Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: Crystal structures and mutation studies of bovine neurophysin-I

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Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: Crystal structures and mutation studies of bovine neurophysin-I is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1110/PS.062444807
P932PMC publication ID2222833
P698PubMed publication ID17192588
P5875ResearchGate publication ID6607242

P2093author name stringJin Wu
Xintian Li
Hunjoong Lee
Esther Breslow
P2860cites workEpidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interfaceQ24529941
Structures of an unliganded neurophysin and its vasopressin complex: Implications for binding and allosteric mechanismsQ27634280
NMR analysis of the monomeric form of a mutant unliganded bovine neurophysin: comparison with the crystal structure of a neurophysin dimerQ27638913
Crystal structure of a bovine neurophysin II dipeptide complex at 2.8 A determined from the single-wavelength anomalous scattering signal of an incorporated iodine atomQ27660338
Crystal structure of the neurophysin-oxytocin complexQ27732533
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Improved spectral resolution in cosy 1H NMR spectra of proteins via double quantum filteringQ29618846
Identification of 13 new mutations in the vasopressin-neurophysin II gene in 17 kindreds with familial autosomal dominant neurohypophyseal diabetes insipidusQ35882453
Identification of human neurophysins: complete amino acid sequences of MSEL- and VLDV-neurophysinsQ37611365
Molecular, thermodynamic, and biological aspects of recognition and function in neurophysin-hormone systems: a model system for the analysis of protein-peptide interactionsQ38144358
Identification and observation of alkyl proton resonances of the amino-terminal residues of bovine neurophysins. Evidence for conformational differences between neurophysin-I and neurophysin-IIQ39238918
Drug-biomolecule interactions: proton magnetic resonance studies of complex formation between bovine neurophysins and oxytocin at molecular levelQ40334268
A single base substitution in the coding region for neurophysin II associated with familial central diabetes insipidusQ40346052
Modulation of dimerization, binding, stability, and folding by mutation of the neurophysin subunit interface.Q40757726
Properties of human vasopressin precursor constructs: inefficient monomer folding in the absence of copeptin as a potential contributor to diabetes insipidusQ44946237
Interactions of oxytocin and vasopressin with bovine neurophysins I and II. Effects of hormone binding on the protein quaternary structure: a simple modelQ45886042
Small peptides as analogs of oxytocin and vasopressin in their interactions with bovine neurophysin-II.Q47905930
Bovine neurophysin dimerization and neurohypophyseal hormone binding.Q52758734
Molecular properties of the oxytocin/bovine neurophysin biosynthetic precursor. Studies using a semisynthetic precursor.Q54447099
NMR Investigation of Main-Chain Dynamics of the H80E Mutant of Bovine Neurophysin-I: Demonstration of Dimerization-Induced Changes at the Hormone-Binding Site†Q60130921
Slowly interchanging conformers of bovine neurophysin-I in the unliganded dimeric stateQ67589011
Binding and fluorescence studies of the relationship between neurophysin-peptide interaction and neurophysin self-association: an allosteric system exhibiting minimal cooperativityQ67939197
Structural requirements of peptide hormone binding for peptide-potentiated self-association of bovine neurophysin IIQ68506567
Dimerization of native and proteolytically modified neurophysins as monitored by proton magnetic resonance spectroscopy: proximity of tyrosine-49 to the subunit interfaceQ69685191
Partial digestion of neurophysins with proteolytic enzymes: unusual interactions between bovine neurophysin II and chymotrypsinQ70331556
Modulation of allosteric interactions in neurophysin induced by succinylation of serine-56 or cleavage of residues 1-8Q70480685
Stopped-flow investigation of nitrated bovine neurophysin monomer binding to oxytocinQ70728713
Expression, folding, and thermodynamic properties of the bovine oxytocin-neurophysin precursor: relationships to the intermolecular oxytocin-neurophysin complexQ73082858
Modulation of dimerization by residues distant from the interface in bovine neurophysin-IIQ73729599
Effects of diabetes insipidus mutations on neurophysin folding and functionQ73981370
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectcrystal structureQ895901
P304page(s)52-68
P577publication date2007-01-01
P1433published inProtein ScienceQ7251445
P1476titleContributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: Crystal structures and mutation studies of bovine neurophysin-I
P478volume16

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