268544Predicting DPP-IV inhibitors with machine learning approaches.
Q35206949Prolyl peptidases: a serine protease subfamily with high potential for drug discovery.
Q34651364Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV.
Q27683781S46 Peptidases are the First Exopeptidases to be Members of Clan PA
Q27665946Structure and Catalysis of Acylaminoacyl Peptidase: CLOSED AND OPEN SUBUNITS OF A DIMER OLIGOPEPTIDASE
Q44979431The crystal structure of human dipeptidyl peptidase IV (DPPIV) complex with diprotin A.
Q33934034The emergence of the Middle East respiratory syndrome coronavirus
Q44919467Tyrosine 547 constitutes an essential part of the catalytic mechanism of dipeptidyl peptidase IV.

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